• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.739-742
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• 2016

Risks with GSTM1 genotypes and potential roles of smoking in the susceptibility to oral squamous cell carcinoma (OSCC) were studied in Northeastern Thailand. Study subjects were 79 histologically-confirmed OSCC cases (31 men, 48 women) and 79 age- and sex-matched healthy controls ranging in age from 25 to 84 years. GSTM1 genotyping was achieved by two independent PCR assays. The GSTM1 null allele and the homozygous genotype did not increase risk of OSCC vs the wild type allele and the remaining genotypes. When the focus was on the smoking habit, male subjects who smoked ${\geq}10$ or ${\geq}35$ years were at significantly increased risk for OSCC with adjusted ORs of 4.88 [95%CI, 1.41-16.87, p=0.012] or 4.94 [95%CI, 1.62-15.12, p=0.005], respectively. A higher risk for OSCC was found for smoking amount; those who smoked >5 or >10 pack-years were at a higher risk with adjusted OR of 4.46 [95%CI; 1.45-13.74, p=0.009] or 3.89 [95%CI; 1.34-11.28, p=0.012], respectively. There are certain smoking patterns that give greater risks and thus both smoking duration and pack-years should be taken into consideration in tobacco related cancer prevention.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7583-7586
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• 2013

Background: Suppressor of cytokine signaling (SOCS)-1 acts as a key regulator of many cytokine signaling pathways and its abnormal expression has been identified in several human malignancies, suggesting potential roles in carcinogenesis. The aim of this study was to investigate any association between the functional SOCS-1 -1478CA>del polymorphism and colorectal cancer (CC) as well as age at onset in a Turkish clinical sample. Materials and Methods: A total of 122 subjects were enrolled in this case-control study (70 CC cases and 52 controls). The SOCS-1 -1478CA>del polymorphism was genotyped using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Results: The odds ratio of the del allele for CC relative to the CA allele was not significantly different between the groups (OR=0.71, 95% CI=0.41-1.22, p=0.27). This result did not change after adjustment for age and sex on multivariable regression analysis (OR=0.84, 95% CI=0.59-1.34, p=0.53). When the SOCS-1 -1478CA>del polymorphism was analyzed among CC patients in relation to the age at disease onset, we found no significant differences between subjects with the del/del, CA/del, and CA/CA genotypes. Conclusions: The results of our study did not point towards a major role of the SOCS-1 -1478CA>del polymorphism in the pathogenesis of CC in Turkish subjects.

• The Journal of the Korea Contents Association
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• v.10 no.6
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• pp.275-285
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• 2010

As we enter an era of emotional and endlessly competitive society, there has been a lot of changes happening to the styles and images of men, traditionally associated with strength and power. Today, the media is giving information on today's trendy men's styles and images to meet the growing demand by consumers, and giving appropriate gains in the process to all - both information providers and consumers. Generally speaking, the cover of a magazine represents the concept and image of the magazine. The cover model is closely tied with the symbolic image of the magazine, the current times, and what the general public wants. Therefore, research on the cover models of a lifestyle magazine has significance in that the current style trends will be able to be understood directly. The present research investigated the sexual images of men's magazine cover models. In carrying out the research, the sexual images were classified into the following: homosexual, cross sexual, metro sexual, and uber sexual. The research findings showed that uber sexual is the dominant sexual image in men's magazines in Korea, followed by metro sexual. In conclusion, the findings suggest an expansion of the traditional image of men, happening with the changes in traditional sex roles.

• Journal of the Korean Home Economics Association
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• v.18 no.2
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• pp.63-68
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• 1980

In a rapidly changing Korean society, the role of home economics in ideological education and practical professionalism is faced to be reset. In this article the author reviews home economics and career opportunities. the following issues were discussed in detail : 1. Home Economics and Occupation ; a) As professionals in the field of home economics, job applicants must carry their message in person to potential employers. Employers must be taught that persons with home economics degrees have the capabilities and qualifications to fill a variety of positions. b) In may of 1977, Vocational Education Coalition was established by American Home economics association (AHEA), American Vocational Association, and Home Economics Education association This coalition defined the vocational education as occupation of homemaking and paid employment in home economics occupations for women and men. 2. Home Economics in business: Twelve percent of the total membership of the AHEA is affiliated with the home economics in business section. A professional management consultant, Dr. strain's viewpoint and corning Glass Work's case about business value in the home economics were summarized; a) Why a business employs a home economist. b) Why a business does not employ a home economist. c) Enhancing the home economist's value. d) Home economist's roles in corning Glass works. 3. Creating a Career: a) Mrs. Maineri's story. b) Family financial counselors. c) Home economist and displaced homemaker. d) Job opportunities in international services. Since the role of home economics in Korea has had little perception in professionalism, the following issues require immediate and serious attention to enhance career opportunities for home economists: Employers and government's recognition of home economist's value, Home economist's attitude to enhance their value, Fair employment and sex discrimination, Curricula adjustment, and Support from women's organization for employment opportunities, fair treatment, top jobs, etc.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7875-7882
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• 2015

Background: The objectives of this study were to evaluate the expression of brain and acute leukemia, cytoplasmic (BAALC) gene and erythroblast transformation-specific related gene (ERG) in de novo cases of acute myeloid leukemia (AML) and identify roles in disease progression and outcome. Materials and Methods: This study included 50 newly diagnosed AML patients, along with 10 apparently healthy normal controls. BAALC and ERG expression was detected in the bone marrow of both patients and controls using real-time RT-PCR. Results: BAALC and ERG expression was detected in 52% of cases but not in any controls. There was a statistically significant correlation between BAALC and ERG gene expression and age (p-value=0.004 and 0.019, respectively). No statistical significance was noted for sex, lymphadenopathy, hepatomegaly, splenomegaly, other hematological findings, immunophenotyping and FAB sub-classification except for ERG gene and FAB (p-value=0.058). A statistical significant correlation was found between response to treatment with ERG expression (p-value=0.028) and age (p-value=0.014). A statistically significant variation in overall survival was evident with patient age, BM blast cells, FAB subgroups, BAALC and ERG expression (p-value=<0.001, 0.045, 0.041, <0.008 and 0.025 respectively). Conclusions: Our results suggest that BAALC and ERG genes are specific significant molecular markers in AML disease progression, response to treatment and survival.

• Journal of Families and Better Life
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• v.34 no.2
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• pp.29-50
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• 2016

This study aims to find out tendencies of transition of family values in newspapers which were published in May. The study was conducted on content analysis of Chosun and Donga daily newspapers in odd dates of May from 1970 to 2014. Based on preceding research, family values were classified into sub areas such as 'Value of Family,' 'Value of Marriage,' 'Value of Children,' 'Value of Filial Piety' and 'Value of Sex Role.' The collected articles were classified into five sub areas. This study collected 288 articles considering overlap count. According to the study, the newspapers seem to be interested in 'Value of Family' and 'Value of Children', but not 'Value of Marriage'. And academic, social, political efforts to improve family life or raise a necessity to change family values can evoke mass media's interest about family values. Meanwhile, some newspaper articles appear to support an opinion that 'The Healthy Families Act' postulates a claim like 'the traditional family is a normal family'. It seems that newspapers misunderstood about 'The Healthy Families Act.' So we should judge what is more right between two opinions because mass media can reconstruct reality. The tendency of transition of family values is actually slight or the tendency of family values in newspapers cannot show actual family values. Moreover, we have to reconsider that highlighting just 'paternity' can make men overlook other roles in the household like caring for children or cleaning.

• Journal of the Korean Home Economics Association
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• v.45 no.3
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• pp.57-69
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• 2007

The purpose of this study is to examine the impacts of the physical health on health behaviors of the rural elderly. In this study, physical health is measured self-rated health and farmer symptoms. The specific questions addressed in this study are: What are the general tendencies of health behavior, self-rated health and farmer symptoms? What are the direct impacts and indirect impacts of respondents' characteristics, self-rated health and farmer symptoms on health behaviors of the rural elderly? For this purpose, survey data was gathered from 881 rural elderly who live in a village. The statistical methods used for data analysis were descriptive statistics, correlations, and path analysis with spsswin 12.0 program. The major findings of this study are as follows: The level of health behaviors and self-rated health is low and the level of farmer symptoms is high. In general, it can be said that respondents of this study have the low level of physical health and health behaviors. A path analysis shows the relation of variables, which influence on health behaviors. Economic status, education status and farmer symptoms play direct and positive effects on health behaviors. Especially, the effect of farmer symptoms is more important than the others. Sex and age are indirectly significant on health behavior. The results obtained from the study confirm that objective physical health, like as farmer symptoms, plays important roles in health behavior of the rural elderly. It means that the Korean rural elderly need many facilities and services to promote their physical health.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3437-3441
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• 2012

Background: Oncogenic Bmi-1 (B-lymphoma Moloney murine leukemia virus insertion region-1) belongs to the Polycomb-group (PcG) family of proteins and plays an important role in the regulation of proliferation, senescence, cell cycle and apoptosis, chromosome stability, activation of gene transcription. Methods: To clarify the roles of Bmi-1 in tumourigenesis and progression of gastric carcinomas, it was examined by immunohistochemistry (IHC) and real-time RT-PCR in gastric carcinomas, dysplasia, intestinal metaplasia (IM), and gastritis with a comparison of its expression with clinicopathological parameters of carcinomas. Results: There was gradually increased Bmi-1 protein expression from gastritis, IM, dyplasia to carcinoma (p<0.001). Bmi-1 expression was positively linked to tumor size, depth of invasion, lymph node metastasis and worse prognosis of carcinomas (p<0.001), but not to age or sex of carcinoma patients (p>0.05). There was higher Bmi-1 protein expression in intestinal-type carcinomas than diffuse-type ones (p<0.001). At mRNA level, Bmi-1 protein expression was increased from gastritis, IM, dysplasia and carcinoma (p<0.001). Bmi-1 overexpression was observed in gastric carcinoma with larger diameter, deeper invasion, lymph node metastasis, and intestinal-type carcinoma (p<0.05). Conclusion: These findings indicate that up-regulated Bmi-1 expression is positively linked to pathogenesis, growth, invasion, metastasis and differentiation of gastric carcinomas. It was considered as a promising marker to indicate the aggressive behaviors and prognosis of gastric carcinomas.

• Journal of the Korean Society of Costume
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• v.50 no.8
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• pp.177-198
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• 2000

The major purpose of this study is to obtain the evident and visual data about the changes of Korean dress with a socio-cultural context through dress depicted in the Korean films since the 1960s. For this purpose, after were Korean socio-cultural background including the history of Korean films and mass fashion trends reviewed, total fifteen Korean films by ten year were selected on the basis of contemporaneity popularity, and fashionability, and analyzed with the data reviewed before. And the results can be summarized as follows : Dress in the Korean films of the 1960s shows sporty casual took influenced by western style, with the popularity of young fashion and youth film. The typical styles are sac dress and mini skirt fur women, and suit with American silhouette for men. Unisex mode including slim T-shirts and blue jeans with European silhouette supt appears mainly in the Korean films of the 1970s, with the change of sex roles and mass fashion trend. Dress in the Korean films of the 1980s is characterized by bold silhouette and decorative details. with the boom of erotic metro-drama and luxurious fashion trend, such as padded jacket, X silhouette ensemble, brig look coat for women, and American style suit for men. Dress in the Korean films of the 1990s shows the rapid cycle of fashion with the increase of casual wear, reflecting the popularity of romantic comedy film and various socio-cultural circumstances. As a result, the current of dress depleted in the Korean films since the 1960s is summarized as the cycle of fashion accelerated, the similarity between men's and women's wear, and the increase of sporty casual wear. Also, dress in the films reflects effectively the socio-cultural context related to fashion except for especially emphasizing characters in films.

• Journal of Nutrition and Health
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• v.43 no.4
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• pp.357-366
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• 2010

There has been no genome-wide association study (GWAS) for macronutrient intake as a quantitative trait. To explore genetic loci associated with total calorie and macronutrient intake, genome-wide association data of autosomal single nucleotide polymorphisms (SNPs) from Korean adults were analyzed. We conducted a GWAS in 3,690 men and women aged 40 to 60 years from an urban population-based cohort. At the baseline examination (June 18, 2001 through January 29, 2003), DNA samples of the study subjects were collected and analyzed for genotyping. The information of average daily consumption of total calorie, carbohydrate, protein, and fat was obtained from a semi-quantitative food frequency questionnaire and transformed by natural logarithm for analyses after adjustment of calorie intake. Using multivariate linear regression analysis adjusted for age, sex, and height, we tested for 352,021 SNPs and found weak associations, which do not reach genome-wide association significance, with calorie and macronutrient intake. However, a number of SNPs were found to have potential associations with macronutrient intake; in particular, signals in SORBS1 and those in PRKCB1 were likely associated with carbohydrate and fat intake, respectively. We observed an inverse association between the minor allele of the SNPs in these genes and the amount of consumption of carbohydrate or fat. Our GWAS identified loci and minor alleles weakly associated with macronutrient intake. Because SORBS1 and PRKCB1 are reportedly associated with the metabolism of glucose and lipid as well as with obesity-related diseases, further investigations on biological and functional roles of polymorphism of these genes in the relation to macronutrient intake are warranted.