• Journal of Biomedical Engineering Research
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• v.20 no.4
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• pp.409-417
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• 1999

Talairach atlas consists of three orthogonal sets of coronal, sagittal, and axial slices. This atlas has recently an important role as a standard brain atlas in diagnosing disease related with brain function and analyzing cause of brain disease. The 3D digital volume data set reconstructed from the atlas is widely applied to visualization and quantitative analysis of results processed in the digital computer. This paper represented application method of bi-linear interpolation technique, proposed tri-planar interpolation algorithm for 3D volume data reconstruction of Talairach atlas. And we implemented Talairach atlas editor and discussed problems in volume reconstruction of Talairach atlas. The bi-linear method was applied to only one set of the slices and considered the on intensity value in the interpolation process. The tri-planar technique concurrently uses three orthogonal sets of slices with the same information of brain structures. Talairach atlas editor visualized three sets. of atlas slices on the same coordinate and had editing function. Using the atlas editor, we represented problems in volume reconstruction by showing inconsistency of brain structures among three sets of atlas slices.

• Food Science and Preservation
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• v.10 no.3
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• pp.272-277
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• 2003

This study was conducted to determine the minimal processing characteristics as affected by the storage duration of whole Asian pears(Pyrus pyrifolia Nakai cv. Niitaka). Before and after storage for 4 months under air at 0$^{\circ}C$, whole pears were sliced, placed in unsealed plastic bags, and kept for 4 days at 10$^{\circ}C$. Storage of whole pears increased the initial levels of electrolyte leakage, total phenols and browning index and decreased the initial content of vitamin C in pear slices. Slices from stored pears maintained higher respiration rate compared with slices from non-stored pears during keeping. The increase of electrolyte leakage, browning index and microbial number and the decrease of total phenol in slices during keeping were more fast in slices from stored pears than in those from non-stored pears. These results suggest that the minimal processing characteristics of ‘Niitaka’ pears are depending upon storage duration.

• Toxicological Research
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• v.14 no.4
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• pp.483-488
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• 1998

During cerebral ischemia two important factors such as hypoxia and reduction of glucose can act as modulating stressor affecting the release of amine neurotransmitters including 5-hydroxytryptamine (5-HT). This study was performed to investigate the effect of glucose deprivation on the oxygen deprivation-induced changes of [3H]-5-HT release in the rat hippocampal slices. Experimental groups were divided into 4 groups for this study: normoxic/normoglycemic group, oxygen-deprived group, glucose-deprived group, and oxygen/glucose-deprived group. The hippocampus of rat brain was sliced by 400 $\mu\textrm{m}$ thickness with manual chopper. After 30 minutes preincubation in the normal buffer, the slices were incubated for 20 min in buffer containing [3H]-5-HT (0.1 M, 74 $\mu\textrm$Ci) for uptake. To measure the release of [3H]-5-HT into the buffer, the incubation medium was drained of and refilled with fresh buffer every ten minutes through a sequence of 14 tubes. Oxygen deprivation by gassing with 95% $N_2$/5% $CO_2$ and/or glucose deprivation was done in the 6th and 7th tube. The radioactivities in each buffer and the tissue were counted using scintillation counter. The results were expressed as fractional release. When slices were exposed to oxygen-deprived media for 20 min, the diminution followed by the rebound release of [3H]-5-HT was observed during the post-oxygen deprived period. However, glucose deprivation or oxygen/glucose deprivation markedly increased the release of [3H]-5-HT. which was opposite to the pattern observed in oxygen-deprived group. These results suggested that oxygen deprivation itself inhibits [3H]-5-HT release in rat hippocampal slices during oxygen-deprived period, but additional glucose deprivation convert the inhibitory response to increase of [3H]-5-HT release.

• Journal of Biomedical Engineering Research
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• v.44 no.1
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• pp.11-18
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• 2023

Currently, studies to predict the risk of rectal cancer surgery select MRI image slices based on the clinical experience of surgeons. The purpose of this study is to semi-automatically select and classify 2D MRI image slides to predict the risk of rectal cancer surgery using biomarkers. The data used were retrospectively collected MRI imaging data of 50 patients who underwent laparoscopic surgery for rectal cancer at Gachon University Gil Medical Center. Expert-selected MRI image slices and non-selected slices were screened and radiomics was used to extract a total of 102 features. A total of 16 approaches were used, combining 4 classifiers and 4 feature selection methods. The combination of Random Forest and Ridge performed with a sensitivity of 0.83, a specificity of 0.88, an accuracy of 0.85, and an AUC of 0.89±0.09. Differences between expert-selected MRI image slices and non-selected slices were analyzed by extracting the top five significant features. Selected quantitative features help expedite decision making and improve efficiency in studies to predict risk of rectal cancer surgery.

• Clinical and Experimental Pediatrics
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• v.52 no.5
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• pp.588-593
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• 2009

Purpose : To investigate whether growth hormone (GH) has a protective effect on neurons in hippocampal slice cultures of neonatal rats exposed to oxygen-glucose deprivation (OGD). Methods : Cultured hippocampal slices of 7-day-old rats were exposed to OGD for 60 min. Then, the slices were immediately treated with three doses of GH (5, 50, or $500{\mu}M$) in media. The relative fluorescent densities of propidium iodide (PI) uptake in the slices and relative lactate dehydrogenase (LDH) activities in the media were determined and compared between each GH- treated group of slices and untreated slices (control) at 12 and 24 h after OGD. Immunofluorescent staining for caspase-3 and TUNEL staining were performed to observe the effect of GH on apoptotic neuronal death. Results : The relative fluorescent densities of PI uptake in CA1 and dentate gyrus (DG) of the hippocampal slices in each GH-treated group were not significantly different from those in the untreated slices at 12 and 24 h after OGD (P>0.05). Treatment with GH could reduce the relative LDH activities in the media of the GH-treated groups only at 12 h after OGD (P<0.05). Expression of caspase-3 and TUNEL positivity in CA1 and DG of the slices treated with 50-iM GH were not different from those of the untreated slices at 12 and 24 h after OGD. Conclusion : Treatment of hippocampal slice cultures with GH after OGD does not show a definitive protective effect on neuronal death but can reduce the LDH efflux of the slices in media at 12 h after OGD.

• The Korean Journal of Physiology
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• v.30 no.2
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• pp.249-256
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• 1996

The effect of probenecid on the transport of tetraethylammonium (TEA) was studied in renal cortical slices and isolated membrane vesicles to investigate the interaction of organic anion with the organic cation transport system in proximal tubule. Probenecid reversibly inhibited TEA uptake by renal cortical slices in a dose-dependent manner over the concentration range of 1 and 5 mM. The efflux of TEA was not affected by the presence of 3 mM probenecid. Kinetic analysis indicated that probenecid decreased Vmax without significant change in Km. Probenecid inhibited significantly tissue oxygen consumption at concentrations of 3 and 5 mM. However, probenecid did not significantly reduce TEA uptake in brush border and basolateral membrane vesicles prepared from renal cortex even at a concentration as high as 10 mM. These results indicate that probenecid reduces TEA uptake in cortical slices by inhibiting tissue metabolism rather than by an interaction with the organic ration transporter.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1995.04a
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• pp.306-315
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• 1995

This paper presents a bin picking method using a slit beam laser in which a robot recognizes all of the unoccluded objects from the top of jumbled objects, and picks them up one by one. Once those unoccluded objects are removed, newly developed unoccluded objects underneath are recognized and the same process is continued until the bin gets empty. To recognize unoccluded objects, a new algorithm to link edges on slices which are generated by the orthogonally mounted laser on the xy table is proposed. The edges on slices are partitioned and classified using convex and concave function with a distance parameter. The edge types on the neighborhood slices are compared, then the hamming distances among identical kinds of edges are extracted as the features of fuzzy membership function. The sugeno fuzzy integration about features is used to determine linked edges. Finally, the pick-up sequence based on MaxMin theory is determined to cause minimal disturbance to the pile. This proposed method may provide a solution to the automation of part handling in manufacturing environments such as in punch press operation or part assembly.

• Journal of Mechanical Science and Technology
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• v.19 no.2
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• pp.692-703
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• 2005

In this paper, the energy and exergy analyses of the drying process of thin layer of eggplant slices are investigated. Drying experiments were conducted at inlet temperatures of drying air of 55, 65 and $75^{\circ}C$ and at drying air velocities of 1 and $1.5\;ms^{-1}$ in a cyclone type dryer. Using the first law of thermodynamics, energy analysis was carried to estimate the ratios of energy utilization. However, exergy analysis was accomplished to determine type and magnitude of exergy losses during the drying process by applying the second law of thermodynamics. It was deduced that eggplant slices are sufficiently dried in the ranges between $55-75^{\circ}C$ of drying air temperature and at 1 and $1.5\;ms^{-1}$ of drying air velocity during 12000-21600 s despite the exergy losses of $0-0.739\;kJs^{-l}.

• JSTS:Journal of Semiconductor Technology and Science
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• v.13 no.5
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• pp.423-429
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• 2013

A 6-Gb/s differential voltage mode driver is presented whose output impedance and pre-emphasis level can be controlled independently. The voltage mode driver consists of five binary-weighted slices each of which has four sub-drivers. The output impedance is controlled by the number of enabled slices while the pre-emphasis level is determined by how many sub-drivers in the enabled slices are driven by post-cursor input. A prototype transmitter with a voltage-mode driver implemented in a 65-nm CMOS logic process consumes 34.8-mW from a 1.2-V power supply and its pre-emphasized output signal shows 165-mVpp,diff and 0.56-UI eye opening at the end of a cable with 10-dB loss at 3-GHz.

• Communications for Statistical Applications and Methods
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• v.25 no.5
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• pp.513-521
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• 2018

The goal of sufficient dimension reduction (SDR) is to replace original p-dimensional predictors with a lower-dimensional linearly transformed predictor. The sliced inverse regression (SIR) (Li, Journal of the American Statistical Association, 86, 316-342, 1991) is one of the most popular SDR methods because of its applicability and simple implementation in practice. However, SIR may yield different dimension reduction results for different numbers of slices and despite its popularity, is a clear deficit for SIR. To overcome this, a fused sliced inverse regression was recently proposed. The study shows that the dimension-reduced predictors is robust to the numbers of the slices, but it does not investigate how robust its dimension determination is. This paper suggests a permutation dimension determination for the fused sliced inverse regression that is compared with SIR to investigate the robustness to the numbers of slices in the dimension determination. Numerical studies confirm this and a real data example is presented.