• 동의생리병리학회지
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• 제31권4호
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• pp.213-219
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• 2017

Atopic dermatitis (AD) is a common skin disease characterized by chronic and relapsing inflammatory dermatitis with immunological disturbances. Spleen deficiency (脾虛) is one of the major causes of AD, so development of animal model is required for AD research that reflects the pattern identification. The groups that we have used in this study included Senna folium extracts (SFE), 2,4-dinitrochlorobenzene (DNCB), and normal mice. Therefore, the present study was developed to atopic dermatitis mouse model with spleen deficiency in 2,4-dinitrochlorobenzene (DNCB) and senna leaves extracts induced AD in NC/Nga mice. The results demonstrated that senna leaves extract treatment significantly increased the dermatitis clinical score and epidermal thickness in AD-like skin lesions. We also proved beyond doubt that there was occurrence of erythema and skin moisture indices in the senna leaves extract groups. Further, we also found that the level of serum immunoglobulin E (IgE) in the senna leaves extract-treated group was increased. The amount of IL-4, IL-13, $TNF-{\alpha}$ and $TGF-{\beta}$ mRNA determined by real-time PCR was increased remarkably when senna leaves extract groups were treated on dorsal skin. Senna leaves extract groups significantly promoted the number of CD11B+/Gr-1 cell in skin, as well as the number of CD4+/CD8+ cell in dorsal skin compared with control. The review summarizes recent process in our understanding of the immunopathophysiology of spleen deficiency AD and the implications for spleen deficiency mouse models of AD on drug discovery from medical plants.

• 대한가정학회지
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• 제37권12호
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• pp.193-203
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• 1999

This study was executed to show influence of material and property of sportswear to physiological responses of body and comfort sensation and to supply basic research data about comfortable sportswear Trainning wear was manufactured with cotton(C) and hygroscopically treated polyester material (FP), and its properties of material were measured. Then rectal temperature, skin temperature, heart rate, weight loss, clothing microclimate and subjective sensation was estimated with study of wearing with these sportswear and examined the influence that it got to physiological responses of body and sensation. Health adult men were selected for subjects and executed at climatic chamber of temperature, $20\pm2^{\circ}C and humidity, $60\pm5%$ R.H. Conclusively sportswear of hygroscopically treated polyester is a favorable functional material. So far factor that affect to physiological comfort sensation has been explained mostly by moisture regain but in our experiment, it turned out that air permeability, water absorption velocity and dynamic oater absorption etc. were affecting factors. So according to this result, air permeability and moisture permeability should be considered with transmittance of temperature moisture for development of comfort material.

• Journal of the Korean Wood Science and Technology
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• 제43권6호
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• pp.810-817
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• 2015

본 연구는 백합나무 스킨팀버의 ACQ-2, CUAZ-3, CuHDO-1 가압처리 특성을 평가하기 위해 수행되었다. 일차적으로 백합나무 변재부와 심재부 시험편을 대상으로 처리용 목재 함수율이 방부제 처리도에 미치는 영향을 평가하고, 방부제 유효성분인 구리의 처리목재 내 정착 특성을 조사하였다. 본 연구 결과에 의하면 백합나무 변재부는 방부제 종류에 관계없이 조사된 목재함수율 범위(50% 이하)에서 사용환경 범주 H3용 처리목재의 침윤도와 흡수량 기준을 모두 만족하였다. 백합나무 변재부의 방부제 보유량 경사를 조사한 결과, 국립산림과학원 고시 제2011-04호에 제시된 처리용 목재의 함수율(평균 30% 이하)을 만족할 경우 재면으로부터 15 mm 깊이까지에서 사용환경 범주 H3용 처리재의 흡수량 기준을 충족하였다. 백합나무 심재부는 처리도가 매우 불량하여 처리용 목재의 함수율 조건 및 방부제 종류에 관계없이 사용환경 범주 H3용 처리목재의 침윤도와 보유량 기준을 모두 만족시키지 못하였다. 백합나무 변재 및 심재 시험편 공히 비건조 양생보다 건조 양생에서 구리의 정착속도가 빠르고 또한 최종 구리 정착율이 높았으며, 3주간 비건조 양생 후 구리 정착율이 90% 수준에 머물었으며 양생기간을 연장하더라도 정착율은 크게 개선되지 않았다.

• 한국산학기술학회논문지
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• 제13권7호
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• pp.2886-2894
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• 2012

본 연구는 서울소재 대학교에 재학 중인 여대생을 대상으로 피부미용전공과 비전공 여학생들의 피부건강관리의 관심도와 피부상태, 인식 및 관리 행위의 차이점 및 관련성을 파악하고자 하였다. 전공자들과 비전공자들의 대한 비교 분석은 동일한 생활권에서 궁극적으로 전문 학습과 비 전문학습의 일반적인 상태에 대한 지식과 행위를 의미하는 것으로, 연구결과는 다음과 같이 나타났다. 전공 여대생이 비전공 여대생에 비해 피부건강에 대한 관심도가 높은 것으로 유의미한 차이가 있었다(p<.01). 피부미용 전공 여대생은 복합성 피부, 비전공 여대생은 건성 피부가 많은 것으로 유의미한 차이를 보였다(p<.05). 피부 관리 실태에서 색조화장 후 전공여부에 따른 이중세안 정도, 각질 정리 횟수, 마사지나 팩 관리횟수, 선크림 사용 항목에서 각각 유의미한 차이가 있었다(p<.01, p<.001, p<.01, p<.01). 오백식품 및 인스턴트식품의 영향정도와 수분섭취 항목에서 각각 유의미한 차이를 보였다(p<.001).(p<.05). 화장품 사용은 다양한 채널을 통해 효율적인 구매를 하는 경향이었으며, 탁월한 기능이 있을 때는 경제적 부담이 있어도 구입 의향 항목에서 적극적인 성향인 것으로 유의미하게 나타났다(p<.001). 본 연구의 결과는 피부미용 산업 및 교육 분야에 기초자료로 활용되고자 하였다.

• 패션비즈니스
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• 제3권1호
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• pp.125-137
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• 1999

The present study aims to reveal the sweating reaction of male adults, focused on athletes. With six subjects (3 athletes and 3 non-athletes) in two different conditions of ambient temperature (I : $25\pm1.0^{\circ}C$, II : $29.5\pm1.0^{\circ}C$), their total sweat rate, local sweat rate, skin temperature, physiological reaction (rectal temperature, blood pressure, and pulse rate), and psychological reaction (thermal, moisture, comfort, and perceptive sweat sensations) were measured. The comparison gave the following results: Total sweating rate was greater in non-athletes, while the two groups had more perspiration in ambience II. Local sweating rate in both ambiences was the greatest in the central breast area (athletes) and the infrascapular area (non-athletes). The mean skin temperature had more changes of increase and decrease in athletes. As to physiological reaction, non-athletes had lower rectal temperature and blood pressure as well as higher pulse rate. As for psychological reaction in Ambience II, the 4 sensations were mostly 'hot', 'humid', 'uncomfortable', and 'sweaty'.

• 한국식품조리과학회지
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• 제19권1호
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• pp.72-78
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• 2003

This study was conducted to investigate the physicochemical and organoleptic characteristics and freshness of wild and cultivated Paralichthys olivaceus during storage. By the results of morphological observation, wild Paralichthys olivaceus had white abdomen, light black skin and transparent muscle, but cultivated Paralichthys olivaceus had black spotted abdomen, dark black skin and dark pink muscle. Moisture contents of wild and cultivated Paralichthys olivaceus were similar, but the lipid content was higher in cultivated Paralichthys olivaceus than that of wild Paralichthys olivaceus. Sensory scores of appearance, taste, texture and overall acceptability were higher in wild Paralichthys olivaceus than that of cultivated Paralichthys olivaceus. The reason was that lipid content was higher in cultivated Paralichthys olivaceus The freshness of cultivated Paralichthys olivaceus seemed to last shorter than that of wild one due to rapid increase of the volatile basic nitrogen content, pH and total microbial count during storage.

• 대한화장품학회지
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• 제47권1호
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• pp.49-56
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• 2021

본 연구에서는 ceramide, 당지질, cholesterol, 지방산을 이용하여 피부 지질 조성과 유사한 조성비를 갖는 액정 에멀젼을 제조하고 편광 현미경을 통해 제형 내 액정 입자를 확인하고, cryso-SEM을 이용하여 다층구조가 형성되었음을 확인하였다. 상기 제조된 샘플은 1 개월간 상온에 보관하여 액정구조가 지속적으로 유지되는 것을 현미경 관찰을 통해 확인하였다. 또한, 이렇게 제조된 액정 에멀젼을 포함하는 크림 조성물을 제조하고, 3 차원 인공피부를 활용한 ceramide 피부 투과 효율을 확인하였다. 해당 크림 조성물을 활용하여 임상시험을 진행하고 일반 에멀젼 대비 피험자의 피부 수분 보유량(skin hydration), 경피 수분 손실량(TEWL)을 측정함으로써 피부 장벽 개선에 대한 임상 실험 결과를 확인하였다.

• Archives of Plastic Surgery
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• 제34권5호
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• pp.587-592
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• 2007

Purpose: In case of postburn flexion contracture of the fingers, skin graft, geometrical relaxation techniques, local flap, and free flap have been used. Among these procedures, full-thickness skin grafts from the inguinal area are widely used to reconstruct a postburn flexion contracture in the fingers. But there are many esthetic and functional problems in this procedure. Especially, hyperpigmentation of the skin-grafted fingers poses a troublesome problem, particularly in the patients who have dark colored skin. To solve the problem, we have used pulp graft which was harvested from the lateral aspect of great toe. In the present study, we report pulp graft, with which we have obtained a good result in the treatment of postburn flexion contracture of the fingers. Methods: Between September of 2004 and August of 2006, great toe pulp graft was performed to 20 sites of 15 patients. After release of the postburn flexion contracture using Z-plasty, the composite tissue (pulp) harvested from the lateral aspect of great toe was grafted on the raw surface. Moisture dressing with ointment and foam dressing material was performed. Stratum corneum of the graft got stripped off in two to four weeks after pulp graft. The color of the pulp graft was slightly reddish, then it became similar to the adjacent tissue. Results: There was complete take in all the patients who were treated with pulp graft. Great toe pulp graft provided similar color and texture to the adjacent skin, high rate of graft take, and left only a minimal scar at donor site. Conclusion: Thick keratin layer and inelastic nature of the pulp make this type of the graft much easier and simpler, and ensure a better take. Pulp graft is useful method for the reconstruction of the postburn flexion contracture in fingers.

• 한국환경보건학회지
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• 제39권4호
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• pp.360-368
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• 2013

Objectives: Phthalates are used in a large variety of products including as coatings of pharmaceutical tablets, film formers, stabilizers, dispersants, emulsifying agents, and suspending agents. They have been the subject of great public concern in recent years. The extensive uses of this material have attracted attention and issues regarding its safety have been raised. Methods: In this study, three types of phthalate skin permeation were studied using matrixes such as ointments, creams and lotions in vitro. The absorption of phthalate diesters [Dimethyl phthalate (DMP), Di-n-propyl phthalate (DPP) and Di-n-pentyl phthalate (DNPP)] using film former has been measured in vitro through rat skin. Epidermal membranes were set up in Franz diffusion cells and their permeability to PBS measured in order to establish the integrity of the skin before the phthalates were applied to the epidermal surface. Results: Absorption rates for each phthalate ester were determined and permeability assessment made to quantify any irreversible alterations in barrier function due to contact with the esters. Types of phthalate in vitro experimental results quickly appeared in the following order DMP > DPP ${\geq}$ DNPP. Conclusions: In the experimental results, lotion> cream> ointment, and the permeation rate of lotion with a great amount of moisture was the fastest. Skin permeation rate is generally influenced by the chemical characteristics of a given chemical, such as molecular weight and lipophilicity. As the esters became more lipophilic and less hydrophilic, the rate of absorption decreased.

• 한국산학기술학회논문지
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• 제11권11호
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• pp.4455-4459
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• 2010

호호바오일 마사지가 건조피부에 미치는 효과를 알아보고자, 건조피부로 평가된 10명을 대상으로, 한쪽 팔에는 호호바오일 마사지를, 다른 쪽 팔에 아무것도 적용하지 않았다. 호호바오일 마사지 그룹은 호호바오일을 이용, 10분간의 팔 마사지를 주 2회로 총 8회 실시하였다. 실험 결과 호호바오일 마사지를 한 그룹은 유분과 수분의 함유량이 증가하였다. 특히, 마사지의 횟수가 증가 될수록 피부에서의 유 수분은 증가하는 것을 알 수 있었다(유분 : t=-7.470, p<0.001(팔안쪽)/t=-4.666, p<0.01(팔바깥쪽), 수분 :t=-3.966, p<0.01(팔안쪽)/t=-6.847, p<0.001(팔바깥쪽). 따라서 호호바오일 마사지는 건조피부를 개선시키는 효과가 있는 것으로 확인되었다.