• 대한한의학원전학회지
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• 제24권1호
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• pp.95-105
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• 2011

The cough is generally known as a symptom occurred from Lung. But it was descriptive of the symptom every internal organs can cause in "HwangjenaegyeongSomun Haelon". The reason is that, when a pathogenic Gi attack human body, the body skin which have the relationship to Lung is attacked firstly. But the internal organs preside over each seasons of the year, so the season's presiding organ is ultimately attacked. And in "Somun Haelon" the partner symptoms of five solid organs cough and six hollow organs cough are being described, so we can distinguish between each internal organs coughs. Clinically, the cough is most common symptom and one of the most difficult symptom. In my opinion, the origin organ of cough is very various, but the doctor fix their thinking to the Lung, so the cough became a most difficult symptom. This thesis describe pathogenesis and partner symptoms of five solid organs cough and six hollow organs cough. And illustrate clinical examples and some medical prescriptions. Intend to show that various treatment after differentiation of syndromes[辨證施治] surely needed for effective curing of a cough.

• 대한한의정보학회지
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• 제14권2호
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• pp.73-79
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• 2008

Objectives : We investigated the correlation of the skin color to blood circulation on the face of Korean female by noninvasive-skin measuring devices. Methods : Korean female(37.47${\pm}$3.66 years, n=36) aged 30-45 years were participated in this study. We measured the skin color of the face with Spectrophotometer CM2600d (Minolta, Japan) and the skin blood flow with Laser Doppler Imaging-Periscan PIM II (Perimed AB, Sweden). The skin color and blood circulation of three groups (30-35 years, 36-40 years, 41-45 years) divided on age were analyzed by paired-t test and regression analysis. Results : The L* values of the skin were decreased and the a* values were increased significantly with age. This means that the more age increase, the more the skin is dark and red. But the skin blood flow was not significantly different with age and skin color. Conclusions : In the oriental medicine, It was reported that the face of the female over 35 years is changed gradually haggard and the blood circulation is decreased. In our study, the blood circulation was not changed and the skin color was dark and red with increasing the age. We think this symptom resulted from the better nutrition than the past, the change of the blood-quality and this changes were too sensitive to be measured by Laser Doppler Imaging system.

• 대한암한의학회지
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• 제22권1호
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• pp.13-22
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• 2017

Objective: The purpose of this study is to report the effect of Nobongsangki-Jeong on skin rash caused by Olmutinib. Methods: A female Non-Small cell lung carcinoma patient (Adenocarcinoma, Stage IV, Epidermal Growth Factor Receptor positive) suffered from skin rash due to the side effect of Olmutinib administration. She was treated with Nobongsangki-Jeong for the symptom management for 14 days. The clinical outcomes were measured by numeric rating scale (NRS) and National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE) version 4.03. Results: After treatment, skin rash was improved from NRS 5 to 1. Pruritus and pain of skin were improved from NCI-CTCAE grade 2 to 1. Conclusion: This case study suggests that Nobongsangki-Jeong may have the efficacy for the treatment of skin rash caused by Olmutinib.

• 대한한방체열의학회지
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• 제2권1호
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• pp.17-23
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• 2003

Purpose The cold hypersensitivity is a subjective symptom and it is very difficult to evaluate the severity. It is possible to detect cold hypersensitivity by measuring the skin temperature on DITI, but there is limitation only using DITI to find the objective grade of the symptom. To set a new objective standard for the diagnosis of cold hypersensitivity, we examined the relationship between the Visual Analogue Scale (VAS) score for the cold hypersensitivity and the change of skin temperature on hands by cold stress test Method 23 patients with symptom of cold hypersensitivity were participated as subjects who visited the women medical center of Kangnam Kyunghee Korean Hospital, Kyung Hee Univ. from May 1, 2002 to August 31, 2002. There were all carefully examined to rule out other disease such as obesity, skin diseases, spinal nerve lesions and external wounds. Thermographic observations for this study were made using DITI. We performed cold stress test three times to compare with the results from thermographic observations by DITI: first, after 15 minutes-resting, second, right after 1 minutes soak in $20^{\circ}C$ water, the third for last, 10 minutes after the soak. VAS score was chosen to determine the severity of cold hypersensitivity. Result 1 male and 22 female patients were participated ranging in age from 22.17 to 45.21. There was a significant negative correlation between the recovery rate of finger skin temperature after cold stress test and the VAS score. And there was a significant positive correlation between the difference of finger skin temperature and the back and palm of hands after cold stress test and the VAS score. Conclusion In cold hypersensitivity patients, the cold stress test combined with DITI could be a accurate method for the objective evaluation of cold hypersensitivity, especially good at deciding the severity by numeric values. Using a more strict criterion, as diagnosing of cold hypersensitivity, and longer follow-up may improve the validity of the results attained in clinical trials.

• Pediatric Infection and Vaccine
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• 제3권2호
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• pp.168-174
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• 1996

Purpose : Aseptic meningitis is relatively frequent in children and caused mostly by enterovirus. The aim of the present study was to determine the effect of early diagnosis (spinal tapping) on symptom duration of childhood aseptic meningitis. Methods : One hundred fifty-three children who were hospitalized due to aseptic menigitis in the Department of Pediatrics St. Benedict Hospital from July 1996 through October 1996 were included in this study. Patients were divided to two groups according to the duration from first symptom onset to diagnosis. Early diagnosis group is diagnosed within 3 days from first symptom onset. Later diagnosis group is diagnosed after 4 days from first symptom onset. Results : 1) The average age of these patients was 4.3 years old in early diagnosis group and 4.1 years old in later diagnosis group. The sex ratio(male: female) was 2.04:1 in early diagnosis group and 2.5:1 in later diagnosis group. 2) The mean duration of diagnosis of this study was 2.04 day in early diagnosis group and 5.12 day in later diagnosis group. 3) The percentage of symptom and sign of the early diagnosis group were fever(100%), headache(88.4%), vomiting(86.9%), abdominal pain(39%), neck stiffness(36.2%), skin rash(18.8%), diarrhea(16.9%) and that of later diagosis group were fever(100%), headache(83.3), vomiting(80.9%), abdominal pain(47.6%), neck stiffness(41.6%), skin rash(29.7%), diarrhea(16.6%). 4) Initial CSF findings revealed leukocyte $146.8{\pm}386.3/mm^3$ with PMNL 38%, protein 32.47mg/dl, sugar 66.23mg/dl in early diagnosis group and leukocyte $458.1{\pm}663.2/mm^3$, protein 31.22mg/dl, sugar 64.21 mg/dl in later diagnosis group. 5) There was no statistically significant differance in the peripheral blood findings between early diagnosis group and later diagnosis group. 6) The duration of disappearance of symptom after spinal tap were 2.3 days in early diagnosis group and 2.24 days in later diagnosis group. Total symptom duration was 4.34 days in early diagnosis group and 7.36 days in later diagnosis group. Conclusions : Our results demonstrate that early diagnosis(early spinal tap) shortened duration of clinical symptoms.

• 원예과학기술지
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• 제33권1호
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• pp.55-60
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• 2015

과피흑변은 '부유' 단감(Diospyros kaki, 'Fuyu') 과실의 저장 중에 발생하는 주요 생리적 장해의 하나이다. 부유 과실의 과피에서 페놀화합물의 함량, PPO와 POD의 활성, 지질 포화도를 분석하였다. 페놀화합물은 일광의 방향에 따라 과피에 불균등하게 분포하였는데, 일광 노출면에 축적량이 가장 많았고 그 반대면에서는 가장 적었다. 그러나 수관 내부의 음지 가지에서 수확한 과실의 경우 페놀화합물은 과피에 비교적 고르게 분포되어 있었다. PPO와 POD의 활성 또한 과피에서 고르지 않았으나, 이는 과피흑변이 발생한 과실에서만 그러하였으며, 흑변 부위는 PPO 활성은 가장 높고 POD 활성은 가장 낮았다. 수확 시에 일광면에 표식을 한 과실을 저온에 저장하였을 때, 저장 중 과피흑변의 증상인 운형 흑반은 정확히 표식 부위에 발생하였다. 게다가, 일광면은 높은 지질포화도를 보였는데, 이는 일광에 의해 야기된 고온에 대한 적응을 의미한다. 따라서 이러한 결과로 미루어 볼 때, 부유 과실의 과피흑변 장해는 일광에 노출된 과실의 고온 순화 과피 조직에서 나타나는 저온장해 증상의 일종인 것으로 간주할 수 있을 것이다.

• 혜화의학회지
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• 제18권2호
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• pp.131-140
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• 2009

The aim of this study is to find out benefits of symptom questionnaire for oriental medical treatments. We analyzed symptom questionnaire of Korean association of abdomen diagnosis and treatment. Conclusions are as below. 1. Appetite, taste and digestion have a deep connection with accumulation and muscular contracture, with which the method of reinforcement and reduction is decided. 2. Feces, urine and, sweat have a deep connection with accumulation and water, with which the method of diaphoresis, emesis and purgation is decided. 3. Thirst and chillness and fever have a deep connection with water poisons and feverish feeling, based on which the cold and heat is classified. 4. we can find out the lesions with departmentalized physical sections of the head and the face, the chest, the abdomen, the articulations, the limbs and the skin. 5. It is possible to select appropriate prescription and assess before & after treatment through the questionnaire.

• 기본간호학회지
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• 제12권2호
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• pp.180-185
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• 2005

Purpose: The purpose of this study was to investigate the incidence and self care practice for nausea/vomiting in patients with cancer during chemotherapy. Method: The participants were 100 patients with cancer over 20 years of age who visited the outpatient department or were hospitalized for chemotherapy Self care in the case of nausea and vomiting was measured by the Dodd's scale. Data were analyzed using the SAS program and the following statistics were used frequency, percentage, unpaired t test, and Pearson correlation coefficient. Results: The ratio of the occurrence of nausea/ vomiting in the participants was 70.0%. The incidence of nausea/ vomiting was significantly higher for women than for men. The incidence of nausea/ vomiting was also higher for patients with cancer not in the gastro-intestinal system (GIS) compared to that for patients with GIS cancer. The incidence of nausea/ vomiting positively correlated with anorexia, skin injury, and fatigue. Conclusion: The ratio of occurrence of nausea/ vomiting for the participants was 70.0%. The incidence of nausea/ vomiting was higher fur women and patients with cancer not in the GIS. The incidence of nausea/ vomiting positively correlated with anorexia, skin injury, and fatigue. The results indicate that nausea/vomiting is a frequent symptom, particularly in women and there is a need to provide interventions to decrease the effects of this symptom.

• 동의생리병리학회지
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• 제19권3호
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• pp.821-825
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• 2005

A boy who was eight years old visited the Dept. of Oriental Medical Ophthamology & Otolaryngology & Dermatology Hospital, Dongeui University with allergic purpura. He was suffering from the purpuric rash occurring on the lower extremities and the edema of leg. We treated a patient with only Oriental Medicine(a internal use of the herbal medicine, Dangguisusangamibang and a acupuncture). After four days or so, the symptom of the skin disease was recovered remarkably. The second case, a different boy who was ten years old visited the same hospital with allergic purpura. He was suffering from the purpuric rash occurring on the lower extremities, too. We also treated a patient with only Oriental Medicine(internal use of the herbal medicine, Dangguisusangamibang and a acupuncture). After one weeks or so, the symptom of the skin disease was improved remarkably, we think that these are good cases to treat with Oriental Medicine, Dangguisusangamibang. We suggest that the Oriental Herb medicine, Dangguisusangamibang have an effect with allergic purpura which means Podoyug in Oriental medicine.

• Tuberculosis and Respiratory Diseases
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• 제78권1호
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• pp.27-30
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• 2015

The drug reaction with eosinophilia and systemic symptom (DRESS) syndrome is a severe adverse drug-induced reaction which includes a severe skin eruption, fever, hematologic abnormalities (eosinophilia or atypical lymphocytes) and internal organ involvement. The most frequently reported drug was anticonvulsants. The diagnosis of DRESS syndrome is challenging because the pattern of cutaneous eruption and the types of organs involved are various. The treatments for DRESS syndrome are culprit drug withdrawal and corticosteroids. Here we report a 71-year-old man with skin eruption with eosinophilia and hepatic and renal involvement that appeared 4 weeks after he had taken anti-tuberculosis drugs (isoniazid, ethambutol, rifampicin, and pyrazinamide), and resolved after stopping anti-tuberculosis drugs and the administration of systemic corticosteroids. DRESS recurred after re-challenging isoniazid, we identified isoniazid was causative drug.