• The Transactions of the Korea Information Processing Society
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• v.5 no.1
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• pp.33-39
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• 1998

A queueing model for performance evaluation of finite buffered inter-node communication system is proposed in this paper. Each components are modeled as M/M/I/B queues to obtain the steady state probabilities and ar-rival rate and to analyze finite buffer behavior, The overall sysrem is integrated as series queues with blocking. Average delay and throughput are the performance measures studied in this analysis. The analytical results are first validated through simulation. Next, the effect of buffer length is discussed using the proposed model.

• Journal of Integrative Natural Science
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• v.10 no.4
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• pp.202-208
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• 2017

Xanthine Oxidase is an enzyme, which oxidizes hypoxanthine to xanthine, and xanthine to uric acid. It is widely distributed throughout various organs including the liver, gut, lungs, kidney, heart, brain and plasma. It is involved in gout pathogenesis. Hence, in the present study, Hologram based Quantitative Structure Activity Relationship Study was performed on a series of Xanthine Oxidase antagonist named 2-(indol-5-yl) thiazole derivatives. The best HQSAR model was obtained using Atoms, Bonds, Connection, Hydrogen, Chirality and Donor Acceptor as fragment distinction parameter using hologram length 71 and 4 components with fragment size of minimum 2 and maximum 5. Significant cross-validated correlation coefficient ($q^2$= 0.563) and non cross-validated correlation coefficients ($r^2$= 0.967) were obtained. The model was then used to evaluate the six external test compounds and its $r^2{_{pred}}$ was found to be 0.798. Contribution map show that presence of propyl ring in indole thiazole makes big contributions for improving the biological activities of the compounds. We hope that our HQSAR model and analysis will be helpful for future design of xanthine oxidase antagonists.

• Journal of Integrative Natural Science
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• v.10 no.4
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• pp.209-215
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• 2017

CXC chemokine receptor 2 (CXCR2) is a prominent chemokine receptor on neutrophils. CXCR2 antagonist may reduce the neutrophil chemotaxis and alter the inflammatory response because the neutrophilic inflammation in the lung diseases is found to be largely regulated through CXCR2 receptor. Hence, in the present study, Topomer based Comparative Molecular Field Analysis (Topomer CoMFA) was performed on a series of CXCR2 antagonist named pyrimidine-5-carbonitrile-6-alkyl derivatives. The best Topomer COMFA model was obtained with significant cross-validated correlation coefficient ($q^2$ = 0.487) and non cross-validated correlation coefficients ($r^2$ = 0.980). The model was evaluated with six external test compounds and its $r^2{_{pred}}$ was found to be 0.616. The steric and electrostatic contribution map show that presence of bulkier and electropositive group around cyclopropyl ring may contribute more for improving the biological activities of these compounds. The generated Topomer CoMFA model could be helpful for future design of novel and structurally related CXCR2 antagonists.

• Journal of Integrative Natural Science
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• v.10 no.4
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• pp.192-196
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• 2017

Xanthine Oxidase is an enzyme, which oxidizes hypoxanthine to xanthine, and xanthine to uric acid. It is widely distributed throughout various organs including the liver, gut, lungs, kidney, heart, brain and plasma. It is involved in gout pathogenesis. Hence, in the present study, topomer based Comparative Molecular Field Analysis (topomer CoMFA) was performed on a series of Xanthine oxidase antagonist named 2-(indol-5-yl) thiazole derivatives. The best topomer CoMFA model was obtained with significant cross-validated correlation coefficient ($q^2$ = 0.572) and non cross-validated correlation coefficients ($r^2$ = 0.937). The model was evaluated with six external test compounds and its $r^2{_{pred}}$ was found to be 0.553. The steric and electrostatic contribution map show that presence of bulky and electropositive group in indole thiazole ring is necessary for improving the biological activities of the compounds. The generated topomer CoMFA model could be helpful for future design of novel and structurally related xanthine oxidase antagonists.

• Nuclear Engineering and Technology
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• v.30 no.1
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• pp.26-39
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• 1998

The containment pressure and temperature transient analysis computer code CONTEMPT4/MOD5 is modified to incorporate the passive containment cooling models. The correlations are selected from the existing experimental heat transfer correlations to model the natural and mixed convection in annular space between the containment shell and the shield building. The evaporative heat transfer of the water film on the outer shell of the containment is modeled using the correlations derived from the analogy between the heat and mass transfer. The modified code is applied to the Ap600 containment transient analysis for the model verification and the results are compared to the results of GOTHIC calculation done by Westinghouse. Also, d series of parametric sensitivity studies of heat transfer correlations, water film ratio and delay time of the wet cooling on the containment peak pressure and temperature following LOCA are performed for the containment of 1000MWe passive plant, KP1000.

• Structural Engineering and Mechanics
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• v.20 no.3
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• pp.335-346
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• 2005

The T-stress of cracks in elastic sheets is solved by using the fractal finite element method (FFEM). The FFEM, which had been developed to determine the stress intensity factors of cracks, is re-applied to evaluate the T-stress which is one of the important fracture parameters. The FFEM combines an exterior finite element model with a localized inner model near the crack tip. The mesh geometry of the latter is self-similar in radial layers around the tip. The higher order Williams series is used to condense the large numbers of nodal displacements at the inner model near the crack tip to a small set of unknown coefficients. Numerical examples revealed that the present approach is simple and accurate for calculating the T-stresses and the stress intensity factors. Some errors of the T-stress solutions shown in the previous literature are identified and the new solutions for the T-stress calculations are presented.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 1997.10a
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• pp.115-120
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• 1997

System identification is the task of inferring a mathematical description of a dynamic system from a series of measurements of the system. There are several motives for establishing mathematical descriptions of dynamic systems. Typical applications encompass simulation, prediction, fault diagnostics, and control system design. The paper demonstrates that neural networks can be used effective for the identification of nonlinear dynamical systems. The content of this paper concerns dynamic neural network models, where not all inputs to and outputs from the networks are measurable. Only one model type is treated, the well-known Innovation State Space model(Kalman Predictor). The identification is based only on input/output measurements, so in fact a non-linear Extended Kalman Filter problem is solved. Even for linear models this is a non-linear problem without any assurance of convergence, and in spite of this fact an attempt is made to apply the principles from linear models, an extend them to non-linear models. Computer simulation results reveal that the identification scheme suggested are practically feasible.

• The Journal of Information Systems
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• v.10 no.2
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• pp.151-164
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• 2001

현재의 항공사 기내식 수요예측 시스템으로는 항공기 운항의 지연이나 초과 주문으로 인한 손실 문제를 해결하기 힘든 것으로 알려져 있다. 이러한 문제를 해결하기 위해 본 연구에서는 항공기 기내식 시계열 자료만을 입력변수로 사용한 단순인공신경망모형(simple neural network model), 단순인공신경망모형에 전통적인 시계열 기법(본 연구에서는 지수 평활법)의 예측 결과를 입력변수로 추가한 혼합인공신경망모형(hybrid neural network model), 그리고 혼합인공신경 망 모형에 상관관계가 높은 다른 시계열 자료(본 논문에서는 유사 노선의 다른 항공기 기내식 시계열 자료)를 인공신경망의 입력변수로 추가시킨 하이퍼혼합인공신경망모형(hyper hybrid neural network model)을 새로운 항공기 기내식 수요예측 기법으로 제안하고, 이들 모형의 예측력을 비교 분석하였다. 분석 결과 하이퍼혼합인공신경망 모형의 예측력이 가장 우수한 것으로 나타나, 인공신경 망을 기반으로 한 수요예측에 있어 상관관계가 높은 다른 시계열 자료를 입력변수로 추가함으로써 인공신경망모형의 예측력을 개선시킬 수 있음을 알 수 있었다

• KIEAE Journal
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• v.4 no.3
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• pp.27-35
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• 2004

The conventional way to acquire sufficient amount of daylight in interiors is to provide large openings with clear glass. The use of clear glass on the whole facade, however, might cause a sort of visual problem because of the harness of direct sun and brighter sky surface than expected. They should be filtered in opticalway or bounced in the architectural. One of the common solutions for the problem might be the use of photometric glasses with various transmittances for the glass walls. This paper deals with performance data related to the impact of various transmittal glazing materials for window systems in terms of daylighting. A series of scale model measurements was carried out with the fundamental configuration of a commonly used all-glass facades. Additionally some experimental performance index was issued for the better expression of the need of natural lighting.

• 제어로봇시스템학회:학술대회논문집
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• 2001.10a
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• pp.124.3-124
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• 2001

The nonlinearity of several chemical processes is usually approximated by a series of the nonlinear static element and the linear subsystem. In the case of the model that the nonlinear static element precedes the linear subsystem, it is called a Hammerstein model. It is a Wiener model when the order is reserved. Here we investigate a relay feedback identification method for Hammerstein type nonlinear processes. The proposed method separates the identification of the nonlinear static function from that of the linear subsystem by using a relay feedback method. From two times activation of nonlinear processes, we identify he whole range of the nonlinear static function as well as the ultimate information of the linear subsystem.