• Title/Summary/Keyword: separated optimization

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Real-time identification of the separated lanthanides by ion-exchange chromatography for no-carrier-added Ho-166 production

  • Aran Kim;Kanghyuk Choi
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.7 no.2
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    • pp.69-77
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    • 2021
  • No-carrier-added holmium-166 (n.c.a 166Ho) separation is performed based on the results of separation conditions using stable isotopes dysprosium (Dy) and holmium (Ho) to minimize radioactive waste from separation optimization procedures. Successful separation of two adjacent lanthanides was achieved by cation-exchange chromatography using a sulfonated resin in the H+ form (BP-800) and α-hydroxyisobutyric acid (α-HIBA) as eluent. For the identification process after separation of stable isotopes, the use of chromogenic reagents alternatively enables on-line detection because the lanthanides are hardly absorb light in the UV-vis region or exhibit radioactivity. Four different chromogenic reagents were pre-tested to evaluate suitable coloring reagents, of which 4-(2-Pyridylazo)resorcinol is the most recommendable considering the sensitivity and specificity for lanthanides. Lanthanide radioisotopes (RI) were monitored for separation with an RI detector using a lab-made separation LC system. Under the proper separation conditions, the n.c.a 166Ho was effectively obtained from a large amount of 100 mg dysprosium target within 2 hrs.

Dual-loss CNN: A separability-enhanced network for current-based fault diagnosis of rolling bearings

  • Lingli Cui;Gang Wang;Dongdong Liu;Jiawei Xiang;Huaqing Wang
    • Smart Structures and Systems
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    • v.33 no.4
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    • pp.253-262
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    • 2024
  • Current-based mechanical fault diagnosis is more convenient and low cost since additional sensors are not required. However, it is still challenging to achieve this goal due to the weak fault information in current signals. In this paper, a dual-loss convolutional neural network (DLCNN) is proposed to implement the intelligent bearing fault diagnosis via current signals. First, a novel similarity loss (SimL) function is developed, which is expected to maximize the intra-class similarity and minimize the inter-class similarity in the model optimization operation. In the loss function, a weight parameter is further introduced to achieve a balance and leverage the performance of SimL function. Second, the DLCNN model is constructed using the presented SimL and the cross-entropy loss. Finally, the two-phase current signals are fused and then fed into the DLCNN to provide more fault information. The proposed DLCNN is tested by experiment data, and the results confirm that the DLCNN achieves higher accuracy compared to the conventional CNN. Meanwhile, the feature visualization presents that the samples of different classes are separated well.

Study on the Optimization of Hybrid Network Topology for Railway Cars (철도 차량용 하이브리드 네트워크 토폴로지 최적화 연구)

  • Kim, Jungtai;Yun, Ji-Hoon
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.4
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    • pp.27-34
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    • 2016
  • In the train system, railway vehicles are connected in a line. Therefore, this feature should be considered in composing network topology in a train system. Besides, inter-car communication should be distinguished from in-car communication. As for the inter-car communication, the hybrid topology was proposed to use rather than the conventional ring, star, daisy-chain, and bus topologies. In the hybrid topology, a number of cars are bound to be a group. Then star topology is used for the communication in a group and daisy-chain topology is used for the communication between groups. Hybrid topology takes the virtue of both star and daisy-chain topologies. Hence it maintains communication speed with reducing the number of connecting cables between cars. Therefore, it is important to choose the number of cars in a group to obtain higher performance. In this paper, we focus on the optimization of hybrid topology for railway cars. We first assume that the size of data and the frequency of data production for each car is identical. We also assume that the importance for the maximum number of cables to connect cars is variable as well as the importance of the communication speed. Separated weights are granted to both importance and we derive the optimum number of cars in a group for various number of cars and weights.

Preparation of Cosmeceuticals Containing Broussonetia kazinoki Extracts: Optimization Using Central Composite Design Method (닥나무 추출물이 함유된 Cosmeceuticals의 제조: 중심합성계획모델을 이용한 최적화)

  • Hong, Seheum;Park, Bo Ra;Lee, Seung Bum
    • Applied Chemistry for Engineering
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    • v.29 no.6
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    • pp.682-689
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    • 2018
  • In this paper, the stability criteria of cosmeceuticals emulsion containing Broussonetia kazinoki extracts was established using the central composite design model. As optimization conditions of the emulsification using the central composite design model, concentrations of the emulsifier and emulsion stabilizer were used as a quantitative factor while emulsion stability index (ESI) and polydispersity index (PDI) were used as a reaction value. The targeted values of ESI and PDI were estimated as over 60% and the minimum number, respectively. Optimized concentrations of the emulsifier and emulsion stabilizer were 3.73 and 3.07 wt%, respectively, from the emulsification optimization based on ESI and PDI values. The estimated reaction values of ESI and PDI were 60% and 0.585, respectively. As concentrations of the emulsifier and emulsion stabilizer increased, the stability of the emulsion prepared tended to increase. The emulsifier was one of the most influential factors for ESI than the emulsion stabilizer. On the other hand, the PDI value was similarly affected by both the emulsion and emulsion stabilizer. The ESI of the cosmeceuticals emulsion prepared under experimental conditions deduced from the central synthesis planning model showed at least about 45% of the stability. However, all of the emulsions were separated after 4 weeks from the initial preparation. When the concentration of the emulsifier was more than 3.72 wt%, the ESI value was over 60%. Also the layer separation rate decreased with increasing the emulsion stabilizer concentration.

Influence of Sustaining Frequency on the luminous Efficiency in AC-PDP (교류형 플라즈마 디스플레이에 있어서 유지방전 주파수에 따른 발광 효율에 미치는 영향)

  • 정의선;김대일
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.14 no.6
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    • pp.1-5
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    • 2000
  • Recently alternating-current Plasma Display Panel(AC-PDP) is in the spotlight as a digital television and high definition television. The panel structure widely adapted in commercial AC-PDP is three electrodes surface discharge type. At present time, the luminous efficiency is around 1lm/W, it should be a key factor for the commercialization. For the high luminous efficiency, the development of panel structure is necessary. At a given panel structure, a driving method should be optimized to get a sufficient luminous efficiency. The display image of AC-PDP could be realized by the repeated light emission from the discharge. Because most of discharge power is consumed in the sustaining period, the optimization of sustaining waveform is very important for the high luminous efficiency. ADS (Address and Display period Separated) driving method is commonly used. The average driving frequency of ADS driving method is ranged by several tens kilo of [kHz], however the actual frequency of sustaining period is in range of 100[kHz] to 200[kHz]. Based on this study, when the phosphor emits the visible light, it has a decay time of few milliseconds due to the material transfer to the phosphor to emit the visible light. Consequently the luminous efficiency decreases in proportion to the driving frequency. It is found that the luminous efficiency could be significantly improved by the low frequency sustaining driving method.

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Optimization of KOH pretreatment conditions from Miscanthus using high temperature and extrusion system (고온 압출식 반응시스템을 이용한 억새 바이오매스의 KOH 전처리조건 최적화)

  • Cha, Young-Lok;Park, Sung-Min;Moon, Youn-Ho;Kim, Kwang-Soo;Lee, Ji-Eun;Kwon, Da-Eun;Kang, Yong-Gu
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.4
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    • pp.1243-1252
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    • 2019
  • The purpose of this study is to investigate the optimum conditions of biomass pretreatment with potassium hydroxide (KOH) for efficient utilization of cellulose, hemicellulose and lignin from Miscanthus. The optimization of variables was performed by response surface methodology (RSM). The variation ranges of the parameters for the RSM were potassium hydroxide 0.2~0.8 M, reaction temperature 110~190℃ and reaction time 10~90 min. The optimum conditions of alkali pretreatment from Miscanthus were determined as follows: concentration of KOH 0.47 M, reaction temperature 134℃ and reaction time 65 min. At the optimum conditions, the yield of cellulose from the solid fraction after pretreatment was predicted to be 95% by model prediction. Finally, 66.1 ± 1.1% of cellulose were obtained by verification experiment under the optimum conditions. The order contents of solid extraction were hemicellulose 26.4 ± 0.4%, lignin 3.7 ± 0.1% and ash 0.5 ± 0.04%. The yield of ethanol concentration of 96% was obtained using separated saccharification and fermentation.

The optimization of extraction process on hemicellulose from rice bran (미강유래 식이섬유 헤미셀룰로오스의 추출 공정 최적화)

  • Jung, Ji-Eun;Choi, Yong-Hee
    • Food Science and Preservation
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    • v.15 no.4
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    • pp.532-541
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    • 2008
  • A central composite design was applied to investigate the effects of the independent variables of NaOH concentration(X1) and extraction time(X2) on dependent variables such as Yield(Y1), Xyl/Ara ratio(Y2), uronic acid(Y3), $\beta$-glucan(Y4) and total sugars(Y5) of hemicelluloses separated from rice bran. The Coefficients of determination(R2) in various models ranged from 0.8626 to 0.9319. Yield increased with increased NaOH concentration and extraction time. The optimum extraction conditions were NaOH concentration at 2.45M and extraction time of 24.2 h. Predicted values at the optimized conditions were acceptable, compared with experimental values. The structural characteristics of an optimum hemicellulose extract were explored. As a result, it showed that the surfaces of hemicellulose had a highly irregular reticulated structure. And also it was both small and large molecular particle in the hemicelluloses. Their average molecular weights were in the ranges $235{\sim}240$ kDa and $8.0{\sim}9.4kDa$, respectively.

Optimization of Anion-exchange Chromatography for the Separation of Agarase from Culture Broth of Pseudoalteromonas sp. (Pseudoalteromonas sp. 배양액으로부터 아가레이즈 분리를 위한 음이온교환 크로마토그래피 최적화)

  • Kim, Yu-Na;Lee, Jae-Ran;Kim, Mu-Chan;Kim, Sung-Bae;Chang, Yong-Keun;Hong, Soon-Kwang;Kim, Chang-Joon
    • Korean Chemical Engineering Research
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    • v.49 no.6
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    • pp.840-845
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    • 2011
  • Degradation products of agarose are biologically active and thus used as an ingredient in pharmaceuticals or functional cosmetics. Furthermore, it has been strongly considered as a substrate for bio-ethanol fermentation. Recently, we isolated new agarase-producing microorganism, Pseudoalteromonas sp. from south sea of Korea. In this study, we aimed to separate and purify the agarase from culture broth of this strain. Separation of agarase was performed by ion- exchange chromatography on DEAE-Sepharose resin. Equilibrium pH and volume ratio of resin to the amount of protein were optimized for the efficient adsorption of protein. 410 ${\mu}g$ of protein was completely adsorbed to 3 mL of resin at pH 7.5. The total amount of eluted protein increased as NaCl concentration increased to 400 mM at isocratic elution. Agarase was separated by linear gradient elution of NaCl (0~1,000 mM). Three major protein peaks were observed and the presence or absence of agarase in these eluted proteins was measured by Lugol's staining technique. Only six eluted protein fractions showed strong agarase activity.

Modeling of Wet Flue Gas Desulfurization Process for Utilization of Low-Grade Limestone (저품위 석회석 활용을 위한 습식 배연탈황 공정 모델링 연구)

  • Lim, Jonghun;Choi, Yeongryeol;Kim, Geonyeol;Song, Hojun;Kim, Junghwan
    • Korean Chemical Engineering Research
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    • v.57 no.5
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    • pp.743-748
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    • 2019
  • This study focuses on the simulation of wet flue gas desulfurization process for improving the production of gypsum by the utilization of low-grade limestone. At present, high-grade limestone with a $CaCO_3$ content of 94% is used for producing merchantable gypsum. In modeling process, a lot of reactions are considered to develop model. First, the limestone dissolution is simulated by RSTOIC model. Second, SOx absorption and crystallization is used by RCSTR model. Finally the gypsum is separated by using SEPERATORS model. Modeling steps make it easy to reflect further side reactions and physical disturbances. In optimization condition, constraints are set to 93% purity of gypsum, 94% desulfurization efficiency, and total use of limestone at 3710 kg/hr. Under these constraints, the mass flow of low-grade limestone was maximized. As a result, the maximum blending quantity of low-grade limestone for 2,100 kg of high-grade limestone that satisfies constraints is about 1,610 kg.

Pretreatment condition Optimization of Hydrolysis and Water Absorption Behavior of PET Fibrous Assembly (전처리 조건에 따른 PET 섬유 집합체의 가수분해 및 흡수성 거동 연구)

  • Lee, Jun-Hee;Lee, Kwang-Woo;Seo, Mal-Yong;Kang, Ji-Man;Kim, Book-Sung
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2012.03a
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    • pp.88-88
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    • 2012
  • Applied decanol and nonanol provided more weight loss than applied heptanol and octanol. PET using decanol showed the highest weight loss than other alcohols applied. Sodium hydroxide caused weight loss in PET fabrics because terephthalic acid and ethylene glycol were separated by the hydrolysis of the ester group in the PET chains. The terephthalic acid was neutralized to disodium terephthalate and the reaction results in weight loss in the PET fabrics. The weight loss increased with increasing hydrolysis time because disodium terepthalate was water soluble and the reaction was not reached at equilibrium. Pretreatment alcohols increased water absorption, especially in case of PET applied decanol revealed the highest water absorption. PET applied decanol showed 400% of initial water absorption, and PET applied nonanol revealed 250% of initial water absorption. However, the pristine PET showed 90% initial water absorption, and it revealed 230% maximum water absorption as compared to other alcohols. Also, PET applied decanol, nonanol, octanol and heptanol showed 600%, 400%, 350% and 300% maximum water absorption, respectively. The result implied alcohol length affected on water absorption of PET fibrous assembly. This implies that the microvoid of the PET surface hold water molecules. Surface morphology of PET appears that the pretreatment reagent attacks almost entire surface of the fiber, causing surface etching. As the surface etching progresses, it propagates inside the fiber, resulting in the formation of elongated cavities on the surface.

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