• Title/Summary/Keyword: scientific research

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Ethnopharmacological Evaluation of Peristrophe bicalyculata Nees. for Anti-inflammatory and Analgesic Activity

  • Rathi, Anshu;Rao, Ch.V.;Khatoon, S.;Mehrotra, S.
    • Natural Product Sciences
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    • v.9 no.3
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    • pp.195-199
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    • 2003
  • The ethanolic (50% v/v) extracts of Peristrophe bicalyculata Nees. (Acanthaceae) were examined for anti-inflammatory and analgesic activities in experimental animals. P. bicalyculata in doses of 50, 100 and 200 mg/kg caused a dose dependent inhibition of swelling caused by carrageenin equivalent to 12.25-24.49% protection and 16.62-39.44% in cotton pellet induced granuloma in rats. There was a significant increase in the tail-flick reaction time in mice (18.05-76.43% protection) and analgesy-meter induced pain in rats (14.49-56.85%) protection). The extract of P. bicalyculata resulted in an inhibition of stretching episodes and the protection range of 14.49-56.85% respectively in acetic acid induced writhing.

Students Opportunities to Develop Scientific Argumentation in the Context of Scientific Inquiry: A Review of Literature

  • Flick, Larry;Park, Young-Shin
    • Journal of the Korean earth science society
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    • v.25 no.3
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    • pp.194-204
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    • 2004
  • The purpose of this literature review is to investigate what kinds of research have been done about scientific inquiry in terms of scientific argumentation in the classroom context from the upper elementary to the high school levels. First, science educators argued that there had not been differentiation between authentic scientific inquiry by scientists and school scientific inquiry by students in the classroom. This uncertainty of goals or definition of scientific inquiry has led to the problem or limitation of implementing scientific inquiry in the classroom. It was also pointed out that students' learning science as inquiry has been done without opportunities of argumentation to understand how scientific knowledge is constructed. Second, what is scientific argumentation, then? Researchers stated that scientific inquiry in the classroom cannot be guaranteed only through hands-on experimentation. Students can understand how scientific knowledge is constructed through their reasoning skills using opportunities of argumentation based on their procedural skills using opportunities of experimentation. Third, many researchers emphasized the social practices of small or whole group work for enhancing students' scientific reasoning skills through argumentations. Different role of leadership in groups and existence of teachers' roles are found to have potential in enhancing students' scientific reasoning skills to understand science as inquiry. Fourth, what is scientific reasoning? Scientific reasoning is defined as an ability to differentiate evidence or data from theory and coordinate them to construct their scientific knowledge based on their collection of data (Kuhn, 1989, 1992; Dunbar & Klahr, 1988, 1989; Reif & Larkin, 1991). Those researchers found that students skills in scientific reasoning are different from scientists. Fifth, for the purpose of enhancing students' scientific reasoning skills to understand how scientific knowledge is constructed, other researchers suggested that teachers' roles in scaffolding could help students develop those skills. Based on this literature review, it is important to find what kinds of generalizable teaching strategies teachers use for students scientific reasoning skills through scientific argumentation and investigate teachers' knowledge of scientific argumentation in the context of scientific inquiry. The relationship between teachers' knowledge and their teaching strategies and between teachers teaching strategies and students scientific reasoning skills can be found out if there is any.

A Study on the Supporting System for Scientific Data Visualization at the National Level (국가수준의 과학데이터 시각화 지원체계에 관한 연구)

  • Park, Dong-Jin;Chae, Kyun-Shik;Ryu, Beom-Jong;Lee, Sang-Tae
    • Journal of Information Management
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    • v.42 no.2
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    • pp.85-102
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    • 2011
  • Conventionally, scientific data visualization is thought of as one of activities performed by scientists during the scientific data analysis. However, recently, there exits a set of research papers which count scientific data visualization as a independent research area. They show the research subjects for studying the scientific data visualization technology and methods. In case, a scientist or group of scientists can not solve their own visualization problem due to the unskillfulness and inexperience on using visualization tool. Therefore, it needs to help them by the systematic way for solving the problem. In this study, we analyze and propose the national level scientific visualization support system for scientists. In particular, we first analyze the existing papers and find out the critical success factors. Then, by integrating the findings of the analysis, we propose the research areas which need to be focused, and the strategic direction and specific research topics for scientific data visualization support system in national level.

Analysis on Scientific Training System (과학화 훈련체계의 타당성 분석)

  • Joo Nam-Yeon;Choi Kang-Mook;Lee Soon-Ki;Seo Hyeok
    • Journal of the military operations research society of Korea
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    • v.30 no.2
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    • pp.1-12
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    • 2004
  • The army is carrying out a project of a scientific training system which enables company level mutual training in infantry division to enhance battle command capability and combat skill. In this paper, we tried to prove the necessities of a scientific training system based on previously conducted training results. We drew comparison among proposed alternatives. To obtain the results we used hierarchical analysis methodology And cost and training effectiveness analysis were conducted.

An Entity-Aspect Model for Statistical and Scientific Databases (통계(統計)/과학(科學) 데이타 베이스를 위한 개체(個體)-측면(側面) 모형(模型))

  • Yoo, Cheol-Jung
    • Proceedings of the KIEE Conference
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    • 1987.07b
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    • pp.1148-1152
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    • 1987
  • This paper analyzes the statistical and scientific entity-aspect model for statistical and scientific databases(SSDB's). The statistical and scientific entity-aspect model(SEAM) is defined an example of the application of the statistical and scientific entity-aspect model is represented. Finally, the statistical and scientific entity-aspect model as a design tool for SSDB is evaluated and the further research areas are suggested.

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A Survey of Elementary School Students' Perception of Data-based Scientific Inquiry (데이터 기반 과학탐구에 대한 초등학생의 인식 조사)

  • Jeong, Eunju;Son, Jeongwoo
    • Journal of Science Education
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    • v.43 no.2
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    • pp.227-238
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    • 2019
  • In this study, we investigated the perception of elementary school students on inquiry activities and collaborative problem-solving ability in data-based scientific inquiry. For this purpose, 20 data-based scientific inquiry classes were conducted in 26 elementary school students in Gyeongnam City. After selecting the inquiry problem, students conducted an inquiry process to collect data using digital inquiry instruments. The following results were obtained through questionnaires and interviews after the classes: First, students perceived the step on 'inquiry design and execution' as the most useful in the data-based scientific inquiry. Second, students perceived that their scientific ability and cooperation improved through data-based scientific inquiry, with the selection of inquiry problems being the most difficult. Third, students perceived positively the improvement of cooperative problem-solving ability. From the above results, it was found that data-based scientific inquiry is necessary to improve the elementary school students' scientific inquiry ability and cooperative problem-solving ability. Based on this research, we hope that the development and research of various inquiry activities will provide opportunities for inquiry that can cultivate various abilities needed for students living in the future.

Quercetin, A Bioflavonoid, Protects Against Oxidative Stress-related Gastric Mucosal Damage in Rats

  • Rao, Ch.V.;Ojha, S.K.;Govindarajan, R.;Rawat, A.K.S.;Mehrotra, S.;Pushpangadan, P.
    • Natural Product Sciences
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    • v.9 no.2
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    • pp.68-72
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    • 2003
  • Quercetin and its sugar conjugates are the most abundantly distributed bioflavonoids and represent the largest proportion of flavonols in the plant kingdom. The present study was undertaken to demonstrate the effect of quercetin on the role of reactive oxygen species (ROS) in the development of gastric ulcers in rats. Administration of quercetin in doses of 50, 100 and $200\;mg\;kg^{-1}$ twice daily for 5 days, showed dose dependent significant protection against ethanol (EtOH), aspirin (ASP), cold-restraint stress (CRS) and pylorus ligation (PL) -induced gastric ulcer models and the results were comparable with those elicited by sucralfate. The thiobarbituric acid reactive substances in the stomach mucosa, an index of lipid peroxidation and regulation of plasma corticosterone were significantly increased in CRS-induced gastric ulceration. The queroetin $(100\;mg\;kg^{-1})$ and reduced glutathione effectively inhibited gastric lesions induced by CRS with a significant decrease in the lipid peroxidation and plasma corticosterone. These results indicate that quercetin a bioflavonoid exerts its antiulcer effect in light of free radical scavenging and plasma corticosterone in cold restraint stress ulcers.

Real-time Assay of Toxic Lead in In Vivo Living Plant Tissue

  • Ly, SuwYoung;Kim, Nack Joo;Youn, Minsang;Kim, Yongwook;Sung, Yeolmin;Kim, Dohoon;Chung, Tackhyun
    • Toxicological Research
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    • v.29 no.4
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    • pp.293-298
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    • 2013
  • A method of detecting lead was developed using square wave anodic stripping voltammetry (SWASV) with DNA-carbon nanotube paste electrode (CNTPE). The results indicated a sensitive oxidation peak current of lead on the DNA-CNTPE. The curves were obtained within a concentration range of 50 $ngL^{-1}-20mgL^{-1}$ with preconcentration time of 100, 200, and 400 sec at the concentration of $mgL^{-1}$, ${\mu}gL^{-1}$, and $ngL^{-1}$, respectively. The observed relative standard deviation was 0.101% (n = 12) in the lead concentration of 30.0 ${\mu}gL^{-1}$ under optimum conditions. The low detection limit (S/N) was pegged at 8 $ngL^{-1}$ ($2.6{\times}10^{-8}M$). Results showed that the developed method can be used in real-time assay in vivo without requiring any pretreatment and pharmaceutical samples, and food samples, as well as other materials requiring water source contamination analyses.

The Study on the influence of MBL Exhibition Class on the Eelementary school students' Academic Achievement, Scientific Research Abilities and Affective Characters (MBL 시범 수업이 초등학생의 학업성취도, 과학탐구능력 및 정의적 특성에 미치는 영향)

  • Heo, Eun-Young;Yoo, Pkyoung-Kil
    • Journal of the Korean Society of Earth Science Education
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    • v.3 no.1
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    • pp.36-46
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    • 2010
  • The purpose of this study is to find out the influence of MBL Exhibition Class on the Elementary School students' academic achievement, scientific research abilities and affective characters. For the purpose, three classes were sampled in the 5th grade of an elementary school. Among the three classes, two were designated as the comparative classes consisted of 68 students and the other was the experimental class, 33 students. The comparative classes were given lessens according to the content presented in the textbook of 7th Education Curriculum and the experimental class was given re-built lessons with using MBL machines. Before and after giving lessons, students of both classes took a test for science academic achievement. And also the scientific research abilities and affective characters were examined. The conclusions from this study is as follows. First, according to the result of science academic achievement test after giving lessons, the mean of the experimental class was higher than that of the comparative classes meaningfully. Second, scientific research abilities of the experimental class was shown higher than that of the comparative classes meaningfully. Specially, basic research abilities were improved very meaningfully and only hypothesis-building ability was improved among integrated research abilities. Third, it doesn't seem that MBL exhibition class is effective on affective characters(interest, attitudes).

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