• Title/Summary/Keyword: size dependent effect

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Pyridoxine Deficiency on Neurotransmitters in the Developing Rat Brain - Catecholamine Metabolism- (Pyridoxine결핍이 뇌의 신경전달물질에 미치는 영향 - Catecholamine 대사 -)

  • Choi, Hay-Mie;Kang, Soon-Ah
    • Journal of Nutrition and Health
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    • v.17 no.3
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    • pp.199-209
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    • 1984
  • Pregnant rats were fed a pyridoxine deficient diet during the gestation and lactation. DEF I group received the deficient diet from delivery ; DEF II group, from the 15 th day of gestation. Body and brain weights, brain protein, DNA, RNA, plasma GOT and GPT, and catecholamines were measured. Effect of MAO inhibiting drug, pargyline, was determined. Brain protein, DNA, and RNA of offsprings of deficient groups were significantly lower than the control group, but RNA/ DNA, brain weight/DNA, and protein/DNA show that cell number were more affected than cell size by the pyridoxine deficiency during the 3rd week of gestation and lactation. Plasma GOT activities were more significantly different than plasma GPT between the control and deficient group. Brain norepinephrine of offsprings of deficient group were significantly lower than the control, but brain dopamine content was not significantly different from the control. At 2nd and 3rd week, norepinephrine was significantly depressed in deficient groups. Pargyline treatment affected a 1.2 fold increase in catecholamines in 3hr while the control had a 1.5 fold increase. Thus norepinephrine and dopamine synthesis was depressed in the deficient groups. Dopaminergic neurons may be less dependent on pyridoxine level than neurons from norepinephrine. Pyridoxine deficiency in maternal diet is not so critical to brain catecholamines of offspring except to the neonatal rats.

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Vortex behavior in the inertial flow of viscoelastic fluids past a confined cylinder

  • Kim, Ju Min;Kim, Chongyoup;Chung, Changkwon;Ahn, Kyung Hyun;Lee, Seung Jong
    • Korea-Australia Rheology Journal
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    • v.16 no.3
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    • pp.117-128
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    • 2004
  • The effect of molecular parameters on the steady vortex behaviors in the inertial viscoelastic flow past a cylinder has been investigated. FENE-CR model was considered as a constitutive equation. A recently developed iterative solution method (Kim et al., (in press)) was found to be successfully applicable to the computation of inertial viscoelastic flows. The high-resolution computations were carried out to understand the detailed flow behaviors based on the efficient iterative solution method armed with ILU(0) type pre-conditioner and BiCGSTAB method. The discrete elastic viscous split stress-G/streamline upwind Petrov Galerkin (DEVSS-G/SUPG) formulation was adopted as a stabilization method. The vortex size decreased as elasticity increases. However, the vortex enhancement was also observed in the case of large extensibility, which means that the vortex behavior is strongly dependent upon the material parameters. The longitudinal gradient of normal stress was found to retard the formation of vortex, whereas the extensional viscosity played a role in the vortex enhancement. The present results are expected to be helpful for understanding the inertial vortex dynamics of viscoelastic fluids in the flow past a confined cylinder.

Vibration analysis of embedded size dependent FG nanobeams based on third-order shear deformation beam theory

  • Ebrahimi, Farzad;Barati, Mohammad Reza
    • Structural Engineering and Mechanics
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    • v.61 no.6
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    • pp.721-736
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    • 2017
  • In this paper, free vibration characteristics of functionally graded (FG) nanobeams embedded on elastic medium are investigated based on third order shear deformation (Reddy) beam theory by presenting a Navier type solution for the first time. The material properties of FG nanobeam are assumed to vary gradually along the thickness and are estimated through the power-law and Mori-Tanaka models. A two parameters elastic foundation including the linear Winkler springs along with the Pasternak shear layer is in contact with beam. The small scale effect is taken into consideration based on nonlocal elasticity theory of Eringen. The nonlocal equations of motion are derived based on third order shear deformation beam theory through Hamilton's principle and they are solved applying analytical solution. According to the numerical results, it is revealed that the proposed modeling can provide accurate frequency results of the FG nanobeams as compared to some cases in the literature. The obtained results are presented for the vibration analysis of the FG nanobeams such as the influences of foundation parameters, gradient index, nonlocal parameter and slenderness ratio in detail.

Effect of Latex Particle Morphology on the Film Properties of Acrylic Coatings (II);Film Forming Behavior of Model Composite Latex (라텍스 입자구조가 필름형성 및 필름물성에 미치는 영향 (II);모델 복합 라텍스 입자의 필름형성 거동)

  • Ju, In-Ho;Wu, Jong-Pyo
    • Journal of the Korean Applied Science and Technology
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    • v.21 no.2
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    • pp.132-139
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    • 2004
  • Film forming behavior of monodispersed model composite latexes with particle size of 190 nm, which consist of n-butyl acrylate as a soft phase monomer and methyl methacrylate as a hard phase monomer with different morphology was examined. Five different types of model latexes were used in this study such as random copolymer particle, soft-core/hard-shell particle, hard-core/soft-shell particle, gradient type particle, and mixed type particle. The film forming behavior was evaluated using pseudo on-line measurements of the cumulative weight loss, the UV transmittance, and the tensile fracture energy. Each stages of film formation I, II were not sensitive to the morphology of model latexes, but stage-ill was largely dependent on the morphology of model latexes. The chain mobility of polymer which composed the shell component was found to dominantly determine the behavior of film forming stage-III.

Effects of Substrate Temperature and the $O_2$/Ar Ratio on the Characteristics of RF Magnetron Sputtered $RuO_2$ Thin Films

  • Park, Jae-Yong;Shim, Kyu-Ha;Park, Duck-Kyun
    • The Korean Journal of Ceramics
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    • v.2 no.1
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    • pp.43-47
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    • 1996
  • $RuO_2$ thin films deposited directly on Si substrate by RF magnetron sputtering method using $RuO_2$ target have been investigated. Special interest was focused on the effect of process parameter on the surface roughness of $RuO_2$ films. Crystallization behavior and electrical properties of the films deposited at $300^{\circ}C$ were superior to those deposited at room temperature. Metallic Ru phase was formed in pure Ar and this phase had resulted poor adhesion after post annealing process in oxidizing ambient. Microstructural analysis reveals that the size of the $RuO_2$ crystallites gets smaller and the surface becomes smoother as the $O_2$ partial pressure or film thickness decreases. Irrespective of the $O_2/Ar$ ratio, resistivity of $RuO_2$ films ranged in $50~70 {\mu}{\Omega}-cm$. As the film thickness decreases, there is a thickness where the resistivity rises abruptly. Such an onset thickness turned out to be dependent n the $O_2$/Ar ratio.

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Effects of Ultrasonic Irradiation on Physical Properties of Silica/PEG Hybrids

  • Jung, Hwa-Young;Gupta, Ravindra K.;Lee, Sang-Ki;Whang, Chin-Myung
    • Journal of the Korean Ceramic Society
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    • v.39 no.2
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    • pp.113-119
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    • 2002
  • The effect of ultrasonic radiation is reported for silica-poly(ethylene glycol) system prepared without the solvent using sol-gel processing by varying various parameters such as ultrasonic irradiation time, PEG content and HCl/TEOS molar ratio. The property of sonogel is compared with classic gel which has been prepared with ethanol as a solvent by traditional sol-gel processing. SEM, BET, DTA-TGA, density and Vickers hardness measurements are carried out for analyzing the samples. The gelation time is found strongly dependent on radiation time, PEG content and pH value, and has been discussed on the basis of existing theories. The $SiO_2-10$ & 20 wt% PEG sonogel exhibited superior optical, physical and gel properties as compared to the classic gel, hence, found suitable for device applications. The ultrasonic radiation increased the density and surface area, and also reduced the pore size which is well supported by the shift in the peak of DTA curve. The DTA thermogram was found similar to that of pure silica gel.

A Study on the Financing Decision of Korean Private Hospitals (우리나라 민간병원의 자본조달결정에 관한 연구)

  • Choi, Man-Kyu
    • Korea Journal of Hospital Management
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    • v.7 no.3
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    • pp.25-43
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    • 2002
  • This study focuses on the factors that make the financing decision of private hospitals in Korea. Data used in this study were collected from 98 hospitals with complete general data of current status as well as financial statements. They were chosen from the 138 hospitals that passed the accreditation process by the Korean Hospital Association from 1996 to 2000 for the purpose of accrediting training hospitals. The dependent variables in this study consist of total liabilities to total assets, borrowings to total assets. The independent variables are ownership, hospital type, teaching status, location, bed size, period of establishment, asset structure, profitability, growth, tax shields, volatility of profit, competition(market concentration), and other factors. The major findings of this study are as follows. The factors found to have significant effect on liabilities to total assets are teaching status(-), asset structure(-), profitability(-), tax shields(+), and business risk(-). University hospitals have less liabilities than the non-university hospitals. It was also confirmed that high profitability, high fixed asset, high volatility of profit and low tax shields results in decrease in liabilities. The factors that significantly affect on borrowings to total assets are teaching status(-), period of establishment(-), volatility of profit(-) and competition(+).

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Ameliorating Effect of Mycoleptodonoides aitchisonii on High-fat Diet-induced Obese Mice

  • Lee, Mi Ra;Begum, Shahnaz;Oh, Deuk Sil;Wee, An Jin;Yun, Byung Sun;Sung, Chang Keun
    • Preventive Nutrition and Food Science
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    • v.19 no.2
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    • pp.69-74
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    • 2014
  • The present study investigated the anti-obesity effects of Mycoleptodonoides aitchisonii (MA) in mice fed a high-fat (HF) diet. Two groups were fed either a normal control diet or an HF (45% kcal fat) diet for 12 weeks and three groups were fed an HF diet supplemented with powdered MA (MAP, 1%, 3%, and 5%) for 12 weeks. The anti-obesity effects of MAP supplementation on body weight, fat mass development, and lipid-related markers were assessed. Consumption of an HF diet resulted in increased body weight, serum lipids, relative adipose tissues weight, and liver fat accumulation. However, administration of MAP significantly decreased body weight gain, food intake, food efficiency ratio, hepatic cholesterol level, and adipose tissue weight in a dose-dependent manner. In addition, treatment with MAP significantly reduced the occurrence of fatty liver deposits and steatosis, and inhibited an HF diet-induced increase in adipocyte size. These results suggest that dietary supplementation with MAP exerts anti-obesity effects and indicate that MAP could be used as a functional food to control obesity.

An Experimental Study on Boiling Heat Transfer of PF5060 on the Shape and Orientation of Micro-Fin Surfaces (마이크로휜 표면과 발열체 기울기에 따른 PE5060의 비등 열전달에 관한 실험적 연구)

  • Kim Yoon-Ho;Kim Choong;Lee Kyu-Jung;Kim Youngchan
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.30 no.1 s.244
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    • pp.74-81
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    • 2006
  • Experiments to measure the pool boiling heat transfer on the micro-fin surfaces were performed with PF5060. The effects of various orientation and subcooling of heat surface on pool boiling performance were investigated under various heat-flux conditions for plain and micro-fin surfaces. The comparison between the results of this study and those of previous work shows a similar trend at the same conditions. From the results, it is proved that nucleate boiling performance is strongly dependent on the orientation, the micro-fin structure and the subcooling of heat surface. The heat flux on the surface with orientation angles of $45^{\circ}$ and $90^{\circ}$ was larger than that on horizontal surface(${\theta}=0^{\circ}$) at same wall superheat because of the effect of bubble sweeping. The nucleate boiling performance of micro-fin surfaces is enhanced by decreasing the fin size(WxL) and the pitch, respectively. The subcooling makes nucleate boiling performance lower for both micro-fin and plain surfaces.

Biological Control of Apple Anthracnose by Paenibacillus polymyxa APEC128, an Antagonistic Rhizobacterium

  • Kim, Young Soo;Balaraju, Kotnala;Jeon, Yongho
    • The Plant Pathology Journal
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    • v.32 no.3
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    • pp.251-259
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    • 2016
  • The present study investigated the suppression of the disease development of anthracnose caused by Colletotrichum gloeosporioides and C. acutatum in harvested apples using an antagonistic rhizobacterium Paenibacillus polymyxa APEC128 (APEC128). Out of 30 bacterial isolates from apple rhizosphere screened for antagonistic activity, the most effective strain was APEC128 as inferred from the size of the inhibition zone. This strain showed a greater growth in brain-heart infusion (BHI) broth compared to other growth media. There was a reduction in anthracnose symptoms caused by the two fungal pathogens in harvested apples after their treatment with APEC128 in comparison with non-treated control. This effect is explained by the increased production of protease and amylase by APEC128, which might have inhibited mycelial growth. In apples treated with different APEC128 suspensions, the disease caused by C. gloeosporioides and C. acutatum was greatly suppressed (by 83.6% and 79%, respectively) in treatments with the concentration of $1{\times}10^8$ colony forming units (cfu)/ml compared to other lower dosages, suggesting that the suppression of anthracnose development on harvested apples is dose-dependent. These results indicated that APEC128 is one of the promising agents in the biocontrol of apple anthracnose, which might help to increase the shelf-life of apple fruit during the post-harvest period.