• 한국의학물리학회지:의학물리
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• 제17권3호
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• pp.159-166
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• 2006

기능성 자기공명영상을 이용하여 진동자극에 대한 감각피질의 비선형성에 대하여 연구하였다. 진동자극은 25 Hz의 주파수로 5개의 각기 다른 진동 자극 기간, 2초, 4초, 8초, 12초 그리고 16초와 함께 20초의 무자극 주기와 pseudo-random순서로 구성되었다. 감각피질에 대한 자극 기간의 변화에 따른 선형성을 이해하기 위하여 두 다른 방법(시스템의 선형성 조사법과 gamma-variate 함수를 적용하여 impulse response함수를 구하는 방법)을 사용하여 혈류반응 함수를 분석하였는데, 그 결과는 거의 비슷하였다. 감각피질에서의 BOLD 반응은 8초보다 작은 자극 기간 동안에는 비선형이고 8초 이상일 때는 선형성을 보였다. 자극 기간의 함수로 Impulse response 함수의 진폭, 면적, 피크까지의 시간, FWHM을 계산하였고 진폭과 면적의 크기는 자극 기간이 증가할 때 감소함을 보여줌으로써 자극 기간 8초에서 BOLD 반응이 비선형성에서 선형성으로 변함을 뒷받침해 주었다.

• 한국의학물리학회지:의학물리
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• 제15권3호
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• pp.128-133
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• 2004

기능적 자기공명영상을 이용하여 진동자의 자극에 따른 감각 피질의 반응에 대하여 연구하였다 주로 40 Hz 이하의 주파수에 반응하는 촉각소체의 혈류반응을 조사하기 위하여 8, 15, 그리고 25 Hz의 주파수를 사용하였다. 사용되고 있는 진동자의 한계를 극복한 공기의 압력을 이용하여 진동할 수 있는 진동자를 특수 제작하였다. 예측한 바와 같이 감각 피질의 촉각소체 부위가 주파수에 따라 반응하는 모습을 볼 수 있었다. 주파수 대 반응 면적을 각 pixel의 개수와 signal percent change로 분석하여 주파수가 증가할수록 signal percent change의 분포는 넓어지고 더 많은 pixel들이 반응한다는 것을 알 수 있었다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2004년도 추계학술대회 논문집
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• pp.1303-1306
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• 2004

We developed a symmetrical upper limb motion trainer for chronic hemiparetic subjects. This trainer enabled the practice of a forearm pronatio $n^ination and wrist flexion/extension. In this study, we have used functional magnetic resonance imaging(fMRI) with the developed symmetrical upper limb motion device, to compare brain activation patterns elicited by flexion/extension wrist movements of control and hemiparetic subject group. In control group, contralateral somatosensory cortex(SMC) and bilateral cerebellum were activated by dominant hand movement(Task 1), while bilateral movements by dominant hand(Task 2) activated the SMC in both cerebral hemispheres and ipsilateral cerebellum. However, in hemiparetic subject group, contralateral supplymentary motor area(SMA) was activated by unaffected hand movement(Task 1), while the activation of bilateral movements by unaffected hand(Task 2) showed only SMA in the undamaged hemisphere. This study, demonstrating the ability to accurately measure activation in both sensory and motor cortex, is currently being extended to patients in clinical applications such as the recovery of motor function after stroke.ke.

• 한국정밀공학회지
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• 제22권8호
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• pp.192-198
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• 2005

In this paper, we propose a new training system for the improvement of equilibrium sense using unstable platform. The equilibrium sense, which provides orientation with respect to gravity, is important to integrate the vision, somatosensory and vestibular function to maintain the equilibrium sense of the human body. In order to improve the equilibrium sense, we developed the software program such as a block game, pingpong game using Visual C++. These training system for the equilibrium sense consists of unstable platform, computer interface and software program. The unstable platform was a simple structure of elliptical-type which included tilt sensor, wireless RF module and the device of power supply. To evaluate the effect of balance training, we measured and evaluated the parameters as the moving time to the target, duration to maintain cursor in the target of screen and the error between sine curve and acquired data. As a results, the moving time to the target and duration to maintain cursor in the target was improved through the repeating training of equilibrium sense. It was concluded that this system was reliable in the evaluation of equilibrium sense. This system might be applied to clinical use as an effective balance training system.

• 전자공학회논문지
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• 제51권10호
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• pp.213-220
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• 2014

시공간 분해능이 우수하고 비침습적으로 대뇌 신경활동의 측정이 가능한 뇌자도는 뇌기능 연구 및 뇌질환 진단에 유용한 진단용 의료기기이다. 순수 국내기술로 개발한 한국형 뇌자도 시스템을 임상시설(병원)에 설치하고 뇌질환 환자를 대상으로 유발자계를 측정, 분석하여 한국형 뇌자도 시스템의 임상 응용 가능성을 검토하였다. 1) 반측성 안면 경련 환자를 대상으로 소리자극에 대한 청각유발자계를 측정, 분석하여 안면신경과 청신경의 상호작용 여부 및 이명과의 연관성 검토, 2)뇌종양 환자의 정중신경 자극에 대한 체성감각 유발자계를 측정하여 뇌전증 유무에 따른 연관성 검토. 뇌자도 데이터의 분석 결과로부터 한국형 뇌자도 시스템이 뇌기능 연구 및 뇌질환 진단에 유용한 시공간적인 분석 정보를 제공할 수 있음을 시사하고 있다.

• Journal of Communications and Networks
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• 제18권5호
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• pp.837-845
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• 2016

Providing a customer with tailored location-based services (LBSs) is a fundamental problem. For location-estimation techniques with radio-based measurements, LBS applications are widely available for mobile devices (MDs), such as smartphones, enabling users to run multi-task applications. LBS information not only enables obtaining the current location of an MD but also provides real-time push-pull communication service. For indoor environments, localization technologies based on radio frequency (RF) pattern-matching approaches are accurate and commonly used. However, to survey radio information for pattern-matching approaches, a considerable amount of time and work is spent in indoor environments. Consequently, in order to reduce the system-deployment cost and computing complexity, this article proposes an indoor positioning approach, which involves using Asus Xtion to facilitate capturing RF signals during an offline site survey. The depth information obtained using Asus Xtion is utilized to estimate the locations and predict the received signal strength (RF information) at uncertain locations. The proposed approach effectively reduces not only the time and work costs but also the computing complexity involved in determining the orientation and RF during the online positioning phase by estimating the user's location by using a smartphone. The experimental results demonstrated that more than 78% of time was saved, and the number of samples acquired using the proposed method during the offline phase was twice as much as that acquired using the conventional method. For the online phase, the location estimates have error distances of less than 2.67 m. Therefore, the proposed approach is beneficial for use in various LBS applications.

• 한국초전도ㆍ저온공학회논문지
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• 제17권4호
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• pp.34-37
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• 2015

Developing Magnetoencephalography (MEG) based on Superconducting Quantum Interference Device (SQUID) facilitates to observe the human brain functions in non-invasively and high temporal and high spatial resolution. By using this MEG, we studied alpha rhythm (8-13 Hz) that is one of the most predominant spontaneous rhythm in human brain. The 8-13 Hz rhythm is observed in several sensory region in the brain. In visual related region of occipital, we call to alpha rhythm, and auditory related region of temporal call to tau rhythm, sensorimotor related region of parietal call to mu rhythm. These rhythms are decreased in task related region and increased in task irrelevant regions. This means that these rhythms play a pivotal role of inhibition in task irrelevant region. It may be helpful to attention to the task. In several literature about the alpha-band inhibition in multi-sensory modality experiment, they observed this effect in the occipital and somatosensory region. In this study, we hypothesized that we can also observe the alpha-band inhibition in the auditory cortex, mediated by the tau rhythm. Before that, we first investigated the existence of the alpha and tau rhythm in occipital and temporal region, respectively. To see these rhythms, we applied the visual and auditory stimulation, in turns, suppressed in task relevant regions, respectively.