• Title/Summary/Keyword: size dependent effect

Search Result 640, Processing Time 0.033 seconds

Meta-Analysis of the Effect of Diabetes Intervention Programs for Korean Adults with Type 2 Diabetes (한국 성인 2형 당뇨병 환자를 위한 당뇨 중재 프로그램 효과에 대한 메타 분석)

  • Park, Mi-Young;Kim, Joungmin
    • The Korean Journal of Food And Nutrition
    • /
    • v.35 no.3
    • /
    • pp.193-203
    • /
    • 2022
  • This study aimed to provide directions and implications for a future program by analyzing studies on diabetes programs from 2000 to 2020. Among the studies with control and experimental groups, the selected studies included ones that provided intervention to patients with diabetes and ones that contained descriptive statistics. Sixteen studies were selected to verify the effectiveness and homogeneity of the data coding meta-analysis. The overall effect size in the diabetes program combined estimate was 0.398 (95% CI: 0.268, 0.425, p=0.000). Among the dependent variables, fasting blood glucose (-0.616) and glycated hemoglobin (-0.442) showed median effect sizes, but the effect of fasting blood glucose was not statistically significant. In terms of the study design, non-randomized control trials (NRCTs) (-0.543) was more effective than randomized control trials (RCTs) (0.719). Among, the counseling and self-management program (-3.241) showed a very large effect size. Furthermore, the cognitive-behavioral (-0.828) and self-management (-0.482) programs were also found to have a positive effect on lowering fasting blood glucose. As the importance of diabetes management increases, further studies based on RCT should be actively performed, and differentiated and specialized diabetes intervention plans need to be established.

An In-silico Simulation Study on Size-dependent Electroelastic Properties of Hexagonal Boron Nitride Nanotubes (인실리코 해석을 통한 단일벽 질화붕소 나노튜브의 크기 변화에 따른 압전탄성 거동 예측연구)

  • Jaewon Lee;Seunghwa Yang
    • Composites Research
    • /
    • v.37 no.2
    • /
    • pp.132-138
    • /
    • 2024
  • In this study, a molecular dynamics simulation study was performed to investigate the size-dependent electroelastic properties of single-walled boron nitride nanotubes(BNNT). To describe the elasticity and polarization of BNNT under mechanical loading, the Tersoff potential model and rigid ion approximation were adopted. For the prediction of piezoelectric constants and Young's modulus of BNNTs, piezoelectric constitutive equations based on the Maxwell's equation were used to calculate the strain-electric displacement and strain-stress relationships. It was found that the piezoelectric constants of BNNTs gradually decreases as the radius of the tubes increases showing a nonnegligible size effect. On the other hand, the elastic constants of the BNNTs showed opposites trends according to the equivalent geometrical assumption of the tubular structures. To establish the structure-property relationships, localized configurational change of the primarily bonded B-N bonded topology was investigated in detail to elucidate the BNNT curvature dependent elasticity.

The Parametric Influence on Focused Ion Beam Processing of Silicon (집속이온빔의 공정조건이 실리콘 가공에 미치는 영향)

  • Kim, Joon-Hyun;Song, Chun-Sam;Kim, Jong-Hyeong;Jang, Dong-Young;Kim, Joo-Hyun
    • Transactions of the Korean Society of Machine Tool Engineers
    • /
    • v.16 no.2
    • /
    • pp.70-77
    • /
    • 2007
  • The application of focused ion beam(FIB) technology has been broadened in the fabrication of nanoscale regime. The extended application of FIB is dependent on complicated reciprocal relation of operating parameters. It is necessary for successful and efficient modifications on the surface of silicon substrate. The primary effect by Gaussian beam intensity is significantly shown from various aperture size, accelerating voltage, and beam current. Also, the secondary effect of other process factors - dwell time, pixel interval, scan mode, and pattern size has affected to etching results. For the process analysis, influence of the secondary factors on FIB micromilling process is examined with respect to sputtering depth during the milling process in silicon material. The results are analyzed by the ratio of signal to noise obtained using design of experiment in each parameter.

Effect of sulfuric acid hydrolysis condition on yield, particle size and surface charge of cellulose nanocrystals (황산 가수분해 조건이 셀룰로오스 나노크리스탈의 수율, 입도 및 전기화학적 특성에 미치는 영향)

  • Ryu, Jae-Ho;Youn, Hye-Jung
    • Journal of Korea Technical Association of The Pulp and Paper Industry
    • /
    • v.43 no.4
    • /
    • pp.67-75
    • /
    • 2011
  • Sulfuric acid hydrolysis is a typical approach for producing cellulose nanocrystals. The method has been widely used, but it has a disadvantage of low yield of cellulose nanocrystals compared to mechanical method. To expand the application of cellulose nanocrystals in practical, we should be able to produce them with higher yield and the controlled properties. In this study, therefore, we intended to investigate the effect of sulfuric acid hydrolysis condition on the characteristics of the prepared cellulose nanocrystals. The concentration of sulfuric acid, temperature and hydrolysis time were varied, and the yield as well as diverse properties including the morphology, size and zeta potential were examined. We could obtain cellulose nanocrystals up to 70% of yield and found that the properties were dependent on the reaction condition. It would be helpful to select an appropriate condition for producing cellulose nanocrystals.

Effect of Austenite Grain Size on Ms temperature of γ→ε Martensitic Transformation in an Fe-Mn Alloy (Fe-Mn 합금에서 γ→ε 마르텐사이트 변태의 Ms 온도에 미치는 오스테나이트 결정립크기의 영향)

  • Jun, Joong-Hwan;Choi, Chong-Sool
    • Journal of the Korean Society for Heat Treatment
    • /
    • v.10 no.2
    • /
    • pp.93-100
    • /
    • 1997
  • Effect of austenite grain size on starting temperature of ${\gamma}{\rightarrow}{\varepsilon}$ martensitic transformation($M_s$) has been studied in an Fe-18%Mn alloy. Particular attention was paid on the variation of stacking fault energy with austenite grain size, which is considered to be a important factor affecting ${\gamma}{\rightarrow}{\varepsilon}$ martensitic transformation. Austenite grain size was increased in a wide range from $13{\mu}m$ to $185{\mu}m$ with increasing solution treatment temperature from $700^{\circ}C$ to $1100^{\circ}C$. Hardness was decreased with increasing austenite grain size while the volume fraction of ${\varepsilon}$ martensite showed a reverse tendency, which indicates that the hardness is more dependent on austenite grain size than ${\varepsilon}$ martensite content. No significant change was found in $M_s$ temperature when the grain size was larger than about $30{\mu}m$. In case that, the austenite grain size was smaller than about $30{\mu}m$, however, $M_s$ temperature was marlkedly decreased with decreasing austenite grain size. A linear relationship between $M_s$ temperature and the stacking fault formation probability, i.e. the reciprocal of the stacking fault energy was obtained, which suggests that the variation of $M_s$ temperature with austenite grain size is closely related to the change in stacking fault energy.

  • PDF

Experimental Studies on the Effect of Gamibaegi-eum

  • Kim Won-Ill
    • The Journal of Korean Medicine
    • /
    • v.25 no.4
    • /
    • pp.61-78
    • /
    • 2004
  • Objective : This study was undertaken to determine whether Gamibaegi-eum (BGU) in vitro and in vivo exerts a beneficial effect against cell injury induced by reactive oxygen species (ROS) in the human intestine. Methods : Effects of BGU in vitro on cell injury were examined using Caco-2 cells, cultured human intestinal cell line. Exposure of cells to H₂O₂ induced increases in the loss of cell viability in a time and dose-dependent fashion. Results : BGU prevented H₂O₂-induced cell death and its effect was dose-dependent over a concentration range of 0.05­1%. H₂O₂-induced cell death was prevented by catalase, the hydrogen peroxide scavenger enzyme, and deferoxamine, the iron chelator. However, the potent antioxidant DPPD did not affect H₂O₂-induced cell death. H₂O₂ increased lipid peroxidation, which was inhibited by BGU and DPPD. H₂O₂ caused DNA damage in a dose-dependent manner, which was prevented by BGU, catalase, and deferoxamine, but not DPPD. BGU restored ATP depletion induced by H₂O₂. BGU inhibited generation of superoxide and H₂O₂ and scavenged directly H₂O₂. Oral administration of mepirizole in vivo at a dose of 200mg/kg resulted in ulcer lesions in the stomach and the proximal duodenum. Pretreatment of BGU(0.1%/kg, orally) and catalase (800Units/kg, i.v.) significantly decreased the size of ulcers. Mepirizole increased lipid peroxidation in the mucosa of the duodenum, suggesting an involvement of ROS. Pretreatment of BGU and catalase significantly inhibited lipid peroxidation induced by mepirizole. Morphological studies showed that mepirizole treatment causes duodenal injury and its effect is prevented by BGU. Conclusion : These results indicate that BGU exerts a protective effect against cell injury in vitro and in vivo through antioxidant action. The present study suggests that BGU may playa therapeutic role in the treatment of human gastrointestinal diseases mediated by ROS.

  • PDF

Influences of Particle Property and Its Size Impact Damage and Strength Degradation in Silicon Carbide Ceramics (탄화규소 세라믹의 충격손상 및 강도저하에 미치는 입자의 재질 및 크기의 영향)

  • 신형섭;전천일랑;서창민
    • Transactions of the Korean Society of Mechanical Engineers
    • /
    • v.16 no.10
    • /
    • pp.1869-1876
    • /
    • 1992
  • The effect of particle property on FOD(foreign object damage) and strength degradation in structural ceramics especially, silicon carbide was investigated by accelerating a spherical particle having different material and different size. The damage induced showed significant differences in their patterns with increase of impact velocity. Also percussion cone was formed at the back part of specimen when particle size became large and its impact velocity exceeded a critical value. The extent of ring cracks was linearly related to particle size, however the impact of steel particle produced larger ring cracks than that of SiC particle. Increasing impact velocity the residual strength showed different degradation behaviors according to particle and its size. In the region the impact site represents nearly elastic deformation behavior, the residual strength was dependent upon the depth of cone crack regardless of particle size. However in elastic- plastic deformation region, the radial cracks led to rapid drop in residual strength.

Particle Size, Morphology and Color Characteristics of C.I. Pigment Red 57:1 : 1. Effect of Synthesis Conditions

  • Seo, Hee Sung;Lee, Hyun Kyung;Yoo, Eui Sang
    • Textile Coloration and Finishing
    • /
    • v.27 no.4
    • /
    • pp.229-244
    • /
    • 2015
  • The effects of synthesis conditions on characteristics of the calcium-azo complex pigment, C.I. Pigment Red 57:1, were studied. It was mainly considered that the industrially required synthesis conditions for lowering electrical conductivity of the pigment solution keeping pigment quality such as particle size and color characteristics. Three parameters were chosen as control factors during the synthesis. The first was the amount of hydrochloric acid added to transform sodium nitrite into nitrous acid. The second was the amount of calcium chloride added to insolubilize the synthesized azo dye. The final factor was pH control during the coupling reaction. The electrical conductivity and pigment aggregate particle size were dependent on the amount of hydrochloric acid and calcium chloride. Higher HCl concentration gave brighter yellowish-red color because of smaller particle aggregate size and narrower size distribution. Amount of charged ions in the synthesis process might affect the "lake" formation resulting different particle aggregate size and color shade.

Affective Design for the Frame Size and Shape of Wide LCD Monitors (Wide LCD 모니터의 프레임 형태에 따른 감성 선호도 연구)

  • Lee, Han-Na;Jung, Eui-S.;Choe, Jae-Ho
    • Journal of the Ergonomics Society of Korea
    • /
    • v.28 no.4
    • /
    • pp.61-69
    • /
    • 2009
  • With increasing needs for affective design, it became an essential part in a product development process to look up quantitative ergonomic data that reflects customers' preferences on design factors in various products. This study looked at wide LCD monitors and analyzed customers' affective preferences regarding monitor's bezel frame size and shape. The monitor's bezel frame depth, size and ratio were selected as independent variables among many design parameters. As dependent variables, customer's subjective preferences were measured. A statistical analysis revealed that monitor's bezel frame depth, size and ratio had significant effects on customer's preferences. Also, it was possible to find a different tendency on affective variables and their levels for 19" and 24" wide LCD monitors. In general, experiments revealed that customers reacted more sensitively in 24" wide LCD monitors to all variables. In 19" wide LCD monitors, only the lower frame bezel size had a significant effect, otherwise, lower, upper and side frame bezels appeared to be effective variables in 24" monitors. In order to reflect customer's affective preferences to new design of wide LCD monitors, this study is expected to provide quantitative ergonomic data and guidelines for the design of wide LCD monitor's bezel frame depth and size.

The Meta-Analysis on Effects of Arduino-Based Education for Secondary School Students (중·고등학생 대상 아두이노 활용 교육의 효과에 대한 메타분석)

  • Jang, Bong Seok
    • Journal of Industrial Convergence
    • /
    • v.19 no.3
    • /
    • pp.61-65
    • /
    • 2021
  • This study aimed to analyze effects of Arduino-based education for secondary school students through meta-analysis. Prior studies including journal articles and theses were selected through rigorous review. The researcher calculated the overall effect size and effect sizes by categorical variables. Research findings are as follows. First, the total effect size of Arduino-based education was 0.537. Second, the effect sizes by type of dependent variables were the affective domain 0.849 and the cognitive domain 0.479. Third, the effect sizes by school level were the middle school 0.796 and the high school 0.474. Fourth, the effect sizes by subject areas were music 1.255, science 0.562, technology 0.443, and information 0.429. Fifth, the effect sizes by types of programming were the graphic-based programming 0.543 and the text-based programming 0.376.