• Journal of Pharmaceutical Investigation
• /
• v.39 no.3
• /
• pp.217-219
• /
• 2009

There are several approaches to calculate a sample size for bioequivalence test. Among these approaches, sample sizes determination based on Schuirmann's two one-sided tests procedures has been used most popularly in case of 2${\times}$2 bioequivalence study. Here we proposed simple sample size table for conventional 2${\times}$2 bioequivalence test based on Schuirmann's two one-sided tests in accordance with Korean Guidelines for Bioequivalence Test. This table will allow researchers with a little statistical background to calculate the sample size for bioequivalence with easy process.

• Physical Therapy Rehabilitation Science
• /
• v.8 no.2
• /
• pp.112-123
• /
• 2019

Objective: Based on the results of previous studies, it is necessary to analyze gait and discuss and present the effects of aquatic exercise for chronic stroke. The purpose of this study was to present objective data on the effect of aquatic exercise on the gait of persons with stroke by performing a meta-analysis. Design: A systematic review and meta-analysis. Methods: We performed a meta-analysis of 23 studies that investigated the effects of aquatic exercise performed between 2006 and 2017. The studies were searched on the basis of the participants, intervention, comparison, outcomes standard. The quality of the research method was assessed using a tool that can assess the risks posed by each study design. A meta-analysis software program was used to calculate the mean effect size, effect size by intervention, and effect size by outcome. We also performed a meta-regression analysis and an analysis of publication bias. Results: The mean effect size of the patients' gait was 0.65 (p<0.05). The largest effect size by outcome was observed at the 6-m walk test, followed by the 6-minutes walk test, 10-m walk test, and the walking equipment test (p<0.05). The meta-regression analysis showed that the effect size increased with increased duration, number, and length of sessions. Conclusions: Aquatic exercise appears to show a moderate effect on the gait of chronic stroke survivors. Meta-analyses on the effects of aquatic exercise in other patient populations are needed. This study suggests standard criteria establishments for the effect of aquatic exercise on the walking ability of persons with chronic stroke.

• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2016.10a
• /
• pp.98-99
• /
• 2016

Oyster shell is light weighted and its strength characteristic is similar to sand so we have reviewed to find its suitability of aggregate. Therefore we found fineness modulus and size distribution of oyster shell by grinding it with inverter cutter mill varying inverter speed and screening size. In our test, the fineness modulus has tendency of decrease in higher speed and tendency of increase in bigger diameter of screening size. 5~2.5mm, 2.5~1.2mm, 1.2~0.6mm, and below 0.6mm of oyster shell particle size could be used in further test for suitability of aggregate.

• Journal of the Korean Institute of Landscape Architecture
• /
• v.24 no.1
• /
• pp.55-64
• /
• 1996

The size of leisure space has been determined on the basis of the annual and peak day's number of visitor, turnover rate, and size per visitor. But the past models have no theoretical base and practical errors on the many cases. So, this study was carried out to build and test a new theoretical model for selecting a optimal size of theme park. The basic concept of the model building is the break-even point analysis of cost-volume-profit relation. That is, Gain-Loss of theme park is determined by marginal profit and fixed cost by size. YongIn Farmland was selected as a model test case.

• Proceedings of the Korean Geotechical Society Conference
• /
• 2005.03a
• /
• pp.1126-1133
• /
• 2005

The effects of mean particle size and uniformity coefficient of dredged soils to the liquefaction resistance strength and dynamic characteristics are experimentally studied in this paper. Representative 4 mean particle sizes and 3 uniformity coefficients were selected and 12 representative particle size distribution curves which have different mean particle sizes and uniformity coefficients, were artificially manufactured using the real dredged river soil. Cyclic triaxial tests and torsional shear tests were carried out to analyze the effect of mean particle size and uniformity coefficient to the liquefaction resistance strength and dynamic characteristics of soils.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2005.06a
• /
• pp.619-622
• /
• 2005

Purpose of this study is to investigate the size-dependent mechanical properties in micron scale medium. Theories such as the couple stress theory and strain gradient theory explain that the deformation in the micron scale is dependent upon the size of the medium. Specimens of the cantilever type, bridge type and paddle type beam that have thickness of 900, 1000 and 1200 nm and width of 10, 20, 30 and $50{\mu}m$ were fabricated by the MEMS technique. We carried out the bending and torsion test to measure the mechanical properties such as the young's modulus, yield strength and torsional rigidity using the AFM(Atomic Force Microscopy).

• Proceedings of the International Microelectronics And Packaging Society Conference
• /
• 2002.05a
• /
• pp.130-133
• /
• 2002

Solder leaching resistance of the metal electrode is an important factor with regard to adhesion properties of ceramic substrate. In the Low Temperature Co-fired Ceramics (LTCC), Ag-Pd or Ag-Pt pastes are used instead of pure Ag paste to prevent leaching. Solder leaching behavior of the Ag-Pd paste in relation to LTCC raw material powder size was investigated. First fabrication of LTCC green tape with different particle size was done. LTCC substrates with Ag-Pd electrode were prepared using conventional multilayer ceramic process. Dipping test was performed to test solder leaching behavior of the electrode. Ag-Pd electrode on LTCC substrate with smaller particle size achieved higher solder leaching resistance.

• Proceedings of the KSME Conference
• /
• 2004.04a
• /
• pp.13-18
• /
• 2004

The objective of this study is to investigate fracture toughness and fatigue crack propagation behavior in the Reduced Activation Ferritic Steel (RAFs) JLF-I. The fracture toughness tests were performed with various size(plane size and thickness) and various side groove of specimens. The fatigue crack propagation behavior of the JLF-I steel was investigated by the constant-amplitude loading test for the stress ratios R=O.I, 0.3 and 0.5 respectively. The effects of stress ratios and specimen size on the fatigue crack growth behaviors for JLF-I steel were discussed within the Paris law. The test results showed the standard CT specimen with the side groove of 40 % represented a valid fracture toughness. The fracture resistance curve increased with increasing plane size and decreased with increasing thickness. However, the fracture resistance curve of half size specimen was similar to that of the standard specimen. The fatigue crack propagation rate of a half size specimen was similar to that of a full size specimen at the stress ratios of 0.1, 0.3 and 0.5 respectively. The fatigue crack propagation behavior of this material were evaluated by using a half size specimen.

• Journal of the Korean Statistical Society
• /
• v.3 no.1
• /
• pp.3-12
• /
• 1974

The two-stage sequential test, suggested by Baker [2] for testing hypotheses $H_0:\mu=\mu_0$ and $H_1:\mu=\mu_1$ of $N(\mu,\sigma^2)$ with the unknown $\sigma^2$ would not be amenable for applications unles some cluses on the choice of the first-stage sample size are available. The study in this paper is intended to shed some light on the size of the first-stage sample. An approximate method is used to estimate an optimal initial sample size that minimizes the average sample number. In brief, the optimal size is a strictly monotone decreasing function of the quantity $(\mu_1-\mu_0)/\sigma$. Empirical and simulation results are used to ascertain the negligible effect of possible errors due to approximations and assumptions used.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.36 no.1
• /
• pp.143-149
• /
• 2016

This study evaluated the shear behavior of geogrid reinforced ballast material using a large scale direct shear test and discrete element method (DEM) based on PFC 3D program. The direct shear test was conducted on ballast materials that have different particle size distributions. Whereas the test results revealed that the shear strength generally increased with the larger particle size of ballast material without geogrid reinforcement, the shear behavior of ballast material was found to change pertaining to the relationship between particle size distribution and geogrid rib size. Generally, it is deemed the effectiveness of reinforcement can be achieved when the rib size is two times greater than average particle size. A numerical analysis based on DEM was conducted to verify the test results. The geogrid modeling was successfully completed by calibration process along with sensitivity analysis to have actual tensile strength provided by manufacturer. With a given geogrid model, the parametric evaluation was further carried out to examine the interactive behavior between geogrid and ballast material. Consequently, it was found that the effectiveness zone of geogrid reinforcement generated within a specific depth.