• Title/Summary/Keyword: simultaneous diagnosis

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Development of 64 Channel Cardiac Mapping System Using Microcomputer (마이크로컴퓨터를 이용한 64채널 심장전기도시스템개발)

  • 정성헌;김원기
    • Journal of Biomedical Engineering Research
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    • v.12 no.4
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    • pp.303-308
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    • 1991
  • Computer assisted cardiac mapping system has made it possible to display local activation times of the heart using a simultaneous multi-point data aquisition system, and opened an era in electrophyslology guided cardiac arrhythmia surgery especially in ventricular tachycardia. In this study, we have developed a 64 channel computerized cardiacmapping system us:ng a micro-computer for basic reasearch of electrophysiology and electrical propagation in cardiac arrhythmias. The significant tasks of this study were the simultaneous acquisition of large amount of data from 64 sites, accurate and rapid analysis, and the effective display of the analyzed data. To solve these problems, we made a 64 channel signal pre-processing board in order to amplify and fitter the raw signals. And we developed the soflu'are Yor cardiac isochronous mapping whictl is presented immediately ama computer-generated graphics. This system is expected 4o enable us to study pathophyslology of cardiac arrhythmia and to improve the results of diagnosis and surgical treatments for cardiac arrhythmia.

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Spontaneous Spinal Subdural Hematoma with Simultaneous Cranial Subarachnoid Hemorrhage

  • Jung, Hwan-Su;Jeon, Ikchan;Kim, Sang Woo
    • Journal of Korean Neurosurgical Society
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    • v.57 no.5
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    • pp.371-375
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    • 2015
  • Spontaneous spinal subdural hematoma is reported at a rare level of incidence, and is frequently associated with underlying coagulopathy or those receiving anticoagulant or antiplatelet agents; some cases accompany concomitant intracranial hemorrhage. The spontaneous development of spinal subdural hemorrhage (SDH) is a neurological emergency; therefore, early diagnosis, the discontinuation of anticoagulant, and urgent surgical decompression are required to enable neurological recovery. In this report, we present a simultaneous spinal subdural hematoma and cranial subarachnoid hemorrhage, which mimicked an aneurysmal origin in a female patient who had been taking warfarin due to aortic valve replacement surgery.

Autonomous Navigation System of an Unmanned Aerial Vehicle for Structural Inspection (무인 구조물 검사를 위한 자율 비행 시스템)

  • Jung, Sungwook;Choi, Duckyu;Song, Seungwon;Myung, Hyun
    • The Journal of Korea Robotics Society
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    • v.16 no.3
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    • pp.216-222
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    • 2021
  • Recently, various robots are being used for the purpose of structural inspection or safety diagnosis, and their needs are also rising rapidly. Among the structural inspection using robots, a lot of researches has recently been conducted on inspection of various facilities and structures using an unmanned aerial vehicle (UAV). However, since GNSS (Global Navigation Satellite System) signals cannot be received in an environment near or below structures, the operation of UAVs has been done manually. For a stable autonomous flight without GNSS signals, additional technologies are required. This paper proposes the autonomous flight system for structural inspection consisting of simultaneous localization and mapping (SLAM), path planning, and controls. The experiments were conducted on an actual large bridge to verify the feasibility of the system, and especially the performance of the proposed SLAM algorithm was compared through comparative analysis with the state-of-the-art algorithms.

Steel Plate Faults Diagnosis with S-MTS (S-MTS를 이용한 강판의 표면 결함 진단)

  • Kim, Joon-Young;Cha, Jae-Min;Shin, Junguk;Yeom, Choongsub
    • Journal of Intelligence and Information Systems
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    • v.23 no.1
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    • pp.47-67
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    • 2017
  • Steel plate faults is one of important factors to affect the quality and price of the steel plates. So far many steelmakers generally have used visual inspection method that could be based on an inspector's intuition or experience. Specifically, the inspector checks the steel plate faults by looking the surface of the steel plates. However, the accuracy of this method is critically low that it can cause errors above 30% in judgment. Therefore, accurate steel plate faults diagnosis system has been continuously required in the industry. In order to meet the needs, this study proposed a new steel plate faults diagnosis system using Simultaneous MTS (S-MTS), which is an advanced Mahalanobis Taguchi System (MTS) algorithm, to classify various surface defects of the steel plates. MTS has generally been used to solve binary classification problems in various fields, but MTS was not used for multiclass classification due to its low accuracy. The reason is that only one mahalanobis space is established in the MTS. In contrast, S-MTS is suitable for multi-class classification. That is, S-MTS establishes individual mahalanobis space for each class. 'Simultaneous' implies comparing mahalanobis distances at the same time. The proposed steel plate faults diagnosis system was developed in four main stages. In the first stage, after various reference groups and related variables are defined, data of the steel plate faults is collected and used to establish the individual mahalanobis space per the reference groups and construct the full measurement scale. In the second stage, the mahalanobis distances of test groups is calculated based on the established mahalanobis spaces of the reference groups. Then, appropriateness of the spaces is verified by examining the separability of the mahalanobis diatances. In the third stage, orthogonal arrays and Signal-to-Noise (SN) ratio of dynamic type are applied for variable optimization. Also, Overall SN ratio gain is derived from the SN ratio and SN ratio gain. If the derived overall SN ratio gain is negative, it means that the variable should be removed. However, the variable with the positive gain may be considered as worth keeping. Finally, in the fourth stage, the measurement scale that is composed of selected useful variables is reconstructed. Next, an experimental test should be implemented to verify the ability of multi-class classification and thus the accuracy of the classification is acquired. If the accuracy is acceptable, this diagnosis system can be used for future applications. Also, this study compared the accuracy of the proposed steel plate faults diagnosis system with that of other popular classification algorithms including Decision Tree, Multi Perception Neural Network (MLPNN), Logistic Regression (LR), Support Vector Machine (SVM), Tree Bagger Random Forest, Grid Search (GS), Genetic Algorithm (GA) and Particle Swarm Optimization (PSO). The steel plates faults dataset used in the study is taken from the University of California at Irvine (UCI) machine learning repository. As a result, the proposed steel plate faults diagnosis system based on S-MTS shows 90.79% of classification accuracy. The accuracy of the proposed diagnosis system is 6-27% higher than MLPNN, LR, GS, GA and PSO. Based on the fact that the accuracy of commercial systems is only about 75-80%, it means that the proposed system has enough classification performance to be applied in the industry. In addition, the proposed system can reduce the number of measurement sensors that are installed in the fields because of variable optimization process. These results show that the proposed system not only can have a good ability on the steel plate faults diagnosis but also reduce operation and maintenance cost. For our future work, it will be applied in the fields to validate actual effectiveness of the proposed system and plan to improve the accuracy based on the results.

MicroRNAs as Novel Biomarkers for the Diagnosis of Alzheimer's Disease and Modern Advancements in the Treatment

  • Gunasekaran, Tamil Iniyan;Ohn, Takbum
    • Biomedical Science Letters
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    • v.21 no.1
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    • pp.1-8
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    • 2015
  • Alzheimer's disease is a common form of dementia occurring among the elderly population and can be identified by symptoms such as cognition impairments, memory loss and neuronal dysfunction. Alzheimer's disease was found to be caused by the deposition of $\beta$-amyloid plaques and neurofibrillary tangles. In addition, mutation in the APP (Amyloid precursor protein), Presenilin 1 (PSEN1) and Presenilin 2 (PSEN2) genes were also found to contribute to Alzheimer's disease. Since the potential conformational diagnosis of Alzheimer's disease requires histopathological tests on brain through autopsy, potential early diagnosis still remains challenging. In recent years, several researches have proposed the use of biomarkers for early diagnosis. In cerebrospinal fluid (CSF), $\beta$-amyloid(1-42), phosphorylated-tau and total tau were suggested to be effective biomarkers for Alzheimer's disease diagnosis. However, a single biomarker might not be sufficient for potential diagnosis of Alzheimer's disease. Thus, the use of RNA interference (RNAi) through microRNAs (miRNAs) has been proposed by several researchers for simultaneous analysis of several biomarkers using microarray technology. These miRNA based biomarkers can be analysed from both blood and CSF, but miRNAs from blood are advantageous over CSF as they are non-invasive and simple for collection. Moreover, the RNAi based therapeutics by siRNA (short interference RNA) or shRNA (short hairpin RNA) have also been proposed to be effective in the treatment of Alzheimer's disease. This review describes the promising application of RNAi technology in therapeutics and as a biomarker for both Alzheimer's disease diagnosis and treatment.

THE DIAGNOSTIC EFFECT OF THE SIMULTANEOUS MULTIFILM INDIVIDUALIZED LATERAL TOMOGRAPHY IN THE DIAGNOSIS OF THE TEMPOROMANDIBULAR DISORDERS (악관절장애진단에 있어서 동시다층개별화측방단층촬영의 진단효과)

  • Lee Woo-Shik;Park Tae-Won
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.21 no.2
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    • pp.235-248
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    • 1991
  • This study was designed to evaluate the diagnostic effect of the simulatneous multifilm individualized lateral tomography in the diagnosis of the temporomandibular disorders. The subjects consisted of 29 patients with symptoms of the temporomandibular disorders. The panoramic view, oblique lateral transcranial radiograph (OLTC) (Hirozontal angulation 0°, Vertical angulation 29°), submentovertex view, and simultaneous multifilm individualized lateral tomographs (SMFI) in centric occlusion (2.5㎜ thickness difference, 5 layers) were taken for the patients. This study compared the findings from each radiographs in the determining of mandibular condylar position with dual linear measurement of the subjective closest posterior and subjective closest anterior interarticular space and in the determining of bony changes on the studied 30 temporomandibular joints (TMJ) with symptoms of the temporomandibular disorders. The results were as follows: 1. The distribution of condylar position of OLTC and 5 layers of SMFI depended on the radiographs (p<0.05). The condylar position and the distribution of condylar position of OLTC were more similar to lateral sections of the SMFI than mesial sections, and in the distribution of the condylar position of SMFI, the more lateral sections of SMFI, the more concentric 2. positions. There were 10 cases in which all layers showed the same condylar position as that of OLTC. There were 3 cases in which no layers showed the same condylar position as that of OLTC. 3. In the SMFI of 30 Temporomandibular joints studied, there is 13 cases in which all five layers represented the same condylar position in the same TMJ and 11 cases in which 4 layers represented the same condylar position in the same TMJ and 6 cases in which 3 layers represented the same condylar position in the same TMJ. So at least 3 layers of SMFI represented same condylar position in the same TMJ. 4. The bony changes were not detected in conventional radiographs on the temporomandibular joint and the bony changes were not detected in simultaneous multifilm individualized lateral tomographs. The bony changes were detected in conventional radiographs on the temporomandibular joint and the bony changes were detected in simultaneous multifilm individualized lateral tomographs. SMFI provided a meams for a three dimensional visualization of the shape, the position and the extent of bony changes of TMJ.

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THE EFFECT OF SIMULTANEOUS TREATMENT WITH ACUPUNCTURE, HERB MEDICATION AND NON-INVASIVE LASER IRRADIATION OF BLOOD VESSEL ON HEADACHE (침(鍼)과 한약(韓藥) 그리고 비침습 혈관 레이저를 이용한 두통(頭痛) 치료 효과)

  • Hwang Seon-Mi;Lee Seung-Jin;Chung Dae-Kyoo
    • Journal of Oriental Neuropsychiatry
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    • v.12 no.2
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    • pp.95-102
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    • 2001
  • 1. Purpose : The present study was carried out to evaluate the effects of simultaneous treatment with acupuncture, herb medication and non-invasive laser irradiation of blood vessel on the pain control of primary headache. 2. Methods : 30 outpatients who visited in the oriental medical hospital of Kyungsan University from April 10, 2001 to Oct. 10, 2001, based on symptoms and the results of pulse diagnosis, stress test(ABR-2000) and iridology test, were observed on the pain control of primary headache like tension or stress-induced headache. 1)Acupuncture and herbal medicine : Acupuncture treatment and herb medication widely used for headache were carried out simultaneously. 2)Non-invasive laser irradiation : Laser irradiation was undertaken on brachial vein with Lapex-2000 for 30minutes a day for 5 to 15days. 3. Result and Conclusion: In patients with headache, triglyceride mean values decreased from $168.57{\pm}26.90mg/dL$ to $154.23{\pm}28.66mg/dL$ and total cholesterol mean values decreased from $202.23{\pm}22.17mg/dL$ to $194.57{\pm}19.32mg/dL$, after simultaneous treatment with acupuncture, herb medication and non-invasive laser irradiation of blood vessel. And these results suggest that these simultaneous treatment has significant effects in tension and stress-induced headache.: Experiment subjects considered as shown the validity in the headache estimated 80%.

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Arteriovenous Fistula following Lumbar Laminectomy - A Case - (요추궁 절제술 후 발생한 동정맥루)

  • 오중환
    • Journal of Chest Surgery
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    • v.24 no.6
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    • pp.605-609
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    • 1991
  • The formation of postlaminectomy arteriovenous fistula is unusual and the rongeur during discectomy with resultant simultaneous damage to artery and vein is causative. The delay in diagnosis is particularly distressing. The presence of a palpable abdominal thrill or bruit with or without congestive heart failure should results in a high index of suspicion of this entity. Prompt recognition and surgical closure of the post-laminectomy arteriovenous iliac fistula are most important in successful management.

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Bilateral Pulmonary Sequestrations - A Case Report - (양측성 폐 격리증;1례보고)

  • 정성규
    • Journal of Chest Surgery
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    • v.25 no.10
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    • pp.1070-1075
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    • 1992
  • Bilateral intralobar and extralobar pulmonary sequestration is an extremely rare anomaly. At present, four pathologically proven cases and two possible cases have been reported in the literature insofar as we know. We have found no previous reports in the literature in which simultaneous bilateral intralobar and extralobar pulmonary sequestration were present. We report a first case presenting as bilateral intralobar and extralobar pulmonary sequestration, recently performed staged bilateral resection, and emphasize the importance of computed tomography and angiography in diagnosis and operation.

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A Case Report on the Treatment of Atypical Facial Pain (비정형성 구강안면 동통 치험예)

  • Sung-Woo Lee;Song Han
    • Journal of Oral Medicine and Pain
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    • v.20 no.1
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    • pp.127-131
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    • 1995
  • A patient who showed atypical orofacial pain after an endodontic treatment for a long time, was treated with non-analgesics such as vitamin $B_1, B_2, $ and Oral Balance, moisturizing gel. 1. It is important to manage xerostomic condition properly in the treatment of patients who have atypical orofacial pain 2. Simultaneous administration of vitamin $B_1 and B_2$ was effective in increasing pain threshold of the patient.

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