• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.4
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• pp.759-768
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• 2015

The ground motions of large dimensional structures such as long span bridges at different stations during an earthquake, are inevitably different, which is known as the ground motion spatial variation effect. There are many causes that may result in the spatial variability in seismic ground motion, e.g., the wave passage effect due to the different arrival times of waves at different locations; the loss of coherency due to seismic waves scattering in the heterogeneous medium of the ground; the site amplification effect owing to different local soil properties. In previous researches, the site amplification effects have not been considered or considered by a single-layered soil model only. In this study, however, the ground motion amplification and filtering effects are evaluated by multi-layered soil model. Spatially varying ground motion at the sites with different number of layers, depths, and soil characteristics are generated and the variation characteristics of ground motion time histories according to the correlation of coherency loss function and soil conditions are evaluated. For the bridge system composed of two unit bridges, seismic behavior characteristics are analyzed using the generated seismic waves as input ground motion. Especially, relative displacement due to coherency loss and site effect which can cause the unseating and pounding between girders are evaluated. As a result, considering the soil conditions of each site are always important and should not be neglected for an accurate structural response analysis.

• Journal of Nutrition and Health
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• v.28 no.10
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• pp.1031-1039
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• 1995

Dietary mehaden oil enhances mucosal hyperplasia that normally occurs after massive small bowel resection. In contrast, dexamethasone and aspirin inhibit the adaptation response. In order to gain insight on the mechanism of these effects, male Sprague-Dawley rats weighing approximately 150gram were randomly divided into two groups and fed diet containing either 15% safflower oil or 14% menhaden oil and 1% safflower oil. Ten days later they were subjected to 70% jejunoilear resection. Immediately after surgery each group was further divided into two groups and receive either vehicle or 125ug/kg/day dexamethasone subcutaneously. All animals were sacrificed seven days after the surgery, and the remaining intestine was removed and divided at the anastomotic site. Dexamethasone, which decreased gut hyperplasia in both dietary groups, decreased both serum IGF-I levels and ileral PGE2 synthesis. Menhaden oil enhanced gut hyperplasia, but did not increase IGF-I or IGF-II levels in serum. PGE2 synthesis was lower in the ileum of menhaden oil-fed rats compared to that of safflower oil-fed rats. The effects of menhaden oil on adaptation did not apper to be mediated either through IGFs or PGE2 synthesis. Other factors could have played a role in enhancing adaptation following menhaden oil feeding.

• International Journal of Advanced Culture Technology
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• v.11 no.3
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• pp.346-357
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• 2023

The purpose of this study is to suggest improvement plans for prevention regulations by reflecting the toxicity, fire and explosion effects of hazardous materials factories and surrounding areas using an off-site consequence assessment program. Regarding the effects of the hydrogen cyanide leak accident, which is the 1st petroleum of the 4th class flammable liquid, Areal Locations of Hazardous Atmospheres (ALOHA) program was used to compare and analyze the extent of damage effects for toxicity, overpressure, and radiation. As a result, the toxicity was analyzed to exceed 5km in the area with Acute exposure guideline level (AEGL)-2 concentration or higher, the overpressure was 103m in the range of 1 psi or more, and the radiant heat was analyzed to be 724m in the range of 2kw/m² or more. Toxicity and radiation affected the area outside the hazardous material storage area, but the overpressure was limited to the inside of the hazardous material storage area. Therefore, we propose to improve the safety management of hazardous materials by conducting a risk assessment for hazardous materials and reflecting the results in internal and external emergency response plans to prepare prevention regulations.

• Smart Structures and Systems
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• v.16 no.2
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• pp.263-280
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• 2015

Microwave remote sensing is probably the most recent experimental technique suitable to the non-contact measurement of deflections on large structures, in static or dynamic conditions. In the first part of the paper, the main techniques adopted in microwave remote sensing are described, so that advantages and potential issues of these techniques are presented and discussed. Subsequently, the paper addresses the application of the radar technology to the measurement of the vibration response on the stay cables of two cable-stayed bridges. The dynamic tests were performed in operational conditions (i.e. with the excitation being mainly provided by micro-tremors, wind and traffic) and the maximum deflections of the cables were generally lower than 5.0 mm. The investigation clearly highlights: (a) the safe and simple use of the radar on site and its effectiveness to simultaneously measure the dynamic response of all the stay cables of an array; (b) the negligible effects of the typical issues and uncertainties that might affect the radar measurements; (c) the accuracy of the results provided by the microwave remote sensing in terms of natural frequencies and tension forces of the stay cables; (d) the suitability of microwave interferometry to the repeated application within Structural Health Monitoring programmes.

• Earthquakes and Structures
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• v.12 no.1
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• pp.91-108
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• 2017

Superstructures and isolation systems of seismically isolated buildings located close to active faults may observe increased seismic demands resulting from long-period and high-amplitude velocity and displacement pulses existent in near-fault ground motions as their fundamental periods may be close to or coincident with these near-fault pulse periods. In order to take these effects into account, the 1997 Uniform Building Code (UBC97) has specified near-source factors that scale up the design spectrum depending on the closest distance to the fault, the soil type at the site, and the properties of the seismic source. Although UBC97 has been superseded by the 2015 International Building Code in the U.S.A., UBC97 near-source factors are still frequently referred in the design of seismically isolated buildings around the world. Therefore it is deemed necessary and thus set as the aim of this study to assess the necessity and the adequacy of near-source factors for seismically isolated buildings. Benchmark buildings of different heights with isolation systems of different properties are used in comparing seismic responses obtained via time history analyses using a large number of historical earthquakes with those obtained from spectral analyses using the amplified spectrums established through UBC97 near-source factors. Results show that near-source factors are necessary but inadequate for superstructure responses and somewhat unconservative for base displacement response.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.23 no.2
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• pp.95-102
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• 2011

A ground loop heat exchanger in a ground source heat pump system is an important unit that determines the thermal performance of a system and its initial cost. A proper design requires certain site specific parameters, most importantly the ground effective thermal conductivity, the borehole thermal resistance and the undisturbed ground temperature. This study was performed to investigate the effect of some parameters such as borehole lengths, various grouting materials and U tube configurations on ground effective thermal conductivity and borehole thermal resistance. In this study, thermal response tests were conducted using a testing device to 9 different ground loop heat exchangers. From the experimental results, the length of ground loop heat exchanger affects to the effective thermal conductivity. The results of this experiment shows that higher thermal conductivity of grouting materials leads to the increase effective thermal conductivity from 22 to 32%. Also, mounting spacers have increased by 14%.

• The Korean Journal of Physiology and Pharmacology
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• v.5 no.1
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• pp.93-98
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• 2001

The precise mechanism of set-point regulation in hypothalamus was not elucidated. Nitric oxide synthases(NOS) were detected in hypothalamus, however, the roles of NO in hypothalamus was not fully studied. So, we tested the effects of NO on body temperature because preoptic-anterior hypothalamus was known as the presumptive primary fever-producing site. NO donor sodium nitroprusside (SNP, 4 nmol, i.c.v.) elicited marked febrile response, and this febrile response was completely blocked by indomethacin (a cyclooxygenase inhibitor). But, ODQ (selective guanylate cyclase inhibitor, $50\;{\mu}g,$ i.c.v.) did not inhibit fever induced by SNP. The cyclic GMP analogue dibutyryl-cGMP $(100\;{\mu}g,\;i.c.v.)$ induced significant pyreses, which is blocked by indomethacin. $N^G-nitro-L-arginine$ methyl ester (L-NAME, non selective NOS inhibitor) inhibited fever induced by $interleukin-1{\beta}\;(IL-1{\bata},\;10\;ng,\;i.c.v.),$ one of endogenous pyrogens. These results indicate that NO may have an important role, not related to stimulation of soluble guanylate cyclase, in the signal pathway of thermoregulation in hypothalamus.

• Nuclear Engineering and Technology
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• v.54 no.1
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• pp.386-400
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• 2022

Seismic fragility analysis, a part of seismic probabilistic risk assessment (SPRA), is commonly used to establish the relationship between a representative property of earthquakes and the failure probability of a structure, component, or system. Current guidelines on the SPRA of nuclear power plants (NPPs) used worldwide mainly reflect the earthquake characteristics of the western United States. However, different earthquake characteristics may have a significant impact on the seismic fragility of a structure. Given the concern, this study aimed to investigate the effects of earthquake characteristics on the seismic fragility of concrete containments housing the OPR-1000 reactor. Earthquake time histories were created from 30 ground motions (including those of the 2016 Gyeongju earthquake) by spectral matching to the site-specific response spectrum of Hanbit nuclear power plants in South Korea. Fragility curves of the containment structure were determined under the linear response history analysis using a lumped-mass stick model and 30 ground motions, and were compared in terms of earthquake characteristics. The results showed that the median capacity and high confidence of low probability of failure (HCLPF) tended to highly depend on the sustained maximum acceleration (SMA), and increase when using the time histories which have lower SMA compared with the others.

• Structural Engineering and Mechanics
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• v.82 no.3
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• pp.325-341
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• 2022

Previous major earthquakes indicated that the earthquake induced ground motions are typical non-stationary processes, which are non-stationary in both amplification and frequency. For the convenience of aseismic design and analysis, it usually assumes that the ground motions at structural supports are stationary processes. The development of time-frequency analysis technique makes it possible to evaluate the non-stationary responses of engineering structures subjected to non-stationary inputs, which is more general and realistic than the analysis method commonly used in engineering. In this paper, the wavelet-based stochastic vibration analysis methodology is adopted to calculate the non-stationary responses of multi-support structures. For comparison, the stationary response based on the standard random vibration method is also investigated. A frame structure and a two-span bridge are analyzed. The effects of non-stationary spatial ground motion and local site conditions are considered, and the influence of structural property on the structural responses are also considered. The analytical results demonstrate that the non-stationary spatial ground motions have significant influence on the response of multi-support structures.

• Journal of Periodontal and Implant Science
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• v.33 no.4
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• pp.651-671
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• 2003

The influence of calcium phosphate (Ca-P) coating on the bone response of titanium implants was investigated two types of titanium implants, i.e. as -machined ,as -machined with Ca-P coating, were prepared. The Ca-P coating produced by OCT Inc technique. These implants were inserted into the left and right femur of beagle dog, After implantation periods of 3 days, 1weeks, weeks, 4weeks, 8weeks, 12weeks. 24weeks, the bone-implant interface was evaluated histologically, histomorphometrically , and removal torque. Histological evaluation revealed no new bone formation around different implant materials after 2weeks of implantation. After 4 weeks, Ca-P coated implants showed a higher amount of bone contact than either of the non coated implants. After 12weeks, bone healing was almost completed. And implant were removed by reverse torque rotation with torque-measuring device. Mean torque values for 4weeks control were 2.375Kgf.cm and experimental were 2.725Kgf.cm. And mean torque values for 8weeks control were 1.25Kgf.cm and experimental were 1.0Kgf.cm On the basis of these findings, we concluded that deposition of a Ca-P coating on an implant has a beneficial effect on the bone response to this implant during the healing phase. Besides implant surface conditions the bone response is also determined by local implant site condition.