• Title/Summary/Keyword: sensitive period

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The variation of serological titers on the chickens infected pullorum disease from Kyongbuk provinces (경북지방유래 추백리 양성계에서의 균분리 및 혈청역가 추이)

  • 김영환;김경희;우용구;장영술;조민희;김수웅
    • Korean Journal of Veterinary Service
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    • v.20 no.1
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    • pp.19-26
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    • 1997
  • The present study was conducted to investigate the general epidemiological situations with 18-pullorum infected chickens from Kyongbuk provinces during the period from June 1995 to January 1996. On the Salmonella pullorum isolation tests by rectal swab culture method from infected chickens (386-samples), any Salmonella spp was not isolated from infected live-birds. But 2-S pullorum were isolated of 2-dead chickens(33.3% ) from 6-dead chickens which were positively reacted by serological tests. On the other hand, we could not isolated any Salmonella spp. in any parts of egg-contents ; egg-shell, egg-white and egg-yolks with 25-infected bird eggs. On the tests of antibiogram, 2-S pullorum strains were highly sensitive to GM, AM, SXT, CZ, K, FIM, ENR, C, AN, N, NN, LIN+SP, CF, TE and PB, respectively and intermediate sensitive to the CB, CFP, CL, S, P and XNL. But 2-strains were resistant to CC, DP, E, L, OX, TLA and TyLO. In the serological tests, pullorum antibody titers of 18-infected birds was from 2.76 to 9.18 with average by the microplate test. During the 6-months, pullorum antibody average titers were not changed generally. To validate the effects of the antimicrobial agent treatments to the serological antibody titers, infected 6-chickens was medicated with 0.5%-futazolidone. The titer of premeditated birds was average 4.26 but after medication with furazolidone, the titers of treated 6-birds was average 4.08.

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Two Pediatric Patients with Herbal Medicine-Induced Nephrotic Syndrome

  • Yang, Sohyoung;Oh, Arum;Ha, Tae-Sun
    • Childhood Kidney Diseases
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    • v.19 no.2
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    • pp.171-175
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    • 2015
  • Nephrotic syndrome (NS) is a common chronic disease in children; in 90 percent of cases, the condition is primary (idiopathic). Toxic nephropathy can be induced by herbal medicines, and is mainly manifested as tubulointerstitial nephritis and rarely, as glomerulopathy. Here in, we describe two cases of steroid-sensitive NS, which developed after the patients received herbal medicines. A 5-year-old boy and an 8-year-old girl were separately admitted within a short time period with acute onset of generalized edema, proteinuria, hypoalbuminemia, and hypercholesterolemia. Each patient had previously taken herbal medicine, which had been prescribed by different oriental medical clinics for different conditions. The patients were diagnosed with herbal medicine-induced NS and were treated empirically by a standard steroid therapy, with subsequent resolution of their NS. One patient relapsed, but her NS again responded to steroid therapy. We described two unusual cases of prototypical pediatric, steroid-sensitive NS, which was presumed to be minimal-change disease that developed after the administration of herbal medicines. We also reviewed the literature.

Formulation and In vitro Evaluation of Transdermal Drug Delivery System for Galantamine

  • Hossain, Md. Kamal;Subedi, Robhash Kusam;Chun, Myung-Kwan;Kim, Eun-Jung;Moon, Hwan-Shik;Choi, Hoo-Kyun
    • Journal of Pharmaceutical Investigation
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    • v.41 no.1
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    • pp.1-7
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    • 2011
  • The effects of different formulation variables including pressure sensitive adhesive (PSA), permeation enhancer, thickness of the matrix and loading amount of drug on the transdermal absorption of galantamine were investigated across the hairless mouse skin. The permeation profile of galantamine was different depending on the types of PSA, loading amount of drug, thickness of the matrix and type of enhancer used. Highest flux of galantamine was obtained from acrylic PSA but crystals were formed in the patch within 72 h. Among the PSAs screened, crystal formation was not observed only in the patches formulated in Styrene Butadiene Styrene (SBS) matrix. Permeation rate increased linearly as the concentration of galantamine in SBS matrix increased from 2.5 to 15% w/w. Among the enhancers screened, Brij$^{(R)}$ 30 provided highest flux of galantamine. Matrix thickness of 80 ${\mu}m$ was optimum for maintaining adhesiveness as well as consistently delivering galantamine for longer period of time.

A Study on Optimization of Thermophysiological Indices for Harbor Workers in Summer: Improvement of MENEX Model's Input Data Considering the Work Environment (하계 항만열환경지수 최적화 방안연구: 항만작업환경을 반영한 MENEX모델의 입력변수 개선)

  • Yun, Jinah;Hwang, Mi-Kyoung;Kim, Yoo-Keun
    • Journal of Environmental Science International
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    • v.25 no.7
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    • pp.951-961
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    • 2016
  • To prevent increasing instances of heat-related illnesses due to heat waves generated by climate change, a customized thermal environment index should be developed for outdoor workers. In this study, we conducted sensitivity analysis of the Masan harbor during a heat wave period (August 9th to 15th, 2013) using the MENEX model with metabolic rate and clothing-insulation data, in order to obtain realistic information about the thermal environment. This study shows that accurate input data are essential to gather information for thermophysiological indices (PST, DhR, and OhR). PST is sensitive to clothing insulation as a function of clothing. OhR is more sensitive to clothing insulation during the day and to the metabolic rate at night. From these results, it appears that when exposed to high-temperature thermal environments in summer, wearing highly insulated clothing and getting enough rest (to lower the metabolic rate) can aid in preventing heat-related illnesses. Moreover, in the case of high-intensity harbor work, quantification of allowed working time (OhR) during heat waves is significant for human health sciences.

Declining Fixed Investment and Increasing Financial Investment of Korean Corporations

  • Kim, Daehwan;Kwon, Sunhee;Ryou, Jai-Won
    • East Asian Economic Review
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    • v.23 no.4
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    • pp.353-379
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    • 2019
  • This paper aims to determine factors causing the stagnation of Korean firms' fixed investment after the global financial crisis, using panel data for the period of 1999-2016. Fixed investment remained sensitive to cash flow and Tobin's q although their effects decreased after the global financial crisis. A decreasing trend of cash flow and an increase in Tobin's q since the early 2000's imply that the worsening cash flow was a major factor behind the sluggish investment after the crisis. Meanwhile, debt-equity ratio remained significant for non-chaebol affiliated firms, reflecting disparity in access to external financing. Volatility of stock returns also became insignificant after the crisis, casting doubt on the argument that uncertainty was a major factor contributing to the decline of fixed investment. Analysis of financial investment confirmed the significant effect of cash flow, larger than that on financial investment than on fixed investment. In particular, debt repayment and other financial investment, except share repurchase, were sensitive to cash flow. However, the substitution of fixed investment by financial investment is a consequence, rather than a cause of declining fixed investment.

The Impact of Medicaid Expansion to include population with low income on the preventable hospitalizations (의료급여 수급권자 확대정책이 예방가능한 입원율에 미친 영향)

  • Shin, Hyun-Chul;Kim, Se-Ra
    • Health Policy and Management
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    • v.20 no.1
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    • pp.87-102
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    • 2010
  • The objective of this study were to examine the impact of medicaid coverage expansion policy aimed at improving access to primary care. The case-control study was conducted to compare preventable hospitalization(PH) rate in new medicaid recipients versus national health insurance(NHI) enrollees form 1996 to 2001. Rates of preventable hospitalization associated with ambulatory care sensitive conditions(ACSC) were calculated and standardized by age and sex. Multinomial logit regression model was used to control the confounding factors such as age, gender and charlson comorbidity index Annual PH rates in the new medicaid increased 1.64 times after medicaid expansion, with controling confounding factors. Meanwhile, annual PH rate in the NHI increased 1.68 times during the same period, with adjusting confounding factors. Current findings suggest that the new medicaid PH rate was less likely to rise than NHI PH rate after implementing medicaid expansion. This study is expected to provide policy-relevant evidence of medicaid expansion to include population with low income.

A Survey on the interruption costs for the sensitive industrial customers to the short duration interruption (순간정전에 민감한 산업수용가의 정전비용에 관한 조사연구)

  • Nam, Kee-Young;Choi, Sang-Bong;Ryoo, Hee-Suk;Lee, Jae-Duck;Jeong, Seong-Hwan;Kim, Dae-Kyung
    • Proceedings of the KIEE Conference
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    • 2005.07a
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    • pp.90-92
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    • 2005
  • This paper addresses the analysis of interruption costs and the studies made through the direct interview with Korean Industrial customers for the period of two years. It is conducted to evaluate the direct and short duration interruption costs resulting from local random electrical supply interruptions. The cost is evaluated by providing a designed questionnaire focused on the experience or the preparative actions which consumers predicted they would take. In the first phase, authors made a survey on all types of industry with 176 industrial customers and evaluated them as per standard industry classification (SIC). In that case, the evaluation data obtained are not so reasonable, because the number of sampled industries was small and the sampled industries were surveyed by being divided into 18 types. So, in the second phase the authors concentrated on only 4 types of 302 industries who have many and large sensitive loads to the short duration interruption.

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A survey on the incidence rate of foot diseases in dairy cattle

  • Lee, Cheong-San;Ryu, Dae-Yeol;Kwak, Hak-Koo;Hyun, Gong-Yul;Park, Kyung-Jae;Cho, Woo-Young;Lee, Jong-In
    • Korean Journal of Veterinary Service
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    • v.24 no.4
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    • pp.347-352
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    • 2001
  • This study was carried out to investigate the status of hoof diseases and to develope treatment method for cattle with hoof diseases during the period of January to December in 2000. Out of 435 heads, 34 heads(7.8%) had hoof diseases. In respect to season, incidence rate was higher in August to September than that of other seasons. The incidence rates of hoof rot, pododermatitis verrucosae, laminitis, other cases and trauma were 14 cases(41%), 10 cases (29%), 7 cases(21%), 2 cases(6%) and 1 case(3%), respectively. In respect to age and milk production, Incidence rate was higher in the cattle with high milk production. Incidence rate of hoof diseases on the hind-limbs was higher than that of the fore-limbs. E. coli(8 strains), Clostridium spp(8 strains), Staphylococcus spp(6 strains), Fusobacterium spp(6 strains), and Bacteroides spp(6 strains) were isolated from the hoof lesions. All isolates were sensitive to composite preparation made of mainly formalin with picric acid and phenol. (Treatment against each strains isolated was sensitive to composite preparation made out of the main constitutions of formalin with picric acid and phenol).

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Analysis of Construction Cost Fluctuation Trends and Features on Apartment Housing

  • Park, Wonyoung;Kang, Tai-Kyung;Baek, Seung-Ho;Lee, Yoo-Sub
    • Journal of the Korea Institute of Building Construction
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    • v.12 no.6
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    • pp.624-635
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    • 2012
  • Construction projects, including housing, are carried out over long periods of time. According to changes to the construction period, the cost of input materials and wages also changes. Therefore appropriate management is important in order to minimize cost risks caused by fluctuations in prices. In Korea, housing units are usually sold in lots prior to construction completion. Therefore, careful management of input elements such as materials and equipment that are sensitive to price fluctuations is very important. This study deals with how the price fluctuation of materials, labor, and equipment influences the change of housing cost and seeks a way for cost management through identifying key resources sensitive to price fluctuation. As a result, a change to the housing cost index multiplies depending on cost changes of materials and labor together. Labor costs are a major factor on the housing cost index. In addition, certain types of materials and labor input to housing construction greatly influence price fluctuations. Thus, it is found that managing those main cost factors is the key for effective cost management.

Design of Energy Efficient MAC Protocol for Delay Sensitive Application over Wireless Sensor Network (무선 센서 네트워크상에서 시간지연에 민감한 데이터 전송을 위한 에너지 효율적인 MAC 프로토콜 설계)

  • Oh, Hyung-Rai;Song, Hwang-Jun
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.34 no.11B
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    • pp.1169-1177
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    • 2009
  • This paper presents an energy efficient MAC protocol for delay-sensitive data transmission over wireless sensor network. In general, energy consumption and delay depend on Channel Monitoring Interval and data sensing period at each sensor node. Based on this fact, we propose a new preamble structure to effectively advertise Channel Monitoring Interval and avoid the overhearing problem. In order to pursue an effective tradeoff between energy consumption and delay, we also develop a Channel Monitoring Interval determining algorithm that searches for a sub-optimal solution with a low computational complexity. Finally, experimental results are provided to compare the proposed MAC protocol with existing sensor MAC protocols.