• Journal of Life Science
• /
• v.31 no.2
• /
• pp.192-198
• /
• 2021

Red yeast rice has been extensively used as food and traditional medicine for thousands of years in East Asian countries. It is produced by the fermentation of a particular yeast (in general, Monascus purpureus) as rice and various cereals (barley, soybean, etc.). Monascus sp. produces many secondary metabolites during its growth, including pigments, monacolins, and γ-aminobutyric acid. Some metabolites―specifically, monacolin K, γ-aminobutyric acid, dimerumic acid, and monascus pigments―have been reported to lower cholesterol and blood pressure while showing anti-obesity effects. In this study, we investigated the anti-obesity effect of ethanol extract from red yeast barley (RYB) fermented with Monascus sp. BHN-MK 2 on 3T3-L1 cells. The anti-obesity effects of RYB extract were examined: its lipid accumulation inhibitory effect was tested by Oil Red O staining, and obesity-related mRNA expression levels were tested by real-time RT-PCR in MDI stimulated 3T3-L1 cells. The intracellular lipid content of MDI-stimulated 3T3-L1 cells decreased significantly to 5.04%, 12.24%, and 23.52% in response to 200, 400, and 800 ㎍/ml RYB, respectively. Moreovers, we evaluated that RYB extract significantly downregulated the expression of C/EBPα, SREBP-1, and PPAR-γ gene in a dose-dependent manner. As a result, red yeast barley ethanol extracts exerted the strongest anti-obesity effects. Also, the results indicate that red yeast barley could be used as a functional anti-obesity food material.

• Journal of Industrial Convergence
• /
• v.20 no.6
• /
• pp.27-35
• /
• 2022

The purpose of this study is to analyze the metaverse-related issues in the news big data from an educational perspective, explore their characteristics, and provide implications for the educational applicability of the metaverse and future education. To this end, 41,366 cases of metaverse-related data searched on portal sites were collected, and weight values of all extracted keywords were calculated and ranked using TF-IDF, a representative term weight model, and then word cloud visualization analysis was performed. In addition, major topics were analyzed using topic modeling(LDA), a sophisticated probability-based text mining technique. As a result of the study, topics such as platform industry, future talent, and extension in technology were derived as core issues of the metaverse from an educational perspective. In addition, as a result of performing secondary data analysis under three key themes of technology, job, and education, it was found that metaverse has issues related to education platform innovation, future job innovation, and future competency innovation in future education. This study is meaningful in that it analyzes a vast amount of news big data in stages to draw issues from an education perspective and provide implications for future education.

• English Language & Literature Teaching
• /
• v.11 no.4
• /
• pp.287-304
• /
• 2005

Since Air and Correspondence High School (ACHS) in Korea was established in 1974, it has been serving many people who couldn't take the opportunities for learning in the regular high school due to several reasons. Regardless of the rapid change in technologies and educational needs during the past 31 years, however, ACHS hasn't changed much. Concerns have been recently made about the validity of the unchanged school system and many issues have been discussed relating to the innovation of the school system. Focusing on the teaching and learning contents, one of the important issues with respect to the school system, this paper examines the 7th English Curriculum for ACHS. The paper also investigates the textbooks used in ACHS to see how closely they align with the students' English proficiency and ACHS' instructional method by employing McDonough and Shaw's(1993) framework for textbook analysis. The results revealed that the current curriculum does not sufficiently reflect ACHS's characteristics, which leads to the adoption and development of inappropriate textbooks in terms of overall coherence, proficiency level, etc. The results suggest that the development of the curriculum and textbooks for ACHS should be based upon the students' needs and their level of proficiency rather than depending on the national curriculum and government-authorized textbooks intended for the relatively homogeneous school-age learners.

• Journal of Distribution Research
• /
• v.8 no.2
• /
• pp.85-101
• /
• 2003

The purpose of this study is to identify the factors that influence the decision of participation in B2B E -marketplaces and explain the nature of their influence on the decision. Using survey data from 135 senior managers in business-to-business firms, the authors analyzed factors affecting the participation intention of e-marketplaces. We found that expected benefits, switching costs, the primary task environment, the secondary task environment, the macro environment, technological opportunism and complimentary asset have a significant relationship with the intention of participation in E-marketplaces. Finally, we discuss several theoretical and practical implications, and suggest limitations for the research and future research issue.

• The Journal of Information Technology
• /
• v.7 no.4
• /
• pp.9-20
• /
• 2004

Result Dos that materialization KNU Virus Wall to solve serious problem Hurtfulness Virus is present network chiefly in this research to do not become and do correct disposal in situation such as internet and Multiple Protocol that is done intelligence anger for ESM, CIS and MIS side as secondary to solve this problem about out log analysis system embody. As a result, could use comprehensively, and can click by Site Design, Packet transmission, and used to interior internet (GroupWare) in information protection aspect because intelligence enemy to face each other ESM's various hacking and virus uses Enterprise Security Management system and CIS, whole web through Smart View and relation of security could do monitoring.

• CELLMED
• /
• v.4 no.3
• /
• pp.15.1-15.14
• /
• 2014

Andrographis paniculata (Burm. F.) Wall. Ex Nees (Family: Anthaceae) is a traditionally known Ayurvedic medicinal plant. Several well-controlled clinical trials conducted during recent years have consistently reconfirmed that Andrographis paniculata extracts are effective in suppressing cardinal symptoms of diverse inflammatory and infectious diseases. Despite extensive efforts though, many questions concerning bioactive constituents of such extracts and their modes of actions still remain unanswered. Amongst diverse diterpene lactones isolated to date from such extracts, andrographolide is often considered to be the major, representative, or bioactive secondary metabolite of the plant. Therefore, it has attracted considerable attention of several drug discovery laboratories as a lead molecule potentially useful for identifying structurally and functionally novel drug. Critical analysis of available preclinical and clinical information on Andrographis paniculata extracts and pure andrographolide strongly suggest that they are pharmacologically polyvalent and that they possess adaptogenic properties. Aim of this communication is to summarize and critically analyze such data, and to point out some possibilities for more rationally exploiting their adaptogenic properties for discovering novel therapeutic leads, or for obtaining pharmacologically better standardized phyto-pharmaceuticals.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
• /
• v.22 no.7
• /
• pp.7-15
• /
• 2008

A single active capacitor snubber-assisted soft-switching sinewave pulse modulation utility-interactive power conditioner with a three-winding flyback high frequency transformer link and a bidirectional active power switch in its secondary side has been proposed. With the aid of the switched-capacitor quasi-resonant snubber cell, the high frequency switching devices in the primary side of the proposed DC-to-AC sinewave power inverter can be turned-off with ZVS commutation. In addition to this, the proposed power conditioner in the DCM can effectively take the advantages of ZCS turn-on commutation. Its output port is connected directly to the utility AC power source grid. At the end, the prototype of the proposed HF-UPC is built and tested in experiment. Its power conversion conditioning and processing circuit with a high frequency flyback transformer link is verified and the output sinewave current is qualified in accordance with the power quality guidelines of the utility AC interactive power systems.

• The Journal of Korean Association of Computer Education
• /
• v.11 no.6
• /
• pp.77-84
• /
• 2008

The Teaching & Learning Center plays an important role in increasing the expertise of instructors and for directing the diffusion of innovation not only in primary & secondary education but also in education at the university level. In this study, the Performance Evaluation Model is devised and developed for improving the competency of the Teaching & Learning Center. It consists of three domains - (a) the planning domain, (b) the process domain, and (c) the performance domain - and 11 external indices and 8 internal indices. The Performance Evaluation Index and Guidelines are proposed based on this model.

• Journal of Distribution Science
• /
• v.16 no.2
• /
• pp.5-18
• /
• 2018

Purpose - In recent years, new retail innovations have emerged in the Japanese eyeglasses industry and grown as a retail format. The purpose of this study is to establish the process model of retail format creation by examining how a retailer creates a retail format and under what kind of environmental conditions. Research design, data, and methodology - This study pointed out the weakness of the concept of the retail format in existing research on the retail format in existing research on the retail format variation theory and suggested the concept of "Formula" to analyze an individual retailer. This study categorized the subjects categorize the subjects of retail format creation into four categories, and analyzed JINS which is the retail format leader in the Japanese eyeglass industry. This study used secondary data because it is valid. Results - This research found "product handling skill," "changes to consumer purchasing patterns," and "competitive interaction" as environmental factors influencing retail format creation. This study highlighted how JINS adapted those environmental factors to create their original formula and suggested the process model of retail format creation through the JINS case study. Conclusions - This study discussed two theoretical implications and three managerial impressions which were derived from the JINS case study. This study also discussed limitations and further research issues.

• Journal of Surface Science and Engineering
• /
• v.49 no.6
• /
• pp.498-506
• /
• 2016

Electrochemical measurement using a LSCF6428 electrode was performed to estimate the oxygen potential gradient in the electrode layer and a long time stability test was performed by applied potential to learn the overpotential effect on the LSCF6428 electrode. By fitting the observed impedance spectra, it was obtained that the amount of faradic current decreased with distance from cathode/electrolyte interface. Oxygen potential gradient was estimated to occur within 1 um region from the cathode/electrolyte interface at an oxygen partial pressure of 10-1 bar. The segregation of cation rich phases in the LSCF6428 electrode suggests that kinetic decomposition took place. However, impedance response after applying the potential showed no changes in the electrode compared with before applying potential. The obtained results suggest that segregation of a secondary phase in a LSCF6428 cathode is not related to performance degradation for solid oxide fuel cells (SOFCs).