• The Korean Journal of Applied Statistics
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• v.21 no.1
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• pp.19-33
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• 2008

Linear regression method, proposed by Haseman and Elston(1972), for detecting linkage to a quantitative trait of sib pairs is a linkage testing method for a single locus and a single trait. However, multivariate methods for detecting linkage are needed, when information from each of several traits that are affected by the same major gene are available on each individual. Amos et al. (1990) extended the regression method of Haseman and Elston(1972) to incorporate observations of two or more traits by estimating the principal component linear function that results in the strongest correlation between the squared pair differences in the trait measurements and identity by descent at a marker locus. But, it is impossible to control the probability of type I errors with this method at present, since the exact distribution of the statistic that they use is yet unknown. In this paper, we propose a multivariate nonparametric trend test for detecting linkage to multiple traits. We compared with a simulation study the efficiencies of multivariate nonparametric trend test with those of the method developed by Amos et al. (1990) for quantitative traits data. For multivariate nonparametric trend test, the results of the simulation study reveal that the Type I error rates are close to the predetermined significance levels, and have in general high powers.

• The Journal of Korean Medicine
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• v.29 no.1
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• pp.117-133
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• 2008

Objectives : Since ancient times, Koreans have applied medicinal spabaths for treatment of various diseases. The objective of this study was to investigate the effect of strontium, one of the common ingredients of such baths, experimentally on acute skin barrier damage. Materials and Methods : Male hairless mice, average weight 20g, were divided into six groups. Each group consisted of five mice. The first was the normal, non-treated group. The second was the control group with acute skin barrier damage intentionally induced by TS. The third was the Ba-Sr1 group bathed in 1mg/L strontium chloride before and after inducing acute skin barrier damage by TS. The fourth was the Ba-Sr7 group bathed in 7mg/L strontium chloride before and after inducing acute skin barrier damage by TS. The fifth was the Sr1 group bathed in 1mg/L of strontium chloride only after intentionally inducing acute skin barrier damage by TS. The sixth was the Sr7 group bathed in 7mg/L of strontium chloride only after intentionally inducing acute skin barrier damage by TS. External changes of skin, skin erythema level, transepidermal water loss level, and GOT and GPT level of each group were checked immediately before and after TS, 3 hrs, 5 hrs and 24 hrs after inducing acute skin barrier damage. Then, tissue samples were made and examined for damage to epithelial cells, stratum corneum, change of mucous polysaccharide in dermis and amount of mast cells. Statistical analysis was performed by one way-ANOVA, Scheffe and Duncan for a post hoc test and pairwise comparison for comparing for difference between each time. Statistical significance was achieved if the probability was less than 5% (p<0.05) Results : 1. From skin erythema and TEWL level indicating the function of the skin barrier, we can know that it is helpful to the skin barrier to bathe in a water solution including a low concentration of strontium. 2. In the control group with acute skin barrier damage induced by TS, skin barrier damage persisted until 3-5 hrs and recovered after 5-24 hrs. Differently from the control group, in the case of taking a bath in a water solution including strontium, skin barrier damage recovered after only 3-5 hrs. Therefore, the bath with a water solution including strontium can promote recovery of the skin barrier. 3. Bathing in water solution including a higher concentration of strontium was more beneficial to recovery of skin barrier damage. 4. There was no influence on serum GOT and GPT from bathing in a water solution including strontium. Conclusions : The strontium was effective for recovery and mitigation of acute skin barrier damage induced by tape stripping. I suggest that strontium (Sr) can be used as an external treatment medicine, addedinto bath water to treat acute skin barrier damage.

• Journal of Korean Society of Environmental Engineers
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• v.39 no.10
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• pp.568-574
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• 2017

The purpose of this study was to optimize experimental conditions (time ($X_1$) (ranging of 26.36 - 93.64 min), concentration of sulfuric acid ($X_2$) (ranging of 0-2.5%) and temperature ($X_3$) (ranging of $136.4-203.6^{\circ}C$) for an organosolv pretreatment process to extract lignin from waste wood. The resulting quadratic model equation using RSM (response surface methodology) represented y (lignin yield) = $-79.89+0.91X_1+9.8X_2-2.54{\times}10^{-3}X_1{^2}-2.11X_2{^2}$. The $R^2$ (coefficient of determination) value of 0.8531 for a model indicates this model has statistically significant predictors at the 10% levels. The predictive results optimized by quadratic model produced a lignin yield of 12.46 g/100 g of dry wood under conditions of $178.2^{\circ}C$ and 2.32% $H_2SO_4$. The lignin yield was more affected by the acid catalyst concentrations than the reaction temperature, but the reaction time was not an influential factor for improving lignin extraction from waste wood in this organosolv pretreatment. According to ANOVA (analysis of variance), the significance probability (p-value) of model was smaller than 0.001 and simulation of obtained model equations showed a good reproducibility based on actual organosolv tests under optimal conditions.

• Industry Promotion Research
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• v.2 no.1
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• pp.69-75
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• 2017

In this study, 62 questionnaires were surveyed from November 3 to November 25, 2016 for workers who received more than one skill improvement training at Korea Polytechnic University. Factor analysis was done by removing 11 items out of 27 items and using the final 16 items, five factors were derived and the validity was confirmed with significance probability p = .000. Durbin-Watson values were 1.787 and 1.780, respectively. The results of this study were as follows: First, the effects of skill enhancement training on job attitude of Korea Polytechnic University were found as follows. First, the effects on job satisfaction were consistency of contents (p <.05, ${\beta}=.434$) (P <.05, p = .328), and the sense of belonging was significant (p <.05, p = .338). Second, the correlation between the skill improvement training and the turnover attitude shows that the efficiency of method - job satisfaction (.311), efficiency of method - clarity of purpose (.350), efficiency of method - suitability of content (.771) - content fit (.467), job satisfaction - content fit (.191), but the sense of belonging was not correlated. Third, the results of the difference in perception of turnover attitude according to years of service of technical improvement training at Korea Polytechnic University did not have a statistically significant effect. In this study, it is meaningful to investigate the effect of the skill improvement training on the attitude of turnover and its effectiveness.

• Journal of Korean society of Dental Hygiene
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• v.9 no.4
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• pp.715-725
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• 2009

Objectives : The purpose of this study was to analyze the influence which the professional dental hygiene education has on the knowledge and behavioral change for oral health to the students in the departments of dental hygiene. Methods : 771 students in the first grade and 646 students in the third grade who were attending the departments of dental hygiene from 12 colleges in Korea were surveyed. The self-administered questionnaires were distributed to the students in the colleges during May and asked them to answer the questions and then recovered them on the spot. The collected questionnaires were analyzed by using a SPSS/PC program and the difference of significance depending on the group of the students was tested by Chi-square test or Fisher's exact probability test. Results : In the number of eating snacks by the students during one day, 2-3 times was the highest, irrespectively of the grade. The rate of the students brushing their teeth after snack was higher in the third-grade students(34.8%) than in the first-grade students(20.8%). As the path of acquiring oral health knowledge, all of the first-grade and third-grade students replied that their school classes had impacted them the most. The rate of toothache experience was a higher tendency in third-grade students compared to the first-grade students(p=0.116). The rate of gingival bleeding experience was lower in the third-grade students than in the first-grade students. The rate of oral prophylaxis experience was higher in the third-grade students than in the first-grade students. In the smoking rate, there was lower in the third-grade students than in the first-grade students. The rate of acknowledging smoking hazard to the periodontal health was higher in the third-grade students than in the first-grade students. Conclusions : This study revealed that the third-grade students of dental hygiene departments who were majoring in dental hygiene had a higher perception of oral health than the first-grade students whose the dental hygiene education period was short.

• The Journal of Korean Academy of Prosthodontics
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• v.43 no.4
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• pp.438-452
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• 2005

Statement of problem: The use of Ceromer is increasing in dentistry. But, the research of Ceromer has not been conducted much. Purpose : This study was to evaluate the marginal fidelity and internal adaptation according to marginal position. Materials and Methods: In this study 60 resin crowns were fabricated. The measurements of the marginal fidelity were carried out using stereomicroscope $SZ-40^{(R)}$ (Olympus, Japan) and the measurements of fracture strength were done using Instron $8871^{(R)}$ (Instron Co., U.S.A.) at a cross head speed of 1mm/min. All of the measurements were statistically analyzed by ANOVA test, multiple range test and Weibull analysis. Statistical significance was set in advance at the probability level of less than 0.05. All of the measurements were analyzed with Window $SPSS^{(R)}$ Version 10.0 soft ware for the personal computer. Results : 1. There were no statistical differences of the marginal fidelity between $Targis^{(R)}$ and $Tescera^{(R)}$, but difference between these two and $BelleGlass^{(R)}$ according to materials. 2. There were no statistical differences of the marginal fidelity between no fiber group and fiber group. There were no interactions between each maerial and with/without fiber group in the marginal fidelity 3. There were statistical differences of the fracture strength between $Tescera^{(R)}$ and $BelleGlass^{(R)}$ but no statistical differences of the fracture strength between $Targis^{(R)}$ and $Tescera^{(R)}$, $Targis^{(R)}$ and $BelleGlass^{(R)}$ according to materials. 4 There were statistical differences of the fracture strength between no fiber group and fiber group. There were no interactions between each material and with/without fiber group in the fracture strength. 5. When comparing the fracture surface, no fiber group showed the resin which were fractured at the labial surface and separated from the adhesion surface. In fiber group, the fractures took a place in resin compartments. Conclusion. The marginal fidelity and the fracture strength were clinically acceptable. From these results, $Targis^{(R)}$ and $Tescera^{(R)}$ were superior than $BelleGlass^{(R)}$ in the marginal fidelity But, when applying these resin crowns in clinic, more careful consideration is needed and further study is recommended.

• The Journal of the Korea Contents Association
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• v.20 no.2
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• pp.534-546
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• 2020

The purpose of this study is to prove the positive effect of mind and body healing through the modified meditation method of Southern Buddhism as a systematic practice to concentrate or empty consciousness of the Buddhist temple in Dhammakaya, Thailand. To investigate the effects of the program on the participants, the experimental measurement tools in this study include the Immeasurable scale, spirituality scale, simple mental test scale, and blood pressure scale, pulse meter, thermometer, and recorder. When the measured values were compared with the corresponding t-test, there were some differences before and after the measurements based on the significance probability p <0.05. As a result, there was a significant correlation between spiritual support scale and the Immeasurable scale. In addition, the results of analyzing the data through interviews showed that the body and physiologically effective concentration was well after the meditation experience, and the intention to actively utilize this meditation method was confirmed. In this study, it was confirmed that there was a positive effect of the Samata practice method of Concentration meditation(CM), and thus the theoretical and experimental effects of intensive meditation were presented. I hope that these studies will accumulate and follow-up studies will be conducted through intensive meditation as a healing effect.

• Journal of Bio-Environment Control
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• v.1 no.1
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• pp.1-13
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• 1992

This study was attemped to provide some fundamental data for the safety structural design of biological production facility. Wind speed and snow depth according to recurrence intervals for design load estimation were calculated by frequency analysis using the weather data of 60 stations in Korea. The following results were obtained : 1. Type-I extremal distribution was selected for the probability density function of yearly maximum wind speed and snow depth and result of Chi-square goodness of fit showed highly significance at most regions. 2. Design frequency factors for given number of samples and recurrence intervals were calculated, and also design wind speed and snow depth as shown in Table 5-Table 6 and Fig.3-Fig.4 were derived. 3. About 46.4% of the winds having maximum wind speed at every station was analyzed to be same direction, and the consideration of this fact may improve the structural safety. 4. Considering wind speed and snow depth, protected cultivation is very difficult in Ullungdo and the Youngdong districts, and strong structural design is needed in the Chungnam and Junbuk west seaside against snow depth and the west-south seaside against wind speed in Korea.

• Korean Security Journal
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• no.37
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• pp.7-28
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• 2013

Based on the status of which the research is not active and the analysis is not progressed, the purpose of this study life up pride, value and professional ethic of private security guard. Also, through this research, it offers the effect on professional ethic, organizational trust and job satisfaction. The data collection and survey are taken by the private security business members who work staff member or manager. They are surveyed with convenience sampling that among 500 data, 46 data which are thought to be answered insincerely or lack are excluded, so the total of 454 answered data are included in the final analysis. After coding and input process, the data is analyzed by factor analysis, reliability analysis, correlation analysis and multiple regression analysis using window SPSS 19.0 version. Significance level is 0.05. The conclusion that has been made based on the statistical analysis results are the followings. Professional ethic has a positive impact on organizational trust, job satisfaction. The educational training of the company is connected job satisfaction resultantly. Also the professional ethics education will improve the ability of the individual. Finally, the professional ethics raises a job satisfaction. Also, Organizational trust has a positive impact on job satisfaction. This the while to agree with a research result about the other type of business worker who is researched. In order raising the job satisfaction, the effort for raising a organizational trust is necessary.

• Herbal Formula Science
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• v.28 no.2
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• pp.157-167
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• 2020

Objectives : The purpose of this clinical study was to investigate the efficacy and safety of Hwangryunhaedok-tang on the gastritis treatment. Methods : A total of 20 subjects who visited Pusan National University Hospital from April 2nd, 2019 to September 2nd, 2019 were included. In this study, we evaluated the individual symptoms through questionnaires, laboratory test, BIA (Bioelectrical Impedance Analysis), and adverse reaction according to medication. Statistical analysis was performed with paired t-test and Wilcoxon Signed Rank test. Statistical significance was achieved if the probability was less than 5% (p < 0.05). Results : After medications, the total score of individual symptoms, primary outcome, was significantly decreased. In particular, individual symptoms such as upper abdominal pain, bloating, heartburn and trim showed significant improvement. However, no statistically significant differences were found in nausea/vomiting and anorexia. In additions, the laboratory test showed a statistically significant decrease in total cholesterol, but no statistically significant differences in results of BIA. In the safety evaluation, adverse reactions were not reported. Conclusions : Considering this results, we have confirmed the possibility of Hwangryunhaedok-tang to the gastritis treatment.