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Frequency of Food Allergy in Korea and the Causative Food Allergens (한국인의 식품 알레르기 빈도 및 알레르기 원인식품에 대한 연구)

  • 한재숙;홍상욱;김정숙;한준표;김능수
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.26 no.1
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    • pp.1-9
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    • 1997
  • To evaluate the prevalence of food allergies and the causative food allergens, 1,469 subjects in various age groups were studied by using a food Allergy questionnaire. Also, specific food antibodies were tested with the MAST method, a chemiluminescent assay, in 84 people who have a positive history of food allergies. The results were as follows : Among the total number of 1,469 subjects, about one- half of the total number(46.6%) have a family history of allergies. According to the questionnaire, the prevalence of food allergies was 11.4%. The group with a family history of allergies showed a higher Prevalence than the group without a family history. Skin allergies were the most common type of food allergies in both groups of male and female subjects. The questionnaire revealed mackerel as the most common food allergen, followed by the allergens of peach, pork, chicken, milk and eggs in decreasing order. According to the MAST allergy test, these diagnosed with an actual food allergy totalled 4.1% of the subjects. Peach and pork were the most common food allergens listed on the MAST results.

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Efficacy and Survival-associated Factors with Gefitinib Combined with Cisplatin and Gemcitabine for Advanced Non-small Cell Lung Cancer

  • Fang, Hong;Lin, Rong-Yan;Sun, Ming-Xia;Wang, Qian;Zhao, Yu-Liang;Yu, Jing-Lin;Tian, Yan;Wang, Xiao-Yun
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.24
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    • pp.10967-10970
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    • 2015
  • Objective: To analyze the efficacy and survival associated factors of gefitinib combined with cisplatin and gemcitabine for advanced non-small cell lung cancer. Materials and Methods: A total of 57 patients with advanced non-small cell lung cancer (NSCLC), who received platinum-based chemotherapy regimens for more than 1 cycle, were treated with gefitinib combined with cisplatin and gemcitabine until disease progression. Efficacy, survival time and adverse reactions were observed. The Kaplan-Meier method was adopted for analysis of survival and Cox regression for associated influencing factors. Results: The patients were followed up until October 31, 2013, and the median follow-up time was 19 months. Of 57 patients, there were 4 (7.0%) with complete remission (CR), 8 (14.0%) with partial remission, 31 (54.4%) with stable disease, and 14 (24.6%) with disease progression. The remission rate was 21.1% and the disease control rate was 75.4%. The median progression-free survival (PFS) time and the median overall survival time were 10 months and 15.2 months. The one-year, two-year and three-year survival rates were 47.4%, 23.3% and 10.0%. Gender and pathological types were the independent risk factors influencing PFS time (P=0.028, P=0.009). Tumor pathological type and early efficacy were independent factors for the prognosis (P=0.018, P=0.000). Adverse reactions were mostly rashes of I~II degree and diarrhea and slightly increasing level of aminopherase. The skin adverse event incidence of III degree or above was 1.8% (1/57) and brain metastasis was foudn in 31.6% (18/57). Conclusions: Gefitinib combined with cisplatin andgemcitabine, is effective for patients with IIIb~IV NSCLC who received multiple cycles of chemotherapy.

The Wearing Effect of Sport Underwear -Focusing on the Loss of Weight and Amount of Sweat according to the Materials- (운동용 속옷의 착용효과 -소재별 발한량과 체중감량을 중심으로-)

  • Na, Mi-Hyang;Kim, Mi-Sun;Jung, Bock-Hee
    • Korean Journal of Human Ecology
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    • v.11 no.3
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    • pp.273-285
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    • 2002
  • Three materials for sport underwear were manufactured by order for study, and among them, suitable material in order to perform an experiment on the effect of wearing was adopted. The results are as follows: The result of wearing an experimental clothes for sports manufactured as a foundation-type underwear for sports showed that if the same compositional materials were applied, laminating material had higher rate than that of others in the amount of sweat. Concerning relative humidity in clothes and the amount of sweat absorbed in clothes among the two kinds of materials which were produced by laminate, material 2(nylon+modal) was statistically exerts higher influence on the amount of sweat. The humidity in clothes keeps the optimal condition of 59.8%, and breast part showed the highest relative humidity. The material 2(nylon+modal) showed the highest comfortableness, the sense of warmth, humidity and voluminousness, and the sense of pressure. Follow-up survey revealed that in case of material 2, higher amount of sweat than that of the group objects in its early phase, and the amount of sweat varies from individuals. The temperature in clothes of folded parts of experimental clothes and maximum surface temperature was equivalent to that of average skin. With the lapse of time, the weight decreased of 11.03% in maximum, and 3.12% in minimum. The amount of change in the girth was greater in part of body frame than that of limbs, and especially, navel and waist part showed high decrease, and upper breast, breast and the largest part of abdomen showed relatively low decrease. The above experiment revealed that materials for suitable to the underwear for sports for loss of weight by an exercise should be made of doubled-nylon and modal, along with the laminate processing, which heightens the amount of sweat. Thus, wearing an experimental wear gave satisfaction in the view of the beauty of appearance as it did not discharge flowing secretion to the outside at the time of exercise.

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Study on Operating Limits of 5.56mm Rifle Overheat - Focusing on Human Engineering (5.56mm 소총 과열에 의한 운용한계 분석 - 인간공학 중심으로)

  • Lee, Ho-Jun;Choi, Si-Young;Shin, Tae-Sung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.9
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    • pp.49-56
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    • 2020
  • High temperature heat generated during rifle firing not only degrades the performance of the weapon, but also limits the user's operation. In this study, temperature change of handguard according to firing was measured with reference to Human Engineering criteria and the operability according to material was examined. Accordingly, for the firing test, three types of Korean rifle and one overseas model were selected for each material of handguard, and firing test was conducted using a contact type temperature meter. The test result shows that using a plastic handguard with low thermal conductivity and aluminum handguard with high thermal conductivity enabled the rifles to be operated with bare hands even when firing at more than 100 rounds at low atmospheric temperature. However, when firing more than 60 rounds at over 20℃ atmospheric temperature, aluminum handguard use is limited. When firing quickly over 100 rounds, handguard use is restricted regardless of its fabrication material. To eliminate operational limitations by overheating, it is necessary to eliminate direct contact with skin using gloves, vertical grips, etc. This study examined the operability of rifles in terms of thermal risk, and the resulting study results are expected to be used as basic data for Human Engineering of other rifles and munitions.

Breeding of Black Tomato 'Hei' for Protected Cultivation (시설재배용 흑색토마토 신품종 '헤이' 육성)

  • Seo, Jong-Bun;Shin, Gil-Ho;Jang, Mi-Hyang;Lee, Ya-Seong;Jung, Hyo-Jin;Yoon, Bong-Ki;Choi, Kyong-Ju
    • Horticultural Science & Technology
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    • v.31 no.6
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    • pp.833-836
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    • 2013
  • 'Hei' is a new cultivar of red with black flesh; originated from the cross of two inbred lines, mother plant, TKUI separated from 'Kame' in 2007 and father plant, TLB separated from tomato collected in Europe by pedigree breeding method. 'Hei' was tested for specific character and productivity of lines of tomatoes in spring for 2 years, 2008 to 2009. This variety had resistance to powdery mildew. 'Hei' is an indeterminate type. The fruit shape is round and the skin color is blackish red. The average fruit weight of 'Hei' is about 127.9 g and marketable yield is $5,715kg{\cdot}10a^{-1}$. Lycopene contents of 'Hei' are about $18.5mg{\cdot}100g^{-1}$, high compared with other tomato ($3.1mg{\cdot}100g^{-1}$). 'Hei' is suitable for environment-friendly protected cultivation because of resistance to powdery mildew.

Salvage of Infected Breast Implants

  • Song, Joon Ho;Kim, Young Seok;Jung, Bok Ki;Lee, Dong Won;Song, Seung Yong;Roh, Tai Suk;Lew, Dae Hyun
    • Archives of Plastic Surgery
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    • v.44 no.6
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    • pp.516-522
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    • 2017
  • Background Implant-based breast reconstruction is being performed more frequently, and implants are associated with an increased risk of infection. We reviewed the clinical features of cases of implant infection and investigated the risk factors for breast device salvage failure. Methods We retrospectively analyzed 771 patients who underwent implant-based breast reconstruction between January 2010 and December 2016. Age, body mass index, chemotherapy history, radiation exposure, and smoking history were assessed as potential risk factors for postoperative infection. We also evaluated the presence and onset of infection symptoms, wound culture pathogens, and other complications, including seroma, hematoma, and mastectomy skin necrosis. Additionally, we examined the mastectomy type, the use of acellular dermal matrix, the presence of an underlying disease such as hypertension or diabetes, and axillary node dissection. Results The total infection rate was 4.99% (58 of 1,163 cases) and the total salvage rate was 58.6% (34 of 58). The postoperative duration to closed suction drain removal was significantly different between the cellulitis and implant removal groups. Staphylococcus aureus infection was most frequently found, with methicillin resistance in 37.5% of the cases of explantation. Explantation after infection was performed more often in patients who had undergone 2-stage expander/implant reconstruction than in those who had undergone direct-to-implant reconstruction. Conclusions Preventing infection is essential in implant-based breast reconstruction. The high salvage rate argues against early implant removal. However, when infection is due to methicillin-resistant S. aureus and the patient's clinical symptoms do not improve, surgeons should consider implant removal.

Knowledge on the chemical disinfectants among dental workers in some Daejeon region (대전 일부 지역 치과종사자의 화학소독제에 관한 지식도 연구)

  • Min, Hee-Hong;Ahn, Kwon-Suk
    • Journal of Korean society of Dental Hygiene
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    • v.7 no.4
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    • pp.455-470
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    • 2007
  • The usage of appropriate disinfectants is essential for infection control in dental hospitals, dental clinics. Inadequate use of disinfectants is the cause of human or environmental toxicity and is a waste of cost. This study was aimed to assess the level of knowledge on the disinfection and chemical disinfectants among dental workers in dental hospitals, dental clinics. It's ultimately intended to serve as a basis for the preparation of more effective, appropriate educational programs on the disinfection and manuals on the use of disinfectants for dental workers. This study enforced a questionnaire with 184 dental workers employed in dental hospitals, dental clinics from 15 Aug. to 15 Sep. 2007, in the area of Daejeon. The obtained result were as follows; 1. The population sociological feature of dental hospital and dental clinic showed that significant differences of dental service career(pM0.039). Dental service career of dental workers shows; below 3 years 42.9%, 4~6 years 34.7%, more than 7 years 22.4% in dental hospitals, below 3 years 30.4%, 4~6 years 26.7%, more than 7 years 43.0% in dental clinics(pM0.039). 2. The average score of dental workers knowledge in 'Critical item soaks in high-level disinfectants for 20minutes was 2.73V0.49 point, got from knowledge of dental instrument is appropriate to immerse before sterilization in the dental device disinfection(pM0.002). 3. In the general disinfection which it follows in education experience of chemical disinfectants direction for use, 'Direction for use by Spaulding process classification' responded that the correct answer was the education experience dental workers 60.0%, the education non-experience dental workers 39.5%(p=0.026). 4. In the dental device disinfection which it follows in education experience of chemical disinfectants direction for use. 'High level disinfection is not applied for the non-critical items and equipment' responded that the education experience dental workers 49.2%, the education non-experience dental workers 31.9%(pM0.045), 'Semi-critical items is applied same method in presence of the infection disease which it acts responded that the education experience dental workers 44.6% answer back, the education non-experience dental workers 24.4%(pM0.017). 5. 'A hand disinfectants of anticeptics have effect' the education experience dental workers 78.5% answer back, the education non-experience dental workers 52.9%(pM0.003). 1t uses with hand disinfectants when the instruments which be imbrued and patient contact', the education experience dental workers 78.5% answer back, the education non-experience dental workers 62.2%(pM0.026), 'Boric acid solution uses for the skin disinfectants the education experience dental workers 52.3% answer back, the education non-experience dental workers is 37.0%(pM0.016), 'Gluconate have effective difference which it follows in chemical disinfectant consistency and the solution type' education experience dental workers 72.3% answer back, education non-experience dental workers 47.9%(pM0.004). 6. The education experience dental workers were appeared higher than the education non-experience dental workers in knowledge of the disinfection and chemical disinfectants. Consequently system and the specialty education which is standardized continuously must be provided to all dental workers.

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A Documentary Study on Herb, Dmgs used for Vitiligo -With an emphasis on classifying kinds, excess and weakness syndrome, the changes of medical methods and factors by each epoch mentioned in the relative documentary records (백반증(白斑症) 사용약물(使用藥物)에 대한 문헌적(文獻的) 고찰(考察) -관련문헌(關聯文獻)에 나타난 백반증(白斑症)의 상용약물(常用藥物) 종류(種類), 허실(虛實), 시대(時代), 원인별(原因別) 분류(分類)를 중심(中心)으로-)

  • Lee, Sun-Dong
    • The Journal of Korean Medicine
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    • v.16 no.2 s.30
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    • pp.44-61
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    • 1995
  • Arranging 63 kinds of separate volumes and papers published on Oriental medicine, I could get the result as follows. 1. The herbs for internal application used commonly in vitiligo are 155 kinds totally. The herbs for external application are 67 kinds. The herbs for external and internal both application examined into 23 sorts. 2. Herbs for weakness syndrome in vitiligo are 49 kinds. Another type, excess syndrome is 105 sorts, the'latter is roughly twice as many as the former. 3. It is as follows that the results of study in relations to kinds, factors, and medical treatments of herbs about vitiligo in and out of the country with the division of former times to 1900, 1901 to 1980, 1981 to 1990, and 1991 to the latest day. In comparative study of inner and outer of thc country about factors and medical treatments of vitiligo in chronicle classification, its factors in the internal documents are classified by outside factors. Although there arc the differences of factors by each epoch, however, the factors of vitiligo according to external documents are blood stasis(血熱), deficiency of um of the liver and kidneys(肝腎陰虛), deficiency of blood(血虛), excess of exhaustion(勞倦過多) etc. Moreover, the medical treatment is more diverse and the differences by each epoch as to the medical treatment is also put down more saliantiy than in internal documents. 4. In comparison with herbs in experimental and no experimental documents, herbs applied for weakness syndromes in experimental method are 40 kinds totally. The herbs in no experimental methods are 35 kinds. The herbs used by experimental method are 65 kinds. The common herbs for excess syndrome by no experimental method are 78 kinds. We can see comparable difference from kinds of herbs used by experimental method. In brief, there are the differences classified by each epoch in Oriental medicine for treatment. Especially one of the most important feature, the frequency in use of weakness syndrome herbs has increased more than that of excess syndrome herbs. In external documents (china) and experimental study, generally the differences of common herbs and factors have disappeared through many experimentsitudy. The classification of its factors have been fractionalized clinically. Besides, in Western medicine and Orienal medicine, vitiligo tends to be prescribed not to simple skin disease but a mental and physical disease, a whole body and an internal disease.

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Characteristic Evaluation of Exposed Dose with NORM added Consumer Product based on ICRP Reference Phantom (ICRP 기준팬텀 기반의 천연방사성핵종이 포함된 가공제품 사용으로 인한 피폭선량 특성 평가)

  • Yoo, Do Hyeon;Lee, Hyun Cheol;Shin, Wook-Geun;Choi, Hyun Joon;Min, Chul Hee
    • Journal of Radiation Protection and Research
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    • v.39 no.4
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    • pp.159-167
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    • 2014
  • In Korea, July 2012, the law as called 'Act on Safety Control of Radioactive Rays Around Living Environment' was implemented to control the consumer product containing Naturally Occurring Radioactive Material (NORM), but, there are no appropriate database and effective dose calculation system. The aim of this study was to develop evaluation technique of the exposure dose with the use of the consumer products containing NORM and to understand the characteristics of the exposed dose according to the radiation type and energy. For the evaluate of exposure dose, the ICRP reference phantom was simulated by the MCNPX code based on Monte Carlo method, and the minimum, medium, maximum energy of alphas, betas, gammas from the representative NORM of Uranium decay series were used as the source term in the simulation. The annual effective doses were calculated by the exposure scenario of the consumer product usage time and position. Short range of the alpha and beta rays are mostly delivered the dose to the skin. On the other hand, the gamma rays mostly delivered the similar dose to all of the organs. The results of the annual effective dose with $1Bq{\cdot}g^{-1}$ radioactive stone-bed and 10% radioactive concentration were employed with the usage time of 7 hours 50 minute per day, the maximum annual effective dose of alphas, betas, gammas were calculated 0.0222, 0.0836, $0.0101mSv{\cdot}y^{-1}$, respectively.

Anti-wrinkle Effect of Morinda citrifolia (Noni) Extracts (노니 추출물의 주름개선 효과연구)

  • Lee, Jung-Noh;Kim, Sang-Woo;Yoo, Young-Kyoung;Lee, Ghang-Tai;Lee, Kun-Kook
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.32 no.4 s.59
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    • pp.227-231
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    • 2006
  • Wrinkle formation is mainly attributed to the environmental factors such as UV rays, air pollution, smoking and stress etc. Especially, UV rays induce premature skin aging which is characterized by deep wrinkle, leathery dryness etc. Recently, researches on the wrinkle formation and its prevention have been the main theme in cosmetics fields. We have studied the various plant extracts having anti-wrinkle effects and finally showed that Noni (Morinda citrifolia) extracts have the efficacy of promoting the type I collagen synthesis in normal human fibroblast, using PICP assay. We purified one active compound from Noni extracts and identified its structure. It was identified as 6,7-Dimethoxy-2H-1-Benzopyran-2-one; scopoletin by $^1H-NMR,\;^{13}C-NMR,$ IR, Mass analysis. Scopoletin increased collagen synthesis in a dose dependent manner (89.5% at $0.2{\mu}g/mL$). In order to verify the anti-aging effectiveness of the cream containing 3% noni extracsts, we performed the in vivo test with some female volunteers for 12 weeks. It reduced the signs of aging, especially face wrinkles. From these results, we conclude that the noni extracts could be used as an useful anti-wrinkle agent.