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Problems Associated with the Management of Nutrition Support Team in Hospitals in Korea (우리나라 병원에서의 영양지원팀 운영과 관련된 문제점에 관한 연구: 한 대학병원의 경우)

  • Kang, Hye-Jin;Shanmugam, Srinivasan;Yong, Chul-Soon;Kim, Jung-Ae;Rhee, Jong-Dal;Yoo, Bong-Kyu
    • Korean Journal of Clinical Pharmacy
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    • v.18 no.1
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    • pp.45-49
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    • 2008
  • The goal of this research was to identify problems associated with the management of nutrition support team (NST) in hospitals in Korea. Management status of NST in the hospitals was surveyed over the phone or interviewed by visit during August 2007. NST in foreign countries was collected by reference search and websites in the internet. Survey analysis also was performed during March, 2007 with forty-one medical staff in a university hospital located in Jinju, Kyungsangnamdo. Korean Society for Parenteral and Enteral Nutrition (KSPEN) was organized in 2001 and currently has thirty-three member hospitals with on-site NST as of August, 2007. Most of the member hospitals were big hospitals with more than 500 beds and were organized within five years. The most significant problem identified was the shortage of nutrition specialists exclusively involved in the NST. Survey analysis revealed that more than half of medical staff prescribed parenteral nutrition based on their own nutrition requirement calculation rather than consultation with NST. It appears that status of NST management of hospitals in Korea are considered to be at beginner stage and therefore, needs more aggressive advertising activity to increase consultation usage by medical staff.

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The Level of Serum Cholesterol is Negatively Associated with Lean Body Mass in Korean non-Diabetic Cancer Patients

  • Han, Ji Eun;Lee, Jun Yeup;Bu, So Young
    • Clinical Nutrition Research
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    • v.5 no.2
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    • pp.126-136
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    • 2016
  • Due to poor nutrition and abnormal energy metabolism, cancer patients typically experience the loss of muscle mass. Although the diabetic conditions or dyslipidemia have been reported as a causal link of cancer but the consequence of such conditions in relation to gain or loss of skeletal muscle mass in cancer patients has not been well documented. The purpose of this study was to investigate the relationship of lean body mass and systemic parameters related to lipid metabolism in non-diabetic cancer patients using data from the Korean National Health and Nutrition Examination Survey (KNHANES) 2008-2011. As results the level of serum total cholesterol (total-C) was negatively associated with both total lean body mass and appendicular lean body mass in cancer patients after adjustment for sex, physical activity, energy intake and comorbidity. The associations between consumption of dietary factors (energy, carbohydrate, protein and fat) and lean body mass were disappeared after adjusting comorbidities of cancer patients. Multivariate-adjusted linear regression analysis by quartiles of serum total-C showed that higher quartile group of total-C had significantly lower percent of lean body mass than reference group in cancer patients. The data indicate that serum lipid status can be the potential estimate of loss of skeletal muscle mass in cancer patients and be referenced in nutrition care of cancer patients under the onset of cachexia or parenteral/enteral nutrition. This data need to be confirmed with large pool of subjects and should be specified by stage of cancer or the site of cancer in future studies.

Chemical Behaviors of Elements and Mineral Compositions in Fault Rocks from Yangbuk-myeon, Gyeongju City, Korea (경주시 양북면 단층암의 원소거동과 광물조성 특성)

  • Song, Su Jeong;Choo, Chang Oh;Chang, Chun-Joong;Jang, Yun Deuk
    • The Journal of the Petrological Society of Korea
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    • v.22 no.2
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    • pp.137-151
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    • 2013
  • This study is focused on element behaviors and mineral compositions of the fault rock developed in Yongdang-ri, Yangbuk-myeon, Gyeongju City, Korea, using XRF, ICP, XRD, and EPMA/BSE in order to better understand the chemical variations in fault rocks during the fault activity, with emphasis on dependence of chemical mobility on mineralogy across the fault zone. As one of the main components of the fault rocks, $SiO_2$ shows the highest content which ranges from 61.6 to 71.0%, and $Al_2O_3$ is also high as having the 10.8~15.8% range. Alkali elements such as $Na_2O$ and $K_2O$ are in the range of 0.22~4.63% and 2.02~4.89%, respectively, and $Fe_2O_3$ is 3.80~12.5%, indicating that there are significant variations within the fault rock. Based on the chemical characteristics in the fault rocks, it is evident that the fault gouge zone is depleted in $Na_2O$, $Al_2O_3$, $K_2O$, $SiO_2$, CaO, Ba and Sr, whereas enriched in $Fe_2O_3$, MgO, MnO, Zr, Hf and Rb relative to the fault breccia zone. Such chemical behaviors are closely related to the difference in the mineral compositions between breccia and gouge zones because the breccia zone consists of the rock-forming minerals including quartz and feldspar, whereas the gouge zone consists of abundant clay minerals such as illite and chlorite. The alteration of the primary minerals leading to the formation of the clay minerals in the fault zone was affected by the hydrothermal fluids involved in fault activity. Taking into account the fact that major, trace and rare earth elements were leached out from the precursor minerals, it is assumed that the element mobility was high during the first stage of the fault activity because the fracture zone is interpreted to have acted as a path of hydrothermal fluids. Moving toward the later stage of fault activity, the center of the fracture zone was transformed into the gouge zone during which the permeability in the fault zone gradually decreased with the formation of clay minerals. Consequently, elements were effectively constrained in the gouge zone mostly filled with authigenic minerals including clay minerals, characterized by the low element mobility.

Exclusion of Na+ and ClIons by the central parenchyma in leaf sheaths of rice and the involvement of lamina joint

  • Neang, Sarin;Kano-Nakata, Mana;Yamauchi, Akira;Itani, Tomio;Maekawa, Masahiko;Mitsuya, Shiro
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.237-237
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    • 2017
  • Rice is highly sensitive to salt stress especially in its early growth stage, which thus is one of the major constraints in rice production. In rice plants, salt sensitivity is associated with the accumulation of $Na^+$ in the shoots, especially in the photosynthetic tissues. High salt concentrations in soil cause high $Na^+$ and $Cl^-$ transport to the shoot and preferential accumulation of those ions in older leaves, which decreases $K^+$ in the shoot, photosynthetic activity and grain yield. Salt exclusion capacity at the leaf sheath is therefore considered to be one of the main mechanisms of salt tolerance. In addition, it is suspected that the lamina joint might be involved in the salt transport from leaf sheath to leaf blade. This research aims to determine if leaf sheaths of rice exclude a large amount of $Na^+$ only or other ions such as $K^+$, $Ca^{2+}$, $Mg^{2+}$, and $Cl^-$ as well, to identify tissues in the leaf sheath, which accumulate $Na^+$, and to examine if the lamina joint is involved in the salt exclusion by the leaf sheath. The rice seedlings of salt tolerant genotype FL478 and salt sensitive genotype IR29 were independently treated with NaCl, KCl, $MgCl_2$ and $CaCl_2$, and Taichung 65 and its near-isogenic liguleless line (T65lg) were treated with NaCl. Then, the content of $Na^+$, $K^+$, $Ca^{2+}$, $Mg^{2+}$, and $Cl^-$ ions and their specific location were determined using Atomic Absorption Spectrometer, Ion Chromatograph, and Energy Dispersive X-ray Spectroscopy. Results showed that leaf sheaths of FL478 and IR29 accumulated a large amount of $Na^+$, $K^+$, $Ca^{2+}$, $Mg^{2+}$, and $Cl^-$ ons, and thus excluded them from leaf blades when treated with high concentration of each salt. When treated with NaCl, the highest $Na^+$ concentration was found in the basal part of leaf sheaths of both cultivars. Moreover, energy-dispersive X-ray spectroscopy revealed that the central parenchyma cells of the leaf sheath were the site where most Na, Cl, and K were retained under salinity in the salt tolerant genotype FL478. Also, the concentration of $Na^+$, $K^+$ and $Cl^-$ ions in leaf sheaths and leaf blades was comparable between T65 and T65lg, indicating that the lamina joint may not be involved in the exclusion of $Na^+$, $Cl^-$ and $K^+$ by the leaf sheath from the leaf blade under salinity. Therefore, we conclude that the central parenchyma cells of basal part of leaf sheath are the site that plays a physiological role to exclude $Na^+$ in the shoots of rice without the involvement of the lamina joint.

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A Study on the Design of Non-working Days Process by Analyzing Business Information (업무정보 분석을 통한 작업불능일 산정 프로세스 설계에 관한 연구)

  • Kim, Beop-su;Bang, Hong-soon;Choi, Byung-Ju;Kim, Ok-kyue
    • Korean Journal of Construction Engineering and Management
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    • v.19 no.5
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    • pp.61-69
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    • 2018
  • Construction projects consist of long-term on-site production, and most disciplines are featured by outdoor works. Therefore, when a process plan is established, non-working days are calculated and reflected in a process schedule to comply with the planned construction period. However, necessary information and working methods are different in the course of the work, so the method of calculation varies depending on persons even for the same site, and the result is also very different. Therefore, scientific and quantitative understanding of business information is needed. This study reconstructed non-working day estimation process by collecting and organizing the information necessary for non-working day estimation, and designed the demonstration screen based on the reconstructed process and verified through expert interview at each stage. As a result, it showed about 69% reduction of work time and reliability of 92% work information matrix, and 80% of the experts evaluated the systemization of the relevant work. This study is expected to improve the understanding of work and increase the efficiency of work performance, and the study on systemization in the future should be continued.

Characteristics of Marine Terrace Sediments Formed during the Marine Isotope Stage 5e in the West South Coast of the Korean Peninsula (한반도 서남해안 MIS 5e 해안단구의 퇴적층 특성 연구)

  • Yang, Dong-Yoon;Han, Min;Kim, Jin Cheul;Lim, Jaesoo;Yi, Sangheon;Kim, Ju-Yong
    • Economic and Environmental Geology
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    • v.49 no.6
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    • pp.417-432
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    • 2016
  • It was firstly revealed in this research that the marine terrace of the Ijin-ri (Bukpyung-myeon, Haenam-gun) was formed during the last interglacial (Marine Isotope Stage 5e; MIS 5e). The marine terrace totally ranging from 4.8 m (asl) to 8.8 m (asl) is subdivided into 4 units; Unit I ranges 4.8-5.3 m, unit II ranges 5.3-6.9 m, unit III ranges 6.9-8.3 m, and unit IV ranges 8.3-8.8 m. Strong evidences that units II and III were formed during MIS5e were obtained based on OSL dating, the physical characterizations such as particle size distribution, magnetic susceptibility and water content, principal element and trace element analyses, and quantitative clay mineral analysis for samples at the 30 cm intervals. The rounded gravels on the marine terrace are regarded to be originated from the clastic materials transported directly from the surrounding mountains toward the marine and abraded in the coastal area, without any fluvial processes. During the warmest period (125k, unit II), the increase in rainfall, along with the rapid rise in sea level, was likely caused the high amount of clastic materials transported to the upper part of the beach. As a result of comparing clay mineral ratios of study site with those derived from sediments of either tidal flats, or the Yellow Sea, it is interpreted that the sediments of study site were influenced from the marine. The results will be used to investigate the hydrological activity and sedimentary environment during the high sea level in the past.

Diversity of Uncultured Microorganisms Associated with the Anaerobic Pentachlorophenol Degradation Estimated by Comparative RELP Analysis of PCR-Amplified 16S rDNA Clones (16S rDNA 클론들의 RFLP 비교분석에서 얻어진 Pentachlorophenol의 혐기성 분해에 따른 미생물군집의 변화)

  • 성창수;권오섭;박영식
    • Korean Journal of Microbiology
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    • v.33 no.2
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    • pp.149-156
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    • 1997
  • We have employed comparative RFL,P(Restriction Fragment Ixngth Pol~iniorphism) analysis and molecular phylogenetic techniques to investigate the diversity of uncultured microorganisms associated with the anaerobic PCP degradation in PCP-adapted enrichment cultures inoculated by samples from anaerobic cewage sludgc(Jangrim, Pusan) and leachate of landfill site(Kimhae). 16s rDNA cloncs were obtairted by PCR amplification of mixed population DNAs extracted directly from the nonactive and active stage ol each PCP-adapted culture. After three rounds of comparative RFLP analyses. two RFLP types. designated as Ala and Hld, were found prevalent and common in both active stage samples. Thc analysis of phylogenctic diversity bawd on the 5'-terminal 180 nt of sequences from whole clones of the Ala and Bld RFLP types showed close similarity among themselves. In case of Bld clones, 7XQ of them shared identical sequences. Thcse resuliq suggest that the clones of both RFLP types wcre originated from highly affiliated microorganisms which are e~iriched as a result of metabolic activity to PCP. The full-length 16s rRNA sequence of each representative clone from both RFLP types was determined. and an Ala clone w i n found to he related to Clo.strrdiurn ulfutzac~(Genk~ank No. Z69203) and a Bld clone to Thermobacteroides proteolyticus(Genbank No. X09335), with sequence similarities of 89%' and 97%. respectively.

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HISTOLOGICAL TISSUE RESPONSES OF DEMINERALIZED ALLOGENEIC BONE BLOCK GRAFT IN RABBITS (가토 탈회 동종골편 이식시 조직반응에 관한 연구)

  • Jun, Young-Hwan;Kim, Young-Jo;Min, Seung-Ki;Um, In-Woong;Lee, Dong-Keun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.15 no.1
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    • pp.63-79
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    • 1993
  • To repair bony defects with tansplanted bone in the body, fresh autogenous bone is undoubtly, the most effective bone graft for clinical applications. But the demineralized bone has the matrix-induced bone formation which was suggested by Urist in 1965. Many authors assisted that demineralized bone powder induces phenotypic conversion of mesenchymal cells into osteoblasts, with high-density bone formation. The process of inducing differentiated cells becomes osteogenic properties. The purpose of this study was to evaluate the osteoinductive capacity of allogenic freeze-dried demineralized bone block (FDD, $7{\times}7mm$) and to compare FDD with the same sue of deep-frozen allogenic bone(DF), fresh autogenous bone (A) after implantation. The histological and ultrastructural features of tissue responses were examined after 1, 2, 4, 6, 8 weeks implantation of each experimental groups in the operative site of the New Zealand white rabbits. The results were as follows : 1. Inflammatory cell infiltration generally has appeared at 1 week, but reduced at 4 weeks in each group, but most severe in DF group. 2. Osteoblastic activity has increased for 4 weeks, but decreased at 6 weeks in each group and there was no significant difference among experimental groups. 3. New bone formation has begun at 1week, least activations in A groups, and showed the revesal line of bone formation among each group at 6 to 8 weeks. 4. Bone resorption has appeared at 1 week, but disappeared at 4 weeks in both A and DF groups, but more severe in DF than A groups. 5. In ultrastructural changs, the DF group have showed the most remarkable osteoclastic activities among experimental groups. 6. Osteoid or tangled collagen fibrils near the implanted sites were replaced by more mature, lamellated bony trabeculae during bone remodeling. There was little difference among each experimental groups. 7. During the convertion osteoblasts to osteocytes which embedded within the bone matrix, there was organ-less-poor cytoplasm, increased nuclear chromatin, abundant rough endothelial reticulum (RER) in each groups. From the above the findings, the DF group shored more bone resorption and foreign body reaction than FDD and A groups, and FDD group showed more new bone formation or osteoblastic activity than DF and A groups in early stage. There was no significant difference of cellular activities among the FDD DF, and A groups according to the time.

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Geochemical Characteristics and Quaternary Environmental Change of Unconsolidated Sediments from the Seokgwan-dong Paleolithic Site in Seoul, Korea (서울 석관동 유적의 미고결 퇴적층의 지구화학적 특성 및 제4기 지표환경변화)

  • Lee, Hyo-Min;Lee, Jin-Young;Kim, Ju-Yong;Hong, Sei-Sun;Park, Jun-Bum
    • The Journal of the Petrological Society of Korea
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    • v.25 no.4
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    • pp.373-388
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    • 2016
  • To understand human activity in the past, the information about past environmental change including geomorphological and climatic conditions is essential and this can be traced by using age dating and geochemical analysis of sediments from the prehistoric sites. The sedimentary sequence of Seokgwan-dong Paleolithic Site located in Seoul was 5m long unconsolidated sediments and consists of lower part bedrock weathering sediments, slope deposits and upper-part fluvial deposits. In this study, upper part sediments were used to reconstruct past environmental change through age dating and various physical and chemical analyses including grain size, magnetic susceptibility and mineral and elements. The fluvial sediments can be divided into 4 units including three organic layers. Grain size analysis results showed that the sediments were very poorly sorted with fining upward features. Magnetic susceptibility was relatively high in the organic layers, indicating environmental changes causing mineral composition change at that times. The mineral and major element composition are similar to Jurassic biotite granite which mainly consists of quartz, K-feldspar, biotite and muscovite. The radiocarbon age of $14,240{\pm}80yr$ BP was obtained from the lower most organic layer of Unit III(O), suggesting that the fluvial sediments formed at least from the early stage of deglacial period after the end of Last Glacial Maximum. Subsequent wet and warm climates and resultant fluvial process including slope sedimentation during the Holocene may have been responsible for the sedimentary sequence in Seokgwan-dong paleolithic site and surrounding area. The observed organic layers suggests frequent wetland occurrence combined with natural levee changes in this area.

Isolation and Characterization of Eukaryotic Translation Initiation Factor 5A (eIF-5A) from Potato (감자로부터 Eukaryotic Translation Initiation Factor 5A (elF-5A) 유전자의 동정 및 발현 분석)

  • 인준교;신동호;최관삼;양덕춘
    • Korean Journal of Plant Tissue Culture
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    • v.28 no.5
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    • pp.283-287
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    • 2001
  • Differential display based on PCR was employed to identify genes expressed during tuber-developing stage of potato (Solanum tuberosum L. cv. Irish Cobbler). An eukaryotic initiation factor 5A (eIF-5A) clone isolated from a cDNA library constructed with developing micro-tuber using a probe of PCR fragment. We isolated three positive clones and ore of them contained open reading frame. This clone revealed high sequence similarity to tomato eIF 5A cDNA. At the DNA level, there is 94.8% identity with the tomato eIF-5A4, whereas at the protein level there is a high identity with 97.5%. The potato eIF 5A clone is 716 bp in length and contains a single open reading frame from 57 to 539 bp, a 56 bp 5'-untranslated region and a 177 bp 3'-untranslated region. The deduced protein composed of 160 amino acid residues, with a predicted molecular mass of 17.4 kD and an estimated pl of 5.5. The sequence of 12 (STSKTGKHGHAK) amino acids among eIF-5A proteins is perfectly conserved from yeast to human. That sequence in potato eIF-5A protein is also conserved at position 46 to 57 amino acid. This region embeds the post-translational modification site of the lysine residue (at the seventh K) to hypusine that is crucial to eIF-5A activity. The northern blot analysis of eIF5A has shown abundant expression, mainly in flower organs (stamen, ovary, petal, sepal), fruit and stolen.

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