• Title/Summary/Keyword: shin-huh

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Radiation Therapy of Primary Carcinoma of the Vagina (원발성 질암의 방사선치료)

  • Huh, Seung-Jae;Shin, Kyung-Hwan;Ahn, Yong-Chan;Ha, Sung-Whan;Park, Charn-Il
    • Radiation Oncology Journal
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    • v.13 no.1
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    • pp.63-67
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    • 1995
  • A retrospective study was carried out of 20 patients with histologically proven invasive carcinoma of the vagina from 1979 to 1993; 17 cases with curative primary radiotherapy and three cases with postoperative radiotherapy. The five and ten year overall survival rates were $79\%$ and $53\%$, respectively. Survival was strongly correlated with stage. Five year survival rates of stage I, stage II, and stage III, IV were $100\%$, $78\%$, and $0\%$, respectively. Eight patients experienced recurrences: five within the irradiated volume, two distant metastasis, and one combined both local and distant metastasis. There was no significant late complication. From these data, radiation is effective in the management of the vaginal cancer patients and optimum treatment modality and total dose recommendation are made.

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The Holding Characteristics of the Glass Filter Separators of Molten Salt Electrolyte for Thermal Batteries (열전지용 용융염 전해질의 유리필터분리판의 담지특성)

  • Cho, Kwang-Youn;Riu, Doh-Hyung;Huh, Seung-Hun;Shin, Dong-Geun;Kim, Hyoun-Ee;Cheong, Hae-Won;Cho, Sung-Baek
    • Journal of the Korean Ceramic Society
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    • v.45 no.8
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    • pp.464-471
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    • 2008
  • The electrolyte separator for thermal battery should be easily handled and loaded a large amount of the molten salt. Ceramic fibers, especially fibrous commercial glass filters were used as an electrolyte separator and the lithium based molten salts were infiltrated into the ceramic filters. The pore structures of the ceramic filter and the melting properties of the lithium salts affected to the electrolyte loading and leakage. During the infiltration, ions of $Li^+$ and $F^-$ in the molten salts were reacted with the glass fiber and caused to be weaken the fiber strength.

Genomewide Profiling of Rapamycin Sensitivity in Saccharomyces cerevisiae on Synthetic Medium

  • Chang, Yeon-Ji;Shin, Chun-Shik;Han, Dong-Hun;Kim, Ji-Yun;Kim, Kang-In;Kwon, Yong-Min;Huh, Won-Ki
    • Genomics & Informatics
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    • v.8 no.4
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    • pp.177-184
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    • 2010
  • The target of rapamycin (TOR) signaling pathway is a conserved pathway that regulates eukaryotic cell growth in response to environmental cues. Chemical genomic approaches that profile rapamycin sensitivity of yeast deletion strains have given insights into the function of TOR signaling pathway. In the present study, we analyzed the rapamycin sensitivity of yeast deletion library strains on synthetic medium. As a result, we identified 130 strains that are hypersensitive or resistant to rapamycin compared with wild-type cells. Among them, 36 genes are newly identified to be related to rapamycin sensitivity. Moreover, we found 16 strains that show alteration in rapamycin sensitivity between complex and synthetic media. We suggest that these genes may be involved in part of TOR signaling activities that is differentially regulated by media composition.

The Synthesis and Physical Properties of Water Soluble Metal Working Oil by Soybean Oil Ester (대두유 에스테르에 의한 수용성 윤활유의 물성 연구)

  • Huh, Do Sung;Shin, Su Bum;Kim, Min Suk;Kim, Hye Sook
    • Journal of the Korean Chemical Society
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    • v.44 no.3
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    • pp.237-242
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    • 2000
  • We have synthesized ester compounds from the soybean oil and some Polymer alcohol compounds and studied the physical properties of the synthesized esters. We have performed this experiment for the purpose of testing the physical properties by soybean oil ester compounds as a water-soluble metal working lubricant.In addition, we have studied siy, surface tension, viscosity for the synthesized ester compounds in aqueous solution state varying the mixing ratio of water.

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Preparation and Characterization of Rosiglitazone-loaded PLGA Nanoparticles (Rosiglitazone약물을 함유한 PLGA 나노입자 제조 및 분석)

  • Shin, Ko-Eun;Huh, Kang-Moo;Lee, Yong-Kyu
    • KSBB Journal
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    • v.23 no.5
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    • pp.408-412
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    • 2008
  • The rosiglitazone loaded poly (lactide-co-glycolide) (PLGA) nanoparticles (NPs) were prepared by the emulsion-evaporation method and optimized for particle size and entrapment efficiency. The optimized particles were 140-180 nm in size with narrow size distribution and 80% entrapment efficiency at 1% w/w initial drug loading when prepared with 1-3% w/v of PVA as a surfactant. These particulate carriers exhibited controlled in vitro release of rosiglitazone for 36 hrs at a nearly constant rate after 4 hrs release. In conclusion, these results indicate that PLGA NPs have greater potential for oral delivery of rosiglitazone.

Three Case Reports about Improving Vascular Dementia and Secondary Dementia (혈관성 치매와 속발성 치매 치험 및 호전 3례)

  • Yun Kyoung-Sun;Lee Ji-Hun;Kim Jae-Woo;Jeong Sung-Hyun;Shin Gil-Cho;Lee Won-Chul
    • The Journal of Internal Korean Medicine
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    • v.24 no.4_2
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    • pp.1103-1111
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    • 2003
  • Dementia is classified into Alzheimer's disease, vascular dementia and secondary dementia by its causes. Alzheimer's disease is hard to expect cognitive improvement, whereas vascular dementia and secondary dementia are reversible by medical treatments Dementia can be categorized as Chi-Mae(痴?), Geon-Mang(健忘), Huh-Ro(虛勞), Guang(狂), in the oriental medicine and treated by 'purgation therapy' when it is classified into excessive syndrome. We observed some significant improvements in the cognitive function from three patients diagnosed vascular dementia and secondary dementia by herbal medications of $\ulcorner$Dong-Eui-Su-Sheh-Bo-Won(東醫壽世保元)$\lrcorner$. We report the process of the treatment.

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Ultrastructure of virus particles in the liver of piglets infected with porcine enterovirus serotype 3 (Enterovirus 감염 돼지의 간에서 virus의 형태학적 관찰)

  • Shin, Tae-kyun;Lee, Cha-soo;Huh, Min-do
    • Korean Journal of Veterinary Research
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    • v.32 no.2
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    • pp.207-210
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    • 1992
  • Oral infection of colostrum-deprived, neonatal piglets with porcine enterovirus serotype 3 can result in hepatic lesions with a short incubation period. In the thin section of the affected liver, crystalline arrays of virus particles characteristic of picornavirus were identified in the sinusoid endothelial cells and Kupffer cells. There were also cytoplasmic aggregates of electron- dense, virus-like particles in the hepatocytes. These findings suggest that porcine enterovirus serotype 3 has hepatotropism as well as neurotropism.

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Protective Effect of Urokinase on Reperfusion Function in Isolated Perfused Rat Heart, and Anti-platelet Aggregation Effect Invitro and Exvivo (Urokinase의 적출심장의 심근허혈에 대한 보호작용과 invitro 및 exvivo항혈전작용 실험)

  • Kwon, Kwangil;Shin, Hongseup;Yoon, Jongok;Kim, Boshin;Min, Jiha;Lee, Byungho;Huh, Inhoe
    • Korean Journal of Clinical Pharmacy
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    • v.2 no.1
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    • pp.1-9
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    • 1992
  • Protective effect of urokinase on reperfusion were studied followed by global ischemia in the isolated perfused rat heart. Separately, anti-platelet aggregation effect of urokinase also investigated. Urokinase exhibited positive effect for the protection of rat heart function by increasing the LV dp/dt, coronary flow(CF) and the Tate pressure product(RPP), and by decreasing the LVEDP on reperfusion. Urokinase also decreased arrhythmia by $74.7\%(P<0.05) induced by global ischemia in the rat heart. In the platelet aggregation study, urokinase did not show the inhibitory effect of ADP or collagen induced platelet aggregation inviuo and exvivo.

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A Study on the Reduction of Onboard Transformer Inrush Current of Electric Railway (전기철도 차량 내 변압기의 여자돌입전류 저감에 관한 연구)

  • Huh, Jae-Sun;Kang, Byoung-Wook;Shin, Hee-Sang;Kim, Jae-Chul
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.12
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    • pp.2125-2130
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    • 2010
  • The neutral section on electric railway system is significant sector in order to prevent short circuit of two electric powers. However, while electric trains pass the neutral section, those speed is decreased and the accident of AC electric traction system and the electric train would be occurred. So the countermeasures are urgently needed. The automatic power switching technology system that is current being research and development is system to improve these problems. Because main object of this system is power change using static switch in the neutral section, it's expected to cause a variety of transients. Especially, onboard transformer inrush current for electric railway train can be occurred more than rated current according to switching time. Therefore, the analysis and improvement are needed to ensure the stability of this system. In this paper, we analyze the operating characteristics of the automatic power switching technology system. Especially, it reviews inrush current according to the closing phase angle. And we propose control plan of inrush current considering the case that voltage is maintained due to counter electromotive force and regenerative braking operation of electric railway train. Finally, the proposed control scheme was reviewed using the transient analysis program.

Immediate loading on mandibular edentulous patient with SFI Bar$^{(R)}$ overdenture

  • Kim, Ha-Young;Kim, Jin-Young-Ryan;Qadeer, Sarah;Jeong, Chang-Mo;Shin, Sang-Wan;Huh, Jung-Bo
    • The Journal of Advanced Prosthodontics
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    • v.3 no.1
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    • pp.47-50
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    • 2011
  • Despite the greater retention and low maintenance of bar attachment system, the longer clinical time and increased number of visits were the assignments to overcome in bar attachment system. This case report describes SFI-Bar$^{(R)}$ (Cendres et Me$\'{e}$taux, Biel/Bienne, Switzerland) to be solve those problems. A 65-year-old female, who had severely absorbed mandible, hoped to wear a stable mandibular denture without pain. As soon as two implants were placed on mandible, a tube bar was connected to two adaptors connected to each implant. The length of the tube bar was adjusted considering inter implant distance, and reconnected to the adaptors. Finally a female part was seated beneath the denture. This case report showed that a satisfactory clinical result was achieved by delivering bar overdenture immediately after implant placement without laboratory procedure.