Korean Journal of Clinical Laboratory Science (대한임상검사과학회지)
- Volume 40 Issue 2
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- Pages.118-128
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- 2008
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- 1738-3544(pISSN)
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- 2288-1662(eISSN)
Effects of Electrical Stimulation on Wound Healing and Skin Mast Cells in Streptozotocin-Induced Diabetic Rats
스트렙토조토신 유도 당뇨 흰쥐에서 전기자극이 상처치유와 피부 비만세포에 미치는 영향
- Jekal, Seung-Joo (Department of Clinical Laboratory Science, Wonkwang Health Science College) ;
- Lee, Kyung-Sun (Department of Clinical Laboratory Science, Wonkwang Health Science College) ;
- Chung, Ok-Bong (Department of Clinical Pathology, Jeonju Kijeon College) ;
- Lee, Jae-Hyoung (Department of Physical Therapy, Wonkwang Health Science College)
- Published : 2008.12.31
Abstract
The aim of this study was to investigate the effect of electrical stimulation on healing of impaired wound and alteration of mast cells in experimental diabetic rats. Thirty male Sprague-Dawley rats were divided into three groups : incision (control), diabetes+incision (diabetes) and diabetes + incision + electrical stimulation (D/ES). Diabetes was induced in rats by streptozotocin (STZ) injection (60 mg/kg, one time) and 20 mm length incision wounds were created on the back after shaving hair. The electrical stimulation rats were treated with a current intensity of 30~50 V at 120 pps and