• Archives of Pharmacal Research
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• 제24권3호
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• pp.194-197
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• 2001

The phytochemical study of the aerial parts of Artemisia japonica ssp. littoricola (Asteraceae) led to the isolation of two acetylenic compounds, (3R)-dehydrofalcarinol (2) and (3R)-dehydrofalcarindiol (6), two sesquiterpenes, $1{\beta}$, $6{\alpha}$-dihydroxy-4(15)-eudesmene (5) and oplodiol (8), and four phenolic compounds, eugenol (1), vanillin (3), 3'-methoxy-4'- hydroxy-trrans-cinnamaldehyde (4) and p-hydroxyacetophenone (7). Their structures were determined by chemical and spectroscopic methods.

• Archives of Pharmacal Research
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• 제29권11호
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• pp.952-956
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• 2006

A phytochemical investigation of stems from Salvadora persica resulted in the first isolation of four benzylamides from a natural source. The isolated compounds were identified as butanediamide, $N^{1},\;N^{4}$-bis(phenylmethyl)-2(S)-hydroxy-butanediamide (1), N-benzyl-2-phenylacetamide (2), N-benzylbenzamide (3) and benzylurea (4). The structure elucidation was accomplished using spectroscopic methods, especially 2D NMR and HREIMS. Compound 2 revealed a significant inhibitory effect on human collagen-induced platelet aggregation, and a moderate antibacterial activity against Escherichia coli.

• Journal of the Korean Wood Science and Technology
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• 제25권4호
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• pp.1-9
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• 1997

The Abies koreana Wilson has been unique species of Korea and has not been clearly investigated about lignans of extractives. This studies have been carried out from the isolation and determination of lignans from alcoholic extractives in its xylem. Six lignans were isolated and their structures were determined by spectroscopic methods. They were two new compounds, (+)-koreslactol and (-)koreanol and four known compounds, lariciresinol p-coumarate, (+)-todolactol C, (-)-${\alpha}$-intermedianol, and (+)-pinoresinol.

• 생약학회지
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• 제29권1호
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• pp.44-47
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• 1998

From the 60% aqueous methanolic fraction of Moutan Cortex Radicis two hyaluronidase inhibitors were isolated and their structures were elucidated by spectroscopic methods. Their structures were identified as paeoniflorin (com-pound I) and oxypaeoniflorin (compound II). Compound I and II exhibited hyaluronidase inhibitory activities with $IC_{50}$ of 1.71 and 1.73mM, respectively.

• Natural Product Sciences
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• 제8권4호
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• pp.127-128
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• 2002

A flavone glycoside was isolated from the roots of Angelica gigas (Umbelliferae) and identified as diosmin $[diosmetin-7-O-{\alpha}-{_L}-rhamnopyranosyl \;(1{\rightarrow}6)-{\beta}-{_D}-glucopyranoside]$ by spectroscopic methods. This is the first report of a flavone gylcoside from Angelica species.

• Bulletin of the Korean Chemical Society
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• 제18권6호
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• pp.631-635
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• 1997

Four steroids including two novel compounds have been isolated from a sponge of the genus Tethya. All of the compounds possess a 5α,8α-epidioxy functionality as a common structural feature. Two new steroids, 1 and 2, possess a cyclopropyl ring at C-24(26) of the side chain. The structures of these compounds have been determined by combined spectroscopic methods.

• 약학회지
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• 제47권1호
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• pp.10-13
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• 2003

The phytochemical study of Cacalia koraiensis Nakai (Compositae) led to the isolation of eight compounds, $\beta$-sitosterol (1), stigmasterol (2), phytol (3), $\beta$-sitosterol-3-Ο-glucopyranoside (4), adenostylol (5), campesterol (6), germacradien-4$\alpha$-ol (7), and quercetin-3-rhamnoside (8). Their structures were established by chemical and spectroscopic methods. The cytotoxicity of the isolated compounds was evaluated by SRB assay against five cultured human tumor cell lines.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.135.1-135.1
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• 2003

We have previously reported three new oleanene-type glycosides and kudzusaponin $A_3$ methyl ester and subproside II methyl ester from the roots of Echinosophora koreensis. Further study has now led to the isolation of three known oleanen-type glycosides. sophoraflavoside I, azukisaponin V, and kudzusaponin $SA_3$ as their methyl esters. The structures of theses compounds were characterized by spectroscopic and chemical methods.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.258.2-258.2
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• 2003

Rhus verniciflua STOKES (RVS) belongs to Anacardiaceae and grows Korea, China and Japan. distributed in the northeastern Asia. Rhus verniciflua STOKES has been used for anthelmintic medicine, stomachache, emmenagogue and constipation in oriental medicine. From the EtOAc fraction of 70％ MeOH extracts, flavonoids were isolated by column chromatography using ODS, Sephadex LH-20 and silica gel. The structure of these compounds were identified on the $^1$H-NMR, $\^$13/C-NMR and FAB/MS spectroscopic methods.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.201.2-201.2
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• 2003

A novel lanostane-type triterpene, (24E)-3,4-seco-9${\beta}$H-lanosta- 4(28),7,24- triene- 3,26- dioic acid was isolated from Abies koreana (Pinaceae) which is a tall evergreen tree grown indigenously in southern Korea. The structure of this compound was characterized by spectroscopic methods. Cytotoxicity of the compound was evaluated in vitro using the SRB method, and it showed marginal activity against human cancer cell lines.