• Title/Summary/Keyword: simulation system

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Development of $^{166}Ho$-Stent for the Treatment of Esophageal Cancer (식도암 치료용 $^{166}Ho$-Stent 개발)

  • Park, Kyung-Bae;Kim, Young-Mi;Kim, Kyung-Hwa;Shin, Byung-Chul;Park, Woong-Woo;Han, Kwang-Hee;Chung, Young-Ju;Choi, Sang-Mu;Lee, Jong-Doo
    • The Korean Journal of Nuclear Medicine
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    • v.34 no.1
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    • pp.62-73
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    • 2000
  • Purpose: Esophageal cancer patients have a difficulty in the intake of meals through the blocked esophageal lumen, which is caused by an ingrowth of cancer cells and largely influences on the prognosis. It is reported that esophageal cancer has a very low survival rate due to the lack of nourishment and immunity as the result of this. In this study a new radioactive stent, which prevents tumor ingrowth and restenosis by additional radiation treatment, has been developed. Materials and Methods: Using ${\ulcorner}HANARO{\lrcorner}$ research reactor, the radioactive stent assembly ($^{166}Ho$-SA) was prepared by covering the metallic stent with a radioactive sleeve by means of a post-irradiation and pre-irradiation methods. Results: Scanning electron microscopy and autoradiography exhibited that the distribution of $^{165/166}Ho\;(NO_3)$ compounds in polyurethane matrix was homogeneous. A geometrical model of the esophagus considering its structural properties, was developed for the computer simulation of energy deposition to the esophageal wall. The dose distributions of $^{166}Ho$-stent were calculated by means of the EGS4 code system. The sources are considered to be distributed uniformly on the surface in the form of a cylinder with a diameter of 20 mm and length of 40 mm. As an animal experiment, when radioactive stent developed in this study was inserted into the esophagus of a Mongrel dog, tissue destruction and widening of the esophageal lumen were observed. Conclusion: We have developed a new radioactive stent comprising of a radioactive tubular sleeve covering the metallic stent, which emits homogeneous radiation. If it is inserted into the blocked or narrowed lumen, it can lead to local destruction of the tumor due to irradiation effect with dilatation resulting from self-expansion of the metallic property. Accordingly, it is expected that restenosis esophageal lumen by the continuous ingrowth and infiltration of cancer after insertion of our radioactive stent will be decreased remarkably.

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Quality Assurance of Patients for Intensity Modulated Radiation Therapy (세기조절방사선치료(IMRT) 환자의 QA)

  • Yoon Sang Min;Yi Byong Yong;Choi Eun Kyung;Kim Jong Hoon;Ahn Seung Do;Lee Sang-Wook
    • Radiation Oncology Journal
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    • v.20 no.1
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    • pp.81-90
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    • 2002
  • Purpose : To establish and verify the proper and the practical IMRT (Intensity--modulated radiation therapy) patient QA (Quality Assurance). Materials and Methods : An IMRT QA which consists of 3 steps and 16 items were designed and examined the validity of the program by applying to 9 patients, 12 IMRT cases of various sites. The three step OA program consists of RTP related QA, treatment information flow QA, and a treatment delivery QA procedure. The evaluation of organ constraints, the validity of the point dose, and the dose distribution are major issues in the RTP related QA procedure. The leaf sequence file generation, the evaluation of the MLC control file, the comparison of the dry run film, and the IMRT field simulate image were included in the treatment information flow procedure QA. The patient setup QA, the verification of the IMRT treatment fields to the patients, and the examination of the data in the Record & Verify system make up the treatment delivery QA procedure. Results : The point dose measurement results of 10 cases showed good agreement with the RTP calculation within $3\%$. One case showed more than a $3\%$ difference and the other case showed more than $5\%$, which was out side the tolerance level. We could not find any differences of more than 2 mm between the RTP leaf sequence and the dry run film. Film dosimetry and the dose distribution from the phantom plan showed the same tendency, but quantitative analysis was not possible because of the film dosimetry nature. No error had been found from the MLC control file and one mis-registration case was found before treatment. Conclusion : This study shows the usefulness and the necessity of the IMRT patient QA program. The whole procedure of this program should be peformed, especially by institutions that have just started to accumulate experience. But, the program is too complex and time consuming. Therefore, we propose practical and essential QA items for institutions in which the IMRT is performed as a routine procedure.

Simulation of Drying Grain with Solar-Heated Air (태양에너지를 이용한 곡물건조시스템의 시뮬레이션에 관한 연구)

  • 금동혁;김용운
    • Journal of Biosystems Engineering
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    • v.4 no.2
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    • pp.65-83
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    • 1979
  • Low-temperature drying systems have been extensively used for drying cereal grain such as shelled corn and wheat. Since the 1973 energy crisis, many researches have been conducted to apply solar energy as supplemental heat to natural air drying systems. However, little research on rough rice drying has been done in this area, especially very little in Korea. In designing a solar drying system, quality loss, airflow requirements, temperature rise of drying air, fan power and energy requirements should be throughly studied. The factors affecting solar drying systems are airflow rate, initial moisture content, the amount of heat added to drying air, fan operation method and the weather conditions. The major objectives of this study were to analyze the effects of the performance factors and determine design parameters such as airflow requirements, optimum bed depth, optimum temperature rise of drying air, fan operation method and collector size. Three hourly observations based on the 4-year weather data in Chuncheon area were used to simulate rough rice drying. The results can be summarized as follows: 1. The results of the statistical analysis indicated that the experimental and predicted values of the temperature rise of the air passing through the collector agreed well. 2. Equilibrium moisture content was affected a little by airflow rate, but affected mainly by the amount of heat added, to drying air. Equilibrium moisture content ranged from 12.2 to 13.2 percent wet basis for the continuous fan operation, from 10.4 to 11.7 percent wet basis for the intermittent fan operation respectively, in range of 1. 6 to 5. 9 degrees Centigrade average temperature rise of drying air. 3. Average moisture content when top layer was dried to 15 percent wet basis ranged from 13.1 to 13.9 percent wet basis for the continuous fan operation, from 11.9 to 13.4 percent wet basis for the intermittent fan operation respectively, in the range of 1.6 to 5.9 degrees Centigrade average temperature rise of drying air and 18 to 24 percent wet basis initial moisture content. The results indicated that grain was overdried with the intermittent fan operation in any range of temperature rise of drying air. Therefore, the continuous fan operation is usually more effective than the intermittent fan operation considering the overdrying. 4. For the continuous fan operation, the average temperature rise of drying air may be limited to 2.2 to 3. 3 degrees Centigrade considering safe storage moisture level of 13.5 to 14 perceut wet basis. 5. Required drying time decrease ranged from 40 to 50 percent each time the airflow rate was doubled and from 3.9 to 4.3 percent approximately for each one degrees Centigrade in average temperature rise of drying air regardless of the fan operation methods. Therefore, the average temperature rise of drying air had a little effect on required drying time. 6. Required drying time increase ranged from 18 to 30 percent approximately for each 2 percent increase in initial moisture content regardless of the fan operation methods, in the range of 18 to 24 percent moisture. 7. The intermittent fan operation showed about 36 to 42 percent decrease in required drying time as compared with the continuous fan operation. 8. Drymatter loss decrease ranged from 34 to 46 percent each time the airflow rate was doubled and from 2 to 3 percent approximately for each one degrees Centigrade in average temperature rise of drying air, regardless of the fan operation methods. Therefore, the average temperature rise of drying air had a little effect on drymatter loss. 9. Drymatter loss increase ranged from 50 to 78 percent approximately for each 2 percent increase in initial moisture content, in the range of 18 to 24 percent moisture. 10. The intermittent fan operation: showed about 40 to 50 percent increase in drymatter loss as compared with the continuous fan operation and the increasing rate was higher at high level of initial moisture and average temperature rise. 11. Year-to-year weather conditions had a little effect on required drying time and drymatter loss. 12. The equations for estimating time required to dry top layer to 16 and 1536 wet basis and drymatter loss were derived as functions of the performance factors. by the least square method. 13. Minimum airflow rates based on 0.5 percent drymatter loss were estimated. Minimum airflow rates for the intermittent fan operation were approximately 1.5 to 1.8 times as much as compared with the continuous fan operation, but a few differences among year-to-year. 14. Required fan horsepower and energy for the intermittent fan operation were 3. 7 and 1. 5 times respectively as much as compared with the continuous fan operation. 15. The continuous fan operation may be more effective than the intermittent fan operation considering overdrying, fan horsepower requirements, and energy use. 16. A method for estimating the required collection area of flat-plate solar collector using average temperature rise and airflow rate was presented.

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Simulation of Drying Grain with Solar-Heated Air (태양에너지를 이용한 곡물건조시스템의 시뮬레이션에 관한 연구)

  • Keum, Dong-Hyuk
    • Journal of Biosystems Engineering
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    • v.4 no.2
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    • pp.64-64
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    • 1979
  • Low-temperature drying systems have been extensively used for drying cereal grain such as shelled corn and wheat. Since the 1973 energy crisis, many researches have been conducted to apply solar energy as supplemental heat to natural air drying systems. However, little research on rough rice drying has been done in this area, especially very little in Korea. In designing a solar drying system, quality loss, airflow requirements, temperature rise of drying air, fan power and energy requirements should be throughly studied. The factors affecting solar drying systems are airflow rate, initial moisture content, the amount of heat added to drying air, fan operation method and the weather conditions. The major objectives of this study were to analyze the effects of the performance factors and determine design parameters such as airflow requirements, optimum bed depth, optimum temperature rise of drying air, fan operation method and collector size. Three hourly observations based on the 4-year weather data in Chuncheon area were used to simulate rough rice drying. The results can be summarized as follows: 1. The results of the statistical analysis indicated that the experimental and predicted values of the temperature rise of the air passing through the collector agreed well.2. Equilibrium moisture content was affected a little by airflow rate, but affected mainly by the amount of heat added, to drying air. Equilibrium moisture content ranged from 12.2 to 13.2 percent wet basis for the continuous fan operation, from 10.4 to 11.7 percent wet basis for the intermittent fan operation respectively, in range of 1. 6 to 5. 9 degrees Centigrade average temperature rise of drying air.3. Average moisture content when top layer was dried to 15 percent wet basis ranged from 13.1 to 13.9 percent wet basis for the continuous fan operation, from 11.9 to 13.4 percent wet basis for the intermittent fan operation respectively, in the range of 1.6 to 5.9 degrees Centigrade average temperature rise of drying air and 18 to 24 percent wet basis initial moisture content. The results indicated that grain was overdried with the intermittent fan operation in any range of temperature rise of drying air. Therefore, the continuous fan operation is usually more effective than the intermittent fan operation considering the overdrying.4. For the continuous fan operation, the average temperature rise of drying air may be limited to 2.2 to 3. 3 degrees Centigrade considering safe storage moisture level of 13.5 to 14 perceut wet basis.5. Required drying time decrease ranged from 40 to 50 percent each time the airflow rate was doubled and from 3.9 to 4.3 percent approximately for each one degrees Centigrade in average temperature rise of drying air regardless of the fan operation methods. Therefore, the average temperature rise of drying air had a little effect on required drying time.6. Required drying time increase ranged from 18 to 30 percent approximately for each 2 percent increase in initial moisture content regardless of the fan operation methods, in the range of 18 to 24 percent moisture.7. The intermittent fan operation showed about 36 to 42 percent decrease in required drying time as compared with the continuous fan operation.8. Drymatter loss decrease ranged from 34 to 46 percent each time the airflow rate was doubled and from 2 to 3 percent approximately for each one degrees Centigrade in average temperature rise of drying air, regardless of the fan operation methods. Therefore, the average temperature rise of drying air had a little effect on drymatter loss. 9. Drymatter loss increase ranged from 50 to 78 percent approximately for each 2 percent increase in initial moisture content, in the range of 18 to 24 percent moisture. 10. The intermittent fan operation: showed about 40 to 50 percent increase in drymatter loss as compared with the continuous fan operation and the increasing rate was higher at high level of initial moisture and average temperature rise.11. Year-to-year weather conditions had a little effect on required drying time and drymatter loss.12. The equations for estimating time required to dry top layer to 16 and 1536 wet basis and drymatter loss were derived as functions of the performance factors. by the least square method.13. Minimum airflow rates based on 0.5 percent drymatter loss were estimated.Minimum airflow rates for the intermittent fan operation were approximately 1.5 to 1.8 times as much as compared with the continuous fan operation, but a few differences among year-to-year.14. Required fan horsepower and energy for the intermittent fan operation were3. 7 and 1. 5 times respectively as much as compared with the continuous fan operation.15. The continuous fan operation may be more effective than the intermittent fan operation considering overdrying, fan horsepower requirements, and energy use.16. A method for estimating the required collection area of flat-plate solar collector using average temperature rise and airflow rate was presented.

The Development of Estimation Model (AFKAE0.5) for Water Balance and Soil Water Content Using Daily Weather Data (일별 기상자료를 이용한 농경지 물 수지 및 토양수분 예측모형 (AFKAE0.5) 개발)

  • Seo, Myung-Chul;Hur, Seung-Oh;Sonn, Yeon-Kyu;Cho, Hyeon-Suk;Jeon, Weon-Tai;Kim, Min-Kyeong;Kim, Min-Tae
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.6
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    • pp.1203-1210
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    • 2012
  • As the area of upland crops increase, it is become more important for farmers to understand status of soil water at their own fields due to key role of proper irrigation. In order to estimate daily water balance and soil water content with simple weather data and irrigation records, we have developed the model for estimating water balance and soil water content, called AFKAE0.5, and verified its simulated results comparing with daily change of soil water content observed by soil profile moisture sensors. AFKAE0.5 has two hypothesis before establishing its system. The first is the soil in the model has 300 mm in depth with soil texture. And the second is to simplify water movement between the subjected soil and beneath soil dividing 3 categories which is defined by soil water potential. AFKAE0.5 characterized with determining the amount of upward and downward water between the subjected soil and beneath soil. As a result of simulation of AFKAE0.5 at Gongju region with red pepper cultivation in 2005, the water balance with input minus output is recorded as - 88 mm. the amount of input water as precipitation, irrigation, and upward water is annually 1,043, 0, and 207 mm, on the other, output as evapotranspiration, run-off, and percolation is 831, 309, and 161 mm, respectively.

Process Design of Carbon Dioxide Storage in the Marine Geological Structure: I. Comparative Analysis of Thermodynamic Equations of State using Numerical Calculation (이산화탄소 해양지중저장 처리를 위한 공정 설계: I. 수치계산을 통한 열역학 상태방정식의 비교 분석)

  • Huh, Cheol;Kang, Seong-Gil
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.11 no.4
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    • pp.181-190
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    • 2008
  • To response climate change and Kyoto protocol and to reduce greenhouse gas emissions, marine geological storage of $CO_2$ is regarded as one of the most promising option. Marine geological storage of $CO_2$ is to capture $CO_2$ from major point sources(eg. power plant), to transport to the storage sites and to store $CO_2$ into the marine geological structure such as deep sea saline aquifer. To design a reliable $CO_2$ marine geological storage system, it is necessary to perform numerical process simulation using thermodynamic equation of state. The purpose of this paper is to compare and analyse the relevant equations of state including ideal, BWRS, PR, PRBM and SRK equation of state. To evaluate the predictive accuracy of the equation of the state, we compared numerical calculation results with reference experimental data. Ideal and SRK equation of state did not predict the density behavior above $29.85^{\circ}C$, 60 bar. Especially, they showed maximum 100% error in supercritical state. BWRS equation of state did not predict the density behavior between $60{\sim}80\;bar$ and near critical temperature. On the other hand, PR and PRBM equation of state showed good predictive capability in supercritical state. Since the thermodynamic conditions of $CO_2$ reservoir sites correspond to supercritical state(above $31.1^{\circ}C$ and 73.9 bar), we conclude that it is recommended to use PR and PRBM equation of state in designing of $CO_2$ marine geological storage process.

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Process Design of Carbon Dioxide Storage in the Marine Geological Structure: II. Effect of Thermodynamic Equations of State on Compression and Transport Process (이산화탄소 해양지중저장 처리를 위한 공정 설계: II. 열역학 상태방정식이 압축 및 수송 공정에 미치는 영향 평가)

  • Huh, Cheol;Kang, Seong-Gil
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.11 no.4
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    • pp.191-198
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    • 2008
  • To design a reliable $CO_2$ marine geological storage system, it is necessary to perform numerical process simulation using thermodynamic equation of state. $CO_2$ capture process from the major point sources such as power plants, transport process from the capture sites to storage sites and storage process to inject $CO_2$ into the deep marine geological structure can be simulate with numerical modeling. The purpose of this paper is to compare and analyse the relevant equations of state including ideal, BWRS, PR, PRBM and SRK equation of state. We also studied the effect of thermodynamic equation of state in designing the compression and transport process. As a results of comparison of numerical calculations, all relevant equation of state excluding ideal equation of state showed similar compression behavior in pure $CO_2$. On the other hand, calculation results of BWRS, PR and PRBM showed totally different behavior in compression and transport process of captured $CO_2$ mixture from the oxy-fuel combustion coal-fired plants. It is recommended to use PR or PRBM in designing of compression and transport process of $CO_2$ mixture containing NO, Ar and $O_2$.

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Combustion Characteristic Study of LNG Flame in an Oxygen Enriched Environment (산소부화 조건에 따른 LNG 연소특성 연구)

  • Kim, Hey-Suk;Shin, Mi-Soo;Jang, Dong-Soon;Lee, Dae-Geun
    • Journal of Korean Society of Environmental Engineers
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    • v.29 no.1
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    • pp.23-30
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    • 2007
  • The ultimate objective of this study is to develop oxygen-enriched combustion techniques applicable to the system of practical industrial boiler. To this end the combustion characteristics of lab-scale LNG combustor were investigated as a first step using the method of numerical simulation by analyzing the flame characteristics and pollutant emission behaviour as a function of oxygen enrichment level. Several useful conclusions could be drawn based on this study. First of all, the increase of oxygen enrichment level instead of air caused long and thin flame called laminar flame feature. This was in good agreement with experimental results appeared in open literature and explained by the effect of the decrease of turbulent mixing due to the decrease of absolute amount of oxidizer flow rate by the absence of the nitrogen species. Further, as expected, oxygen enrichment increased the flame temperatures to a significant level together with concentrations of $CO_2$ and $H_2O$ species because of the elimination of the heat sink and dilution effects by the presence of $N_2$ inert gas. However, the increased flame temperature with $O_2$ enriched air showed the high possibility of the generation of thermal $NO_x$ if nitrogen species were present. In order to remedy the problem caused by the oxygen-enriched combustion, the appropriate amount of recirculation $CO_2$ gas was desirable to enhance the turbulent mixing and thereby flame stability and further optimum determination of operational conditions were necessary. For example, the adjustment of burner with swirl angle of $30\sim45^{\circ}$ increased the combustion efficiency of LNG fuel and simultaneously dropped the $NO_x$ formation.

Estimation of Spatial Accumulation and transportation of Chl-$\alpha$ by the Numerical Modeling in Red Tide of Chinhae Bay (진해만 적조에 있어서 수치모델링에 의한 Chl-$\alpha$의 공간적 집적과 확산 평가)

  • Lee Dae-In
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.7 no.1
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    • pp.1-12
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    • 2004
  • The summer distribution of $Cha-{alpha}$ and physical processes for simulating outbreak region of red tide were estimated by the Eco-Hydrodynamic model in Chinhae Bay. As a result of simulation of surface residual currents, the southward flow come in contact with the northward flow at the inlet and western part of bay in case of windlessness and below wind velocity 2 m/sec. As wind velocity increases, the velocity and direction of currents were fairly shifted. The predicted concentration of $Cha-{alpha}$ exceeded 20 mg/㎥ in Masan and Haengam Bays, and most regions were over 10 mg/㎥, which meant the possibility of red tide outbreak. From the results of the contributed physical processes to $Cha-{alpha}$, accumulation sites were distributed at the northern part of Kadok channel, around the Chilcheon island, the western part of Kajo island and some area of Chindong Bay. On the other hand, inner parts of the study area such as Masan Bay were estimated as the sites of strong algal activities. Masan and Haengam Bay are considered as the initial outbreak region of red tide by the modeling and observed data, and then red tide expanded to other areas such as physical accumulation region and western inner bay, as depending on environmental variation. The increase of wind velocity led to decrease of $Cha-{alpha}$ and enlargement of accumulation region. The variation of intensity of radiation and sunshine duration caused to rapidly fluctuation of $Cha-{alpha}$: however, it was not largely affected by the variation of pollutant loads from the land only.

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A Study on Developing a Model for Cancer Damage Cost Due to Risk from Benzene in Ulsan Metropolitan City (울산 지역에서 대기중 벤젠으로 인한 암 사망 손실비용 추정 모형에 관한 연구)

  • Lee, Yong-Jin;Kim, Ye-Shin;Shin, Dong-Chun;Shin, Young-Chul
    • Environmental and Resource Economics Review
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    • v.13 no.1
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    • pp.49-82
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    • 2004
  • The study aimed to evaluate cancer damage cost due to risk from benzene inhalation. We performed health risk assessment based on US EPA guideline to estimate annual population risk in Ulsan metropolitan city. Also, we estimated a willingness-to-pay amount for reducing a cancer mortality rate to evaluate a value of statistical life. We combined the annual population risk and the value of statistical life to calculate the cancer damage cost. In the health risk assessment, we applied the benzene unit risk ($2.2{\times}10^{-6}{\sim}7.8{\times}10^{-6}$) in the US EPA'S Integrated Risk Information System to assess the annual population risk. Average concentration of benzene in ambient air is $7.88{\mu}g/m^3$(min: 1.16~max: $23.32{\mu}g/m^3$). We targeted an exposure population of 516,641 persons who aged over 30 years old. Using a Monte-Carlo simulation for uncertainty analysis, we evaluated that the population risk of benzene during ten years in Ulsan city is 2.90 persons (5 percentile: 0.32~95 percentile: 9.11persons). And the monthly average WTP for 5/1,000 cancer mortality reduction during ten years is 14,852 Won(95% C.I: 13,135~16,794 Won) and the implied VSL is 36 million Won(95% C.I: 30~40 million Won). Cancer damage cost due to risk from benzene inhalation during 10 years in Ulsan city is about 104 million Won(5 percentile: 13~95 percentile: 328 million Won). Health benefit cost to reduce a cancer mortality risk of benzene is about 50 million Won is Ulsan metropolitann city. But, it is very important that this cost is not for all health damage cost of cancer mortality in some area. We just recommended a model for evaluating a cancer risk reduction, so we must re-evaluate an integrated application of total VOCs damage cost including benzene.

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