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Slow release of microencapsulated model compounds of insect pheromone using low molecular weight polyethylene and urea-formaldehyde resin (저분자량 polyethylene과 urea-formaldehyde 수지를 이용한 microencapsulation에 의한 곤충 페로몬의 model 화합물들의 slow release)

  • Kim, Jung-Han;Oh, Won-Taek;Kim, Yong-Jin
    • Applied Biological Chemistry
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    • v.34 no.2
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    • pp.110-116
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    • 1991
  • As the model compounds, citral and n-octanol which possess similar characteristics and structures of low molecular weight insect pheromones and $({\pm})-5-hydroxy-4-methyl-heptan-3-one$ which shows the aggregation pheromones activity of the rice weevil and the maize weevil were microencapsulated with low molecular weight polyethylene(LMPE) and urea-formaldehyde resin as wall materials. The core materials were microencapsulated as small particles in LMPE and urea-formaldehyde resin polymers and the microencapsulated polymers were white powders. And the polymer made from urea-formaldehyde resin was better than that from LMPE as wall material. The slow releasing effect and the releasing patten of the microencapsulated core materials were examined by solvent extraction method and headspace sampling method. Citral and n-octanol and $({\pm})-5-hydroxy-4-methyl-heptan-3-one$ were release more than 40 days and 15 days, respectively. The releasing pattern of urea-formaldehyde resin microcapsules showed rather smooth decrease than that of LMPE and was maintained at steady level longer.

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A Study on the Golf Slacks Pattern for Women in 40's (40대 여성 골퍼를 위한 슬랙스 패턴 설계에 관한 연구)

  • Lee, Hyo-Jung;Ryu, Sin-A;Park, Kil-Soon
    • Fashion & Textile Research Journal
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    • v.13 no.1
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    • pp.116-129
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    • 2011
  • The purpose of this study is to research on changes of body surface according to golf movements in designs of golf slacks pattern and reflect it to designs of golf slacks pattern to enhance adaptability. For the first stage of this study, length of body surface was analyzed by using 3D body shape. In second stage, analysis of wearing test of golf slacks is performed to extract major pattern design factor of golf slacks and then research patterns were designed. In third stage, 4 differently designed 1st, 2nd slacks were used for analysis of 3D Clothing air volume. The results of this research is as follow. The variation rate of body surface length according to golf swing posture resulted the longest on back swing posture and follow through posture. Waist circumference-omphalion, thigh and ankle circumference increased more than 10% of body surface during golf swing. Front waist circumference-omphalion, right waist to hip length, left waist to hip length and right back center length were decreased more than 10%. As a result of analysis on measurements of 1st slacks pattern design, waist front center getting in values, waist front center going down value, front hip width, and front crotch extension had similar industrial pattern design. Back center line angle, back crotch extension, and knee center point~back waist center point had significant differences. The designs and ease proposed for golf slacks pattern in this study are waist circumference 75.5 cm(1.8 cm, 2.38%), hip circumference 95 cm(2 cm, 2.11%), crotch length(front: -0.8 cm, -1.25%; rear: -1.8 cm, -2.83%), slacks length 96c m, gradient of C.B.L $10^{\circ}$, crotch extension (back 9.2~10.4 cm, front 3.2 cm).

Spindle cell lipoma of the posterior neck: A case report (목뒤부위에 발생한 방추세포 지방종의 치험례)

  • Park, Sun Hee;Yim, Young Min;Jung, Sung No;Kwon, Ho
    • Archives of Plastic Surgery
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    • v.36 no.2
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    • pp.233-236
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    • 2009
  • Purpose: Spindle cell lipoma(SCL) is an uncommon subcutaneous soft tissue neoplasm that arises in the shoulder and posterior neck of older male patients. The imaging appearance of SCL is not pathognomonic and can display some features overlapping with liposarcoma. We report a case of SCL on the posterior neck. Method: The patient is a 50 - year - old man with a slowly enlarging subcutaneous mass on the right side of posterior neck. Computed tomographic imaging revealed a 7.0 cm sized, well - circumscribed, heterogenous and fatty mass with enhanced solid components. Whole body Fluorine - 18 Fluorodeoxyglucose Positron emission tomogram(FDG PET-CT) showed little increase of FDG uptake on the right posterior neck and there was no distant metastasis. Results: The mass was surgically removed. The resection margin was free of tumor on frozen biopsy. Histopathologic examination indicated spindle cell lipoma consisting of a mixture of mature adipocytes and uniform spindle cells within a matrix of mucinous material. Conclusion: Although CT image of solidtary mass in posterior neck is similar with the one of liposarcoma, we should consider that it may be a spindle cell lipoma if PET-CT and other systemic studies reveal no distant metastasis. And we should perform fine needle aspiration to differentiate SCL from malignant lesions.

Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K

  • Kim, Ji Ho;Son, Yeon Kyung;Kim, Gun Hee;Hwang, Keum Hee
    • Biomolecules & Therapeutics
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    • v.21 no.3
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    • pp.234-240
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    • 2013
  • Monoamine oxidase inhibitors (MAOI) have been widely used as antidepressants. Recently, there has been renewed interest in MAO inhibitors. The activity-guided fractionation of extracts from Angelica keiskei Koidzumi (A. keiskei K.) led to the isolation of two prenylated chalcones, xanthoangelol and 4-hydroxyderricin and a flavonoid, cynaroside. These three isolated compounds are the major active ingredients of A. keiskei K. to inhibit the MAOs and DBH activities. Xanthoangelol is a nonselective MAO inhibitor, and a potent dopamine ${\beta}$-hydroxylase (DBH) inhibitor. $IC_{50}$ values of xanthoangelol to MAO-A and MAO-B were calculated to be 43.4 ${\mu}M$, and 43.9 ${\mu}M$. These values were very similar to iproniazid, which is a nonselective MAO inhibitor used as a drug against depression. The $IC_{50}$ values of iproniazid were 37 ${\mu}M$, and 42.5 ${\mu}M$ in our parallel examination. Moreover, $IC_{50}$ value of xanthoangelol to DBH was calculated 0.52 ${\mu}M$. 4-Hydroxyderricin is a potent selective MAO-B inhibitor and also mildly inhibits DBH activity. The $IC_{50}$ value of 4-hydroxyderricin to MAO-B was calculated to be 3.43 ${\mu}M$ and this value was higher than that of deprenyl (0.046 ${\mu}M$) used as a positive control for selective MAO-B inhibitor in our test. Cynaroside is a most potent DBH inhibitor. The $IC_{50}$ value of cynaroside to DBH was calculated at 0.0410 ${\mu}M$. Results of this study suggest that the two prenylated chalcones, xanthoangelol and 4-hydroxyderricin isolated from A. keiskei K., are expected for potent candidates for development of combined antidepressant drug. A. keiskei K. will be an excellent new bio-functional food material that has the combined antidepressant effect.

Study on the Improvement of Weld-joint Reliability in Waterwall Tubes of the Ultra Supercritical Coal Fired Boiler (석탄화력발전용 초초임계압(USC) 보일러 수냉벽 튜브 용접 신뢰성 향상에 대한 연구)

  • Ahn, Jong-Seok;Lee, Seung-Hyun;Cho, Sang-Kie;Lee, Gil-Jae;Lee, Chang-Hee;Moon, Seung-Jae
    • Journal of Welding and Joining
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    • v.28 no.1
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    • pp.41-46
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    • 2010
  • The low alloy-steel material(1.0Cr-0.5Mo, SA213T12), which has widely been used for the waterwall tube in the conventional power plant, do not have enough creep rupture strength for waterwall tubes of the Ultra-supercritical(USC) boilers. According to this reason, the high-strength low alloy-steel(2.25Cr-1.0Mo, SA213T22) has newly been adopted for the waterwall tube in the USC boilers. This paper presents failure analysis on weld-joint of the waterwall tubes in USC boilers. Visual inspections were performed to find out the characteristics of the fracture. Additionally both microscopic characteristics and hardness test were carried out on failed tube samples. Failures seem to happen mainly because the welding process has not been conducted strictly.(preheating, P.W.H.T and so forth). Thus, this paper has the purpose to describe the main cause of the poor welding process and to explain how to prevent similar failures in those weld-joints.

Analysis of Natural Organic Matter (NOM) Characteristics in the Geum River (금강 수계 자연유기물 특성 분석)

  • Yu, Soon-Ju;Kim, Chang-Soo;Ha, Sung-Ryong;Hwang, Jong-Yeon;Chae, Min-Hee
    • Journal of Korean Society on Water Environment
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    • v.21 no.2
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    • pp.125-131
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    • 2005
  • Natural organic matter(NOM) is defined as the complex matrix of organic material and abundant in natural waters. It affects the performance of unit operations for water purification. Several kinds of analytical indicators such as DOC, specific ultraviolet absorbance(SUVA), apparent molecular weight (AMW), fractionation and high performance size exclusive chromatography(HPSEC) have been used to understand characteristics and variations of NOM. This study aims to evaluate the characteristics of NOM in the Geum River system comprising with stream flows and reservoirs. It was identified that SUVA denoting the portion of humic substance in water ranged within 1.60~3.36. Using resin adsorbents, dissolved organic carbon(DOC) was fractionated into three classes: hydrophobic bases(HOB), hydrophobic acids(HOA) and hydrophilic substances(HI). HI dominates in all samples, collectively accounting for more than 62% of the DOC. HOA was the second dominated fraction and it varied considerably but accounted for about 30% of the DOC. The distribution of high molecular weight(HMW) measured by HPSEC being used to determine the molecular weight distribution of aquatic humic substances was 40.1% and 38.7% in reservoir and stream flow, respectively. The distribution of low molecular weight(LMW) in stream flow was 13.2% higher than that in reservoir. And apparent molecular weight less than 1KDa, which include the molecular weight of hydrophilic organic matter, occupied with 69.2% and 68.2% in stream flow and reservoir, respectively. While the molecular weight of 1 to 100 KDa including humic substances ranged with 18.6% and 21.6% in stream flow and reservoir, respectively. Seasonal variation of refractory dissolved organic carbon was similar to that of SUVA.

Development of Constitutive Equation for Soils Under Cyclic Loading Conditions (反復荷重을 받는 흙의 構成關係式 開發)

  • Jang, Byeong-Uk;Song, Chang-Seop
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.34 no.1
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    • pp.41-48
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    • 1992
  • Various soil behaviors usually occurring in the geotechnical problems, such as, cutting and embankments, stability of slope, seepage, consolidations, shearing failures and liquefaction, should be predicted and analyzed in any way. An approach of these predictions may be followed by the development of the constitutive equations as first and subsequently solved by numerical methods. The purpose of this paper is develop the constitutive equation of sands uder monotonic or cyclic loadings. The constitutive equation which is based on elasto-plastic theory, modified anisotropic consolidated stress parameter by Sekiguchi et al and Pender's theory is derived. And the equation is included a new stress parameter, hardening function, Bauschinger's effects and Pender's theory. The model is later evaluated and confirmed the validity by the test data of Ottawa sand, Banwol sand Hongseong sand. The following conclustions may be drawn: 1. The consititutive equation which is based on elasto-plastic theory, modified anisotropic consolidated stress parpameter by Sekiguchi et al and Pender's theory is derived. The equation in included a new stress parameter, hardening function, Bauschinger's effect and Pender's theory. 2. For Ottawa sand, the result of the constitutive equation shows a better agreement than that of Oka et al. The result of axial strain agrees well with the tested data. However, the result of horizontal strain is little bit off for the cyclic loadings or large stress. It is thought that the deviation may be improved by considering Poisson's ratio and precise measurement of shear modulus. 3. Banwol sand is used for the strain and stress tests with different relative densitites and confining pressures. The predeicted result shows a good agreement with the tested data because the required material parameters were directly measurd and determined form this laboratory. 4. For Hongseong sand, the tests under same amplitude of cyclic deviatoric stress shows a similar result with the tested data in absolute strain. It shows the acute shape of turning point because the sine wave of input is used in the test but the serrated wave in prediction.

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Effects of phenolics from Oplismenus undulatifolius in α-MSH-stimulated B16F10 melanoma cells

  • Park, Hye-Jin;Lee, Eun-Ho;Jung, Hee-Young;Kang, In-Kyu;Cho, Young-Je
    • Journal of Applied Biological Chemistry
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    • v.63 no.1
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    • pp.89-93
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    • 2020
  • In this study, the efficacy of melanoma cell B16F10 was investigated using the Korean native plant Oplismenus undulatifolius (OU). First, the cell viability of the extract was more than 90% when treated with 15 ㎍/mL of phenolics from OU. The results showed that melanin biosynthesis and cellular tyrosinase synthesis were inhibited by treatment with α-melanocyte-stimulating hormone-stimulated mouse melanoma cell B16F10 at a concentration of 15 ㎍/mL of phenolics for cell-line efficacy. The expression of tyrosinase, tyrosinase-related protein (TRP)-1, TRP-2, and microphthalmia transcription factor (MITF) protein was confirmed by western blot to investigate the effect of phenolics from OU on melanin biosynthesis. When treated with phenolics from OU 15 ㎍/mL, tyrosinase, TRP-1, TRP-2, and MITF decreased the protein expression level. In particular, tyrosinase, TRP-1, and MITF inhibited the production amount to a level similar to that of the non-treated normal group, indicating that the effect was excellent. Therefore, phenolics from OU acts as an inhibitor of tyrosinase, TRP-1, TRP-2, and its transcription factor MITF, and participates in melanin biosynthesis mechanism. These results suggested the potential for development as a material.

Bi-materials of Al-Mg Alloy Reinforced with/without SiC and Al2O3 Particles; Processing and Mechanical Properties

  • Chang, Si-Young;Cho, Han-Gyoung;Kim, Yang-Do
    • Journal of Powder Materials
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    • v.14 no.6
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    • pp.354-361
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    • 2007
  • The bi-materials with Al-Mg alloy and its composites reinforced with SiC and $Al_2O_3$ particles were prepared by conventional powder metallurgy method. The A1-5 wt%Mg and composite mixtures were compacted under $150{\sim}450\;MPa$, and then the mixtures compacted under 400 MPa were sintered at $773{\sim}1173K$ for 5h. The obtained bi-materials with Al-Mg/SiCp composite showed the higher relative density than those with $Al-Mg/Al_2O_3$ composite after compaction and sintering. Based on the results, the bi-materials compacted under 400 MPa and sintered at 873K for 5h were used for mechanical tests. In the composite side of bi-materials, the SiC particles were densely distributed compared to the $Al_2O_3$ particles. The bi-materials with Al-Mg/SiC composite showed the higher micro-hardness than those with $Al-Mg/Al_2O_3$ composite. The mechanical properties were evaluated by the compressive test. The bi-materials revealed almost the same value of 0.2% proof stress with Al-Mg alloy. Their compressive strength was lower than that of Al-Mg alloy. Moreover, impact absorbed energy of bi-materials was smaller than that of composite. However, the bi-materials with Al-Mg/SiCp composite particularly showed almost similar impact absorbed energy to $Al-Mg/Al_2O_3$ composite. From the observation of microstructure, it was deduced that the bi-materials was preferentially fractured through micro-interface between matrix and composite in the vicinity of macro-interface.

Organic Material Analysis of a Lacquered Wooden Sheath of Long Sword with Ring Pommel Excavated in Imdang Ancient Tomb (경산 임당고분 출토 철제 고리자루칼 칠의 유기물 분석)

  • Park, Jongseo;Cho, Ha-nui;Lee, Jae-sung
    • Journal of Conservation Science
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    • v.34 no.5
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    • pp.369-377
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    • 2018
  • In order to examine the constituents and weathered state of a lacquer specimen, analysis of the organic materials was conducted using py/GC/MS(pyrolysis-gas chromatography-mass spectrometry). The samples were obtained from the lacquered wooden sheath of a long ring-pommel sword excavated in the Imdang No.1 ancient tomb constructed around the Proto-Three Kingdoms period. In direct py/GC/MS, the sample and the dried Asian lacquer showed similar chromatograms, while the characteristic compounds of Asian lacquer such as 1,2-dimethoxy-3-pentadecylbenzene were observed in THM(thermally assisted hydrolysis and methylation)-py/GC/MS. In addition, compounds like dimethyl nonanedioate, which presumably originated from drying oil, were also detected. Furthermore, the detection of oxidized catechols in considerable amount indicated that the degradation of lacquer is estimated to result from the oxidation of urushiol. Therefore, it is suggested that the lacquered wooden sheath was prepared using Asian lacquer and drying oil, and that the lacquer layer was considerably oxidized over the long burial time.