Choi, Byugchul;Kim, Jon-Ho;Kim, Jon Beom;Jung, Woonam;Lee, Sang-Hyun
Journal of Institute of Convergence Technology
/
v.8
no.1
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pp.21-25
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2018
We developed nano-porous $TiO_2-SiO_2$ composites (commercial name : PTI, porous titania insulator) with low thermal conductivity as thermal insulating material as well as function of photocatalyst. The objectives of this paper are, firstly, to evaluate of the thermal conductivity of the PTI powder in the temperature range from -160 to $250^{\circ}C$, secondly to evaluate of thermal conductivities of insulation materials that is applied PTI powder. The structure of the PTI powder that has the pores size of 20-30 nm and the particle diameter of 2-10 nm. The PTI had a high surface area of $400m^2/g$ and a mean pore size of $45{\AA}$, which was fairly uniform. The thermal conductivity was measured by GHP(guarded hot plate) method and HFM(heat flux method). The PTI structure is a three-dimensional network nano-structures composed by a pearl-necklace that involved a precious stone in the center of the necklace. The thermal conductivities of PTI-PX powder by the GHP and HFM were 0.0366 W/m.K, 0.0314 W/m.K at $20^{\circ}C$, respectively. This is similar to values that are proportional to the square of the absolute temperature of the thermal conductivity of static air. The thermal conductivities of insulating sheets coated with PTI powder were similar results with that of the PTI powder.
BACKGROUND/OBJECTIVES: Propolis has a rich source of bioactive compounds and has renal and hepatic protective properties. The purpose of this study was to investigate the beneficial effect of hydro-ethanolic extract of propolis against paracetamol-induced liver damage and impairment of kidney function, as well as hematological changes in rats. MATERIALS/METHODS: Six groups of rats were used; the first group was served as a control; the second and third groups were treated by propolis extract at a dose of 50 and 100 mg/kg.B.WT. respectively; the fourth group was treated by paracetamol (200 mg/kg.B.WT.); the fifth group was treated by propolis (50 mg/kg.B.WT.) for eight days and then received similar dose of propolis for following seven days with paracetamol at a dose of 200 mg/kg.B.WT. daily for the seven days; and the sixth group was treated with propolis (100 mg/kg.B.WT.) for eight days and then received similar dose of propolis for following seven days with paracetamol at a dose of 200 mg/kg.B.WT. daily for the seven days. All the animals were treated for a period of 15 days. At the end of the experimental period, blood samples were collected for measurement of the liver enzymes, serum albumin, protein and creatinine, blood urea nitrogen, hematological parameters, and urine volume, protein and albumin. RESULTS: Paracetamol over dose significantly lowered hemoglobin, serum total protein, albumin, and uric acid, while it significantly increased blood creatinine, blood urea nitrogen, alanine aminotransferase, aspartate aminotransferase and lactate dehydrogenase activities, white blood cells, and platelet count as compared to the control. However, these alterations were significantly attenuated by the use of propolis extract and the effect was dose dependent. Interestingly, propolis prevented paracetamol induced proteinuria, low hemoglobin and body weight loss. CONCLUSIONS: Propolis significantly prevented paracetamol induced renal, hepatic and hematological toxicity and might be useful in the management of liver and renal diseases particularly proteinuria.
Min, Jee Young;Ko, Sung Min;Song, In Young;Yi, Jung Geun;Hwang, Hweung Kon;Shin, Je Kyoun
Korean Journal of Radiology
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v.19
no.6
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pp.1007-1020
/
2018
Objective: To compare the diagnostic performance of cardiovascular magnetic resonance (CMR) myocardial perfusion at 1.5- and 3-tesla (T) for detecting significant coronary artery disease (CAD), with invasive coronary angiography (ICA) as the reference method. Materials and Methods: We prospectively enrolled 281 patients (age $62.4{\pm}8.3$ years, 193 men) with suspected or known CAD who had undergone 1.5T or 3T CMR and ICA. Two independent radiologists interpreted perfusion defects. With ICA as the reference standard, the diagnostic performance of 1.5T and 3T CMR for identifying significant CAD (${\geq}50%$ diameter reduction of the left main and ${\geq}70%$ diameter reduction of other epicardial arteries) was determined. Results: No differences were observed in baseline characteristics or prevalence of CAD and old myocardial infarction (MI) using 1.5T (n = 135) or 3T (n = 146) systems. Sensitivity, specificity, positive and negative predictive values, and area under the receiver operating characteristic curve (AUC) for detecting significant CAD were similar between the 1.5T (84%, 64%, 74%, 76%, and 0.75 per patient and 68%, 83%, 66%, 84%, and 0.76 per vessel) and 3T (80%, 71%, 71%, 80%, and 0.76 per patient and 75%, 86%, 64%, 91%, and 0.81 per vessel) systems. In patients with multi-vessel CAD without old MI, the sensitivity, specificity, and AUC with 3T were greater than those with 1.5T on a per-vessel basis (71% vs. 36%, 92% vs. 69%, and 0.82 vs. 0.53, respectively). Conclusion: 3T CMR has similar diagnostic performance to 1.5T CMR in detecting significant CAD, except for higher diagnostic performance in patients with multi-vessel CAD without old MI.
An experimental study was conducted to evaluate the dynamic behavior of a free-standing frame equipped with a movable base system using cast iron and mortar as the bearing materials. The preliminary friction test indicated that a graphite layer developed on the interface and exhibited stable friction behavior. The friction coefficient ranged from 0.33 to 0.36 when the applied normal compression stress ranged from 2.6 to 5.2 MPa. The effect of the variation of normal compression stress would be small. Shaking table tests on the free-standing frame showed that rock, slide, and rock-slide responses occurred. The cumulative slide distance reached 381 mm under JMA Kobe wave excitation; however, only a few cyclic slides occurred at the same locations along the moving track. Most surfaces sustained single slides. Similar results can be observed in other shaking conditions. The insufficient cyclic sliding and significant rocking resulted in a few graphite layers on the mortar surfaces. Friction coefficients were generally similar to those obtained in the preliminary friction tests; however, the values fluctuated when the rocking became significant. The collisions due to rocking caused strong horizontal acceleration responses and resulted in high friction coefficient. In addition, the strong horizontal acceleration responses caused by the collisions made the freestanding specimen unable to reduce the input horizontal acceleration notably, even when slippage occurred. Compared with the counterpart fixed-base specimen, the specimen equipped with the iron-mortar base could reduce the horizontal acceleration amplification response and the structural deformation, whereas the vertical acceleration response was doubled due to collisions from rocking.
Alhossaini, Rana M.;Altamran, Abdulaziz A.;Choi, Seohee;Roh, Chul-Kyu;Seo, Won Jun;Cho, Minah;Son, Taeil;Kim, Hyung-Il;Hyung, Woo Jin
Journal of Gastric Cancer
/
v.19
no.2
/
pp.165-172
/
2019
Purpose: The robotic system for surgery was introduced to gastric cancer surgery in the early 2000s to overcome the shortcomings of laparoscopic surgery. The more recently introduced da Vinci $Xi^{(R)}$ system offers benefits allowing four-quadrant access, greater range of motion, and easier docking through an overhead boom rotation with laser targeting. We aimed to identify whether the $Xi^{(R)}$ system provides actual advantages over the $Si^{(R)}$ system in gastrectomy for gastric cancer by comparing the operative outcomes. Materials and Methods: We retrospectively reviewed all patients who underwent robotic gastrectomy as treatment for gastric cancer from March 2016 to March 2017. Patients' demographic data, perioperative information, and operative and pathological outcomes were collected and analyzed. Results: A total of 109 patients were included in the $Xi^{(R)}$ group and 179 in the $Si^{(R)}$ group. Demographic characteristics were similar in both groups. The mean operative time was 229.9 minutes in the $Xi^{(R)}$ group and 223.7 minutes in the $Si^{(R)}$ group. The mean estimated blood loss was 72.7 mL in the $Xi^{(R)}$ group and 62.1 mL in the $Si^{(R)}$ group. No patient in the $Xi^{(R)}$ group was converted to open or laparoscopy, while 3 patients in the $Si^{(R)}$ group were converted, 2 to open surgery and 1 to laparoscopy, this difference was not statistically significant. Bowel function was resumed 3 days after surgery, while soft diet was initiated 4 days after surgery. Conclusions: We found no difference in surgical outcomes after robotic gastrectomy for gastric cancer between the da Vinci $Xi^{(R)}$ and da Vinci $Si^{(R)}$ procedures.
Journal of the Korean Association of Oral and Maxillofacial Surgeons
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v.47
no.2
/
pp.91-98
/
2021
Objectives: Hyaluronoglucosaminidase (hyaluronidase) increases the local intercellular permeability of the peripheral lymphatic channel and capillaries, which may help reduce edema. In the present study, the effects of hyaluronidase on postoperative edema and pain reduction were evaluated. Materials and Methods: The study included 38 patients who underwent guided bone regeneration (GBR) surgery before implantation. Patients were randomly assigned to either the control group (n=20) or the test group (n=18). Hyaluronidase was injected into the GBR site of subjects in the test group. Postoperative edema was evaluated by measuring the distance between specific facial landmarks immediately after surgery (T1) and 2-4 days after surgery (T2). The degree of pain at T2 and at 10-14 days after surgery (T3) was assessed. Results: In the test group, the degree of swelling was lower than in the control group, however, only two measurements, from the tragus to the mouth corner and from the outer canthus to the mouth corner, showed statistically significant differences (P=0.012 and P=0.001, respectively). The anti-edema effect of hyaluronidase was more effective in the maxilla than in the mandible. In the maxilla, the percentage of facial swelling was significant for three measurements. However, in the mandible, the percentage of facial swelling was significant for only one measurement. Low levels of pain that were similar at T2 and T3 were reported in both groups. Conclusion: The results indicate the degree of swelling was lower in the test group and hyaluronidase appeared to be more effective in the maxilla. The degree of pain reduction was similar between groups. Further in vivo and randomized controlled trials with larger sample sizes are warranted.
Journal of the Architectural Institute of Korea Planning & Design
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v.34
no.8
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pp.51-58
/
2018
G-SEED has been introduced with the aim of reducing energy use and resources since 2002, as the system of certificating environmental friendliness of buildings to create comfortable environment. This study analyzed the changes of certification standard of G-SEED since the revision in 2016, comparing certification results of office buildings by grade, category and certification items between G-SEED 2013-2 version and revised version of 2016. Also, this study analyzed the average points and their standard deviation of certification items including both deleted items and newly added items and extracted items needed to be reviewed in the future revision. In the revision, G-SEED has been extended its certification system to involve existing buildings and Innovative Design categories newly introduced with revising the certification items and difficulties. In revised version of G-SEED, the certification grade appeared to change its acquisition ratio decreasing Green2 and increasing Green4, during Green1 and Green3 were similar in proportion. The average scores by categories appeared decrease in Energy and Environmental Pollution category and Materials and Resources category, on the other hand, Maintenance category appeared the highest increase in the average score. Otherwise, Land Use and Transportation, Water Circulation, Ecology, Indoor Environment categories appeared similar average scores both version of G-SEED. In addition, the Innovative Design which was newly introduced category, seems to expect gradual gaining high scores according to technology development in future, although its possession has shown lower scores in revised version.
Mun, In Kwon;Yoo, Won Sang;Lee, Sang Joon;Chung, Phil-Sang;Woo, Seung Hoon
Medical Lasers
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v.10
no.1
/
pp.37-44
/
2021
Background and Objectives Hypothyroidism is the most common endocrine disease. On the other hand, there is no treatment that can improve the thyroid function. Low-level laser therapy (LLLT) can improve the cellular activity. The effect of hypothyroidism is not obvious. This study examined the effects of LLLT on the thyroid gland function of a propylthiouracil (PTU)-induced hypothyroidism mouse model. Materials and Methods Twenty-five male ICR mice were distributed into five groups of five animals each: Negative control (none PTU animal) and positive control (PTU animal) of unirradiated animals, and three experimental groups with LLLT (3J, 6J, and 12J). Each mouse was exposed to a distinct dose of a 632-nm laser once a week for three rounds. The positive control group and three LLLT groups were induced into a hypothyroidism state by PTU administration. The animals' thyroid-stimulating hormone and thyroxine levels were measured using an ELISA kit, and their thyroid tissue was harvested and analyzed after sacrifice at the end of the experiment. The hormone level and morphological changes in the tissue of the five groups were compared. Results The thyroid hormone levels in the control group and LLLT groups were similar. On the other hand, the thyroid tissue of the LLLT groups showed some morphological changes that were similar to those of iodine deficiency thyroid. Conclusion LLLT did not affect the thyroid gland function in PTU-induced hypothyroidism mice.
Ji, Yoon-Sun;Lee, Nam-Sun;Kil, Ki-Jung;Yoo, Ji-Hyun
The Korea Journal of Herbology
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v.34
no.1
/
pp.109-116
/
2019
Objectives : This study aimed to analyze contents of chlorogenic acid among major ingredients and determine the optimal solvent for the antioxidant activity from Solidago virga-aurea var. gigantea(SV) aerial part. Methods : Mature aerial part of extracted SV at the first crop on June 2018 was used. SV was mixed with each at the ethanol concentrate rates of water, 10, 30, 50, 70, and 100% and extracted them for three times for eight hours at $70^{\circ}C$. The contents of chlorogenic acid and seven kinds of antioxidant activities were measured in SV extracts. Results : The highest the contents of chlorogenic acid was from 10% ethanol extracts showed. Total polyphenol and flavonoids of SV extracts were 126.16 mg/g and 105.84 mg/g, respectively. Scavenging activities of DPPH, ABTS, and hydroxyl radical significantly increased in a dose-dependent in SV extracts, while it was almost similar with control at the concentration of $500{\mu}g/mL$. $Fe^{2+}$ chelating activity significantly increase in a dose-dependent in SV extract, it was lower than control. Nitrite scavenging activity increased, dose-dependent in the sequence of pH 1.2> pH 3.0 > pH 6.0 in SV extracts, while it was almost similar with control at the concentration of $500{\mu}g/mL$, pH 1.2, and pH 3.0. Conclusions : Thus, this study found that higher contents of chlorogenic acid and excellent antioxidant activity were contained in 10% ethanol extracts in mature aerial part of SV. It is expected to be used as basic data as natural antioxidant materials.
This study investigated the stone Angbu-ilgu (scaphe sundial) of the Korea Meteorological Administration (KMA) and the Seoul Museum of History (SMH). Since the first Angbu-ilgu was produced in Korea in 1434 (the year of the reign of King Sejong), Angbu-ilgu has been reproduced with various materials. The upper surface of these two stone Angbu-ilgus symbolizes the horizon. On the hemisphere concave at the center of the horizon, the South Pole, the time line, and the season line are engraved. On the horizon of both the KMA and SMH Angbu-ilgus, the schematic, typeface, and composition of the inscription completely coincide with each other. In this study, it was estimated that the appearance of the KMA Angbu-ilgu, which was damaged at some point previously at least once, was similar to that of the SMH Angbu-ilgu, and this means that it is superficially similar with Treasure No 840, the stone horizontal sundial. In the concave hemisphere of both the stone Angbu-ilgus of the KMA and SMH, there are hour lines and 24 solar-term lines (13 line), and there is an intersection point where these lines meet the horizon, respectively. It can be verified that these intersections of these two Angbu-ilgus can be calculated as having a latitude of +37°39'15". The hour lines of the two stone Angbu-ilgus show that they were made after about 1900.
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