• 한국신재생에너지학회:학술대회논문집
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• 2005.06a
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• pp.701-704
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• 2005

Aquifer Thermal Energy Storage (ATES) can be a cost-effective and renewable geothermal energy source, depending on site-specific and thermohydraulic conditions. To design an effective ATES system having influenced by groundwater movement, understanding of thermo hydraulic processes is necessary. The heat transfer phenomena for an aquifer heat storage are simulated using FEFLOW with the scenario of heat pump operation with pumping and waste water reinjection in a two layered confined aquifer model. Temperature distribution of the aquifer model is generated, and hydraulic heads and temperature variations are monitored at the both wells during 365 days. The average groundwater velocities are determined with two hydraulic gradient sets according to boundary conditions, and the effect of groundwater flow are shown at the generated thermal distributions of three different depth slices. The generated temperature contour lines at the hydraulic gradient of 0.00 1 are shaped circular, and the center is moved less than 5m to the groundwater flow direction in 365 days simulation period. However at the hydraulic gradient of 0.01, the contour center of the temperature are moved to the end of boundary at each slice and the largest movement is at bottom slice. By the analysis of thermal interference data between two wells the efficiency of the heat pump system model is validated, and the variation of heads is monitored at injection, pumping and no operation mode.

• Korean System Dynamics Review
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• v.7 no.1
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• pp.147-172
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• 2006

With the purpose of long-range planning toward local/regional sustainable development, it is desired to avoid unconditional industrialization and expansion and to build an eco-oriented development strategy considering site-specific characteristics of the environment. This paper thus aims at the elaboration of a system dynamics model of a locality/region so as to understand inherent dynamics of sustainable development and to assess the effectiveness of such an eco-oriented strategy. The model thus consists of several positive and negative feedback loops that accelerate or restrict local/regional economic growth within a system boundary incorporating the environment, economy, and society. The model is moreover applied to the assessment of the effectiveness of the development plan recently established in Damyang in JeollaNamdo, Korea. It is regarded in this case to be effective for population immigration and economic prosperity to give priority to restore the bamboo ecosystem and nourish a series of eco-friendly industries based on the bamboo items developed recently. It is also to be positive to sustainable development since it enables to maintain high quality of the environment from the outset of their development steps.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2005.09a
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• pp.249-255
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• 2005

Angiotensin-converting enzyme (ACE) is primarily responsible for human hypertension. Current ACE drugs show serious cough and angiodema health problems due to the un-specific activity of the drug to ACE protein. The availability of ACE crystal structure (1UZF) provided the plausible biological orientation of inhibitors to ACE active site (C-domain). Three-dimensional quantitative structure-activity relationship (3D-QSAR) models have been constructed using the comparative molecula. field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) for a series of 28 ACE inhibitors. Alignment for CoMFA obtained by docking ligands to 1UZF protein using FlexX program showed better statistical model as compared to superposition of corresponding atoms. The statistical parameters indicate reasonable models for both CoMFA (q$^2$ = 0.530, r$^2$ = 0.998) and CoMSIA (q$^2$= 0.518, r$^2$ = 0.990). The 3D-QSAR analyses provide valuable information for the design of ACE inhibitors with potent activity towards C-domain of ACE. The group substitutions involving the phenyl ring and carbon chain at the propionyl and sulfonyl moieties of captopril are essential for specific activity to ACE.

• Journal of Biosystems Engineering
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• v.39 no.4
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• pp.377-388
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• 2014

Purpose: Determining the spatial structure of data is important in understanding within-field variability for site-specific crop management. An understanding of the spatial structures present in the data may help illuminate interrelationships that are important in subsequent explanatory analyses, especially when site variables are correlated or are a combined response to multiple causative factors. Methods: In this study, correlation, principal component analysis, and single and nested variogram models were applied to soil electrical conductivity and chemical property data of two fields in central Missouri, USA. Results: Some variables that were highly correlated, or were strongly expressed in the same principal component, exhibited similar spatial ranges when fitted with a single variogram model. However, single variogram results were dependent on the active lag distance used, with short distances (30 m) required to fit short-range variability. Longer active lag distances only revealed long-range spatial components. Nested models generally yielded a better fit than single models for sensor-based conductivity data, where multiple scales of spatial structure were apparent. Gaussian-spherical nested models fit well to the data at both short (30 m) and long (300 m) active lag distances, generally capturing both short-range and long-range spatial components. As soil conductivity relates strongly to profile texture, we hypothesize that the short-range components may relate to the scale of erosion processes, while the long-range components are indicative of the scale of landscape morphology. Conclusion: In this study, we investigated the effect of changing active lag distance on the calculation of the range parameter. Future work investigating scale effects on other variogram parameters, including nugget and sill variances, may lead to better model selection and interpretation. Once this is achieved, separation of nested spatial components by factorial kriging may help to better define the correlations existing between spatial datasets.

• Korean Journal of Ecology and Environment
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• v.44 no.2
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• pp.214-225
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• 2011

The objectives of the study were to evaluate seasonal patterns of epilimnetic water quality, and determine interannual eutrophication patterns at the dam site of Yong-dam Reservoir using long-term data during 2002~2009. Ionic dilutions, based on specific conductivity, occurred in the summer period in response to the intense monsoon rain and inflow, and suspended solid analysis indicated that the reservoir was clear except for the monsoon. Seasonality of nitrogen contents varied depending on the types of nitrogen and responded to ionic dilution; Ammonia-nitrogen ($NH_4$-N) peaked at dry season but nitrate-nitrogen ($NO_3$-N) peaked in the monsoon when the ionic dilution occurred. The maxima of $NO_3$-N seemed to be related with external summer N-loading from the watershed and active nitrogen fixation of bluregreens in the summer. $NO_3$-N was major determinant (>50%) of the total nitrogen pool and relative proportion of $NH_4$-N was minor. Long-term annual $NO_3$-N and TDN showed continuous increasing trends from 2004 to 2009, whereas TP and TDP showed decreasing trends along with chlorophyll-a (CHL) values. Empirical model analysis of log-transformed nutrients and N : P ratios on the CHL showed that the reservoir CHL had a stronger linear function with TP ($R^2$=0.89, p<0.001) than TN ($R^2$=0.35, p=0.120). Overall results suggest that eutrophication progress, based on TP and CHL, is slow down over the study period and this was mainly due to reduced phosphorns, which is considered as primary nutrient by the empirical model.

• The Transactions of the Korea Information Processing Society
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• v.2 no.5
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• pp.645-654
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• 1995

A distributed DBMS integrates local schemas that are independently designed, maintained, and managed by different users at each site providing a global virtual schema. This global schema supports users at a specific site to transparently utilize local database at different sites. The security features of the local schema should also not be changed in the global schema integrating security features of each local schema. Researches on the integration of security features into local schema in distributed DBMS environment, however, are very rate. This pater using the multilevel secure object-oriented database model(as the model for the definition of a local schema in distributed environment) which is an extension of the object-oriented models. It also suggests eight integration methods that can maintain the security features of local schemas. The eight methods are classified by the object classes and by relationships among them.

• Korean Journal of Agricultural and Forest Meteorology
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• v.6 no.4
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• pp.235-241
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• 2004

There is a growing concern about the possible increase in inter-annual variation of minimum temperature during the winter season in Korea. This view is strengthened by frequently reported freezing injury to dormant fruit trees, while warmer winters have prevailed recently. The January minimum temperature record at fourteen weather stations was analyzed for 1951-2000. The results showed no evidence of increasing standard deviation at 3 locations between 1951-1980 and 1971-2000, while the remaining 11 stations showed a trend of decreasing standard deviation for the two periods. An empirical model explaining the spatial variation of the standard deviation was derived by regression analysis of 56 stations' data for 1971-2000. Daily minimum temperature and the site elevation may account for 68% of the observed variations. We applied this model to restore the average standard deviation of the January minimum temperature for 1971-2000, and the result was used to produce gridded minimum temperature data for the recurrence interval of 10 and 30 years at 250m resolution. A digital form of the plant hardiness zone map may be developed from this product for site-specific selection of adapted plant species.

• Molecules and Cells
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• v.27 no.6
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• pp.651-656
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• 2009

The formation of ${\beta}$-amyloid peptide ($A{\beta}$) is initiated from cleavage of amyloid precursor protein (APP) by a family of protease, ${\alpha}$-, ${\beta}$-, and ${\gamma}$-secretase. Sub W, a substrate peptide, consists of 10 amino acids, which are adjacent to the ${\beta}$-cleavage site of wild-type APP, and Sub M is Swedish mutant with double mutations on the left side of the ${\beta}$-cleavage site of APP. Sub W is a normal product of the metabolism of APP in the secretary pathway. Sub M is known to increase the efficiency of ${\beta}$-secretase activity, resulting in a more specific binding model compared to Sub W. Three-dimensional structures of Sub W and Sub M were studied by CD and NMR spectroscopy in water solution. On the basis of these structures, interaction models of ${\beta}$-secretase and substrate peptides were determined by molecular dynamics simulation. Four hydrogen bonds and one water-mediated interaction were formed in the docking models. In particular, the hydrogen bonding network of Sub M-BACE formed spread over the broad region of the active site of ${\beta}$-secretase (P5-P3'), and the side chain of P2- Asn formed a hydrogen bond specifically with the side chain of Arg235. These are more favorable to the cleavage of Sub M by ${\beta}$-secretase than Sub W. The two substrate peptides showed different tendency to bind to ${\beta}$-secretase and this information may useful for drug development to treat and prevent Alzheimer's disease.

• Environmental Engineering Research
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• v.12 no.4
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• pp.176-193
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• 2007

The ability to measure groundwater contaminant flux is increasingly being recognized as crucial in order to prioritize contaminated site cleanups, estimate the efficiency of remediation technologies, measure rates of natural attenuation, and apply proper source terms to model groundwater contaminant transport. Recently, a number of methods have been developed and subsequently applied to measure contaminant mass flux in groundwater in the field. Flux measurement methods can be categorized as either point methods or integral methods. As the name suggests, point methods measure flux at a specific point or points in the subsurface. To increase confidence in the accuracy of the measurement, it is necessary to increase the number of points (and therefore, the cost) of the sampling network. Integral methods avoid this disadvantage by using pumping wells to interrogate large volumes of the subsurface. Unfortunately, integral methods are expensive because they require that large volumes of contaminated water be extracted and managed. Recent work has investigated the development of an integral method that does not require extraction of contaminated water from the subsurface. We begin with a review of the significance and importance of measuring groundwater contaminant mass flux. We then review groundwater contaminant flux measurement methods that are either currently in use or under development. Finally, we conclude with a qualitative comparison of the various flux measurement methods.

• Korean Institute of Interior Design Journal
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• no.3
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• pp.26-32
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• 1994

The aim of this study is to provide practical guide for exterior design in apartment and to propose a device to improve the quality of residential environment by the color planning. Color is a language of context and used as a visual aid to recognize the objects and spaces in the world around us. In this sense, each color perception is unique to its own setting and not subject to any universal rules of thumbs, Therefore, when designing with color, each setting will demand its own specific set of rules. A balanced color scheme has to make the environment more pleasant for people to live in . Fro the exterior in housing the use of color has to be considered not just in its wider context of the architecture or surrounding but as an element of the life of the inhabitant. So it is considered on the type of people who will live in and visual condition of site. In this study , the objective model of systematic design process for environmental color planning is proposed on the basis of theroetical background and references investigated, By the existing thesis, resident's preference of the exterior color and foumular of composition in apartment was invastigated . In general theories, based on the theory Birren's color harmony for color coordination an design principles, a device of exterior color design in apartment was suggested by the course of reasonable design process. Color in environment plays many different roles. It integrates the architecture with the site. If color is use well, it can soften architecture that is too harsh, it can give a sense of identity to different part of site and improve a city's image. The environmental color is effective media to enhance the aesthetic value of architecture and environment.