• Clinical and Experimental Pediatrics
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• 제54권8호
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• pp.350-353
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• 2011

A 47-day-old male infant presented with fever, poor oral intake, irritability, and right-sided bluish buccal swelling. Contrast-enhanced computed tomography of the neck showed a round mass lesion of about $2.0{\times}1.5cm$ that suggested abscess formation in the right masticator space. Ultrasound-guided extraoral aspiration of the abscess at the right masseter muscle was successful. Staphylococcus aureus was identified in the culture from the aspirated pus and blood. Appropriate antibiotics were given and the patient recovered. The patient underwent follow-up ultrasonography that showed an improved state of the previously observed right masseter muscle swelling at about 1 month after hospital discharge. A masticator space abscess usually originates from an odontogenic infection in adults. We report a case of masticator space abscess in a 47-day-old infant in whom septicemia without odontogenic infection was suspected.

• Pediatric Infection and Vaccine
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• 제26권3호
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• pp.188-193
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• 2019

b형 헤모필루스 인플루엔자균 예방접종이 시행된 이후 b형 헤모필루스 인플루엔자균에 의한 감염률은 급격히 감소하였으나, non-b형 헤모필루스 인플루엔자균에 의한 감염의 비율이 증가하는 추세이다. 대뇌 정맥동 혈전증은 드물지만 세균성 수막염의 합병증 중 하나로 발생할 수 있다. 대뇌 정맥동 혈전증이 동반된 f형 헤모필루스 인플루엔자균에 의한 뇌수막염 환자를 진단 및 치료하였기에 보고하는 바이다.

• 한국수산과학회지
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• 제51권3호
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• pp.328-331
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• 2018

We developed and subsequently characterized mouse monoclonal antibodies (MAbs) against nervous necrosis virus (NNV, RGNNV genotype). We established six hybridoma clones secreting MAbs against NNV antigen: 2B1, 2B11, 2C12, 13C1-1, 13C1-2 and 14D11. All six MAbs belonged to the IgG2a isotype with a kappa light chain and their reactivity recognized against the 41 kDa coat protein of NNV by Western blot analysis. The affinity constants of the six MAbs were measured by enzyme-linked immunosorbent assay (ELISA). All six MAbs reacted with two NNV isolates (SgNag05 and Gemunodo06), while no reactivity was observed with five know fish viruses, namely marine birnavirus, infectious pancreatic necrosis virus, viral hemorrhagic septicemia virus, hirame rhabdovirus, and infectious hematopoietic necrosis virus. Moreover, high ELISA optical density (OD) values (0.87-1.42) were observed in the brain tissues of NNV-infected sevenband grouper, while low OD values (less than 0.12) were recorded in the brain tissues of uninfected fish. These results suggest that these six MAbs are highly competent and useful for the detection of NNV with the RGNNV genotype.

• 한국수산과학회지
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• 제53권5호
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• pp.688-693
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• 2020

Vibrio vulnificus is a Gram-negative marine bacterium known to cause septicemia. This study was conducted to investigate the distribution of V. vulnificus along the coast of Gadeok Island in Korea and to determine the molecular characteristics of isolated strains sampled between March and November 2019 from seawater. The strains were mostly detected between July and September, when the average water temperature and average salinity were 22.2-26.2℃ and 14.2-29.9 psu, respectively. V. vulnificus was not detected in seawater below 15℃. In September, the highest population of V. vulnificus was observed at 2,100 MPN (most probable number)/100 mL, attributable to decreased salinity from heavy rains. In addition, the detection rate of V. vulnificus was higher at the sampling station near the Nakdong River. Virulence-related genes were also identified among the isolates, such as vvhA (97.1%), viuB (44.1%), and vcgC (57.4%). In particular, viuB and vcgC were only observed in V. vulnificus isolated from June to September, when the detection rate was high and water temperature was above 20℃, suggesting the role of seasonal characteristics.

• 한국수산과학회지
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• 제52권6호
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• pp.625-630
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• 2019

The pathogenic Vibrio genus contains halophilic bacteria that are distributed in marine and freshwater environments. Vibrio cholerae, Vibrio vulnificus, and Vibrio parahaemolyticus are potent human pathogens and leading causes of septicemia, wound infection, and seafood-borne gastroenteritis. The aim of this study was to investigate the presence of pathogenic Vibrio species in seawater off the west coast of Korea. Sixty-four seawater samples were obtained from different sites in Gomso Bay and Byeonsan from April 2018 to November 2018. Pathogenic Vibrio species were detected using a combination of most probable number (MPN)-polymerase chain reaction methods. V. cholerae, V. vulnificus, and V. parahaemolyticus were found in 0.0%, 20.3%, and 65.6% of seawater samples, respectively. Quantitative results revealed 3.6-23 MPN/100 mL of V. vulnificus, and 3.6-930 MPN/100 mL of V. parahaemolyticus in the samples. Overall, these results provide new insight into the necessity for seawater sanitation in Gomso Bay and Byunsan; they also provide evidence that will help reduce outbreaks of seafood-borne illness caused by pathogenic Vibrio species.

• 대한수의학회지
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• 제36권3호
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• pp.621-626
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• 1996

The changes of concentration of serum haptoglobin, body temperature, hematological result and antibody titers were compared in pigs given intravenously injection of E rhusiopathiae and control pigs. Pigs administered with E rhusiopathiae injections showed acute septicemia and arthritis. Also, statistically significant changes observed in the total white cell counts and body temperature. An increased haptoglobin concentration in serum was detected after E rhusiopathiae infection, but not during antibiotics treatment. The results indicated that measurement of the concentration of serum haptoglobin may be useful in the early diagnosis of infectious disease, such as Erysipelas.

• 한국수정란이식학회지
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• 제32권4호
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• pp.325-329
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• 2017

A 2-year-old female Maltese dog was admitted with a history of pyometra and resulting peritonitis and septicemia. Uterine specimen sampled by ovariohysterectomy was processed routinely for histopathological observation. Grossly, the uterine mucosa was covered with necrotic debris and on the cut surface, lesion extended into the uterine wall. Microscopically, severe necrosis was observed throughout thickened mucosa, submucosa, and wall of uterus. Tumorous lesions composed of anaplastic cells with bizarre nuclei or tubular structures of cuboidal to short columnar cells were infrequently observed around the necrotic lesions and muscular layer far from necrotic areas. Immunohistochemically, central necrotic area with ambiguous cell and tissue structures, peri-necrotic tumor lesions, and muscular layer were strongly positive for cytokeratin. Since huge necrosis of adenocarcinoma lesions in this case made it difficult to diagnose, immunohistochemical results enable to diagnose as a severe necrotizing adenocarcinoma. Thus, histopathological and immunohistochemical findings in this case may serve as an important knowledge to diagnose uterine adenocarcinoma with huge necrosis in the veterinary field.

• 한국어병학회지
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• 제21권1호
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• pp.21-27
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• 2008

2006년　5월　전북　군산시에　위치한　미꾸라지　양식장에서　미꾸라지가 대량으로 폐사하였다.　병어는　궤양을　동반한　체표의　출혈반점과　아가미　빈혈　및　울혈　있었고　간의　퇴색과　비장, 신장의　종대　및　장의　출혈이　나타났다. 병어의 간, 비장, 신장에서　그람음성의　단간균이　검출되었고　생화학적　시험측정　결과　분리균은 Aeromonas sobria로　판명되었다. 분리균과 A. sobria가 소유한 aerolysine 유전자　일치　여부를 분석한 결과 같은　유전자를　가지고　있음이　판명되었다. 분리균을　미꾸라지에　농도별로　복강주사　한　결과　자연발생어의 증상과　일치하였다. 그럼으로 A. sobria는 양식　미꾸라지의 새로운 세균성　질병의 원인균이 될 가능성이 높다고 판단된다.

• 한국어병학회지
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• 제16권2호
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• pp.81-90
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• 2003

High mortality with signs similar to viral haemorrhagic septicemia (VHS) such as severe haemorrhages in the skin, muscle and air bladder occurred in the farmed adult rainbow trout, Oncorhynchus mykiss, in Ku-mi and Je-chun area in Korea. The isolates were neutralized by an antiserum against IHNV but not by antisera against VHSV. Electron micrograph of an ultrathin section showed large numbers of bullet-shaped virus particles. The newly isolated rhabdovirus was composed of five structural proteins. In the western blot analysis Ihe anti-DiNV serum strongly reacted with G. N and MI protein. The cumulative mortalities of RTK infected rainbow trout (10-12cm.9-12g) with $10^{3.5}\;and\;10^{1.5}TCID_{50}/m{\ell}$ were 80% and 30%. respectiveIy_ RTJ infected fish showed 50% mortality by infection with $10^{3.5}TCID_{50}/m{\ell}$. Control group and IHNVChAb exhibited no mortality. From these results, the viruses were identified lHNV although diseased fish showed similar sign. with VHS and caused high mortality in large-sized fish.

• Journal of Chest Surgery
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• 제30권8호
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• pp.823-826
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• 1997

심근 농양은 대개 감염성 심내막염이나 패혈증의 합병증으로 생길 수 있다. 심근 농양이 관상 동맥을 압박 하여 심근 허혈을 초래한 경우는 1987년 Cripps 등이 보고한 이래 5-6례 있을뿐이다. 61세 남자 환자가 내원 6주 전부터 시작된 원인을 알 수 없는 발열과 오한을 주소로 내원하였다. 환자는 발열이 시작된지 2주후에 심실 세동 및 이로 인한 심장 마비로 심폐소생술을 시행받은 병력이 있었다. 심에코와 관상동맥 조영 결과 우측 방실구 부위의 심근 농양이 우관상동맥을 외부에서 압박하면서 심근 경색을 초래한 소견을 보였다. 수 술은 농양을 변연 절제하였으며 괴사된 심방벽을 절제한 후 생긴 결손은 자가 심낭을 이용한 patch로 폐쇄하 였고 우측 내유동맥을 우관상동맥의 원위부에 문합하였다. 환자는 합병증없이 퇴원하였으며 수술 중 검체에 서 시행한 농양배양 검사에서는 Salmonella arizona가 동정되었다.