• Childhood Kidney Diseases
• /
• v.19 no.2
• /
• pp.118-124
• /
• 2015

Purpose: The symptoms and signs of urinary tract infection (UTI) in early infancy are non-specific. Prompt diagnosis of UTI is important, as untreated UTI results in renal damage. Especially, febrile UTI in young infants coexist with other serious bacterial infections. The purpose this study was to propose modified Rochester criteria to differentiate viral infection from urinary tract infection. Methods: We carried out a retrospective investigation of 168 infants less than three months old with a tympanic temperature $>38^{\circ}C$ who were admitted to Chung-Ang University Hospital between 2011 and 2014. We compared the symptoms, physical examination results, and laboratory data between viral infection and UTI groups. A modified Rochester criterion was composed of statistically significant factors. Results: A total of 76 and 92 infants with UTI and a viral infection, respectively, were included. Statistically significant differences in gender, previous admission history, neutrophil ratio, and urine WBC count were found between the two study groups. Using a cut off value of 3 points, the sensitivity and specificity of the modified Rochester criteria were 71.28% and 78.57%, respectively. Conclusion: The modified Rochester criteria may give an outline for identifying young infants with UTI.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
• /
• v.25 no.8
• /
• pp.651-656
• /
• 2012

A study on capacitive characteristics of stylus pen for touch panel are progressed in this paper. Also the main factors for capacitive sensitivity are studied. Namely, highly sensitive stylus pen which can be applied to capacitive touch panel are studied based on the analysis of materials and process conditions regardless of pattern shapes. Stylus pen was made of PDMS(Poly-Di-Methyl-Siloxane) and conductive metal powders which does not damage the touch panel surface. We tried to get the advantages of both the properties of soft PDMS and conductive metal powders. We found that potential difference of capacitance change with conductivity of the composite materials(PDMS + metal powders) it implies that during touch process, large voltage difference can be caused by the high conductive materials of stylus pen. Stylus pen made by PDMS with mixed with Ag powders which has large conductivity shows more capacitance change of 1 pF than PDMS with other materials of Ni or C powders.

• Structural Engineering and Mechanics
• /
• v.64 no.1
• /
• pp.59-69
• /
• 2017

The field of fracture mechanics has gained significance because of its ability to address the behaviour of cracks. Predicting the fracture properties of concrete based on experimental investigations is a challenge considering the quasi-brittle nature of concrete. So, there is a need for developing a standard numerical tool which predicts the fracture energy of concrete which is at par with experimental results. The present study is an attempt to evaluate the fracture energy and characteristic length for different grades of concrete using Concrete Damage Plasticity (CDP) model. Indian Standard and EUROCODE are used for the basic input parameters of concrete. Numerical evaluation is done using Finite Element Analysis Software ABAQUS/CAE. Hsu & Hsu and Saenz stress-strain models are adopted for the current study. Mesh sensitivity analysis is also carried to study the influence of type and size of elements on the overall accuracy of the solution. Different input parameters like dilatation angle, eccentricity are varied and their effect on fracture properties is addressed. The results indicated that the fracture properties of concrete for various grades can be accurately predicted without laboratory tests using CDP model.

• Journal of Korean Society of Forest Science
• /
• v.99 no.6
• /
• pp.777-784
• /
• 2010

The purpose of this study was to develop evaluation indices for forest landscape classification. The indices were chosen to enable forest managers to establish effective landscape management strategies through three times of focus group interviews and email survey with experts. The 13 landscape evaluation indices were finally divided into four categories. They were ecological health (degree of green naturality, degree of ecological naturality, disease and insect damage, crown vitality), aesthetic visual quality (naturalness, harmony, diversity, traditionality, aesthetic appreciation, rarity), and sensitivity (level of tourism/recreational use), interruptions (damaged land, artificial structures). The five-level was suggested for the forest landscape classification system.

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.59 no.2
• /
• pp.369-373
• /
• 2010

Modem electronic circuits are of importance for the function of communication, traffic systems and security systems. An intentional threat to these systems could be of big casualties and economic disasters. This paper has shown damage effect of microcontroller device with coupling caused by UWB-HPEM(Ultra Wideband-High Power Electromagnetics). The UWB measurements were done at an Anechoic Chamber using a RADAN UWB voltage source, which can generate a transient impulse of about 180 kV. The susceptibility level for microcontroller has been assessed by effect of various operation line lengths. The results of susceptibility analysis has showed that the effect of the reset line length on the MT(Ma1function Threshold) is larger than the effect of the different line length(Data, Power, Clock). With the knowledge of these parameters electronic system can be designed exactly suitable concerning the system requirements. Based on the results, susceptibility of microcontroller can be applied to protection plan to elucidate the effects of microwaves on electronic equipment.

• Journal of Environmental Science International
• /
• v.5 no.1
• /
• pp.61-69
• /
• 1996

The combined wastewater of municipal landfill leachate and municipal sewage was treated using several sets of bench-scale aerated circulating system including porous media. Investigated items in this experiment were the dominant protozoa and metazoa in this system, the variation of microfauna relationship between operating condition and dominant genera. Also considered the factors determining dominant genera and their role. The outcome of this research is as follows; 1. Aspidisca, Vorticella, Truhellophyllum, Lecane, Philodina, Cyclops were mainly appeared prior to combinding leachate, while Trachelocerca, Bodo, Glaucoma were the dominant genera after combinding leachate. 2. As to metazoa, Nematode and Philodina were not influenced by 5oA leachate mixing ratio, meanwhile Crustacea has high sensitivity for increased leachate mixing ratio and it was not appeared in 5% leachate mixing ratio. 3. The appropriate treatability could'nt be expected at the above 10% leachate mixing ratio. Especially, in the condition of 20% leachate mixing ratio, all of the microfauna were affected damage seriously on their existence. Meanwhile hydraulic retention time, substrate loading rate and slut자e production rate didn't give notable influence on increasing the number of microfauna. 4. As to protozoa, saprozoic and holozoic species were appeared commonly and polysaprobic species were dominent. 5. Filamentous organsms were nearly not affected by leachate mixing. It seems that they could live without any trouble at the 10% leachate mixing ratio, if the substrate is sufficient. 6. Diversity of microfauna had a reducing trernd as the sewage was mixed with leachate.

• Mass Spectrometry Letters
• /
• v.13 no.4
• /
• pp.95-105
• /
• 2022

Amatoxin-induced mushroom poisoning starts with nonspecific symptoms of toxicity but hepatic damage may follow, resulting in the rapid development of liver insufficiency and, ultimately, coma and death. Accurate detection of amatoxins, such as α-, β-, and γ-amanitin, within the first few hours after presentation is necessary to improve the therapeutic outcomes of patients. Therefore, analytical methods for the identification and quantification of α-, β-, and γ-amanitin in biological samples are necessary for clinical and forensic toxicology. This study presents a literature review of the analytical techniques available for amatoxin detection in biological matrices, and established an inventory of liquid chromatography (LC) techniques with mass spectrometry (MS), ultraviolet (UV) detection, and electrochemical detection (ECD). LC-MS methods using quadrupole tandem mass spectrometry, time-of-flight mass spectrometry, and orbitrap MS are powerful analytical techniques for the identification and determination of amatoxins in plasma, urine, serum, and tissue samples, with high sensitivity, specificity, and reproducibility compared to LC with UV and ECD, enzyme-linked immunoassay, and capillary electrophoresis methods.

• Nuclear Engineering and Technology
• /
• v.56 no.7
• /
• pp.2859-2874
• /
• 2024

This paper presents the finite element deformation and failure simulation of a typical Korean high-power reactor vessel under a severe accident characterized by large break loss of coolant (LBLOCA) with in-vessel retention of molten corium through external reactor vessel cooling (IVR-ERVC) conditions. Temperature distributions calculated using Modular Accident Analysis Program Version 5 (MAAP5) as thermal boundary conditions were used, and ABAQUS thermal and structural analyses were performed. After full ablation, the temperature of the inner surface in the thinnest section remained high (920 ℃), but the stress remained relatively low (less than 6 MPa). At the outer surface, the stress was as high as 250 MPa; however, the resulting plastic strain was small owing to the low temperature of 200 ℃. Variations in stress, inelastic strain, and temperature with time in the thinnest section suggest that the plastic and creep strains are saturated owing to stress relaxation, resulting in low cumulative damage. Thus, the lower head of the vessel can maintain its structural integrity under LBLOCA with IVR-ERVC conditions. The sensitivity analysis of internal pressure indicates the occurrence of failure in the thinnest section at an internal pressure >9.6 MPa via local necking followed by failure due to high stresses.

• International Journal of Highway Engineering
• /
• v.13 no.4
• /
• pp.103-115
• /
• 2011

Concrete slab curls and warps due to the uneven distribution of temperature and moisture and as the result, internal stress develops within the slab. Therefore, environmental loads must be considered in addition to the traffic loads to predict the lifespan of the concrete pavement more accurately. The strength of the concrete slab is gradually decreases to a certain level at which fatigue cracking is generated by the repetitive traffic and environmental loadings. In this study, a new fatigue regression model was developed based on the results from previously performed studies. To verify the model, another laboratory flexural fatigue test program which was not used in the model development, was conducted and compared with the predictions of other existing models. Each fatigue model was applied to analysis logic of cumulative fatigue damage of concrete pavement developed in the study. The sensitivity of cumulative fatigue damage calculated by each model was analyzed for the design factors such as slab thickness, joint spacing, complex modulus of subgrade reaction and the load transfer at joints. As the result, the model developed in this study could reflect environmental loading more reasonably by improving other existing models which consider R, minimum/maximum stress ratio.

• Journal of Microbiology and Biotechnology
• /
• v.27 no.3
• /
• pp.633-643
• /
• 2017

To examine the pro-apoptotic role of the human ortholog (YPEL5) of the Drosophila Yippee protein, the cell viability of Saccharomyces cerevisiae mutant strain with deleted MOH1, the yeast ortholog, was compared with that of the wild-type (WT)-MOH1 strain after exposure to different apoptogenic stimulants, including UV irradiation, methyl methanesulfonate (MMS), camptothecin (CPT), heat shock, and hyperosmotic shock. The $moh1{\Delta}$ mutant exhibited enhanced cell viability compared with the WT-MOH1 strain when treated with lethal UV irradiation, 1.8 mM MMS, $100{\mu}M$ CPT, heat shock at $50^{\circ}C$, or 1.2 M KCl. At the same time, the level of Moh1 protein was commonly up-regulated in the WT-MOH1 strain as was that of Ynk1 protein, which is known as a marker for DNA damage. Although the enhanced UV resistance of the $moh1{\Delta}$ mutant largely disappeared following transformation with the yeast MOH1 gene or one of the human YPEL1-YPEL5 genes, the transformant bearing pYES2-YPEL5 was more sensitive to lethal UV irradiation and its UV sensitivity was similar to that of the WT-MOH1 strain. Under these conditions, the UV irradiation-induced apoptotic events, such as FITC-Annexin V stainability, mitochondrial membrane potential (${\Delta}{\psi}m$) loss, and metacaspase activation, occurred to a much lesser extent in the $moh1{\Delta}$ mutant compared with the WT-MOH1 strain and the mutant strain bearing pYES2-MOH1 or pYES2-YPEL5. These results demonstrate the functional conservation between yeast Moh1 and human YPEL5, and their involvement in mitochondria-dependent apoptosis induced by DNA damage.