• 한국환경보건학회지
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• 제38권4호
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• pp.340-350
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• 2012

Objectives: This study was conducted to investigate skin and eye symptoms according to swimming pool user characteristics and chlorine concentration at indoor swimming pools in the Daegu region. Methods: A total of 296 swimming pool users were enrolled from the eight swimming pools randomly chosen in Daegu. Each user completed a self-administered questionnaire with general, swimming related, and symptoms suffered throughout December 2008 to August 2009. The water analysis of swimming pools was substituted with the swimming pool water analysis practiced by district offices to 2008. Results: There were significant differences in experience rate of self-reported skin and eye symptoms between coaches and students except dander. The users of swimming pools having higher chlorine concentrations suffered from more frequent skin and eye symptoms. The results of multiple logistic regression analysis for experience of skin symptoms showed that coaches (OR = 6.81, 95% CI: 2.46~18.81) and pools with chlorine concentrations over 0.4 mg/l (OR = 1.75, 95% CI: 1.01~3.03) were the significant variables. For experience of eye symptoms, coaches (OR = 4.13, 95% CI: 1.25~13.69) at a swimming pool was the significant variable. Conclusions: Increased exposure to swimming pool water and exposure to swimming pool showed that higher chlorine concentration may cause more frequent skin and eye symptoms.

• Journal of Ginseng Research
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• 제41권4호
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• pp.456-462
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• 2017

Background: Abnormal activation of matrix metalloproteinases (MMPs) plays an important role in UV-induced wrinkle formation, which is a major dermatological problem. This formation occurs due to the degeneration of the extracellular matrix (ECM). In this study, we investigated the cutaneous photoprotective effects of Ultraflo L treated ginseng leaf (UTGL) in hairless mice. Methods: SKH-1 hairless mice (6 weeks of age) were randomly divided into four groups (8 mice/group). UTGL formulation was applied topically to the skin of the mice for 10 weeks. The normal control group received nonvehicle and was not irradiated with UVB. The UV control (UVB) group received nonvehicle and was exposed to gradient-UVB irradiation. The groups (GA) receiving topical application of UTGL formulation were subjected to gradient-UVB irradiation on $0.5mg/cm^2$ [GA-low (GA-L)] and $1.0mg/cm^2$ [(GA-high (GA-H)] of dorsal skin area, respectively. Results: We found that topical treatment with UTGL attenuated UVB-induced epidermal thickness and impairment of skin barrier function. Additionally, UTGL suppressed the expression of MMP-2, -3, and -13 induced by UVB irradiation. Our results show that topical application of UTGL protects the skin against UVB-induced damage in hairless mice and suggest that UTGL can act as a potential agent for preventing and/or treating UVB-induced photoaging. Conclusion: UTGL possesses sunscreen properties and may exhibit photochemoprotective activities inside the skin of mice. Therefore, UTGL could be used as a potential therapeutic agent to protect the skin against UVB-induced photoaging.

• 한국산학기술학회논문지
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• 제12권11호
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• pp.4756-4763
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• 2011

본 연구는 일본 관광객의 한국 피부미용 서비스 이용 후 만족 및 재방문 의도를 분석하기 위한 것으로 한국피부관리실 이용경험이 있는 일본인 남녀를 대상으로 분석하였으며 다음과 같은 결론을 얻었다. 첫째, 소비자의 피부관리실 이용동기 유형에 따른 선택속성의 분석결과, 이용동기 유형에 따라 선택속성 요인은 차이가 있는 것으로 나타났다. 둘째, 선택속성이 피부관리실 소비자 만족에 미치는 영향의 분석결과, 피부관리실 선택속성은 부분적으로 소비자 만족에 영향을 미치는 변인으로 나타났다. 셋째, 선택속성이 피부관리실 이용 후 재방문 의도에 미치는 영향의 분석결과, 피부관리실 선택속성이 소비자만족에 미치는 영향을 분석한 결과와 일관성 있는 결과를 나타내어 피부관리실 이용 후 재방문 의도에 영향을 미치는 선택 속성 요인은 서비스 및 가격보다는 시설 및 피부관리실, 피부관리실 이미지 및 부대서비스 요인을 더 중요하게 고려하는 요인임이 분석되었다. 넷째, 피부관리실 이용 후 소비자 만족은 재방문 의도에 영향을 미치는 요인으로 분석되었다.

• 융합정보논문지
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• 제9권10호
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• pp.264-271
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• 2019

현재 청소년들은 대중매체의 근접성에 의한 외모적 아름다움을 중요시 하고 있다. 따라서 피부에 발생하는 여드름은 중증의 질병은 아니지만 잘못 관리하면 안면부에 흉터와 자국을 남기게 되고 이는 학생들의 자신감을 상실시키고 우울증과 스트레스를 동반한다. 이에 본 연구에서는 여드름 피부가 청소년의 스트레스, 우울증, 자아존중감에 어떠한 영향을 미치는 가를 분석하여 여드름을 단순한 피부질환의 하나로 생각할 것이 아니라 정신건강에도 밀접한 관계가 있음을 인지하고 여드름 피부를 관리하는데 좀 더 효과적이며 피부를 관리하는 기초자료로 활용하고자 3가지 가설을 수립하였다. 그 결과 중학생의 여드름 발생이 스트레스와 우울증에 정(+)의 영향을 미치는 것으로 나타나 여드름 피부관리는 표면적 관리가 아닌 정신건강에 필요한 관리로 사료된다.

• 여성건강간호학회지
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• 제15권1호
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• pp.32-42
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• 2009

Purpose: This study was done to examine the effects of abdominal breathing on VAS-Anxiety (VAS-A), blood pressure, peripheral skin temperature and saturation oxygen in pregnant women in preterm labor. Method: The study design was a matched control group interrupted time series. Forty-six women matched to gestational age were assigned to either the experimental group (26) or control group (20). Data were collected between March 2007 and May 2008. For the experimental treatment the women performed abdominal breathing 30 times, which took 5 minutes, and did one set of 5-minute abdominal breathing daily for three days. Data collection was done before and after the abdominal breathing to measure VAS-A, blood pressure, peripheral skin temperature and oxygen saturation. Descriptive, $X^2$, Mann-Whitney U tests were used to analyze the data with the SPSS/PC+Win 15.0 program. Result: For the experimental group there were significant decreases in VAS-A (Z=-4.37, p=.00), systolic blood pressure (Z=-3.38, p=.00), and an increase in skin temperature (Z=-4.50, p=.00) and oxygen saturation (Z=-3.66, p=.00). Conclusion: These findings suggest that abdominal breathing in pregnant women in preterm labor results in decreases in anxiety(VAS-A) including biological evidences such as systolic blood pressure, and increases in peripheral skin temperature and oxygen saturation. Further longitudinal study is needed on the lasting effects and obstetric and neonatal outcomes following abdominal breathing.

• 대한임상검사과학회지
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• 제40권2호
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• pp.118-128
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• 2008

The aim of this study was to investigate the effect of electrical stimulation on healing of impaired wound and alteration of mast cells in experimental diabetic rats. Thirty male Sprague-Dawley rats were divided into three groups : incision (control), diabetes+incision (diabetes) and diabetes + incision + electrical stimulation (D/ES). Diabetes was induced in rats by streptozotocin (STZ) injection (60 mg/kg, one time) and 20 mm length incision wounds were created on the back after shaving hair. The electrical stimulation rats were treated with a current intensity of 30~50 V at 120 pps and $140{\mu}s$ for 10 days from 3 days after STZ injection. The lesion and adjacent skin tissues were fixed with 10% buffered formalin, embedded with paraffin. For wound healing analysis, hematoxylin-eosin (HE) and picrosirius red staining were performed. Mast cells (MC) were stained with toluidine blue (pH 0.5) and quantified at ${\times}200$ using a light microscope. The density of keratinocyte proliferation and microvessels in skin tissues were analyzed using a computerized image analysis system on sections immunostained with proliferative cell nuclear antigen (PCNA) and ${\alpha}$-smooth muscle actin (${\alpha}$-SMA), respectively. The results showed that the wound healing rate, collagen density and neoepidermis thickness, density of PCNA-positive cells and density of ${\alpha}$-SMA-positive vessels were significantly higher in D/ES rats than in diabetic rats. The density of MCs and degranulated MCs in D/ES rats were also significantly higher than those in diabetic rats. These findings suggest that the electrical stimulation may promote the tissue repair process by accelerating collagen production, keratinocyte proliferation and angiogenesis in the diabetic rats, and MCs are required for wound healing of skin in rats.

• Archives of Plastic Surgery
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• 제38권4호
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• pp.552-554
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• 2011

Purpose: Though its general usage, traditional tie-over dressing using suture has a few drawbacks such as difficulty in re-fixation after its opening especially when hematoma or seroma has occurred. It is rather difficult to maintain a stable dressing on curvy parts of body like flank, buttocks and that leads to unsatisfactory results of the surgery. Authors recommend a quick and repeatedly doable method, tie-over dressing that incorporates the usage of hooks and rubber bands. Methods: Debridement was done at a recipient site to be able to do skin graft. A right size of skin graft was prepared and placed upon the defect site with suture. Enough number of hooks were attached using Blue nylon at the normal skin of the edge of grafted area. We Applied dressing with ointment and fluffy gauze then fixed the dressing by attaching a rubber band at the hook to give a certain amount of tension. One or two days after the surgery, we opened the tie-over dressing and repeated the tie-over dressing by reusing the hooks and rubber band. Results: The skin grafts were all successfully taken and by repeating tie-over dressing using hooks and rubber, we could take the advantage of shortened the dressing time and eliminate the inconvenience of the patient and the surgeon by using bandages and fixing tapes. Conclusion: The advantage of tie over dressing using hooks and rubber bsnds are its easy re-doability early detection of probable complications, preventability of reoccurence of hematoma and seroma. Therefore, authors report this as considering the tie-over dressing using hooks and rubber bands is recommendable.

• 한국식품영양학회지
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• 제30권1호
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• pp.9-18
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• 2017

As an indicator of skin health, acidified skin surface pH ranging from 5 to 7 is crucial for maintaining skin barrier. In this study, we evaluated the relationship between skin pH and dietary pattern (DP) as well as nutrient or food intake in 48 healthy middle aged adults. Skin pH was measured in the skin surface of the inner arm, and blood lipid profile was analyzed. Dietary intake data were obtained using 1 day 24 hour recall method, and DP was extracted using factor analysis. Results revealed that skin pH ranged from 5.15 to 6.88 in all subjects. There was no significant difference in skin pH between males and females. When subjects were grouped by tertile of skin pH, the food intake of fruit, and the nutrient intake of omega 6 fatty acid, potassium, vitamin A, vitamin C, ${\beta}$-carotene, and riboflavin in the first tertile group with skin pH ranging from 5.15 to 5.68 were significantly higher than in the third tertile group with skin pH ranging from 6.26 to 6.88. There was no difference in blood lipid profile between the first and the third tertile group. Among 5 DP extracted by factor analysis, DP5 characterized by a high intake of nuts and fruits as well as a low intake of beverages and alcohol was inversely correlated with skin pH after adjusting for gender and age. DP5 was positively correlated with nutrient intake of carbohydrate, fiber, potassium, iron, vitamin A, vitamin C, ${\beta}$-carotene, thiamine, and riboflavin but negatively correlated with sodium after adjusting for gender, age, smoking, and energy intake. Therefore, acidified skin pH could be maintained by these DP and nutrients.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2155-2157
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• 2013

Advances and controversies of skin cancer prevention in the Asian-Pacific region are to be examined in the world's first Global Controversies and Advances in Skin Cancer Conference to be held in Brisbane, Australia this November. APOCP Members are cordially invited to register early for the opportunity to contribute to the debate on a cancer which continues to be a prominent issue in the Asia Pacific and indeed worldwide. We need answers to the questions of why a cancer that is so preventable and easily detectable is still shrouded in controversy. Primary focuses will be on issues like viral involvement, vaccines and novel clinical approaches.

• Archives of Plastic Surgery
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• 제38권2호
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• pp.189-193
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• 2011

Purpose: Mucinous eccrine carcinoma of the skin is rare skin adnexal malignant tumor, which most commonly occurs in the head and neck regions. This tumor, although rarely metastatic, has a high incidence of local recurrence. We report a case of mucinous eccrine carcinoma developed on the Lt. cheek which was treated by Mohs surgery. Methods: The patient was a 53-year-old man who showed a palpable skin-colored $1.5{\times}1.5cm$ sized mass on Lt. cheek. We treated it by wide excision, but it recurred several times on the same region. So we finally did the Mohs surgery and full thickness skin graft. Results: The histologic characteristics are large mucinous pools with fibrous septae and clusters of tumor cells. Special stains showed that the mucin was positive reactivity on Periodic acid Schiff. Also the immunocytochemical studies showed a positive reactivity to carcinoembryonic antigen, S-100 protein, cytokeratin-7. Therefore pathologist reported it as a mucinous eccrine carcinoma. Conclusion: Authors experienced a rare case of primary mucinous eccrine carcinoma on Lt. cheek which had recurred several times. Because of the high local recurrence rate, we did the Mohs surgery and got an good result. Therefore the early Mohs surgery would be a good choice to primary mucinous eccrine carcinoma.