• Archives of Pharmacal Research
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• 제26권7호
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• pp.569-574
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• 2003

Controlled-release amitriptyline pellets (ATP) were formulated and its oral bioavailability was assessed in human volunteers after oral administration under fasting conditions. Core pellets were prepared using a CF granulator by two different methods (powder layering and solvent spraying) and coated with Eudragit RS or RL 100. Physical characteristics and dissolution rates of core pellets and coated pellets were evaluated to optimize the formulation. Powder layering method resulted in a better surface morphology than solvent spraying method. However, physical properties of the products were poorer when prepared by powder layering method with respect to hardness, friability and density. The dissolution profile of amitriptyline coated with Eudragit RS 100 was comparable to that of commercially available amitriptyline enteric-coated pellets ($Saroten^{\circledR}$ retard). After the oral administration of both products at the dose of 50 mg, the mean maximum concentrations ($C_{max}$) were 36.4 and 29.7 ng/mL, and the mean areas under the concentration-time curve ($AUC_{0-96}$) were 1180.2 and 1010.7 ng.h/mL for ATP and Saroten retard, respectively. The time to reach the maximum concentrations ($T_{max}$) was 6 h for both formulations. Statistical evaluation suggested that ATP was bioequivalent to Saroten retard.

• 한국환경복원기술학회지
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• 제7권4호
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• pp.110-119
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• 2004

This research was conducted to develop spraying cultivation method using forest topsoils in order to restore the disturbed slopes. In November the researcher collected a depth of 5 cm of topsoils from a well developed forest, after the fallen leaves were cleared. The essential results of the research are as follows: In the case of using the forest topsoils, during the early stages of planting, time is necessary for the desired vegetation to reach a similar state to the vegetation being restored. The best possible effect is obtained through a method utilizing forest topsoil(30%)+loam silt soil(70%)+seeding with grasses and native plants including trees, shrubs, and herbs. Several plants such as Pinus densiftora, Potentilla fragarioides, Miscanthus sinensis, Erigeron canadensis seemed to be naturally emerged from the topsoils From this experiment, it was recommended that environment potential within topsoil should be comprehended. Also, topsoil deposit and gathering methods should be experimented properly.

• 대한디지털의료영상학회논문지
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• 제15권2호
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• pp.69-76
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• 2013

We checked the existence of bacteria at DR equipment, radiation generator and cassette in 'D university' to propose optimized management method for bacteria and disinfection at DR equipment, radiation generator and cassette at used in radiographic laboratory of the department of radiology. The infected region is treated by alcohol and cresol and compared before spraying and after spraying for 1, 3, 5 and 10 minutes. As time goes on, amount of bacteria colony decreases significantly. The Cresol is useful to disinfect the diminutive devices. However alcohol disinfection, at least 5 minutes later, and hand washing before practical training and shooting image is recommended due to the big and fixed radiography equipment which cause the soakage.

• 설비공학논문집
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• 제9권2호
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• pp.134-143
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• 1997

A theoretical and experimental study has been performed to investigate the characteristics of ice-slurry product. By diffusion-controlled model, the possibility of ice slurry has been theoretically anticipated. The water vapor evaporated from the surface of droplets is extracted continuously from the chamber by a vacuum pump. The droplet diameter was measured by silion immersed method. The ice slurry has been obtained by spraying droplets of ethylene-glycol aqueous solution in the chamber where pressure is maintained under the triple point of water. The droplet of which the diameter is $300{\mu}m$, and the initial temperature is $20^{\circ}C$, was changed into ice particle within the chamber of which the height is 1.33m.

• 한국세라믹학회지
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• 제38권7호
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• pp.602-607
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• 2001

Zirconia powder containing 3 mol% yttria (3Y-PSZ) was casted on the cast iron substrate by plasma spraying method. Coated specimens were then heat treated at 500$\^{C}$ in nitrogen plasma. Wear tests were performed on nitrogen heat treated and non heat treated samples at temperatures from 25$\^{C}$ to 600$\^{C}$. Wear results showed that the friction coefficient and the wear loss of both the treated and the non-treated samples showed maximum value at 400$\^{C}$. These results were explained by low temperature thermal degradation due to the monoclinic transformation. Nitrogen plasma treatment significantly improved the tribological performance. The effect of nitrogen heat treatment on tribological behavior was explained by the increased micro-hardness and decreased monoclinic faction.

• 한국분말재료학회지
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• 제16권1호
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• pp.56-62
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• 2009

The degree of WC decomposition and hardness of thermally sprayed WC-Co coatings are important factors determining the wear resistance of the coatings. In order to minimize the degree of decomposition and to increase hardness, the effects of processing parameters of high velocity oxyfuel(HVOF) spraying on various characteristics of nanostructured WC-12Co coating have been evaluated by an experimental design method. The HVOF sprayed WC-12Co coatings consisted of various carbide phases including WC, $W_2C$ and $W_3Co_3C$, with a much reduced carbon content. The degree of WC decomposition and decarburization was affected by changing barrel length and spray distance. The hardness of WC-Co coatings was strongly related to droplet temperature at substrate, and increased with increasing fuel addition and/or decreasing spray distance. The effective control of processing parameters was discussed in detail for manufacturing a high performance WC-Co coating.

• 한국분무공학회지
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• 제18권2호
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• pp.81-86
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• 2013

To comply with the regulation of the reinforcing Clean Air Conservation Act, it is necessary for the semiconductor manufacturers to develop effective low-concentration acid gas abatement system to treat the flue gas. The low-concentration acid gas was found to be harder to deal with than the high-concentration one. In this study, the effect of various potential treatments such as air-assist nozzle spraying, magnetizing the scrubbing water, and adding surfactants to spraying and scrubbing water were investigate through the application of the statistical ANCOVA method, which was proved to be very useful tool when the inlet concentration of acid gas could not be controlled precisely and it affected the removal efficiency of the abatement system.

• Journal of Biosystems Engineering
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• 제19권4호
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• pp.369-379
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• 1994

A computer vision system consisted of a microscope, a CCD camera, a frame grabber and a personal computer was used to analyze spraying pattern. An algorithm was developed for the system to measure size of droplets including overlapped droplets, to count number of droplets, and to estimate spray deposition in a certain area from the data obtained. A series of experiment was carried out to test validity of the algorithm. The experiment resulted that accuracy of the droplet size measurement, accuracy of counting the number of droplets and the estimation of spray deposition were within an acceptable range. It was concluded from the results that the computer vision system operated by the developed algorithm is very useful tool to analyze spraying pattern.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2016년도 춘계 학술논문 발표대회
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• pp.109-110
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• 2016

The recent introduction of Metal spraying method apply to construction and civil steel structure is increasing. In applying the metal spraying lining process of construction and civil steel structure to secure the adhesion strength between the metal thermal spray coating and the steel structure and the highest priority requirements are required bond strength test reliable measurement accordingly. In this study, by calculating the deposition intensity and the standard deviation, coefficient of variation corresponding to the bonding area, unlike the shape of the attachment we compared the results.

• Journal of Welding and Joining
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• 제7권4호
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• pp.46-55
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• 1989

Zirconia coatings are performed by the plasma spraying on the substrate of Al-Si alloy. In case of plasma sprayed ceramic coatings, it is important to control properly residual stress occurred during cooling process. Residual stress in coating layer varies with sprayed conditions and is influenced greatly by the coating layer thickness. Surface residual stress due to coating layer thickness is measured by X-ray diffraction method and the residual stress in coating layer is estimated by the deflection of coating layer when the restraint force in substrate was removed. When zirconia was coated on the substrate, tensile residual stress remains on zirconia coated surface layer. The tensile stress is increased to 0.35mm thickness and after 0.45mm thickness it is decreased abrouptly. A thick bond and composite coating reduce the zirconia surface stress and composite coating controls effectively the thick zirconia surface stress.