• Journal of Korea Multimedia Society
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• v.16 no.2
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• pp.234-240
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• 2013

All around the world, numerous scientists have been carried out researches of e-Science to improve performance of computations and accessibility of their experimental flexibilities for a long times. However, they still have been in difficulty securing high-performance computing facilities. In case of Aerodynamics, for example, a single experiment costs a tremendous amount of budget and requires a span of more than 6 months even though researchers have been developed diverse improved mathematical methods as well as relied on advanced computing technologies to reduce runtime and costs. In this paper, we proposed a multiple infrastructure-based scientific workflow environments for engineering education in fields of design optimization of aircraft and demonstrated the superiority. Since it offers diverse kind of computing resources, it can offer elastic resources regardless of the number of tasks for experiments and limitations of spaces. Also, it can improve education efficiency by using this environment to engineering education.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.28 no.2
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• pp.131-138
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• 2015

In this paper, the modified live-load and designed formula are studied according to the fact the highway bridge design specifications are recently revised. The two examples for composite steel plates and PSC girder bridges are studied. The envelope is analyzed with the finite element models and lateral load distribution method applying the existing highway bridge specification(2010), the newly revised highway bridge specification(2015) and AASHTO LRFD. In case of composite steel plates, length changes between spans are studied, and in case of PSC girder. changes of the number of cross-beams and spans, and span-lengths, are analyzed.

• Korean Journal of Food Science and Technology
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• v.47 no.6
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• pp.687-697
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• 2015

With the shortage of edible fats and oils and depletion of fossil fuels in many countries, microbial lipids is emerging as one of the most promising sources of fats and oils in the global market. Oleaginous microorganisms, also called single cell oils (SCOs), can accumulate lipids more than 25% in the cell volume. Triacylglycerols are the major storage lipids. SCOs offer several advantages for lipid production as follows: SCOs have short life span which would shorten production time, cultivation conditions are not affected by climate and place; the production process is easy to control. There are a number of oleaginous yeasts, molds, and microalgae. Furthermore, the lipid productivity of SCOs can be enhanced through strain improvement and the optimization of cultivation conditions. The new strains developed using recent advanced biotechnical methods showed greatly improved oleaginicity. Further, hydrolysates of lignocellulosic materials can be used as carbon sources for economic production of SCO.

• The Korean Journal of Pharmacology
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• v.17 no.1 s.28
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• pp.41-46
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• 1981

Eighty of Sarcoma 180 bearing mice, averaging 30 gm of body weight, were divided into eight groups of animals receiving Saline as the control, Corynebacterium parvum, Tubercin-3 and Cyclophosphamide alone and Cyclophosphamide combined with C. parvum, with Tubercin-3 and with both C. parvum and Tubercin-3 and Tubercin-3 combined with C. parvum respectively. Treatment was initiated 4.8 hours after tumor implantation and repeated three times once a day. Doses were suspended or dissolved in 0.2 ml of Saline: 1.4 mg of C. parvum: 0.5 micrograms of Tubercin-3; and 2.7 mg of Cyclophosphamide either in alone or in combination. All the agents given were administered subcutaneously but Cyclophosphamide was given intraperitoneally. The observation on the general conditions of animal took place twice a day following the treatment until the time of death after tumor implantation was determined. Average survival days in each group were as follows: In Control, Saline (11.2 days), C. parvum (14.8 days), Tubercin-3 (16.7 days), Cyclophosphamide(18.7 days). In combination therapy, Cyclophosphamide with C. parvum(22.8 days) with Tubercin-3 (26.9 days). Cyclophosphamide with both C. parvum an Tubercin-3, however, was somewhat longer than in Cyclophosphamide alone but shorter than in combined with either one of C. parvum or Tubercin-3. Finally, in combination with immunotherapeutic agents, Tubercin-3 and C. parvum each other it (8.2 days) was shorter even than Control. Life span of host is, in generally, inversely related to the number of malignant cells and conclusively, the therapeutic potentiation was reflected to be extended survival in combined treatment of a chemotherapeutic Cyclophosphamide with either one of immunotherapeutics, Tubercin-3 or C. parvum. Tubercin-3 and C. parvum in combination, however, appeared to be antagonistic each other.

• Molecules and Cells
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• v.23 no.1
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• pp.17-22
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• 2007

We have expressed human erythropoietin (EPO) in transgenic mice using a recombinant EPO cDNA combined with a partial TPO construct. The gene was microinjected using standard techniques and five mice were detected as transgenic by PCR and further used as founders. The life span of the transgenic founders was much shorter than that of their normal littermates. Most of the tissues of the transgenic founders contained human EPO transcripts as judged by RT-PCR. Especially high expression levels were seen in the liver and lung. EPO protein levels in serum were examined by ELISA and ranged from 266-414 mIU/ml. The number of red blood cell, white blood cell and hemoglobin in the hEPO transgenic mice was higher than in normal mice. These results indicate that overexpression of hEPO is deleterious and can provoke lung failure and erythrocytosis.

• Journal of KIISE:Databases
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• v.37 no.5
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• pp.238-249
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• 2010

Flash memory has been studied as a storage medium in order to improve the performance of the system using its high computing speed in the DBMS field where frequent data access is needed. The most difficulty using the flash memory is the performance degradation and the life span shortening of flash memory coming from inefficient in-place update. Log based approaches have been studied to solve inefficient in-place update problem in the DBMS where write operations occur in smaller size of data than page frequently. However the existing log based approaches suffer from the frequent merging operations, which are the principal cause of performance deterioration. Thus is because their fixed log area management can not guarantee a sufficient space for logs. In this paper, we propose non-fixed log area management technique that can minimize the occurrence of the merging operations by promising an enough space for logs. We also suggest the cost calculation model of the optimal log sector number minimizing the system operation cost in a block. In experiment, we show that our non-fixed log area management technique can have the improved performance compared to existing approaches.

• Journal of Astronomy and Space Sciences
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• v.21 no.3
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• pp.221-232
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• 2004

Gauss method for the initial orbit determination was tested using angle-only data obtained by orbit propagation using TLB and SGP4/SDP4 orbit propagation model.. As the analysis of this simulation, a feasible time span between observation time of satellite resulting the minimum error to the true orbit was found. Initial orbit determination is performed using observational data of GPS 26 and Koreasat 2 from 0.6m telescope of KAO(Korea Astronomy Observatory) and precise orbit determination is also performed using simulated data. The result of precise orbit determination shows that the accuracy of resulting orbit is related to the accuracy of the observations and the number of data.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.42 no.7
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• pp.535-543
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• 2014

A computational simulation for a nonslender BWB UCAV configuration with rounded leading edge and span of 1.0m was performed to analyze its aerodynamic characteristics. The freestream is 50m/s over -4 to 26 degree A.o.A.s. Reynolds number based on the mean chord length is $1.25{\times}10^6$. 3D multi block hexahedral grids are used which allow good grid quality and ease to capture boundary layer. ${\gamma}-Re_{\theta}$ model as well as $k-{\omega}$ SST model is employed to assess the effect of transition for flow behavior. Drag and lift of the UCAV were well predicted while $C_M$ is under predicted at high angle of attacks and influenced by the turbulence models strongly. After assessing pressure distribution, skin friction lines and velocity field around the UCAV configuration, it was found that transition effect should be considered to enhance the prediction of aerodynamic behavior by a vortical flowfield.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.36 no.4
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• pp.337-345
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• 2008

this study, three dimensional surface pressure distributions of SWIM whose main wing has NACA4412 airfoil with NACA0012 flaps were experimentally measured by pressure sensitive paint. Surface pressures on suction and pressure sides of the wing were measured by changing an angle of attack at a Reynolds number of 3.1x105 in KARI 1m subsonic wind tunnel. The experimental results showed that as an angle of attack increases minimum pressure region on a suction side moved from the wing root to the tip and low pressure region around trailing edge of the wing tip which causes wing tip vortex was observed. Although low pressure region at the tip still observed at an angle of attack 15 deg., other area on a suction side showed flat pressure distribution in a span-wise direction. It was also observed that the mean value of pressure coefficients was about 0.077 through a comparison between PSP and pressure taps at the same test conditions.

• THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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• v.2 no.1
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• pp.43-56
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• 1996

The sprig of Sojekbojungwhan(消積保中丸) has been used for curing as a traditional medicine without any experimental evidence to support the rational basis for their clinical use. This experiment was carried out to evaluate the possible therapeutic or antitumoral effects of Sojekbojungwhan extract against cancer, and to study some mechanisms responsible for its effect. The cytotoxic and antitumor effects were evaluated on human cell lines(A549, hep3B, Caki-1, Sarcoma 180) after esposure to Sojekbojungwhan extract using in ILS, colony forming efficiency and SRB assay which were regarded as a valuable method for cytotoxic and antitumor effects of unknown compound on tumor cell lines. The results obtained in this studies were as follows. 1. As a result of exposure to Sojekbojungwhan extract, the proliferation of A549, hep3B, Caki-1, good correlations were shown from the results of SRB assay and those of clogenetic assay. 2. The oral administration of Sojekbojungwhan extact showed significant effects of increase of MST(mean survival time) and ILS(increased life span) depending on the increasing concentration. 3. Against squamous cell carcinoma induced by MCA, Sojekbojungwhan decreased not only the frequency of tumor production but also the number and weight of tumors per tumor bearing mice(TBM). Sojekbojungwhan also significantly suppressed the development of 3LL cell-implanted tumors by frequency and their size, and some developed tumors were regressed by the continuous treatment of Sojekbojungwhan extract into TBM. 4. Sojekbojungwhan extract also increased NK cell activities. According to the above results, it could be suggested that Sojekbojungwhan extract has some antitumor effects.