• The Korean Journal of Physiology and Pharmacology
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• v.21 no.2
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• pp.225-232
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• 2017

We demonstrated the effect of nortriptyline, a tricyclic antidepressant drug and serotonin reuptake inhibitor, on voltage-dependent $K^+$ (Kv) channels in freshly isolated rabbit coronary arterial smooth muscle cells using a whole-cell patch clamp technique. Nortriptyline inhibited Kv currents in a concentration-dependent manner, with an apparent $IC_{50}$ value of $2.86{\pm}0.52{\mu}M$ and a Hill coefficient of $0.77{\pm}0.1$. Although application of nortriptyline did not change the activation curve, nortriptyline shifted the inactivation current toward a more negative potential. Application of train pulses (1 or 2 Hz) did not change the nortriptyline-induced Kv channel inhibition, suggesting that the effects of nortiprtyline were not use-dependent. Preincubation with the Kv1.5 and Kv2.1/2.2 inhibitors, DPO-1 and guangxitoxin did not affect nortriptyline inhibition of Kv channels. From these results, we concluded that nortriptyline inhibited Kv channels in a concentration-dependent and state-independent manner independently of serotonin reuptake.

• 한국방재학회:학술대회논문집
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• 2007.02a
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• pp.133-136
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• 2007

Cross correlation of seismic-background motions (Campillo and Paul, 2003; Shapiro et al., 2005) is applied to observations from the Korean Meteorological Administration seismic network to estimate the short-period Rayleigh and Love wave dispersion characteristics of the region. Standard processing procedures are applied to the cross correlation, except that signal whitening is used in place of one-bit sampling to equalize power in signals from different times. Multiple-filter analysis is used to extract the group velocities from the estimated Green's functions, which are then used to image the spatially varying dispersion at periods between 0.5 and 20 sec. The tomographic inversion technique used inverts all periods simultaneously to provide a smooth dispersion curve as a function of period in addition to the usual smooth spatial image for a given period. The Gyeongsang Basin in the southeastern part of the peninsula is clearly resolved with lower group velocities.

• Journal of the Korean Society of Costume
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• v.24
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• pp.157-176
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• 1995

The purpose of this treatise is to study external form and internal meaning of minimal expression fashion which appeared as a major stream in modern fashion trends to understand one aspect of modernism in fashion and also to gain insight into internal value of human beings through fashion. The results can be summarized as follows : Firstly , minimalism is a trend in art attempting to seek essence of the object by presenting simple and disciplined expressions by minimal formative means and minimal production process. Secondly, minimal expression in fashion means seeking simplicity an dpurity by using minimum design elements and minimal productive process. Thirdly, external from of minimal expression fashion can be created through application of following minimal expression techniques. 1. Minimal expression techniques in terms of line mean smooth curve flowing along body contours, straight lines of diagonal lines into desciplined silhouette or rendering internal contour lines. 2. Minimum expression techniques in terms of forms mean forms of smooth curves flowing along boyd or forms with simple geometric forms from qualitative aspects, In terms of volume it means quest for essence of pure body itself by revealing body as it is by minimizing the size of dress or its area and herein is contained using simple geometric pattern or utilizing textiles without any patterns.3. Minimal expression techniques by colors mean simple colors such as primary colors, colors without clear distinctions or natural colors and in terms of quantity it means quest for one color within one item of dress or combination of each items when getting dressed. 4. Minimal expression techniques in terms of fabrics mean fabrics with simple surfaced. In terms of quantity it means quest for essence of tight fitting thin textiles to human body or using transparent materials to human body thus exposing body contours as it is. 5. Minimal expression techniques in terms of productive process mean minimizing process of tailoring , sewing or ornamenting and seeking for simplicity and purity. 6. Minimal expression techniques in terms of manufacturing process mean selection of technique conveying simple image with disciplined simple image. Fourthly, minimal expression fashion with external expression as mentioned in the above lay body-priority style and its internal meaning can be asummed as quest for essence and purity of human body.

• 한국지구물리탐사학회:학술대회논문집
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• 2006.06a
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• pp.41-50
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• 2006

The crustal structure of Korean Peninsula have been investigated by analyzing group velocity dispersion data of surface wave. Cross.correlation of seismic background motions (Campillo and Paul, 2003; Shapiro et al., 2005) has been applied to estimate the short.period Rayleigh. and Love.wave group velocity dispersion characteristics of the region. Standard processing procedures were applied to the cross.correlation, except that signal whitening was used in place of one.bit sampling equalize power in signals from different times. Multiple.filter analysis was used to extract the group velocities from the estimate Green's functions, which were then use to image the spatially varying dispersion at periods between 0.5 and 20 seconds. The tomographic inversion technique used inverted all periods simultaneously to provide a smooth dispersion curve as a function of period in addition to the usual smooth spatial image for a given period. The Gyeongsang Basin in the southeastern part of the peninsula is clearly resolved with lower group velocities.

• Journal of the Korean Institute of Intelligent Systems
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• v.24 no.1
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• pp.52-57
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• 2014

This paper presents an implementation of a smooth path planning method considering physical limits on a real time operating system for a two-wheel mobile robot. A Bezier curve is utilized to make a smooth path considering a robot's position and direction angle through the defined path. A convolution operator is used to generate the center velocity trajectory to travel the distance of the planned path while satisfying the physical limits. The joint space velocity is computed to drive the two-wheel mobile robot from the center velocity. Trajectory planning, velocity command according to the planned trajectory, and monitoring of encoder data are implemented with a multi-tasking system. And the synchronization of tasks is performed with a real-time mechanism of Event Flag. A real time system with multi-tasks is implemented and the result is compared with a non-real-time system in terms of path tracking to the designed path. The result shows the usefulness of a real-time multi-tasking system to the control system which requires real-time features.

• Journal of the Society of Naval Architects of Korea
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• v.56 no.1
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• pp.82-93
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• 2019

In this paper, the ductile fracture criteria for a marine structural steel (EH36) are presented and validated. The theoretical background of the recently developed Hosford-Coulomb (HC) fracture strain model and the DSSE fracture strain model which was developed to apply to the shell elements is described. In order to accurately estimate the flow stress in the large strain range up to the fracture, the material constants for the combined Swift-Voce constitutive equation were derived by the numerical analyses of the smooth and notched specimens made from the EH36 steel. As a result of applying the Swift-Voce flow stress to the other notched specimen model, a very accurate load - displacement curve could be derived. The material constants of the HC fracture strain and DSSE fracture strain models were independently calibrated based on the numerical analyses for the smooth and notch specimen tests. The user subroutine (VUMAT of Abaqus) was developed to verify the accuracy of the combined HC-DSSE fracture strain model. An asymmetric notch specimen was used as verification model. It was confirmed that the fracture of the asymmetric specimen can be accurately predicted when a very small solid elements are used together with the HC fracture strain model. On the other hand, the combined HC-DSSE fracture strain model can predict accurately the fracture of shell element model while the shell element size effect becomes less sensitive.

• Magazine of the Korean Society of Agricultural Engineers
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• v.10 no.1
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• pp.1394-1408
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• 1968

The tidal discharge is defined as the quantity of water flowing through a certain cross-section per unit of time, in contrast to river discharges, tidal discharges change periodically in magnitude and direction. Thus the total volumes of water flowing into again out of the system-called flood volume and ebb volume, respectively, depend on both the tidal and the river discharges. To ditermine the tidal discharge and the flood and ebb volumes of the Yong-san river, the discharges were measured at spring, mean and neap tide and simultaneous gage reading were taken at Samhak-do, Lower Myo-do, Myongsan-ni and Naju. The general procedure for measuring the tidal discharges was as follows. First, several cross-sections were measured and one of them was chosen. First, several cross-sections were measured and one of them was chosen. Then verticals were serected in the chosen cross section. Because comparatively few verticals should be representative of the discharge distribution over the river profile, the selection was done in accordance with the somtimes irregular bottom profile. The velocities were measured with the same current meters. The observations which included water level readings were continued for a period of about 13 hours. The current direction meter, a pyramid shaped resistance body, suspend in the water on a thin wire. The bubble in a circular tilting level fixed to the wire indicates the direction of the current. Reading were taken at intervals of 1m for depths of 10m or less, and for depths over 10m at intervals of 2m, going downwards and upwards. The averages of the two velocities were used for the computation of the discharges. The discharges and the flood and ebb volumes were ditermined by a graphical method. The mean velocities, corrected for their direction when necesary, were ditermined for each time interval and each vertical, and these velocities were plotted against the time. The resulting curves show possible mistakes very clearly, and the effect of observation errors could be reduced. The corrected velocities read from the curve at half-hour intervals were multiplied by the depth at the virtical at the corresponding time. The discharges thus found were ploted against the position of the vertical in the transit and joined by a smooth curve, integration of the curve rendered the total discharges as they occurred of half-hour intervals. Plotting these total discharges against the time yeilded during the day. The flood and ebb volumes were obtained by integration of the total discharge curve.

• Korean Journal of Food Science and Technology
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• v.24 no.2
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• pp.165-170
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• 1992

The creep behavior of gels made with $30{\sim}45%$ gelatinized rice starch was measured over a wide range of temperature. Compressive creep curves of rice starch gels conformed to a six element mechanical model consisting of one Hookean, two Voigt and one Newtonian component. The creep compliance of gels decreased with increasing starch concentrations. Among viscoelastic constants of the mechanical model, elastic modulus was mainly influenced by the change of starch concentrations. The concentration-invariant compliance curve was obtained by reduction to 38% using reduction parameter $a_{c}$. The creep compliance curves of 45% starch gels increased with temperature, which indicated that rice starch gels became softer and less rigid with increasing temperature. When the compliance at $20^{\circ}C$ was set as a reference curve, creep compliance data for 45% gels at various temperature could be superimposed as a continuous smooth curve. The apparent activation energies of 45% rice starch gels calculated by the modified WLF equation were not intrinsic, but decreased as temperature increased.

• Geomechanics and Engineering
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• v.7 no.5
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• pp.569-587
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• 2014

Triaxial compression creep tests were performed on salt rock samples using cyclic confining pressure with a static axial pressure. The test results show that, up to a certain time, changes in the confining pressure have little influence on creep properties of salt rock, and the axial creep curve is smooth. After this point, the axial creep curve clearly fluctuates with the confining pressure, and is approximately a straight line both when the confining pressure decreases and when it increases within one cycle period. The slope of these lines differs: it is greater when the confining pressure decreases than when it increases. In accordance with rheology model theory, axial creep equations were deduced for Maxwell and Kelvin models under cyclic loading. These were combined to establish an axial creep equation for the Burgers model. We supposed that damage evolution follows an exponential law during creep process and replaced the apparent stress in creep equation for the Burgers model with the effective stress, the axial creep damage equation for the Burgers model was obtained. The model suitability was verified using creep test results for salt rock. The fitting curves are in excellent agreement with the test curves, so the proposed model can well reflect the creep behavior of salt rock under low-frequency cyclic loading. In particular, it reflects the fluctuations in creep deformation and creep rate as the confining pressure increasing and decreasing under different cycle periods.

• Transactions of the Korean Society of Automotive Engineers
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• v.1 no.1
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• pp.131-139
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• 1993

Low cycle fatigue characteristics of cast aluminum alloy A356 with a yield strength and ultimate strength of 229 and 283 MPa respectively was evaluated using smooth axial specimen under strain controlled condition. Reversals to failure ranged from 16 to 107. The cast aluminum alloy exhibited cyclically strain-gardening behavior. The results of low cycle fatigue tests indicated that the conventional low cycle fatigue tests indicated that the conventional low cycle fatigue life model was not a satisfactory representation of the data. This occurred because the elastic strain-life curve was not-log-log linear and this phenomena caused a nonconservative and unsafe fatigue life prediction at both extremes of long and short lives. A linear log-log total strain-life model and a bilinear log-log elastic strain-life model were proposed in order to improve the representation of data compared to the conventional low cycle fatigue life model. Both proposed fatigue life models were statistically analyzed using F tests and successfully satisfied. However, the low cycle fatigue life model generated by the bilinear log-log elastic strain-life equation yielded a discontinuous curve with nonconservatism in the region of discontinuity. Among the models examined, the linear log-log total strain-life model provided the best representation of the low cycle fatigue data. Low cycle fatigue life prediction method based on the local strain approach could conveniently incorporated both proposed fatigue life models.