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The Therapeutic Effect of Medical Patches Including Isoegomaketone on the Collagen Antibody-induced Arthritis in Mice (관절염 유발 동물 모델에서 이소에고마케톤 함유 패치의 관절염 치료 효과)

  • ChangHyun Jin;Ye-Ram Kim;Ah-Reum Han
    • Journal of Radiation Industry
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    • v.17 no.4
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    • pp.327-332
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    • 2023
  • This study identified effects of Isoegomaketone for applicable patch on the arthritis in mice. Isoegomaketone (IK) was isolated from Perilla frutescens, which is annual herbal traditional medicinal, aromatic, functional food. IK has various physiological effects such as anti-inflammation, anti-oxidant, and anti-cancer. In the previous study, oral administration of IK to a mouse model of collagen antibody-induced arthritis(CAIA), which is similar to human rheumatoid arthritis(RA), alleviated symptoms. In this study, we attached a patch containing IK to mouse skin to demonstrate whether it had the same efficacy as oral administration in CAIA mouse. As a result of measuring the arthritis score, paw volume, and paw thickness, it was confirmed that arthritis symptoms were alleviated in the group to which the patch containing IK was attached. These results show that IK is effective in alleviating arthritis not only through oral administration but also through patches applied to skin, and that it has potential as a material for future patch development.

Correlation of rebound hammer and ultrasonic pulse velocity methods for instant and additive-enhanced concrete

  • Yudhistira J.U. Mangasi;Nadhifah K. Kirana;Jessica Sjah;Nuraziz Handika;Eric Vincens
    • Structural Monitoring and Maintenance
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    • v.11 no.1
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    • pp.41-55
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    • 2024
  • This study aims to determine the characteristics of concrete as identified by Rebound Hammer and Ultrasonic Pulse Velocity (UPV) tests, focusing particularly on their efficacy in estimating compressive strength of concrete material. The study involved three concrete samples designed to achieve a target strength of 29 MPa, comprising normal concrete, instant concrete, and concrete with additives. These were cast into cube specimens measuring 150×150×150 mm. Compressive strength values were determined through both destructive and non-destructive testing on the cubic specimens. As a result, the non-destructive methods yielded varying outcomes for each correlation approach, influenced by the differing constituent materials in the tested concretes. However, normal concrete consistently showed the most reliable correlation, followed by concrete with additives, and lastly, instant concrete. The study found that combining Rebound Hammer and UPV tests enhances the prediction accuracy of compressive strength of concrete. This synergy was quantified through multivariate regression, considering UPV, rebound number, and actual compressive strength. The findings also suggest a more significant influence of the Rebound Hammer measurements on predicting compressive strength for BN and BA, whereas UPV and RN had a similar impact on predicting BI compressive strength.

Development of Real-Time Active Type Seals (실시간 능동형 타입 격납장치 개발)

  • Jung-ki Shin;Heekyun Baek;Yongju Lee
    • Journal of Radiation Industry
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    • v.18 no.1
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    • pp.9-14
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    • 2024
  • In order to thoroughly verify the denuclearization of the Korean Peninsula, it is urgent to develop technology capabilities to monitor, detect, collect, analyze, interpret, and evaluate nuclear activities using nuclear materials and secure nuclear transparency. The IAEA is actively using seal technology to maximize the efficiency of safety measures, and currently uses metal cap, paper, COBRA, and EOSS as seal devices. Unlike facilities that comply with safety measures requirements, such as domestic nuclear facilities, facilities subject to denuclearization are likely to have various risk environments that make it difficult to apply safety measures, and there is a high possibility that continuity of knowledge (COK) such as damage, malfunction, and power loss will not be maintained. This study aims to develop a real-time active seal device that can be applied in such special situations to enable immediate response in the event of a similar situation. To this end, the main functions of the real-time seal device were derived and applied, and a commercialized seal device and operation software. The real-time seal technology developed through this study can be applied to all nuclear facilities in South Korea, especially used as storage equipment for dry cask storage facilities of heavy water reactor's after fuel, and it is believed that unnecessary radiation exposure by inspectors can be minimized.

Analytical Study on the Seismic Capacity for Existing Masonry Building in Korea (국내 기존 조적조 건축물의 내진성능에 관한 해석적 연구)

  • Heo, Jae-Sang;Lee, Sang-Ho
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.13 no.6 s.58
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    • pp.75-87
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    • 2009
  • In this study, FEM analysis has been performed based on the results from domestic experimental researches regarding to material and member characteristics of masonry. After validation of reliability for the used FEM analysis method, this study is progressed the evaluation of seismic capacity for existing prototype masonry building in Korea. According to the evaluation for the prototype masonry building, the horizontal shear force and the average shear stress are similar to those of previous studies.

A Study on Cultural Appropriation of Fashion Design in the Era of Globalization - Focusing on Traditional Culture - (세계화 시대의 패션디자인 문화적 전유에 관한 연구 - 전통문화를 중심으로 -)

  • Yu HE Chen;Chahyun Kim
    • Journal of Fashion Business
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    • v.28 no.3
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    • pp.69-89
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    • 2024
  • In the era of globalization, cultural appropriation, stemming from the interaction and clash of diverse cultures, remains inadequately defined, leading to controversy in many designs. This study aims to provide a theoretical basis for understanding cultural appropriation by comparing similar concepts and examining specific cases. It proposes methods for the rational use of traditional cultures in apparel to minimize controversy. Firstly, the study investigates the concept of cultural appropriation by exploring differences among related terms. Secondly, it examines instances of cultural appropriation in fashion through form, color, pattern, and material, drawing from papers and Google searches over the past decade. Thirdly, it categorizes representative cases by domestic and foreign fashion brands, analyzing the underlying reasons. The goal is to establish a theoretical foundation for developing culturally sensitive clothing products. Based on the findings, several measures are proposed: understanding and respecting cultural backgrounds through in-depth research on the history and significance of elements; collaborating with cultural groups and consulting experts for feedback; explaining the source of design inspiration to help consumers understand the cultural elements' meanings; avoiding the reinforcement of stereotypes and respecting cultural diversity and complexity; respecting intellectual property and ensuring moral and legal appropriateness; and learning from case studies of other designers' and brands' successes and failures.

Analyzing quality characteristics of texturized vegetable protein using defatted soy flour with rice flour and rice starch

  • Chan Soon Park;Mi Sook Seo;Sun Young Jung;Seul Lee;Boram Park;Shin Young Park;Yong Suk Kim
    • Food Science and Preservation
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    • v.31 no.4
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    • pp.518-526
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    • 2024
  • This study analyzed the quality of texturized vegetable protein (TVP) made from defatted soy flour combined with flour or starch from rice sources. The base raw material formulation consisted of 50% soybean protein, 30% gluten, and 20% rice flour and rice starch. A cooling die-equipped extruder was used with a barrel temperature of 190℃ and screw rotation speed of 250 rpm. The hardness and cutting strength of the extruded TVP were found to be higher for white rice than for glutinous rice and higher for flour than for starch. Gumminess and chewiness were similar across rice types, but higher for flour than for starch. White rice TVP had a lower water absorption capacity than glutinous rice TVP. Turbidity was lowest for white rice flour and highest for corn starch. Using rice flour instead of starch in TVP production can simplify processing and contribute to promoting the consumption of rice.

Structural, physical and electrical properties of SiO2 thin films formed by atmospheric-pressure plasma technology

  • Kyoung-Bo Kim;Moojin Kim
    • Journal of Ceramic Processing Research
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    • v.23 no.4
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    • pp.535-540
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    • 2022
  • Atmospheric pressure plasma (APP) systems operate at atmospheric pressure and low temperatures, eliminating the need forvacuum systems such as vacuum chambers and pumps. In this paper, we studied that silicon dioxide thin films were formedat room temperature (25 oC) and 400 oC by APP processes on silicon wafers. A mixture of hexamethyldisilazane, oxygen,helium, and argon was supplied to the plasma apparatus to form the SiO2 layer. It was observed that a heat insulating layerhaving a thickness of about 22 nm at 25 oC and about 75 nm at 400 oC was formed. Although the surface was clean in samplestreated at 400 oC, small grains were observed in samples processed at room temperature. However, no void or defect in allsamples is observed inside the thin film from the surface. The physical property of the SiO2 thin film carried out by measuringrefractive index and density. The experimental refractive index of silicon dioxide grown by applying heat can be fitted to theSellmeier equation. Also, the film density of the sample at 400 oC using a XRR was observed to be 2.25 g/cm3, similar to thatof the glass, but that of the sample treated at room temp. was very low at 1.68 g/cm3. We also investigated the voltagedependentcurrent change in the oxide material. The SiO2 layer coated at room temperature showed a breakdown electricalfield of 2.5 MV/cm, while oxides deposited at 400 oC showed a characteristic of 9.9 MV/cm.

Exploring Fundamental Concepts of Nature Sports

  • Hyeong KANG;Won Jae SEO
    • Journal of Sport and Applied Science
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    • v.8 no.3
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    • pp.7-11
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    • 2024
  • Purpose: This study sought to explore concepts and features of nature sports. In specific, this study reviewed literature discussing historical background of nature sport and its relationship with related fields including conservation, tourism, and education. Research design, data, and methodology: This study employed an integrated literature review approach. For this, the study collected prior studies and reports via google scholar. Further the collected studies were analyzed and major issues regarding concepts and features of nature sport were presented. Results: For results, various definitions of nature sports and similar activities were presented. The study found that nature sports labelled action sports, adventure sports, alternative sports, Californian sports, extreme sports, gravity sports, lifestyle sports, nature challenge activities, new sports, outdoor sports, panic sports, risk sports or whiz sports, among others. Nature sport involve interacting with a natural or material feature, rather than with other human beings. Furthermore, this study discovered features of nature sport, including nature based activities, sustainable activities, adventure and risk activities, hedonistic and non-competitive activities, and autonomous and individualistic activities. Conclusions: Nature sport has its own distinctive features compared with traditional sport, yet it shows similarities with constructive sport in terms of perceived benefits and so forth. Further implications were discussed.

Nonlinear primary resonance of multilayer FG shallow shell with an FG porous core reinforced by oblique stiffeners

  • Kamran Foroutan;Liming Dai
    • Structural Engineering and Mechanics
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    • v.91 no.5
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    • pp.503-516
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    • 2024
  • The present research examines the primary resonance (PR) behaviors of oblique stiffened multilayer functionally graded (OSMFG) shallow shells featuring an FG porous (FGP) core under an external excitation. The research considers two distinct types of FGP cores: one characterized by uniform porosity distribution (UPD) and the other by non-uniform porosity distribution (NPD) along the thickness direction. Furthermore, the study explores two types of shallow shells: one with external oblique stiffeners and one with internal oblique stiffeners, which might have angles that are similar or different from each other. Using the stress function alongside the first-order shear deformation theory (FSDT), the research establishes a nonlinear model for OSMFG shallow shells. The strain-displacement relationships are obtained utilizing FSDT and von-Kármán's geometric assumptions. The Galerkin approach is utilized to discretize the nonlinear governing equations, allowing for the analysis of stiffeners at varied angles. To validate the obtained results, a comparison is made not only with the findings of previous research but also with the response of PR obtained theoretically with the method of multiple scales, using the P-T method. Renowned for its superior accuracy and reliability, the P-T method is deemed an apt selection within this framework. Additionally, the study investigates how differences in material characteristics and stiffener angles affect the system's PR behaviors. The results of this study can be used as standards by engineers and researchers working in this area, and they can offer important information for the design and evaluation of the shell systems under consideration.

Can discolored dental composites be bleached in depth?

  • Luca Giachetti;Daniele Scaminaci Russo;Michele Nieri;Francesca Cinelli
    • Restorative Dentistry and Endodontics
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    • v.49 no.3
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    • pp.23.1-23.10
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    • 2024
  • Objectives: Previous in vitro studies determined the whitening effects of bleaching products on stained resin composite surfaces. This in vitro study aimed to verify the effectiveness of a whitening system on composite resin previously subjected to pigmentation, specifically examining the depth of whitening effectiveness within the material structure. Materials and Methods: A commercially available nano-filled composite resin was used. Specimens were stained using a coffee-based solution and a 10% carbamide peroxide-based gel was employed as the whitening agent. The pigment's penetration and the effect of the bleaching gel were evaluated by measuring color (CieLab values) from the outer edge to the inner part of the specimens. Color measurements were taken at 14 points, starting from 0.1 mm from the external perimeter up to 3.0 mm. Results: Analysis of variance tests showed a statistically significant difference between the Control Group (CG), Pigmentation Group, and Whitening Group. The whitening agent was effective up to 1.5 mm in depth, with Whiteness index (W) values not statistically different from those of CG up to 0.5 mm in depth. Conclusions: Whitening agents on nano-filled resin composite previously pigmented appear effective in restoring the W to values similar to the original, particularly in the superficial layers of the sample.