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Studies on the Efficacy of Combined Preparation of Crude Drug (XXV) -Effects of Soeuminsowhapwon on Anticonvulsion, Analgesic, Antipyretic, Sedative, Isolated Ileum, Blood Vessels and Blood Pressure- (생약(生藥) 복합제제(複合製劑)의 약효(藥效) 연구(硏究)(제25보)(第25報) -소음인소합원(小陰人蘇合元)이 항경련(抗痙攣), 진통(鎭痛), 해열(解熱), 진정(鎭靜), 적출장관(摘出腸管), 혈관(血管) 및 혈압(血壓)에 미치는 영향(影響)-)

  • Jun, Jin-Sang;Kim, Nam-Jae;Won, Do-Hee;Song, Il-Byung;Hong, Nam-Doo
    • Korean Journal of Pharmacognosy
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    • v.16 no.4
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    • pp.199-205
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    • 1985
  • In order to investigate experimentally the clinical effects of Soeuminsohapwon that was prescribed to cure cerebral hemorrhage, palpitation etc, the author tested various activities of extract from the Soeuminsohapwhangwon by the method prescribed in the experimental part. The results of the studies were summarized as follows: Suppressive action was not shown on the convulsion induced by strychnine, but significant effect was noted on the convulsion induced by picrotoxin and caffeine. In acetic acid method, analgesic effect was noted. A prolongation of anesthetic time by pentobarbital sodium and antipyretic effect was observed. Relaxing action was noted on the ileum of mice, also same effect was recognized on contraction of the ileum due to acetylcholine, barium chloride and histamine. The expansion of blood vessels by relaxation of smooth muscle and hypotensive action were noted. According to the above results, effects based on oriental medical references were approximate to the actual experimental results.

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A Study on Vibration Characteristic of Thin Plate in Crack Propagation by Laser Holography Method (Laser Holography 기법에 의한 균열 박판의 결함 진전에 따른 진동 특성에 관한 연구)

  • Kim, In-Gwon;Kim, Koung-Suk;Yoon, Sung-Un;Kang, Ki-Soo
    • Journal of the Korean Society for Precision Engineering
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    • v.17 no.10
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    • pp.200-205
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    • 2000
  • This paper presents the vibration characteristics of a rectangular plate with 45$^{\circ}$oblique crack and a smooth plate subjected to a uniaxial tension. The experiment is adopted by the time-average holography method. The natural frequency and mode shape are considered accurate according to the increasement of tensile load in the study. When tensile load is zero, the vibration modes are almost agreed with the smooth and the 45$^{\circ}$obliquely cracked plate. But since then, according to the increasement of load, it is shown that vibration modes are extremely varied. The effects of the crack length in the vibration characteristic are discussed in detail. It is indicated that the increase of the crack length makes the variation of the frequencies and modes complicate in the range of even a small load.

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Observations of a endometrial stromal sarcoma in the rat uterus wall (Rat의 자궁벽에 발생된 stromal sarcoma의 관찰)

  • Kwak, Soo-dong;Kim, Chong-sup
    • Korean Journal of Veterinary Research
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    • v.34 no.3
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    • pp.435-439
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    • 1994
  • The present observation was focussed mainly on the histopathological and immunohistochemical finding of the tumor developing from the outside of rat uterus wall. In gross finding, this tumor were a oval form mass and 0.75cm and 1cm in greatest demension. The sectioned surface showed uniform, solid, gray-white. In histopathological finding, the tumor showed the form of lymphoid nodule-like structure and was composed of the cells with karryorrhexis, karyolysis and necrosis in the central zone, mature cells in the paracentral zone, and concentric layers of compressed, flattened and atrophied smooth muscle fibers by the proliferating of the cells closely resembling endometrial stromal ells in the peripheral zone and a few smaller nodule-like structure in certain areas of the peripheral zone. In immunohistochemical observations, the proliferating cells presents only among the concentric layers of the smooth muscle fibers in the peripheral zone. Labeling index of proliferating cells in the peripheral zone was $4.34{\pm}1.28%$. These tumor cells did not metastasized in another orgns and labeling index was low, So it was concluded that this tumor was benign stomal sarcoma.

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Friction Factor of Rectangular Open Channel Flow (사각형 개수로 마찰계수)

  • 유동훈
    • Water for future
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    • v.28 no.2
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    • pp.155-168
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    • 1995
  • The present paper discusses the traditional empirical equations of friction factor or cross-sectional mean velocity of open channel flow and suggests the new form of friction factor equation. Dimensional analysis is conducted for the possible forms of traditional empirical equations in order to satisfy the dimensional equality, and new forms of empirical equations are presented with introducing equivalent roughness height. Considering the distribution of friction factor against Reynolds number which has a similar characteristics to that of smooth turbulent flow in circular pipe, the friction factor equation of rectangular open channel flow is developed by modifying the friction factor equation of circular pipe flow for the region of smooth turbulent flow. The equations including the dimensionally-corrected empirical equations are tested against Bazin's laboratory experiments.

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Au Experimental Study on the Aerodynamic Noise by a Circular Jet Impinging on a Plate (평판에 충돌하는 원형분류의 공력소음에 관한 실험적 연구)

  • 이동훈;권영필;한희갑
    • Journal of KSNVE
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    • v.7 no.1
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    • pp.71-79
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    • 1997
  • The objective of this study is to investigate experimentally the effect of surface conditions of the plate on the impinging jet noise. The experimental results about the spectrum, the sound pressure level and the directivity are pressented and discussed in relation with the surface conditions. Regardless of the surface conditions, the pure tones of high level are generated at the same frequency band and the overall sound power level of impinging jets is much higher than that of the free jet. However, the velocity dependence of the sound pressure level and the directivity are different between smooth surfaces and rough surfaces. The dependence of sound pressure level on the jet velocity shows that the smooth surface generates quadrupole-type sound like free jets. However, the perforated or the rough surface radiates sound power exactly proportional to the sixth power of the jet velocity, indicating that the source is fixed dipole type. The directivities of 1/3 octave band sound pressure level for both the free and impinging jet show the peak directivity at 115$^\circ$ upstream, probably due to the refraction associated with velocity gradient.

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A Study on the Shear Behavior of Sands on the Geomembranes (지오멤브레인 상의 모래의 전단거동에 관한 연구)

  • 이석원
    • Journal of the Korean Geotechnical Society
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    • v.16 no.3
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    • pp.89-89
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    • 2000
  • The shear behavior of any interface is a function of the fundamental properties of both materials at the interface. This study aimed at investigating the effect of planar surface roughness on the stress-horizontal displacement curve at theinterfaces composed of various geomembrane textures and granular materials. In addition, the extent of surfacialscarring on smooth geomembranes against granular materials during shearing induced by plowing effect was studied. It wasobserved that the displacements required to achieve peak and residual interface resistance, and the stress-displacementcurve at the interface vary greatly with the surface roughness of geomembrane. Quantification of surface roughnessvariations on smooth geomembrane due to plowing effect showed that the surfacial scarring during shearing by the soilparticles is directly related to both the normal stress and the angularity of the soil particles at the interface. The findingsof this study can be used to provide the useful information for the design and selection of counterface materials.

The Inhibitory Effect of Eupatilin on the Intestinal Contraction Induced by Carbachol

  • Je, Hyun-Dong;Lee, Jong-Min;La, Hyen-Oh
    • Biomolecules & Therapeutics
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    • v.18 no.4
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    • pp.442-447
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    • 2010
  • This study was conducted to determine whether treatment with the anti-inflammatory eupatilin influences intestinal smooth muscle contraction stimulated by carbachol and, if so, to investigate the related mechanism. Denuded ileal or colonic muscles from Sprague-Dawley rats were used for the study and measurements of isometric contractions were obtained using a computerized data acquisition system; this data was also combined with results from molecular experiments. Eupatilin from Artemisia asiatica Nakai significantly decreased carbachol-induced contractions in both ileal and colonic muscles. Interestingly, eupatilin decreased carbachol-induced phosphorylation of ERK1/2 more significantly than that of MYPT1 at Thr855 in ileal and colonic muscles. However, eupatilin significantly decreased phosphorylation of MYPT1 at Thr855, but only in ileal muscle. Therefore, thin filament regulation, including MEK inactivation and related phospho-ERK1/2 decrease, is mainly involved in the eupatilin-induced decrease of intestinal contraction induced by carbachol. In conclusion, this study provides the evidence and a possible related mechanism concerning the inhibitory effect of the flavonoid as an antispasmodic on the agonist-induced contractions in rat ileum and colonic muscles.

Establishment of Collaborative Decision Making Support Process in Pre-Final Design Step (건축 중간설계단계의 협력 의사결정 지원 프로세스 구축)

  • Oh Seung-Jun;Kwon Won;Kim kyung-Sik;Chun Jae-Youl
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • autumn
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    • pp.315-318
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    • 2003
  • In Korea construction project case, architectural construction project is curtailed production because information network process within multidisciplinary isn't smooth. Particularly, the construction is not insufficient about performance, cost and material, construction process, etc. in result various question arises because of design error in construction step. And various mistake is made because communication path within multidisciplinary isn't smooth in architectural design and design change process. Therefore The final object of this study is to propose the establishment method of decision support process for the cooperative design in order to provides improved design coordination and optimize the building system.

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An embedded vision system based on an analog VLSI Optical Flow vision sensor

  • Becanovic, Vlatako;Matsuo, Takayuki;Stocker, Alan A.
    • Proceedings of the Korea Society of Information Technology Applications Conference
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    • 2005.11a
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    • pp.285-288
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    • 2005
  • We propose a novel programmable miniature vision module based on a custom designed analog VLSI (aVLSI) chip. The vision module consists of the optical flow vision sensor embedded with commercial off-the-shelves digital hardware; in our case is the Intel XScale PXA270 processor enforced with a programmable gate array device. The aVLSI sensor provides gray-scale imager data as well as smooth optical flow estimates, thus each pixel gives a triplet of information that can be continuously read out as three independent images. The particular computational architecture of the custom designed sensor, which is fully parallel and also analog, allows for efficient real-time estimations of the smooth optical flow. The Intel XScale PXA270 controls the sensor read-out and furthermore allows, together with the programmable gate array, for additional higher level processing of the intensity image and optical flow data. It also provides the necessary standard interface such that the module can be easily programmed and integrated into different vision systems, or even form a complete stand-alone vision system itself. The low power consumption, small size and flexible interface of the proposed vision module suggests that it could be particularly well suited as a vision system in an autonomous robotics platform and especially well suited for educational projects in the robotic sciences.

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Maximizing the Overall Satisfaction Degree of all Participants in the Market Using Real Code-based Genetic Algorithm by Optimally Locating and Sizing the Thyristor-Controlled Series Capacitor

  • Nabavi, Seyed M.H.;Hajforoosh, Somayeh;Hajforoosh, Sajad;Karimi, Ali;Khafafi, Kamran
    • Journal of Electrical Engineering and Technology
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    • v.6 no.4
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    • pp.493-504
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    • 2011
  • The present paper presents a genetic algorithm (GA) to maximize social welfare and perform congestion management by optimally placing and sizing one Thyristor-Controlled Series Capacitor (TCSC) device in a double-sided auction market. Simulation results, with line flow constraints before and after the compensation, are compared through the Sequential Quadratic Programming SQP method, and are used to analyze the effect of TCSC on the congestion levels of modified IEEE 14-bus and 30-bus test systems. Quadratic, smooth and nonsmooth (with sine components due to valve point loading effect) generator cost curves, and quadratic smooth consumer benefit functions are considered. The main aims of the present study are the inclusion of customer benefit in the social welfare maximization and congestion management objective function, the consideration of nonsmooth generator characteristics, and the optimal locating and sizing of the TCSC using real code-based GA to guarantee fast convergence to the best solution.