• 제목/요약/키워드: sensitivity to damage

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A couple Voronoi-RBSM modeling strategy for RC structures

  • Binbin Gong;Hao Li
    • Structural Engineering and Mechanics
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    • v.91 no.3
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    • pp.239-250
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    • 2024
  • With the aim to provide better predication about fracture behavior, a numerical simulating strategy based on the rigid spring model is proposed for reinforced concrete (RC) structures in this study. According to the proposed strategy, concrete is partitioned into a series of irregular rigid blocks based on the Voronoi diagram, which are connected by interface springs. Steel bars are simulated by bar elements, and the bond slip element is defined at bar element nodes to describe the interaction between reinforcement and concrete. A concrete damage evolution model based on the separation criterion is adopted to describe the weakening process of interface spring between adjacent blocks, while a nonlinear bond slip model is introduced to simulate the synergy behaviour of reinforced steel bars and concrete. In the damage evolution model of concrete, the influence of compressive stress perpendicular to the interface on the shear strength is considered. To check the effectiveness and applicability of the proposed modelling, experimental and numerical studies about a simply-supported RC beam and the two-notched concrete plates in Nooru-Mohamed's experiment are conducted, and the grid sensitivity are investigated.

Exploitation of the Dose/Time-Response Relationship for a New Measure of DNA Repari in the Single-Cell Gel Electrophoresis (Comet) Assay

  • Kim, Byung-Soo;Edler, Lutz;Park, Jin-Joo;Fournier, Dietrich Von;Haase, Wulf;Sautter-Bihl, Mare-Luise;Hagmuller, Egbert;Gotzes, Florian;Thielmann, Heinz Walter
    • Toxicological Research
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    • v.20 no.2
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    • pp.89-100
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    • 2004
  • The comet assay (also called the single-cell gel electrophoresis assay) has been widely used for detecting DNA damage and repair in individual cells. Since the conventional methods of evaluating comet assay data using frequency statistics are unsatisfactory we developed a new quantitative measure of DNA damage/repair that is based on all information residing in the dose/time-response curves of a comet experiment. Blood samples were taken from 25 breast cancer patients before undergoing radiotherapy. The comet assay was performed under alkaline conditions using isolated lymphocytes. Tail DNA, tail length, tail moment and tail inertia of the comet were measured for each patient at four doses of $\gamma$-rays (0, 2, 4 and 8 Gy) and at four time points after irradiation (0, 10, 20 and 30 min) using 100 cells each. The resulting three-dimensional dose-time response surface was modeled by multiple regression, and the second derivative, termed 2D, on dose and time was determined. A software module was programmed in SAS/AF to compute 2D values. We applied the new method successfully to data obtained from cancer patients to be assessed for their radiation sensitivity. We computed the 2D values for the four damage measures, i.e., tail moment, tail length, tail DNA and tail inertia, and examined the pairwise correlation coefficients of 2D both on the log scale and the unlogged scale. 2D values based on tail moment and tail DNA showed a high correlation and, therefore, these two damage measures can be used interchangeably as far as DNA repair is concerned. 2D values based on tail inertia have a correlation profile different from the other 2D values which may reflect different facets of DNA damage/repair. Using the dose-time response surface, other statistical models, e.g., the proportional hazards model, become applicable for data analysis. The 2D approach can be applied to all DNA repair measures, Le., tail moment, tail length, tail DNA and tail inertia, and appears to be superior to conventional evaluation methods as it integrates all data of the dose/time-response curves of a comet assay.

Practicalities of structural health monitoring

  • Shrive, P.L.;Brown, T.G.;Shrive, N.G.
    • Smart Structures and Systems
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    • v.5 no.4
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    • pp.357-367
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    • 2009
  • Structural Health Monitoring (SHM), particularly remote monitoring, is an emerging field with great potential to help infrastructure owners obtain more and up-to-date knowledge of their structures. The methodology could provide supplemental information to guide the frequency and extent of visual inspections, and the possible need for maintenance. The instrumentation for a SHM system needs to be developed with longevity and the objectives for the system in mind. Sensors need to be selected for reliability and durability, sited where they provide the maximum information for the objectives, and where they can be accessed and replaced should the need arise over the monitoring period. With the rapid changes now occurring with sensors and software, flexibility needs to be in place to allow the system to be upgraded over time. Damage detection needs to be considered in terms of the type of damage that needs to be detected, informing maintenance requirements, and how detection can be achieved. Current vibration analysis techniques appear not yet to have achieved the necessary sensitivity for that purpose. Societal factors will influence the design of a SHM system in terms of the sophistication of the instrumentation and methodology employed.

Evaluation of DNA Damage and Repair Kinetics in the Earthworm (Eisenia fetida) Exposed to Radiation and Mercury (방사선과 수은에 의해 유도된 Eisenia fetida 체강세포의 DNA 손상 및 수복 평가)

  • Ryu, Tae-Ho;Nili, Mohammad;An, Kwang-Guk;Kim, Jin-Kyu
    • Korean Journal of Environmental Biology
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    • v.29 no.1
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    • pp.68-73
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    • 2011
  • The single cell gel electrophoresis (SCGE) assay is a microelectrophoretic technique for assessments of DNA damage at the level of the individual eukaryotic cell. The SCGE assay, due to its simplicity, sensitivity and need of a few cells, has advantages compared to other genomic damage assays such as sister chromatid exchange, chromosomal aberration and micronucleus test. In this study, investigated were the levels of DNA damage and the repair kinetics in the coelomocytes of Eisenia fetida treated with HgCl2 and ionizing radiation by means of the SCGE assay. For detecting DNA damage and repair in coelomocytes, earthworms (E. fetida) were irradiated with six doses of ${\gamma}$-rays (0, 2.5, 5, 10, 20 and 50 Gy) and in vivo exposed to mercuric chloride at 0, 80 and 160 mg $kg^{-1}$ for 48 hours. Then the Olive tail moments were measured during 0~12 hours after irradiation and 0~72 hours after Hg treatment. The results showed that the more the oxidative stress was induced by mercury and radiation, the longer the repair time was required. Also, the results suggest that the SCGE assay may be used as an important tool for comparison of the sensitivity of different species to oxidative stresses.

Damage Detection in Complex Structures using Pattern Recognition of Modal Sensitivity (모드민감도 패턴인식에 의한 복잡한 구조물의 손상발견)

  • 김정태;류연선;노리스스텁스
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 1997.04a
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    • pp.97-105
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    • 1997
  • A methodology to identify a baseline modal model of a complicated 3-D structure using limited structural and modal information is experimentally examined. In the first part, a system's identification theory for the methodology to identify, baseline modal responses of the structure is outlined. Next, an algorithm is designed to build a generic finite element model of the baseline structure and to calibrate the model by using only a set of post-damage modal parameters. In the second part, the feasibility of the methodology is examined experimentally using a field-tested truss bridge far which only post-damaged modal responses were measured for a few vibration modes. For the complex 3-D bridge with many members, we analyzed to identify unknown stiffness parameters of the structure by using modal parameters of the initial two modes of vibration.

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Damage identification of belt conveyor support structure using periodic and isolated local vibration modes

  • Hornarbakhsh, Amin;Nagayama, Tomonori;Rana, Shohel;Tominaga, Tomonori;Hisazumi, Kazumasa;Kanno, Ryoichi
    • Smart Structures and Systems
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    • v.15 no.3
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    • pp.787-806
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    • 2015
  • Due to corrosion, a large number of belt conveyors support structure in industrial plants have deteriorated. Severe corrosion may result in collapse of the structures. Therefore, practical and effective structural assessment techniques are needed. In this paper, damage identification methods based on two specific local vibration modes, named periodic and isolated local vibration modes, are proposed. The identification methods utilize the facts that support structures have many identical members repeated along the belt conveyor and there exist some local modes within a small frequency range where vibrations of these identical members are much larger than those of the other members. When one of these identical members is damaged, this member no longer vibrates in those modes. Instead, the member vibrates alone in an isolated mode with a lower frequency. A damage identification method based on frequencies comparison of these vibration modes and another method based on amplitude comparison of the periodic local vibration mode are explained. These methods do not require the baseline measurement records of undamaged structure. The methods is capable of detecting multiple damages simultaneously. The applicability of the methods is experimentally validated with a laboratory model and a real belt-conveyor support structure.

Transmission of ultrasonic guided wave for damage detection in welded steel plate structures

  • Liu, Xinpei;Uy, Brian;Mukherjee, Abhijit
    • Steel and Composite Structures
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    • v.33 no.3
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    • pp.445-461
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    • 2019
  • The ultrasonic guided wave-based technique has become one of the most promising methods in non-destructive evaluation and structural health monitoring, because of its advantages of large area inspection, evaluating inaccessible areas on the structure and high sensitivity to small damage. To further advance the development of damage detection technologies using ultrasonic guided waves for the inspection of welded components in structures, the transmission characteristics of the ultrasonic guided waves propagating through welded joints with various types of defects or damage in steel plates are studied and presented in this paper. A three-dimensional (3D) finite element (FE) model considering the different material properties of the mild steel, high strength steel and austenitic stainless steel plates and their corresponding welded joints as well as the interaction condition of the steel plate and welded joint, is developed. The FE model is validated against analytical solutions and experimental results reported in the literature and is demonstrated to be capable of providing a reliable prediction on the features of ultrasonic guided wave propagating through steel plates with welded joints and interacting with defects. Mode conversion and scattering analysis of guided waves transmitted through the different types of weld defects in steel plates are performed by using the validated FE model. Parametric studies are undertaken to elucidate the effects of several basic parameters for various types of weld defects on the transmission performance of guided waves. The findings of this research can provide a better understanding of the transmission behaviour of ultrasonic guided waves propagating through welded joints with defects. The method could be used for improving the performance of guided wave damage detection methods.

Diagnostic Significance of Neonatal Electroencephalography (신생아 뇌파의 진단적 유용성에 대한 연구)

  • Kim, Byeong Eui;Kim, Heung Dong
    • Clinical and Experimental Pediatrics
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    • v.46 no.2
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    • pp.137-142
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    • 2003
  • Purpose : This study was performed to determine the sensitivity of neonatal electroencephalography (EEG) in detecting underlying brain disease, to compare the sensitivity and specificity of EEG with those of brain ultrasonography and to determine the prognostic value of EEG for neonatal neurologic diseases. Methods : Eighty-seven newborn babies were subjected to a electroencephalographic examination for the evaluation of underlying neurological diseases and EEGs were recorded at least before three days of life. The findings of early ultrasonography performed within three days after birth were compared with those of magnetic resonance imaging(MRI) or ultrasonography after seven days of life. Results : The EEG results were more sensitive and specific than ultrasonography for the detection of neonatal brain damage. The EEG results showed 91.7% sensitivity for mild grade neurological sequelae and 100.0% sensitivity for moderate and severe-grade neurological sequelae in predicting the neurological outcome. However, early ultrasonography results showed 20.8% and 18.8% of sensitivity and specificity, respectively. Conclusion : EEG is a highly sensitive diagnostic tool for detecting neonatal brain disease and is valuable for predicting the long-term outcome of neurologic sequelae.

Priority Rankings of the System Modifications to Reduce Core Damage Frequency of Wolsong NPP Units 2/3/4

  • Kwon, Jong-Jooh;Kim, Myung-Ki;Seo, Mi-Ro;Hong, Sung-Yull
    • Proceedings of the Korean Nuclear Society Conference
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    • 1998.05a
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    • pp.899-905
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    • 1998
  • The analysis priority makings the recommendation to reduce the total core damage frequency (CDF) of Wolsong nuclear Power Plant nits 2/3/4 was Performed in this paper. In order to derive the recommendation, the sensitivity analysis of CDF on which major contributors effect m performed based on the accident quantification results during Level 1 Probabilistic safety assessment (PSA). Priorities were ranked in tile way that compares the CDF reduction rate with efforts required to implement those recommendations using risk matrix

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Real-time Failure Detection of Composite Structures Using Optical Fiber Sensors (광섬유 센서를 이용한 복합재 구조물의 실시간 파손감지)

  • 방형준;강현규;류치영;김대현;강동훈;홍창선;김천곤
    • Proceedings of the Korean Society For Composite Materials Conference
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    • 2000.11a
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    • pp.128-133
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    • 2000
  • The objective of this research is to develop real-time failure detection techniques for damage assessment of composite materials using optical fiber sensors. Signals from matrix cracking or fiber fracture in composite laminates are treated by signal processing unit in real-time. This paper describes the implementation of time-frequency analysis such as the Short Time Fourier Transform(STFT) to determine the time of occurrence of failure. In order to verify the performance of the optical fiber sensor for stress wave detection, we performed pencil break test with EFPI sensor and compared it with that of PZT. The EFPI sensor was embedded in composite beam to sense the failure signals and a tensile test was performed. The signals of the fiber optic sensor when damage occurred were characterized using STFT and wavelet transform. Failure detection system detected the moment of failure accurately and showed good sensitivity with the infinitesimal failure signal.

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