• Korean Journal of Veterinary Research
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• v.33 no.4
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• pp.617-622
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• 1993

The preliminary studies on the localization of adrenoceptors were performed on smooth muscle strips of bovine esophageal groove. The mechanical activity of the muscle strip was recorded isometrically in vitro.w In the bottom circular muscle strips. the excitatory ${\alpha}-adrenergic$ responses were not blocked by tetrodotoxin$(2.1{\times}10^{-6}M)$ and denervation which was carried by cold storage of strips for 48 hrs in Tyrode's solution at $5-6{^{\circ}C}$ without oxygen supply. These excitatory ${\alpha}-adrenergic$ responses were partially blocked by atropine. In the lip longitudinal muscle strips, the inhibitory${\beta}-adrenergic$ responses were not blocked by pretreatment of tetrodotoxin and atropine. The results suggest that ${\beta}-adrenergic$ receptors mediating relaxations are located on the postsynaptic smooth muscle cells, whereas ${\beta}-adrenergic$ receptors mediating contractions are located both in the smooth muscle cells and in the cholinergic neurones.

• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.1
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• pp.203-211
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• 1994

An experiment was carried out to evaluate the heat transfer and pressure drop performances of the smooth tube and two augmented tubes using R-113 under horizontal condensation condition. The augmented tubes are a spirally-twisted tube and an internally-finned tube. The test tube is 13.88 mm in diameter and 3.2 m long. Five different inlet pressure of 0.13, 0.16, 0.18, 0.21 and 0.23 MPa were employed and the mass flux was varied from 80 to 265 $kg/m^{2}s.$ The results showed that the overall heat transfer coefficient for the spirally-twisted tube and internally-finned tube were enhanced by 30-85% and 130-180%, respectively, over that for the smooth tube. The increase in total pressure drop for the spirally-twisted tube and internally-finned tube were reached up to 250-350% and 1100-1600%, respectively, over that for the smooth tube. Correlations were proposed for predicting the condensation heat transfer coefficient for the smooth tube and two augmented tubes.

• Design & Manufacturing
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• v.13 no.3
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• pp.19-23
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• 2019

In the mold industry, CAM software has been introduced to solve the impossible or time-consuming part of the mold industry because the increase in labor costs, the drop in mold price, and the short delivery time are tasks to be solved not only in the manufacturing industry but also in the mold industry as a whole. In order to reduce the processing time and improve the surface roughness, we have been conducting various researches for efficient machining. This study was carried out to compare the ball end mill and radius end mill tools with the Power mill software and NC brain software under the same conditions and to find out the most efficient method of machining the smooth drafting surface and improving the surface roughness. (1) By machining the smooth drafting surface using radius end mill, the machining time is 23.7% faster than when using ball end mill. (2) Surface roughness when machined with radius end mill is smoother than when using ball end mill. Based on these results, it can not be applied to all shapes, but if it is a relatively wide and simple gradient shape, the raster machining method using radius end mill can be more effective in terms of delivery and quality than machining with ball end mill.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.21 no.4
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• pp.243-251
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• 2009

Refrigerant mixtures provide an opportunity to adjust their properties to fit design criteria and a possibility to create new blends that can improve heat transfer characteristics. Therefore, mixture of $CO_2$ and propane is chosen which may be a promising refrigerant and has good environmental compatibility. This paper presents measured heat transfer coefficient data during evaporation process of $CO_2$/propane mixtures flowing upward in vertical smooth and. micro-fin tubes. Smooth and micro-fin tubes with outer diameters of 5 mm and length of 1.44in were selected as test tubes. The tests were conducted at mass fluxes of 212 to $656kg/m^{2}s$, inlet temperatures of -10 to $30^{\circ}C$, heat fluxes of 15 to $60\;kW/m^2$ and for several compositions (75/25, 50/50, 25/75 wt%). Among $CO_2$/propane refrigerant mixtures, the heat transfer characteristics are much better than that of any compositions when the composition is 75/25 (wt%).

• Journal of Pharmacopuncture
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• v.22 no.3
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• pp.122-130
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• 2019

Objectives: The medicinal plants are believed to enhance the natural resistance of the body to infections. Some of the main constituents of the plant and derived materials such as, proteins, lectins and polysaccharides have anti-inflammatory effects. Portulaca oleracea (P. oleracea) were used traditionally for dietary, food additive, spice and various medicinal purposes. This review article is focus on the anti-asthmatic effects of P. oleracea and its constituents. Methods: Various databases, such as the PubMed, Scopus, and Google Scholar, were searched the keywords including "Portulaca oleracea", "Quercetin", "Anti-inflammatory", "Antioxidant", "Cytokines", "Smooth muscle ", and " Relaxant effects " until the end of Jul 2018. Results: P. oleracea extracts and its constituents increased $IFN-{\gamma}$, IL-2, $IFN{\gamma}/IL-4$ and IL- 10/IL-4 ratio, but decreased secretion of $TNF-{\alpha}$, IL-4 and chemokines in both in vitro and in vivo studies. P. oleracea extracts and quercetin also signifcantly decreased production of NO, stimulated ${\beta}$-adrenoceptor and/or blocking muscarinic receptors in tracheal smooth muscles. Conclusion: P. oleracea extracts and quercetin showed relatively potent anti-asthmatic effects due to decreased production of NO, inflammatory cytokines and chemokines, reduced oxidant while enhanced antioxidant markers, and also showed potent relaxant effects on tracheal smooth muscles via stimulatory on ${\beta}$-adrenoceptor or/and blocking muscarinic receptors.

• The Journal of Asian Finance, Economics and Business
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• v.9 no.10
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• pp.1-13
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• 2022

This paper empirically explores the predicting ability of the newly proposed smooth transition (ST) time-varying combining forecast methods. The proposed method allows the "weight" of combining forecasts to change gradually over time through its unique feature of transition variables. Stock market returns from 7 countries were applied to Ad Hoc models, the well-known Generalized Autoregressive Conditional Heteroskedasticity (GARCH) family models, and the Smooth Transition Exponential Smoothing (STES) models. Of the individual models, GJRGARCH and STES-E&AE emerged as the best models and thereby were chosen for constructing the combined forecast models where a total of nine ST combining methods were developed. The robustness of the ST combining forecasts is also validated by the Diebold-Mariano (DM) test. The post-sample forecasting performance shows that ST combining forecast methods outperformed all the individual models and fixed weight combining models. This study contributes in two ways: 1) the ST combining methods statistically outperformed all the individual forecast methods and the existing traditional combining methods using simple averaging and Bates & Granger method. 2) trading volume as a transition variable in ST methods was superior to other individual models as well as the ST models with single sign or size of past shocks as transition variables.

• Archives of Plastic Surgery
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• v.50 no.2
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• pp.160-165
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• 2023

Background The number of cosmetic and reconstructive surgeries that use breast implants is increasing in Korea. Recently, it has been reported that breast implant-associated anaplastic large-cell lymphoma is related to textured breast implants, and interest in classification according to the texture of breast implants is increasing. However, there is currently no clear and unified classification. In particular, the definition of "microtextured" is highly varied. In this study, we retrospectively investigated and analyzed the clinical outcomes of smooth and microtextured breast implants. Methods A retrospective chart review of all patients who underwent breast augmentation surgery with smooth and microtextured silicone gel implants between January 2016 and July 2020 was performed. We retrospectively analyzed implant manufacturer, age, body mass index (BMI), smoking status, incision location, implant size, follow-up period, complications, and reoperation rate. Results A total of 266 patients underwent breast augmentation surgery, of which 181 used smooth silicone gel implants and 85 used microtextured silicone gel implants. Age, BMI, smoking status, implant size, and follow-up period were not significantly different between the two groups. Similarly, complications and reoperation rates were not significantly different between the two groups. Conclusion It is important to provide information regarding the clinical risks and benefits of breast implants to surgeons and patients through a clear and unified classification according to the texture of the breast implant.

• Journal of the Korea Society of Computer and Information
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• v.14 no.6
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• pp.59-64
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• 2009

Edge detection always influenced by the noise of original image, therefore need some methods to eliminate them in advance, and the Mean Shift algorithm has the smooth function which suit for this purpose, so adopt it to fade out the unimportant information and the sensitive noise portions. Above all, we use the Canny algorithm to pick up the contour of the objects we focus on. And, take tests and get better result than the former sole Canny algorithm. This combination method of Mean Shift algorithm and Canny algorithm is suitable for the edge detection processing.

• Korean Journal of Biological Psychiatry
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• v.6 no.1
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• pp.119-124
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• 1999

This study was done to examine whether cigarette smoking improved smooth pursuit eye movement(SPEM) abnormalities in chronic schizophrenic inpatients. Fifteen schizophrenic and twelve alcoholic subjects abstained from their usual cigarette smoking for a minimum of nine hours and their baseline performances during the constant velocity smooth pursuit tasks were assessed. Then, the subjects smoked as much as they desired in a 10 minutes period and were retested immediately after smoking and 15 minutes after smoking. Electrooculographic recordings during the eye movements were converted and saved as digitized files. Power spectral density curves and natural logarithm value of signal/noise(Ln S/N) ratios were computed from them. In the schizophrenic patients, Ln S/N ratios increased significantly immediately after smoking compared to baseline. But, Ln S/N ratios showed no statistically significant changes after 15 minutes compared to baseline. In alcoholic subjects, Ln S/N ratios showed no statistically significant changes immediately after smoking and after 15 minutes compared to baseline. In conclusion, SPEM was improved in schizophrenic patients immediately after smoking and we hypothesized that nicotinic receptor dysfunction maybe a candidate mechanism for smooth pursuit eye movement abnormalities in schizophrenia.

• Journal of Korean Neurosurgical Society
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• v.38 no.5
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• pp.375-379
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• 2005

Objective : Papaverine has been used in treating vasospasm following subarachnoid hemorrhage[SAH]. However, its action mechanism for cerebral vascular relaxation is not clear. Potassium channels are closely related to the contraction and relaxation of cerebral smooth muscle. Therefore, to identify the role of potassium and calcium channels in papaverine-induced vascular relaxation, we examine the effect of papaverine on potassium channels in freshly isolated smooth muscle cells from rat basilar artery. Methods : The isolation of rat basilar smooth muscle cells was performed by special techniques. The whole cell currents were recorded by whole cell patch clamp technique in freshly isolated smooth muscle cells from rat basilar artery. Papaverine was added to the bath solution. Results : Papaverine of $100{\mu}M$ into bath solution increased the amplitude of the outward $K^+$ current which was completely blocked by BKCa[large conductance calcium dependent potassium channels]blocker, IBX[iberiotoxin], and calcium chealator, BAPTA[l,2-bis[o-aminophenoxy]ethane-N,N,N',N'-tetraacetic acid], in whole cell mode. Conclusion : These results strongly suggest that potassium channels may play roles in papaverine-induced vascular relaxation in rat basilar artery.