• Title/Summary/Keyword: sentinel

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Prospective Multicenter Feasibility Study of Laparoscopic Sentinel Basin Dissection after Endoscopic Submucosal Dissection for Early Gastric Cancer: SENORITA 2 Trial Protocol

  • Eom, Bang Wool;Yoon, Hong Man;Min, Jae Seok;Cho, In;Park, Ji-Ho;Jung, Mi Ran;Hur, Hoon;Kim, Young-Woo;Park, Young Kyu;Nam, Byung-Ho;Ryu, Keun Won;Sentinel Node Oriented Tailored Approach (SENORITA) Study Group
    • Journal of Gastric Cancer
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    • v.19 no.2
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    • pp.157-164
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    • 2019
  • Purpose: Although standard radical gastrectomy is recommended after noncurative resection of endoscopic submucosal dissection (ESD) for early gastric cancer in most cases, residual tumor and lymph node metastasis have not been identified after surgery. The aim of this study is to evaluate the feasibility of sentinel node navigation surgery after noncurative ESD. Materials and Methods: This trial is an investigator-initiated, multicenter prospective phase II trial. Patients who underwent ESD for clinical stage T1N0M0 gastric cancer with noncurative resections were eligible. Qualified investigators who completed the prior phase III trial (SENORITA 1) are exclusively allowed to participate. In this study, 2 detection methods will be used: 1) intraoperative endoscopic submucosal injection of dual tracer, including radioisotope and indocyanine green (ICG) with sentinel basins detected using gamma-probe; 2) endoscopic injection of ICG, with sentinel basins detected using a fluorescence imaging system. Standard laparoscopic gastrectomy with lymphadenectomy will be performed. Sample size is calculated based on the inferior confidence interval of the detection rate of 95%, and the calculated accrual is 237 patients. The primary endpoint is detection rate, and the secondary endpoints are sensitivity and postoperative complications. Conclusions: This study is expected to clarify the feasibility of laparoscopic sentinel basin dissection after noncurative ESD. If the feasibility is demonstrated, a multicenter phase III trial will be initiated to compare laparoscopic sentinel node navigation surgery versus laparoscopic standard gastrectomy in early gastric cancer after endoscopic resection.

Root cause analys is and improving strategy of suicidal sentinel events (의료기관 내 자살사건의 근본원인분석과 개선전략)

  • Lim, Hun-Sun;Kim, Hong-Soon;Yum, Ho-Kee
    • Quality Improvement in Health Care
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    • v.19 no.2
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    • pp.50-64
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    • 2013
  • Objectives : Suicide is a serious sentinel event in healthcare organization. Suicide and suicidal attempt are fatal and long lasting mental and physical damage to themselves, family, and medical staffs. To develope the system to prevent suicidal accident in hospital, we reviewed and analysed one case of suicidal sentinel event. Methods: The risks of suicidal sentinel event were evaluated and analysed through the root cause analysis and failure mode effects analysis. Result: We found several root causes such as initial assessment of oldest patient and security issues. Couple of action plans to fix the problems were done immediately. According to failure mode, we evaluate the risk priority number to modify the action plans. Conclusion: To reduce the risk of sentinel events, we reviewed the suicidal event and established the new system and action plan to prevent sentinel events.

The Potential of Sentinel-1 SAR Parameters in Monitoring Rice Paddy Phenological Stages in Gimhae, South Korea

  • Umutoniwase, Nawally;Lee, Seung-Kuk
    • Korean Journal of Remote Sensing
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    • v.37 no.4
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    • pp.789-802
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    • 2021
  • Synthetic Aperture Radar (SAR) at C-band is an ideal remote sensing system for crop monitoring owing to its short wavelength, which interacts with the upper parts of the crop canopy. This study evaluated the potential of dual polarimetric Sentinel-1 at C-band for monitoring rice phenology. Rice phenological variations occur in a short period. Hence, the short revisit time of Sentinel-1 SAR system can facilitate the tracking of short-term temporal morphological variations in rice crop growth. The sensitivity of SAR backscattering coefficients, backscattering ratio, and polarimetric decomposition parameters on rice phenological stages were investigated through a time-series analysis of 33 Sentinel-1 Single Look Complex images collected from 10th April to 25th October 2020 in Gimhae, South Korea. Based on the observed temporal variations in SAR parameters, we could identify and distinguish the phenological stages of the Gimhae rice growth cycle. The backscattering coefficient in VH polarisation and polarimetric decomposition parameters showed high sensitivity to rice growth. However, amongst SAR parameters estimated in this study, the VH backscattering coefficient realistically identifies all phenological stages, and its temporal variation patterns are preserved in both Sentinel-1A (S1A) and Sentinel-1B (S1B). Polarimetric decomposition parameters exhibited some offsets in successive acquisitions from S1A and S1B. Further studies with data collected from various incidence angles are crucial to determine the impact of different incidence angles on polarimetric decomposition parameters in rice paddy fields.

Spatio-temporal soil moisture estimation using water cloud model and Sentinel-1 synthetic aperture radar images (Sentinel-1 SAR 위성영상과 Water Cloud Model을 활용한 시공간 토양수분 산정)

  • Chung, Jeehun;Lee, Yonggwan;Kim, Sehoon;Jang, Wonjin;Kim, Seongjoon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2022.05a
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    • pp.28-28
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    • 2022
  • 본 연구는 용담댐유역을 포함한 금강 유역 상류 지역을 대상으로 Sentinel-1 SAR (Synthetic Aperture Radar) 위성영상을 기반으로 한 토양수분 산정을 목적으로 하였다. Sentinel-1 영상은 2019년에 대해 12일 간격으로 수집하였고, 영상의 전처리는 SNAP (SentiNel Application Platform)을 활용하여 기하 보정, 방사 보정 및 Speckle 보정을 수행하여 VH (Vertical transmit-Horizontal receive) 및 VV (Vertical transmit-Vertical receive) 편파 후방산란계수로 변환하였다. 토양수분 산정에는 Water Cloud Model (WCM)이 활용되었으며, 모형의 식생 서술자(Vegetation descriptor)는 RVI (Radar Vegetation Index)와 NDVI (Normalized Difference Vegetation Index)를 활용하였다. RVI는 Sentinel-1 영상의 VH 및 VV 편파자료를 이용해 산정하였으며, NDVI는 동기간에 대해 10일 간격으로 수집된 Sentinel-2 MSI (MultiSpectral Instrument) 위성영상을 활용하여 산정하였다. WCM의 검정 및 보정은 한국수자원공사에서 제공하는 10 cm 깊이의 TDR (Time Domain Reflectometry) 센서에서 실측된 6개 지점의 토양수분 자료를 수집하여 수행하였으며, 매개변수의 최적화는 비선형 최소제곱(Non-linear least square) 및 PSO (Particle Swarm Optimization) 알고리즘을 활용하였다. WCM을 통해 산정된 토양수분은 피어슨 상관계수(Pearson's correlation coefficient)와 평균제곱근오차(Root mean square error)를 활용하여 검증을 수행할 예정이다.

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Optimization of Input Features for Vegetation Classification Based on Random Forest and Sentinel-2 Image (랜덤포레스트와 Sentinel-2를 이용한 식생 분류의 입력특성 최적화)

  • LEE, Seung-Min;JEONG, Jong-Chul
    • Journal of the Korean Association of Geographic Information Studies
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    • v.23 no.4
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    • pp.52-67
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    • 2020
  • Recently, the Arctic has been exposed to snow-covered land due to melting permafrost every year, and the Korea Geographic Information Institute(NGII) provides polar spatial information service by establishing spatial information of the polar region. However, there is a lack of spatial information on vegetation sensitive to climate change. This research used a multi-temporal Sentinel-2 image to perform land cover classification of the Ny-Ålesund in Arctic Svalbard. In the pre-processing step, 10 bands and 6 vegetation spectral index were generated from multi-temporal Sentinel-2 images. In image-classification step is consisted of extracting the vegetation area through 8-class land cover classification and performing the vegetation species classification. The image classification algorithm used Random Forest to evaluate the accuracy and calculate feature importance through Out-Of-Bag(OOB). To identify the advantages of multi- temporary Sentinel-2 for vegetation classification, the overall accuracy was compared according to the number of images stacked and vegetation spectral index. Overall accuracy was 77% when using single-time Sentinel-2 images, but improved to 81% when using multi-time Sentinel-2 images. In addition, the overall accuracy improved to about 83% in learning when the vegetation index was used additionally. The most important spectral variables to distinguish between vegetation classes are located in the Red, Green, and short wave infrared-1(SWIR1). This research can be used as a basic study that optimizes input characteristics in performing the classification of vegetation in the polar regions.

Forest Burned Area Detection Using Landsat 8/9 and Sentinel-2 A/B Imagery with Various Indices: A Case Study of Uljin (Landsat 8/9 및 Sentinel-2 A/B를 이용한 울진 산불 피해 탐지: 다양한 지수를 기반으로 다시기 분석)

  • Kim, Byeongcheol;Lee, Kyungil;Park, Seonyoung;Im, Jungho
    • Korean Journal of Remote Sensing
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    • v.38 no.5_2
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    • pp.765-779
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    • 2022
  • This study evaluates the accuracy in identifying the burned area in South Korea using multi-temporal data from Sentinel-2 MSI and Landsat 8/9 OLI. Spectral indices such as the Difference Normalized Burn Ratio (dNBR), Relative Difference Normalized Burn Ratio (RdNBR), and Burned Area Index (BAI) were used to identify the burned area in the March 2022 forest fire in Uljin. Based on the results of six indices, the accuracy to detect the burned area was assessed for four satellites using Sentinel-2 and Landsat 8/9, respectively. Sentinel-2 and Landsat 8/9 produce images every 16 and 10 days, respectively, although it is difficult to acquire clear images due to clouds. Furthermore, using images taken before and after a forest fire to examine the burned area results in a rapid shift because vegetation growth in South Korea began in April, making it difficult to detect. Because Sentinel-2 and Landsat 8/9 images from February to May are based on the same date, this study is able to compare the indices with a relatively high detection accuracy and gets over the temporal resolution limitation. The results of this study are expected to be applied in the development of new indices to detect burned areas and indices that are optimized to detect South Korean forest fires.

私設電子交換機SENTINEL -500에 대하여

  • 강진구;이주형
    • The Magazine of the IEIE
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    • v.5 no.1
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    • pp.24-30
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    • 1978
  • 시분할다중화방식에 따른 전 전자소자에 의한 통화로 구성과 미니컴퓨터에 의한 축적프로그램 제어방식을 채용한 전전자식 사설전화교환기 SENTINEL-500을 소개 하였다. SENTINEL-500의 표준회선용양은 480가입자회선과 시내중단회선(국선) 100회선을 수용할 수 있으며 약 1500회선까지 확장가능토록 설계되었다. SENTINEL-500은 중요한 부분을 이중화하여 고신뢰도를 갖도록 하였고 다수하이웨이의 채용과 동적 Time Slot 배정방식을 개발하여 거의 완전한 Non-Blocking switchng network를 구성 하였다. 또한 SENTINEL-500은 자체진단기능을 위시 하여 교환중단대 및 가입자를 위한 각종의service 기능을 갖고 있다.

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Sentinel lymph node mapping using tri-modal human serum albumin conjugated with visible dye, near infrared fluorescent dye and radioisotope

  • Kang, Se Hun;Kim, Seo-il;Jung, So-Youn;Lee, Seeyoun;Kim, Seok Won;Kim, Seok-ki
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.1 no.1
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    • pp.62-73
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    • 2015
  • We developed an evans blue-indocyanine green-$^{99m}Tc$-human serum albumin conjugate for sentinel lymph node mapping and we describe its unique potential usage for clinical implications. This conjugate has combined the strengths of visible blue dye, near-infrared fluorescence and radioisotope into one single conjugate without any additional weakness/disadvantage. All the components of evans blue-indocyanine green-$^{99m}Tc$-human serum albumin are safe and of low cost, and they have already been clinically used. This conjugate was stable in the serum, it showed a long retention time in the lymphatic system and the lymph nodes showed a much higher signal-to-noise ratio after the conjugate was injected intradermally into the paw of mice. Both the single-photon emission computed tomography and near-infrared fluorescent images of the mice were successfully obtained at the same time as the excised sentinel lymph nodes showed blue color. The visual color, near-infrared fluorescence and gamma ray from this agent could be complementary for each other in all the steps of sentinel lymph node sampling: exploring and planning sentinel lymph node before excision with visualization of the exact sentinel lymph node location during an operation. Therefore, the triple modal agent will possibly be very ideal for sentinel lymph node mapping because of the high signal-to-noise ratio for non-invasive imaging and its complementary multimodal nature, easy preparation and safety. It is promising for clinical applications and it may have great advantages over the traditional single modal methods.

Sentinel Lymph Node Navigation Surgery for Early Gastric Cancer: Is It a Safe Procedure in Countries with Non-Endemic Gastric Cancer Levels? A Preliminary Experience

  • Neto, Guilherme Pinto Bravo;Santos, Elizabeth Gomes Dos;Victer, Felipe Carvalho;Neves, Marcelo Soares;Pinto, Marcia Ferreira;Carvalho, Carlos Eduardo De Souza
    • Journal of Gastric Cancer
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    • v.16 no.1
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    • pp.14-20
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    • 2016
  • Purpose: Early diagnosis of gastric cancer is still the exception in Western countries. In the East, as in Japan and Korea, this disease is an endemic disorder. More conservative surgical procedures are frequently performed in early gastric cancer cases in these countries where sentinel lymph node navigation surgery is becoming a safe option for some patients. This study aims to evaluate preliminary outcomes of patients with early gastric cancer who underwent sentinel node navigation surgeries in Brazil, a country with non-endemic gastric cancer levels. Materials and Methods: From September 2008 to March 2014, 14 out of 205 gastric cancer patients underwent sentinel lymph node navigation surgeries, which were performed using intraoperative, endoscopic, and peritumoral injection of patent blue dye. Results: Antrectomies with Billroth I gastroduodenostomies were performed in seven patients with distal tumors. The other seven patients underwent wedge resections. Sentinel basin resections were performed in four patients, and lymphadenectomies were extended to stations 7, 8, and 9 in the other 10. Two patients received false-negative results from sentinel node biopsies, and one of those patients had micrometastasis. There was one postoperative death from liver failure in a cirrhotic patient. Another cirrhotic patient died after two years without recurrence of gastric cancer, also from liver failure. All other patients were followed-up for 13 to 79 months with no evidence of recurrence. Conclusions: Sentinel lymph node navigation surgery appears to be a safe procedure in a country with non-endemic levels of gastric cancer.

Current landscape and future perspective of sentinel node mapping in endometrial cancer

  • Bogani, Giorgio;Raspagliesi, Francesco;Maggiore, Umberto Leone Roberti;Mariani, Andrea
    • Journal of Gynecologic Oncology
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    • v.29 no.6
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    • pp.94.1-94.10
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    • 2018
  • Endometrial cancer (EC) represents the most common gynecological neoplasm in developed countries. Surgery is the mainstay of treatment for EC. Although EC is characterized by a high prevalence several features regarding its management are still unclear. In particular the execution of lymphadenectomy is controversial. The recent introduction of sentinel node mapping represents the mid-way between the execution and omission of node dissection in EC patients. In the present review we discuss the emerging role of sentinel node mapping in EC. In addition, we discussed how type of tracers utilized and site of injection impacted on sentinel node detection rates. Future perspective regarding EC management are also discussed.