• Title/Summary/Keyword: specific field

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Comparative Molecular Field Analysis of Caspase-3 Inhibitors

  • Sathya, B.;Madhavan, Thirumurthy
    • Journal of Integrative Natural Science
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    • v.7 no.3
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    • pp.166-172
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    • 2014
  • Caspases, a family of cysteinyl aspartate-specific proteases plays a central role in the regulation and the execution of apoptotic cell death. Activation of caspases-3 stimulates a signaling pathway that ultimately leads to the death of the cell. Hence, caspase-3 has been proven to be an effective target for reducing the amount of cellular and tissue damage. In this work, comparative molecular field analysis (CoMFA) was performed on a series of 3, 4-dihydropyrimidoindolones derivatives which are inhibitors of caspase-3. The best predictions were obtained for CoMFA model ($q^2=0.676$, $r^2=0.990$). The predictive ability of test set ($r^2_{pred}$) was 0.688. Statistical parameters from the generated QSAR models indicated the data is well fitted and have high predictive ability. Our theoretical results could be useful to design novel and more potent caspase-3 derivatives.

Simulated Indoor Pass-by 시스템에서의 최적 Microphone Array 형태와 검증

  • Yu, Yun-Seon;Shirahashi, Yoshihiro;Morie, Daisuke
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2009.10a
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    • pp.225-228
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    • 2009
  • The simulated indoor pass-by noise measurement system is the tool to measure and evaluate the pass-by noise at the test laboratory, without doing measurement at the field. This measurement system can realize the precision measurement under the specific condition and overcome the limitations of the field measurement, i.e. weather conditions, repeatability, .. This measurement system is done in time domain process using the array techniques, which synchronizes the time signals. The reliability of the obtained result depends on the array shapes, which can generate the moving source effect. In this paper, the validations are checked focusing the time domain synchronization of the signals with the optimum microphone array shape.

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A Study on the Intellectual Structure Using Cocitation Analysis (논문의 동시인용을 통한 지적(知的)구조의 규명에 관한 연구)

  • Kim, Young-Jin
    • Journal of the Korean Society for information Management
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    • v.3 no.1
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    • pp.103-135
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    • 1986
  • In this thesis, author cocitation analysis with 45 authors in the field of sociology in general and document cocitation analysis in the specific area of family sociology were executed. The purpose of this study is to examine the meaning of bibliographic phenomena in Korean sociological literature by means of a new bibliometric technique, cocitation analysis, and to approach the intellectual structure of that field in view of multidimensional space.

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A Study on Stabilizing Method of Deployable Systems (전개구조시스템의 안정화 방법에 관한 연구)

  • Kim, Seung-Deog;Park, Sun-Kyeong
    • Journal of Korean Association for Spatial Structures
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    • v.14 no.1
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    • pp.93-99
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    • 2014
  • Deployable structure is a system on which the study is being actively performed in various fields including architecture field. However, There is little study which can enhance the practicality since the interpretation condition is difficult as the unstable structure in the architecture field. In this study, the Scissors system has been focused on among the Deployable structure. The structure was developed using the Scissors system and the Mock-up test was performed. Through this, the unfolding method was proposed and the practicability was surveyed through the specific design of the Test model. Also, the structure stability was reviewed through structure analysis of Mock-up test model. and stabilizing method was proposed.

A Study on the characteristics of transferring vibration induced by the operational High-speed Train (고속철도 운행에 의한 진동전달특성에 관한 연구)

  • 배동명;백용진;박상곤;강상중
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2000.04b
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    • pp.340-346
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    • 2000
  • The vibration induced by high speed train running on rail is dealt with as an environmental problem. The train induced vibration is characterized by moving loads of specific frequency contents and soil conditions. In fact various sources are involved the wheal distance, number of cars, speed of operation, drift of rails, structural form vibration, etc. In this paper the characteristics of transferring vibration induced by the operational high-speed train is discussed. And the field measurements was conducted at region from Chungnam Yungi So-jung-myan to Chungbuk Chungwon hyun-do-myun. In the future is would be proposed the fundamental data for establishment of the countermeasure for vibrational reduction of high speed train using the results of the field measurements and quantitative prediction of the vibration level

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Detection of View Reversal in a Stereo Video

  • Son, Ji Deok;Song, Byung Cheol
    • IEIE Transactions on Smart Processing and Computing
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    • v.2 no.5
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    • pp.317-321
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    • 2013
  • This paper proposes a detection algorithm for view reversal in a stereoscopic video using a disparity map and motion vector field. We obtain the disparity map of a stereo image was obtained using a specific stereo matching algorithm and classify the image into the foreground and background. Next, the motion vector field of the image on a block basis was produced using a full search algorithm. Finally, the stereo image was considered to be reversed when the foreground moved toward the background and the covered region was in the foreground. The proposed algorithm achieved a good detection rate when the background was covered sufficiently by its moving foreground.

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Comparison of Quality Metrics of Perspective and Refocused Images in Light Field Images (라이트필드 영상의 Perspective 및 재초점 화질측정방법 비교)

  • Duong, Vinh Van;Nguyen, Thuc Huu;Jeon, Byeungwoo
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2019.11a
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    • pp.228-229
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    • 2019
  • Digital refocusing and perspective change are the most expected applications of light field (LF) images. As LF image has a large amount of data, its compression is very essential. The fidelity of LF image after compression needs to be evaluated differently depending on a specific application such as perspective change or refocusing. In this paper, we investigate the fidelity of images after perspective change and refocusing. Several state-of-the-art objective quality metrics are compared. Our experiment shows that IWPSNR is the most reliable metric for both perspective and focus changes, but it does not outperform the popular metrics such as PSNR and SSIM.

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Field data analyses for repairable products (수리가능한 제품의 사용현장 데이터 분석)

  • 배도선;윤형제;최인수
    • The Korean Journal of Applied Statistics
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    • v.8 no.2
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    • pp.133-145
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    • 1995
  • This paper is concerned with the method of estimating lifetime distribution from field data for repairable products with multiple modes of failure, and is an extension of Bai et al.(1995). The log linear function is considered as a model for describing the relation between failure time of a product and covariates. Using the nonhomogeneous poisson process, general methods for obtaining pseudo maximum likelihood estimators(PMLEs) for the parameters are outlined and specific formulas for Weibull distribution are obtained. Effects of follow-up percentage on the PMLEs are investigated. Extension to case-cohort design is also considered.

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Strategies for the Successful Technology Transfer from Public Research Institutes in Korea (공공연구기관의 기술이전 활성화 전략)

  • Lee, Yoon-Jun
    • Journal of Technology Innovation
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    • v.16 no.1
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    • pp.141-163
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    • 2008
  • Technology transfer from public research institutes is receiving an ever increasing importance in today's fast growing economy. Many factors have been cited as influencing the transfer performance. This study is focused on the strategy of institutes which is characterized by technology strategic factors and organizational/institutional factors. Methodologically, the technology strategy is represented by the information contained in applied patents, and the performance of technology transfer is indicated by the number of licensing contracts and royalty income. To further improve the contribution of public research institutes through technology transfer, I argue that individual institutes become more specialized in specific field and become more open to collaboration. It is also recommended that public research institutes gather together since it is easy to form the consortium of technology licensing office and it is not necessary to be located near the industrial field.

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