• Title/Summary/Keyword: size effect model

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Comparison of Film Measurements, Convolution$^{}$erposition Model and Monte Carlo Simulations for Small fields in Heterogeneous Phantoms (비균질 팬텀에서 소조사면에 대한 필름측정, 회선/중첩 모델과 몬테 카를로 모사의 비교 연구)

  • 김상노;제이슨손;서태석
    • Journal of Biomedical Engineering Research
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    • v.25 no.2
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    • pp.89-95
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    • 2004
  • Intensity-modulated radiation therapy (IMRT) often uses small beam segments. The heterogeneity effect is well known for relatively large field sizes used in the conventional radiation treatments. However, this effect is not known in small fields such as the beamlets used in IMRT. There are many factors that can cause errors in the small field i.e. electronic disequilibrium and multiple electron scattering. This study prepared geometrically regular heterogeneous phantoms, and compared the measurements with the calculations using the Convolution/Superposition algorithm and Monte Carlo method for small beams. This study used the BEAM00/EGS4 code to simulate the head of a Varian 2300C/D. The commissioning of a 6MV photon beam were performed from two points of view, the beam profiles and depth doses. The calculated voxel size was 1${\times}$1${\times}$2$\textrm{cm}^2$ with field sizes of 1${\times}$1$\textrm{cm}^2$, 2${\times}$2$\textrm{cm}^2$, and 5${\times}$5$\textrm{cm}^2$. The XiOTM TPS (Treatment Planning System) was used for the calculation using the Convolution/Superposition algorithm. The 6MV photon beam was irradiated to homogeneous (water equivalent) and heterogeneous phantoms (water equivalent + air cavity, water equivalent + bone equivalent). The beam profiles were well matched within :t1 mm and the depth doses were within ${\pm}$2%. In conclusion, the dose calculations of the Convolution/Superposition and Monte Carlo simulations showed good agreement with the film measurements in the small field.

The Anti-tumor Effect of Polysaccharide from the Leaves of Panax Ginseng C.A. Meyer(MB40) in a Murine Squamous Cell Carcinoma Model (편평세포암 동물 모델에서 고려인삼잎-다당체(MB40)의 항암치료효과)

  • Joo, Eun-Jung;Choi, Jun;Chung, Eun-Jae;Hong, Seok-Jin;Cho, Jae-Gu;Baek, Seung-Kuk;Woo, Jeong-Soo;Jung, Kwang-Yoon;Kwon, Soon-Young
    • Korean Journal of Head & Neck Oncology
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    • v.25 no.1
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    • pp.3-7
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    • 2009
  • Background and Objectives : Panax ginseng C.A. Meyer is a medical plant that has been widely utilized as a tonic and nutritional agent since ancient times in Korea. Ginseng has anti-metastatic property of cancer and immunomodulating activity. The novel acidic polysaccharide compound(MB40) was isolated from the leaves of Panax ginseng C.A. Meyer. To determine immunomodulating activities of MB40, we evaluate anti-cancer and anti-metastatic effects of MB40 in tumor bearing immune competent mice. Material and Methods : C3H mice were divided into three equal groups(Cisplatin treatment group, MB40 treat-ment group, Cisplatin and MB40 treatment group) and were transplanted SCC(Squamous Cell Carcinoma) cells(2${\times}$106) to the lateral side of abdomen. From day 4 after transplantation, MB40 was administrated at dose of 10mg/kg, respectively, every other day by intratumoral injection. Cisplatin was systemically administrated at doses of 1mg/kg, respectively, every week by intraperitoneal injection. Results : 5 days after administration, tumors can be palpated in every mice group. After 13 days of administration, the mice group to which MB40 were administrated exhibited reduction in tumor size respectively, compared to cisplatin group. Overall status of mice such as body weight and activity were superior in MB40 group than cisplatin group. Conclusion : The result of this study indicates MB40 may have significant therapeutic effect and decreases complications induced by systemic chemotheraphy. MB40 may be developed as a novel and potent immunotropics to improve the cell immune system and anti-cancer drug for the treatment of cancer patients in head and neck squamous cell carcinoma.

INFLUENCE OF NICKEL-TITANIUM SPREADER ON THE SEALING ABILITY IN LATERAL CONDENSATION TECHNIQUE (측방가압충전시 Nickel-Titanium spreader의 사용유무가 근관충전효과에 마치는 영향)

  • Min, Kyung-San;Hong, Chan-Ui;Cho, Yong-Bum
    • Restorative Dentistry and Endodontics
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    • v.25 no.3
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    • pp.381-389
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    • 2000
  • Lateral condensation with gutta-percha and sealer has been shown to provide an excellent apical seal; however, the lateral condensation technique has demonstrated less favorable apical leakage results in curved canals when compared with straight canals. Placement of endodontic spreaders to within 1 to 2mm of the root canal working length has been advocated for optimum gutta-percha obturation. Due to their stiffness, stainless-steel(SS) spreaders will often fail to achieve this position in curved canals. Newly marketed nickel-titanium(NT) spreaders may offer an advantage in this regard due to the increased flexibility of these instruments. The purpose of this study was to evaluate the effect of NT finger spreader on the sealing ability in lateral condensation technique, compared with conventional SS finger spreader. Twenty four standardized resin models simulating curved canals(30 degree) were randomly placed into 2 groups and instrumented to a #30 master apical file size with Ni-Ti Profile .04 taper series using step down technique. Each groups was obturated with standardized gutta-percha cone by standard lateral condensation technique using SS finger spreader, NT finger spreader. And then, each model was sectioned horizontally with microtome at 1, 2, 3, 4, 5mm levels from the apex. At each of 5 levels, ratio of the area of gutta-percha was obtained by calculating the area of gutta-percha to the total area of the canal. The data collected were then analyzed statistically using a t test for independent samples. The results as follows ; 1. The total mean ratio of area of gutta-percha was 89.20${\pm}$7.00(%) for SS spreader group. 92.20${\pm}$5.17(%) for NT spreader group. There was statistically significant difference between each group(p<0.05). 2. At 3mm level, the mean ratio of area of gutta-percha was 88.32${\pm}$5.41(%) for SS spreader group, 95.25${\pm}$2.60(%) for NT spreader group. There was statistically significant difference between each group(p<0.05). At 1,2,4mm levels, NT spreader group showed greater mean ratio of area of gutta-percha than SS spreader group, too. But there was no statistically significant difference. 3. At 5mm level, the mean ratio of area of gutta-percha was 91.83${\pm}$3.42(%) for SS spreader group, 87.91${\pm}$3.68(%) for NT spreader group. There was statistically significant difference between each group(p<0.05). This study concluded that the NT spreader demonstrated somewhat favorable apical sealing effect than SS spreader in prepared curved canals. The clinical use of NT spreaders may enhance our ability to create better apical seals in curved canals, but further studies in this area will help clarify some of the remaining areas with which practitioners are concerned, such as compaction forces exerted by NT spreaders.

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Characterization of Schottky Diodes and Design of Voltage Multiplier for UHF-band Passive RFID Transponder (UHF 대역 수동형 RFID 태그 쇼트키 다이오드 특성 분석 및 전압체배기 설계)

  • Lee, Jong-Wook;Tran, Nham
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.44 no.7 s.361
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    • pp.9-15
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    • 2007
  • In this paper, we present the design of Schottky diodes and voltage multiplier for UHF-band passive RFID applications. The Schottky diodes were fabricated using Titanium (Ti/Al/Ta/Al)-Silicon (n-type) junction in $0.35\;{\mu}m$ CMOS process. The Schottky diode having $4{\times}10{\times}10\;{\mu}m^{2}$ contact area showed a turn-on voltage of about 150 mV for the forward diode current of $20\;{\mu}A$. The breakdown voltage is about -9 V, which provides sufficient peak inverse voltage necessary for the voltage multiplier in the RFID tag chip. The effect of the size of Schottky diode on the turn-on voltage and the input impedance at 900 MHz was investigated using small-signal equivalent model. Also, the effect or qualify factor of the diode on the input voltage to the tag chip is examined, which indicates that high qualify factor Schottky diode is desirable to minimize loss. The fabricated voltage multiplier resulted in a output voltage of more than 1.3 V for the input RF signal of 200mV, which is suitable for long-range RFID applications.

Application of Relative Gravity Surveying and Modeling to Sinkhole Detection (싱크홀 탐지를 위한 상대중력측량과 중력모델링 기법의 활용)

  • Kim, Jinsoo;Lee, Young-Cheol;Lee, Jung-Mo
    • Korean Journal of Remote Sensing
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    • v.33 no.3
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    • pp.267-274
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    • 2017
  • The purpose of this research was to develop and present methods to detect sinkholes which can exist underneath the surface of the ground. First, we buried a water tank with dimensions $1.8{\times}0.8{\times}0.8m$ at a distance of 1.8 m from the surface. This played the role of the sinkhole. Secondly, we created a square zone with sides 12 meters away from the buried water tank. Within this zone, we measured the gravity at 1-meter intervals using a Scintrex CG5 relative gravimeter with a resolution of 0.001 mGal. Additionally, we performed three-dimensional (3-D) gravity modeling to calculate the theoretical values of the relative gravity around our model sinkhole. The resulting values for the relative gravity around the sinkhole depended on the method used. The measured effect of gravity was 0.036 mGal and the effect calculated using 3-D modeling was 0.024 mGal. Our results suggest that sinkholes that are similar in size to the water tank used in this study can be detected using relative gravity surveys. Smaller sinkholes can be detected by reducing the intervals between the relative gravity measurements.

Effect of Partially Oxidized Ti Powder on Electrical Properties and Microstructures of $BaTiO_3$-based Ceramics ($BaTiO_3$계 세라믹스의 전기적 성질과 미세조직에 미치는 부분산화 Ti 분말 첨가의 영향)

  • Kim, Jun-Gyu;Jo, Won-Seung;Park, Gyeong-Sun
    • Korean Journal of Materials Research
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    • v.10 no.10
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    • pp.671-676
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    • 2000
  • $BaTiO_3$-based ceramics with partially oxidized Ti powders were prepared by sintering at $1350^{\circ}C$ for 1 h in v vacuum, and then heated in air. In this study, the effect of partially oxidized Ti powders on electrical properties and microstructures of $BaTiO_3$-based ceramics was investigated. It was found out that the semiconductive $BaTiO_3$-based ceramics beζame to show excellent PTCR (more than $10^5$) characteristic by adding 5~7 vol% of partially oxidized Ti powder. Also, it was found out that the sintered compact had extremely porous and fine-grained microstructure. The relative density and grain size of sintered compact with 5 vol% of partially oxidized Ti powders were 54% and $1.3\;{\mu\textrm{m}}$, respectively. The mechanism for the development of PTCR characteristic in $BaTiO_3$-based ceramics with partially oxidized Ti powders due to the adsorption of oxygen at grain boundaries, and could be explained, based on Heywang model.

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The Effect of Corporate Social Responsibility Activities on Brand Equity and Consumer Attitude (사회적 책임활동이 브랜드자산과 소비자태도에 미치는 영향 연구)

  • Park, Nam-Goo;Choi, Ho-Gyu
    • Journal of Distribution Science
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    • v.12 no.8
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    • pp.17-29
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    • 2014
  • Purpose - The use of corporate social activities to implement the concept of corporate social responsibility enhances brand equity and attitude, and strengthens economic competitiveness. In areas such as mobile communications, companies take the responsibility of protecting customers and enhance the quality of the mobile communication service, helping to make an effort to obey the regulations of the public trade order and fair trade agreement, enabling a healthy society through communication with elderly living alone or youths without parents, and enhancing marketing strategies. Research design, data, and methodology - To test the hypothesis, a survey was conducted. The surveyed population includes people who use the big three mobile communication services. The survey was conducted from October 4th to October 14th, 2013. A total of 500 survey questionnaires were circulated and 483 were collected; out of these, 32 were excluded due to missing or incomprehensible information. The data was analyzed with SPSS 18.0 via frequency analysis, trust analysis, search factor analysis, relationship analysis, confirmation factor analysis using AMOS 18.0, and structural equation model analysis. Results - Research on corporate social responsibility has been frequently conducted recently. Companies are perceived as social constituents satisfying the social desires of people in addition to customer needs. Further, companies are returning profits to society to satisfy community needs, because there is greater emphasis on the social responsibilities of companies. Companies' social responsibilities should include marketing strategies and the identification of customer needs. This study shows that social service activities influence brand value, which influences customer attitudes; therefore, social service activities indirectly influence customer attitudes. In order to increase customers' purchasing intention, it is essential to improve brand image via social services and provide a distinctive quality of service. Conclusions - This research has used the purposive selection method in the empirical analysis to identify the effect of social services on brand value and customer attitude. Therefore, this study revealed that businesses, whose ultimate objective is to improve customers' purchasing intention, should promote their brand equity through corporate social responsibility activities and offer a distinct service quality. Limitations in the progress of research were found and future indications to overcome these limitations are suggested as follows. First, survey responders had a limited understanding of social responsibilities; therefore, this concept needs to be explained to people first. Second, the research was done on people who live in Daejeon; thus, it is not representative of the entire country. The research has to be repeated with people in other cities. Third, there is a limitation in the study because the purposive selection method was used on Daejeon customers. In the future, a more precise selection of the population is needed. Fourth, Daejeon has unique geographical and size characteristics. Thus, customers in Seoul and other areas may display different characteristics and research on them may reveal different findings. Therefore, again, this study has to be repeated in other areas.

Effects of beta glucan extract from Phellinus baumii on the eusociality of ants (장수상황버섯 베타글루칸 추출물이 개미 집단생활에 미치는 영향)

  • Kim, Ha Won;Lee, Dong-Hee
    • Journal of Mushroom
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    • v.16 no.4
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    • pp.304-310
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    • 2018
  • Beta glucan was purified from Phellinus baumii and tested for its effect on the group performance of ants, a principal model of eusociality and of superorganisms. Japanese carpenter ants (Camponotus japonicus) were reared on diets containing beta glucans to characterize their effects on eusociality. Culturing structures for ants were assembled by implanting autoclaved soil into polyethylene terephthalate bottles. Three different eusocial strength indices were used to study the effect of beta glucan extract (BGE) on eusocial activities - the number of residence chambers, cooperative defense index (CDI), and group size and composition. Control, low- BGE, and high-BGE diets were prepared with the following three levels of BGE supplements in sucrose powder: 0, 20, and 50% (g/g). More residence chambers were observed in the BGE-fed groups than in the control. The CDI against a foreign queen ant was calculated according to the time taken to subdue the foreign queen. The high-BGE group took less time to complete their defense formation than the other groups. Differences were evident between control and BGE-fed groups in the total numbers of ants and eggs. The BGE-fed groups showed a significant increase in both the number of workers and the number of eggs. When fed with BGE, ants responded positively for all three eusocial strength indices. These results show that BGE exerts beneficial effects on the eusociality of ants as a superorganism.

Characteristics of Catalysts System of NGOC-LNT-SCR for CNG Buses (CNG 버스용 NGOC+LNT+SCR 촉매시스템의 특성)

  • Seo, Choong-Kil
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.4
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    • pp.626-631
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    • 2019
  • The policy-making and technological development for the supply expansion of eco-friendly automobiles has been continuing, but the internal combustion engines still accounts for about 95%. Also, in order to meet the stricter emission regulations of internal combustion engines based on fossil fuels, the proportion of after-treatments for vehicles and (ocean going) vessels is gradually increasing. This study is a basic study for the post-Euro-VI exhaust response of CNG buses, and it is to investigate the basic characteristics according to Pd substitution transition metal effect, catalyst volume effect and space velocity. A catalysts was prepared and tested using a model gas reactor. The NGOC catalyst with 3Pd exhibited the highest catalytic activity with 22% at $300^{\circ}C$, 48% at $350^{\circ}C$ and about 75% at $500^{\circ}C$. 3Co NGOC containing 3wt% of transition metal was excellent in oxidation ability, and it was small in size of 2nm, and the degree of catalyst dispersion was improved and de-NO/CO conversion was high. The volume of the NGOC-LNT-SCR catalyst system was optimal in the combination of 1.5+0.5+0.5 with a total score of 165, considering $de-CH_4/NOx$ performance and catalyst cost. For SV $14,000h^{-1}$, the $CH_4$ reduction performance was the highest at about 20%, while the SV $56,000h^{-1}$ was the lowest at about 5%. If the space velocity is small, the flow velocity decreases and the time remaining in the catalyst volume become long, so that the harmful gas was reduced.

Experimental Study on the Effect of the Area Ratio between Shaft and Tunnel and Heat Release Rate on the Plug-holing Phenomena in Shallow Underground Tunnels (저심도 도로터널에서 터널과 수직환기구의 단면적 비와 열방출률이 Plug-holing 현상에 미치는 영향에 관한 실험연구)

  • Hong, Kibea;Na, Junyoung;Ryou, Hong Sun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.4
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    • pp.619-625
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    • 2019
  • It is difficult to design because of the plug-holing phenomenon in which the amount of smoke discharged from the vertical vent is smaller than the designed amount of smoke. In this study, the effect of cross-sectional area ratio of tunnel and natural ventilation and heat release rate of fire source on plug-holing phenomenon occurring in natural ventilation system was experimentally analyzed. In the experiment model reduced to 1/20 size, the aspect ratio of the tunnel and the vertical vent was fixed, and the influence on the plug-holing phenomenon was confirmed by varying the sectional area ratio of the tunnel and the vertical vent. Experimental results show that the plug-holing phenomenon is caused by the comparison of the smoke boundary layer temperature with the temperature in the vertical vents, and the flow and temperature distribution characteristics under the vertical vents are changed as the cross-sectional area ratio of the tunnel and vertical vents increases. The plug-holing phenomenon is affected by the cross-sectional area ratio between the tunnel and the vertical ventilation. The greater the cross-sectional area ratio, the greater the probability of plug-holing.