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A Case of Molluscum Contagiosum (전염성 연속성 치험 1례)

  • Hur, Inn-Hee;Hong, Sung-Min;Sim, Sung-Yong;Kim, Kyung-Jun;Byun, Hak-Sung
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.20 no.1 s.32
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    • pp.250-255
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    • 2007
  • Molluscum contagiosum(MC) is a viral disorder of the skin and mucous membranes characterized by decrete single or multiple, flesh-colored papules. There was the 6 years old woman who suffered from umbilicated papules and pruritis of back. First, Her mother choiced western medicine, and was treatded with topical(ointment applicatoin) and surgical(curettage) method. Despite of western medical treatment during 3 months, there was not recovery of symptoms. So, she visited the Dept. of Opthalmology & Otorhinolaryngology & Dermatology, College of Oriental Medicine, Kyungwon University for oriental medical treatment. The oriental medical treatment reduced the symptoms of the patient remarkably during 8weeks. So we report the healing process and result of this patient in this study. There is few report that treat MC with oriental medical method. If more clinical trials like this are proved to be effective, we can expect that oriental medical treatment will be a good method in MC.

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Effects of Individualized Intensive Physical Therapy for a Child with MECP2 Duplication Syndrome: A Case Study

  • Chang-Ho Kim
    • Journal of the Korean Society of Physical Medicine
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    • v.18 no.4
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    • pp.29-35
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    • 2023
  • PURPOSE: High-intensity physical therapy may help improve some gross motor developmental delays through an increased treatment frequency. This study describes an increase in physical therapy frequency and intensity over an eight-week time frame for a child with a rare genetic neurodevelopmental disorder. METHODS: A single-subject research was performed. The subject was a nine-year-old boy with MECP2 Duplication Syndrome. The outcome measure consisted of one time before and after the intervention. An intensive physical therapy program was applied to this subject. The treatments included reciprocal crawling, high kneeling, tailor sitting, weight-bearing and shifting training to facilitate ankle balance strategies and training to walk without assistance. RESULTS: After the eight-week follow-up, the child achieved a gradual improvement in the gross motor function measures, and the mother reported that the child frequently engaged in tailor sitting and independently walking. CONCLUSION: This case study highlights that intensive physical therapy improved the overall motor function of a child with MECP2 duplication syndrome.

Exome sequencing in a breast cancer family without BRCA mutation

  • Noh, Jae Myoung;Kim, Jihun;Cho, Dae Yeon;Choi, Doo Ho;Park, Won;Huh, Seung Jae
    • Radiation Oncology Journal
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    • v.33 no.2
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    • pp.149-154
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    • 2015
  • Purpose: We performed exome sequencing in a breast cancer family without BRCA mutations. Materials and Methods: A family that three sisters have a history of breast cancer was selected for analysis. There were no family members with breast cancer in the previous generation. Genetic testing for BRCA mutation was negative, even by the multiplex ligation-dependent probe amplification method. Two sisters with breast cancer were selected as affected members, while the mother of the sisters was a non-affected member. Whole exome sequencing was performed on the HiSeq 2000 platform with paired-end reads of 101 bp in the three members. Results: We identified 19,436, 19,468, and 19,345 single-nucleotide polymorphisms (SNPs) in the coding regions. Among them, 8,759, 8,789, and 8,772 were non-synonymous SNPs, respectively. After filtering out 12,843 synonymous variations and 12,105 known variations with indels found in the dbSNP135 or 1000 Genomes Project database, we selected 73 variations in the samples from the affected sisters that did not occur in the sample from the unaffected mother. Using the Sorting Intolerant From Tolerant (SIFT), PolyPhen-2, and MutationTaster algorithms to predict amino acid substitutions, the XCR1, DLL1, TH, ACCS, SPPL3, CCNF, and SRL genes were risky among all three algorithms, while definite candidate genes could not be conclusively determined. Conclusion: Using exome sequencing, we found 7 variants for a breast cancer family without BRCA mutations. Genetic evidence of disease association should be confirmed by future studies.

Effects of Abscisic Acid on the Epidermal Structure and Ontogeny of Stomata in Orostachys malacophyllus Leaves (둥근바위솔(Orostachys malacophyllus) 잎의 표피구조와 기공발생에 미치는 Abscisic Acid의 영향)

  • 김진성
    • Journal of Plant Biology
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    • v.30 no.1
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    • pp.21-30
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    • 1987
  • The effects of abscisic acid(ABA) spraying for 12 weeks on the stomatal types and frequencies of O. malacophyllus leaves were summarized as follows. ABA inhibited the growth of O. malacophyllus. The prominent effect of ABA on the epidermal structure was the promotion of senescence such as thickness of cell walls, smooth sinuosity of cell walls, and large size of epidermal cells. The stomatal frequency was decreased to 23% by 10$\mu\textrm{g}$ ml-1 ABA and to 48% by 100$\mu\textrm{g}$ml-1, and also the stomatal size was more or less smaller than that of control. The developing secondary stomatal mother cell was not found in both 10 and 100$\mu\textrm{g}$ml-1ABA, but the arrested secondary stomatal mother cell was rarely found in 10$\mu\textrm{g}$ ml-1 ABA. The formation of normal stomatal types such as helico-eumesogenous and aniso-eumesogenous was found in both 10 and 100 $\mu\textrm{g}$ ml-1 ABA asin well as control. Also nine abnormal stomatal types were found, and the frequencies were promoted to 6% by 10 $\mu\textrm{g}$ ml-1 ABA and to 17% by 100 $\mu\textrm{g}$ ml-1 ABA. Among these abnomal stomata, four types such as aborted stomata, single-aborted guard cells, arrested stomata, and modified stomatal complexes were found in control as well as in 10 and 100 $\mu\textrm{g}$ ml-1 ABA, but five types such as wrenched stomata, unequal stomata, wavy guard cells, guard cells overlapped by guard cells, and dissolved cell wall stomata were found in both 10 and 100 $\mu\textrm{g}$ ml-1ABA. The modified stomata complexes were abnormal stomatal types which were newly found and also were varied in types.

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Women s View to Pregnancy (여성들의 임신관에 대한 현상학적 연구)

  • 조주연;이미라
    • Journal of Korean Academy of Nursing
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    • v.26 no.1
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    • pp.5-14
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    • 1996
  • The purpose of this study is to find the Korean women's view to pregnancy within the Korean cultural context, to help nurses understand psychosocioemotional schema of the pregnant women, and to contribute to theory-building on the meaning of pregnancy. The interviewees were 21 women in their twenties or thirties and they were selected by theoretical sampling technique. Thirteen women of the interviewees were single and others married. Data were collected by in-depth interviews from September November in 1994. Interviews were tape-recorded and transcribed. Data were analyzed by Van Kaam's phenomenological method. Results were as follows. Eighty two descriptive expression were found and they were grouped under fourteen common factors. These are 「to maintain family」, 「instinct」, 「obligation」, 「what one should do」, 「to make home」, 「to tie couple firmly」, 「means to overcome a period of lassitude」, 「token of love」, 「hope」, 「to avoid loneliness」, 「wanted to have a baby」, 「to provide for old ages」, 「to be a mother」, 「to achieve her desire through baby」. Finally, fourteen common factors were grouped under four higher categories. Five common factors, 「to maintain family」, 「instinct」, 「obligation」, 「what one should do」, 「to make home」 were grouped under〈custom〉. Three factors, 「to tie couple firmly」, 「means to overcome a period of lassitude」, 「token of love」 were grouped under 〈love between couple〉. Four factors, 「hope」, 「to avoid loneliness」, 「wanted to have a baby」, 「to provide for old ages」 were grouped under 〈pursuiting safety〉. Two factors, 「to be a mother」, 「to achieve her desire through baby」 were grouped under 〈self-fulfillment〉. At present, the most distinguishing motivation of childbearing was rooted in the cultural custom. Korean women thought that it was their duties to have children and children were necessary in life. But they were beginning to recognize that baby could tie couple more firmly and get rid of their loneliness. Korean women no longer considered their children as the one who would take care of them when they were old or who would satisfy their unmet needs. As pregnancy is not women's duty only, authors recommend further studies on men's view to pregnancy.

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Genetic polymorphism analysis of somatic embryo-derived plantlets of Cymbopogon flexuosus through RAPD assay

  • Bhattacharya, S.;Dey, T.;Bandopadhyay, T.K.;Ghosh, P.D.
    • Plant Biotechnology Reports
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    • v.2 no.4
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    • pp.245-252
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    • 2008
  • The genetic status of somatic embryo-derived plantlets of Cymbopogon flexuosus was examined by randomly amplified polymorphic DNA (RAPD) analysis. Auxins such as 2, 4-dichlorophenoxyacetic acid (2, 4-D) (1-4 mg/l) were used in Murashige and Skoog (MS) medium for induction of calli from rhizomatous explants of Cymbopogon flexuosus. Optimum calli were induced on MS medium supplemented with 2, 4-dichlorophenoxyacetic acid (2, 4-D) (3.5 mg/l) alone or in combination with $N^6-benzyladenine$ (2 mg/l). Somatic embryogenesis was achieved from long term calli when cultured on MS medium containing 2, 4-dichlorophenoxyacetic acid (2, 4-D) (2 mg/l) along with $N^6-benzyladenine$ (BA) (1-2 mg/l). Regeneration was achieved when freshly induced embryogenic calli were sub-cultured on MS medium supplemented with $N^6-benzyladenine$ (3 mg/l) alone. Long-term cultured embryos showed profuse minute rooting on regeneration medium supplemented with N6 -benzyladenine (3 mg/l). Microshoots were rooted in the presence of indole-butyric acid (IBA) (2 mg/l). DNA samples from the mother plant and 18 randomly selected regenerated plants from a single callus were subjected to RAPD analysis with 6 arbitrary decamer primers for the selection of putative somaclones. A total of 64 band positions were scored, out of which 19 RAPD bands were polymorphic. From genetic similarity coefficient based on RAPD band data sharing, it was found that the majority of the clones were almost identical or more than 92% similar to the mother plant, except CL2 and CL9 (66%) which showed highest degree of genetic change with CL2 and CL9 showing presence of two non-parental bands each.

Perception and Use of Weaning Diets by Housewives in Gwangju-Jeonnam Regions (광주${\cdot}$전남지역 주부들의 이유식에 대한 인식 및 이용 실태)

  • Park, Young-Hee;Lee, Sung-Sug;Jung, Lan-Hee
    • Korean journal of food and cookery science
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    • v.22 no.6 s.96
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    • pp.799-807
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    • 2006
  • This study was designed to assess the perception and use of weaning diets and to serve as a guideline of processed weaning diets through a survey focused on the Gwangju-Jeonnam regions. The following results were obtained. Most subjects mixed 'home-made' and 'commercial' weaning diets and considered weaning diets as 'a diet for supplementing insufficient nutrition'. The most frequently used type of weaning diet was 'a kind of gruel with vegetables or meat', followed by 'boiling powder with water' and 'grinding or crushing fruits'. Two thirds (68%) of subjects had experienced buying weaning diets, mainly a powder type. The most common reason to buy weaning diets was 'troublesome', followed by 'excellent nutrition', 'convenient to go out', and 'don't know how to make'. The following results according to factors were found. The types of provided and of weaning diets were significantly different by age; the understanding of weaning diets, by education and mothers' employment; and where to get information about weaning diets, by economic status. The highest request for developing weaning diets was a type of 'powder' and 'gruel', and the highest cooking type was 'adding boiling water', followed by 'a semi-cooking product' and 'a finished product'. 'Retort pouch' package, a 'single' package unit, and 'keeping cold' were also requested by the participants. A desirable package unit in developing weaning diets was significantly different by mother's employment; the cooking type of product, by economic status; a way to keep product, by mother's employment; and package types, by education and economic status. When weaning diets were made by environmentally friendly agriculture, 69.5% of subjects were willing to purchase them. With the increase in economic status, education, and employment rate, the use of weaning diets on the market will increase. For this reason, correct nutrition education is needed. With the increasing demand for environmentally friendly agriculture, a variety of weaning diets should be developed to meet this demand.

The aspects of women's play and Eomeoni(Mother) of Geugyesuryeonguho(극예술연구회) (극예술연구회 <어머니>와 여성 연극의 양상)

  • Kim, Nam-seok
    • (The) Research of the performance art and culture
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    • no.41
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    • pp.39-67
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    • 2020
  • So far, research on the 10th performance of the Geukye Suryeonguhoe has been rarely conducted. In particular, Lee Seo-hyang's Eomeoni was rarely studied, and it was only recorded that at most it was one of the 10th performances. Although the script of Eomeoni remains, and the 10th performance was an important regular performance, it should be said that the status of this research is very poor. It seems to be the result of failing to accurately examine the historical value and meaning of the single act drama Eomeoni. In order to solve these problems, it is necessary to look at the performance situation of Eomeoni and to investigate the situation at the time of Geugyesuryeonguhoe. In addition, the reason for selecting Eomeoni, the stage performance situation, theatrical elements, stage design, and related evaluations should be analyzed throughout. This study focused on examining the status of Eomeoni's performance and examining its significance, and intends to examine the flow of feminist play as a context of the Geeugyesuryeonguhoe through the conclusion.

Fruiting Body Formation of Cordyceps militaris from Multi-Ascospore Isolates and Their Single Ascospore Progeny Strains

  • Shrestha, Bhushan;Han, Sang-Kuk;Sung, Jae-Mo;Sung, Gi-Ho
    • Mycobiology
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    • v.40 no.2
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    • pp.100-106
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    • 2012
  • Interest in commercial cultivation and product development of Cordyceps species has shown a recent increase. Due to its biochemical and pharmacological effects, Cordyceps militaris, commonly known as orange caterpillar fungus, is being investigated with great interest. Cultivation of C. militaris has been practiced on a large scale in order to fulfill a demand for scientific investigation and product development. Isolates of C. militaris can be easily established from both spores and tissue. For isolation of spores, ascospores released from mature stromata are trapped in sterile medium. Multi-ascospore isolates, as well as combinations of single ascospore strains, are used for production of fruiting bodies. Progeny ascospore strains can be isolated from artificial fruiting bodies, thus, the cycle of fruiting body production can be continued for a long period of time. In this study, we examined fruiting body production from multi-ascospore isolates and their progeny strains for three generations. $F_1$ progeny strains generally produced a larger number of fruiting bodies, compared with their mother multi-ascospore isolates; however, $F_2$ and $F_3$ progeny strains produced fewer fruiting bodies. Optimum preservation conditions could help to increase the vitality of the progeny strains. In order to retain the fruiting ability of the strains, further testing of various methods of preservation and different methods for isolation should be performed.

Analysis of Newspaper Articles on Child Abuse Deaths (아동학대 사망사건에 대한 신문기사 분석)

  • Kim, Jihae;Chung, Ickjoong;Lee, Heeyoun;Kim, Kyunghee
    • Korean Journal of Social Welfare
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    • v.65 no.2
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    • pp.131-154
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    • 2013
  • Although fatalities due to child abuse are frequently happened, there has been a dearth of research on the topic. The present research analyzes deaths due to child abuse in representative newspapers in order to examine incidences, causes, and characteristics of child abuse. The results showed that from 2000 to 2012 child abuse deaths occurred 141 cases. Most deaths due to child abuse were committed by single mothers, biological mothers, cohabiting women and stepmothers, and biological fathers. As regards the reasons of deaths due to child abuse, the frequency of newborn infant deaths as the result of abuse by single mother or single parent was the highest, and lack of parenting skills, postpartum depression, hardships of living and lack of financial abilities were followed. Also, subjects received extensive media coverage were crime compositions-stereotypes of child abusers, habitual and continual child abuse, lack of child abuse reporting and prevention system, and mild penalties. Finally, based on the results of the study, the implications to prevent and resolve deaths due to child abuse were discussed.

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