• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.21 no.5
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• pp.830-835
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• 2012

A research for application of LDSMC(Low Density Sheet Molding Compound) composite is in progress for lightening the weight. This paper has performed fatigue test and simulation of external panel for Korean commercial vehicle. Before the fatigue test, static test was carried out. From the test, the structural safety was investigated using Goodman diagram. After the static test performance, the fatigue test was conducted at a range of load frequency 5Hz, a stress ratio(R) of 0.05 and an endurance limit of $10^6$ to obtain the S-N curve. The S-N curve is applied to the fatigue analysis of the external panel assembly. The result of FEM analysis was in accord with the experimental result within 83% confidence. It showed that the process to set up the safety range of allowable error is required in process of the design and simulation verification.

• Journal of the Korean Institute of Gas
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• v.19 no.5
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• pp.81-86
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• 2015

A deterministic stress-based methodology has traditionally been applied in pipeline design. Meanwhile, reliability based design and assessment (RBDA) methodology has been extensively applied in offshore or nuclear structures. Lately, the release of ISO standard on reliability based limit state methods for pipelines ISO16708 indicates that the RBDA methodology is one of the newest directions of natural gas pipeline design method. This paper presents a case study of the RBDA procedure for predicting the time-dependent failure probability of pipelines with corrosion defects, where separable Monte Carlo (SMC) method is applied in the reliability estimation for corroded pipeline instead of traditional, crude Monte Carlo(CMC) Method. The result shows the SMC method take advantage of improving accuracy in reliability calculation.

• Journal of the Korean institute of surface engineering
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• v.57 no.2
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• pp.105-114
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• 2024

Tempering behavior and mechanical properties in AISI H13 steel, quenched and tempered from 300 ℃ to 700 ℃ for different tempering time (1, 2, 5, 10, 20 hr) were quantitatively investigated by scanning electron microscopy (SEM), x-ray diffractometer (XRD), impact test machine, rockwell apparatus, ball-on-disk tester. Under the condition that the tempering time is 2 hours, the hardness increases slightly as the tempering temperature increases, but decreases rapidly when the tempering temperature exceeds 500 ℃, while the impact energy increases in proportion to the tempering temperature. Friction tests were conducted in dry condition with a load of 30 N, and the friction coefficient and wear rate according to tempering conditions were measured to prove the correlation with hardness and microstructure. In addition, primary tempering from 300 ℃ to 700 ℃ was performed at various times to establish a kinetic model to predict hardness under specific tempering conditions.

• The Korean Journal of Physiology and Pharmacology
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• v.5 no.3
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• pp.271-278
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• 2001

Oxidative stress and methylglyoxal (MG), a reactive dicarbonyl metabolites produced by enzymatic and non-enzymatic reaction of normal metabolism, induced aldose reductase (AR) expression in rat aortic smooth muscle cells (SMC). AR expression was induced in a time-dependent manner and reached at a maximum of 4.5-fold in 12 h of MG treatment. This effect of MG was completely abolished by cyclohemide and actinomycin D treatment suggesting AR was synthesized by de novo pathway. Pretreatment of the SMC with N-acetyl-L-cysteine significantly down-regulated the MG-induced AR mRNA. Furthermore, DL-Buthionine-(S,R)-sulfoximine, a reagent which depletes intracellular glutathione levels, increased the levels of MG-induced AR mRNA. These results indicated that MG induces AR mRNA by increasing the intracellular peroxide levels. Aminoguanidine, a scanvenger of dicarbonyl, significantly down-regulated the MG-induced AR mRNA. In addition, the inhibition of AR activities with statil, an AR inhibitor, enhanced the cytotoxic effect of MG on SMC under normal glucose, suggesting a protective role of AR against MG-induced cell damages. These results imply that the induction of AR by MG may contribute to an important cellular detoxification of reactive aldehyde compounds generated under oxidative stress in extrahepatic tissues.

• Clinics in Shoulder and Elbow
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• v.22 no.1
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• pp.24-28
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• 2019

Background: Glenoid baseplate location is important to good clinical outcomes of reverse total shoulder arthroplasty (RTSA). The glenoid vault is the determining factor for glenoid baseplate location, but, to date, there are no reports on the effect of central cage location within the glenoid vault on RTSA outcomes when using the $Exactech^{(R)}$ $Equinoxe^{(R)}$ Reverse System. The purpose of this study was to determine the appropriate cage location in relation to the glenoid vault and monitor for vault and/or cortex penetration by the cage. Methods: Data were retrospectively collected from the Samsung Medical Center (SMC) and Seoul National University Bundang Hospital (SNUBH). Patients who underwent RTSA between November 2016 and February 2018 were enrolled. Glenoid vault depth, central cage location within the vault were examined. Inferior glenoid rim-center distance, inferior glenoid rim-cage distance, and center-cage center distances were collected. Results: Twenty-two patients were enrolled. Three SNUBH patients had inappropriate central cage fixation (33.3%) versus 4 SMC patients (30.8%). All cage exposures were superior and posterior to the glenoid vault. Mean center-cage distance was 5.0 mm in the SNUBH group and 5.21 mm in the SMC group. Center-prosthesis distance was significantly longer in the inappropriate fixation group than in the appropriate fixation group (p<0.024). Conclusions: To ensure appropriate glenoid baseplate fixation within the glenoid vault, especially in a small glenoid, the surgeon should place the cage lower than usually targeted, and it should overhang the inferior glenoid rim.

• Proceedings of the Microbiological Society of Korea Conference
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• 2002.10a
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• pp.219.2-219.2
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• 2002

• Journal of the Korean Ceramic Society
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• v.56 no.6
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• pp.583-588
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• 2019

Silicon carbide (SiC) fiber mats generate large amounts of heat through microwave interactions and are used as heating elements in rapid heat treatment furnaces. However, SiC fibers cool immediately when the microwave power is turned off. Therefore, ceramic layers are inserted between the SiC fiber layers to improve the heat conservation performance of SiC fiber mats. In this study, we fabricated SiC fiber mat composites (SMCs) with ceramic layers under various pressures. The SMC fabricated under 0.007 kPa showed the lowest heat-generating temperature and deviation because less necking was observed between the materials. On the other hand, the SMC fabricated under 0.375 kPa showed the highest heat-generating temperature of 1532.33℃. The SMCs prepared in this study using ceramic powder not only showed heat-generating temperatures comparable to those of conventional SiC fiber mats but also exhibited excellent heat-preserving ability.

• Journal of Energy Engineering
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• v.26 no.4
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• pp.84-91
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• 2017

Fiber reinforced plastic (FRP) is a typical plastic composite which is fabricated using fiber reinforcement with resin to represent the high strength properties. The mechanical properties of FRP should be determined by a fibrous material, and the studies about the role of fiber as a reinforcement has been an interested subject, whereas a study along the effect of filler is not so big. However, the filler effect must be considered on the properties of the composite, because the filler influence on the plastic or resin compound which reacts as a matrix material of the composite. Thus, in this work, we studied the filler effect with size and content using $3-6{\mu}m$ of ground calcium carbonate. The specimen was prepared by sheet molding compound (SMC) method, and the mechanical properties were compared with bending strength and tensile strength. As a result, it was confirmed that the size and contents of calcium carbonate affected the strength of composites, and the condition of $2.8{\mu}m$ which was the smallest size condition showed the highest strength.

• Parasites, Hosts and Diseases
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• v.61 no.4
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• pp.455-462
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• 2023

Since 2015, countries in the Sahel region have implemented large-scale seasonal malaria chemoprevention (SMC). However, the mass use of sulfadoxine-pyrimethamine (SP) plus amodiaquine impacts the genetic diversity of malaria parasites and their sensitivity to antimalarials. This study aimed to describe and compare the genetic diversity and SP resistance of Plasmodium falciparum strains in Mali and Niger. We collected 400 blood samples in Mali and Niger from children aged 3-59 months suspected of malaria. Of them, 201 tested positive (Niger, 111, 55.2%; Mali, 90, 44.8%). Polymorphism of merozoite surface protein 1 (msp1) genetic marker showed 201 allotypes. The frequency of the RO33 allotype was significantly higher in Niger (63.6%) than in Mali (39.3%). There was no significant difference in the frequency of the K1 and MAD20 allotypes between the 2 countries. The multiplicity of infection was 2 allotypes per patient in Mali and one allotype per patient in Niger. The prevalence of strains with the triple mutants Pfdhfr51I/Pfdhfr59R/Pfdhps436A/F/H and Pfdhfr51I/Pfdhfr59R/Pfdhps437G was 18.1% and 30.2%, respectively, and 7.7% carried the quadruple mutant Pfdhfr51I/Pfdhfr59R/Pfdhps436A/F/H/Pfdhps437G. Despite the significant genetic diversity of parasite populations, the level of SP resistance was comparable between Mali and Niger. The frequency of mutations conferring resistance to SP still allows its effective use in intermittent preventive treatment in pregnant women and in SMC.

• The Journal of Korean Society for Radiation Therapy
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• v.31 no.2
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• pp.13-24
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• 2019

Purpose: CT scan range is insufficient for various reasons in head and neck Tomotherapy^®. To solve that problem, Re-CT simulation is good because CT scan range affects accurate dose calculations, but there are problems such as increased exposure dose, inconvenience, and a change in treatment schedule. We would like to evaluate the minimum CT scan range required by changing the plan setup parameter of the existing CT scan range. Materials and methods: CT Simulator(Discovery CT590 RT, GE, USA) and In House Head & Neck Phantom are used, CT image was acquired by increasing the image range from 0.25cm to 3.0cm at the end of the target. The target and normal organs were registered in the Head & Neck Phantom and the treatment plan was designed using ACCURAY Precision^®. Prescription doses are Daily 2.2Gy, 27 Fxs, Total Dose 59.4Gy. Target is designed to 95%~107% of prescription dose and normal organ dose is designed according to SMC Protocol. Under the same treatment plan conditions, Treatment plans were designed by using five methods(Fixed-1cm, Fixed-2.5cm, Fixed-5cm, Dynamic-2.5cm Dynamic-5cm) and two pitches(0.43, 0.287). The accuracy of dose delivery for each treatment plan was analyzed by using EBT3 film and RIT(Complete Version 6.7, RIT, USA). Results: The accurate treatment plan that satisfying the prescribed dose of Target and the tolerance dose in normal organs(SMC Protocol) require scan range of at least 0.25cm for Fixed-1cm, 0.75cm for Fixed-2.5cm, 1cm for Dynamic-2.5cm, and 1.75cm for Fixed-5cm and Dynamic-5cm. As a result of AnalysisAnalysis by RIT. The accuracy of dose delivery was less than 3% error in the treatment plan that satisfied the SMC Protocol. Conclusion: In case of insufficient CT scan range in head and neck Tomotherapy^®, It was possible to make an accurate treatment plan by adjusting the FW among the setup parameter. If the parameter recommended by this author is applied according to CT scan range and is decide whether to re-CT or not, the efficiency of the task and the exposure dose of the patient are reduced.