• Journal of Physiology & Pathology in Korean Medicine
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• v.35 no.5
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• pp.125-131
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• 2021

The scientific understanding of Korean medicine theory remains largely unknown, since there is a lack of proper methods to investigate its complex and unique characteristics. Here, we introduce a drug-centered approach, a novel method to investigate Korean medicine theory by analyzing the mechanisms of herbal medicines. This method can be effectively conducted by employing network pharmacology that can analyze the systems-level mechanisms of herbal medicines on a large scale. Firstly, we introduce the method of network pharmacology that are applied to analyze the mechanisms of herbal medicines in a step-by-step manner. Then, we show how the drug-centered approach employing network pharmacology can be applied to investigate Korean medicine theory by describing studies that identify the biological correlates of the cold-hot nature of herbs, spleen qi deficiency syndrome, or Sasang constitution. Finally, we discuss the limitations and future directions of the proposed approach in two aspects: The methods of network pharmacology for a drug-centered approach and the process of inferring Korean medicine theory through it. We believe that a drug-centered approach employing network pharmacology will provide an advanced scientific understanding of Korean medicine theory and contribute to its development by generating biologically plausible hypothesis.

• Journal of the Korea Convergence Society
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• v.11 no.6
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• pp.183-189
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• 2020

The objective of this research was to provide an objective and scientific basis for the effect of mid-advertising on viewers' rights by conducting an empirical study on how mid-program advertising affects viewer satisfaction and interest from the viewers' perspective. The experiment was conducted on 210 subjects to investigate the difference between viewers' interest in the program and purchase intention price. The results did not support the hypothesis that advertisements inserted in the middle of television programs would affect the dependent variables. The theoretical and practical implications of the mid-program advertisements on the interests of viewers were discussed.

• Journal of Korean Institute of Industrial Engineers
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• v.41 no.1
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• pp.105-114
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• 2015

An empirical analysis study applied to evaluate the effect of critical factors for technology transfer. The research aims to suggest ways of political support in order to facilitate technological transfer and commercialization of public research institute'technology. Based on previous researches, it is determined that five critical factors which effect on technology commercialization. These critical factors are used to derive the order of priority, attribute of the success, and failure factors. The result of this research emphasized on both roles of technology introduction motivation and type of technology transfer. In order to collect data for this research, it is carried out that survey and field study toward to technology user such as manufacturing companies which have contracted with institute A. This research has a meaning in aspects of verification of previous hypothesis through scientific approach and new findings of a significant factor that motivation determines the success or failure of technology commercialization.

• The Journal of the Korea Contents Association
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• v.20 no.5
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• pp.118-127
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• 2020

The paper introduces trends and methodological challenges of quantitative Korean text analysis by using the case studies of academic and news media articles on "migration" and "immigration" within the periods of 2017-2019. The quantitative text analysis based on natural language processing technology (NLP) and this became an essential tool for social science. It is a part of data science that converts documents into structured data and performs hypothesis discovery and verification as the data and visualize data. Furthermore, we examed the commonly applied social scientific statistical models of quantitative text analysis by using Natural Language Processing (NLP) with R programming and Quanteda.

• Korean Journal of Human Ecology
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• v.24 no.4
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• pp.513-529
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• 2015

This study performed corroborative analysis by establishing hypothesis so as to corroboratively define the effect on brand attitude of psychological risk recognition in the case where consumers reading negative media news related to bakery recognize crisis communication on the basis of which point. According to corroborative analysis, the role of psychological crisis perception as parameter is confirmed in the causal relation between crisis communication recognition and brand attitude. Such result of study confirms that the positive change in crisis communication recognition reduces psychological risk perception to bakery products and such psychological risk perception eventually become factor which affects brand attitude over products. Such result of study suggests that when reading negative media news on bakery, the influence on consumer's evaluation of news on the basis of certain point and the influence on the formation of causal relation between psychological risk perception and brand attitude has scientific ground. In the aspect, the main result of this study is to find the clue that when comparing precedent study between crisis communication recognition and brand attitude, psychological risk perception is realized with brand attitude as media by verifying the parameter role of psychological risk perception.

• Journal of Environmental Health Sciences
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• v.40 no.4
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• pp.265-278
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• 2014

Microbes such as bacteria, fungi, archaea, protists, and viruses are ubiquitous and people are exposed to them continuously. Endotoxin is a component of the outer membrane of Gram-negative bacteria and a potent proinflammaotry substance. When a person is exposed to environmental endotoxin, an innate immune response is initiated upon the initial recognition and this response produces various inflammatory mediators and recruits inflammatory cells to the exposed tissues. A purified chemical form of endotoxin is called lipopolysaccharide (LPS), and the lipid A portion of the molecule is a biologically active moiety. Exposure to endotoxin may result in various complex health effects depending on time, route, and dose of exposure, as well as host susceptibility. Gene-environment interactions play important roles in health effects of endotoxin exposure, e.g. development or aggravation of asthma. To accurately assess exposure to endotoxin in environmental or epidemiologic studies, methods of sampling, extraction, and analysis must be carefully selected since the selected methods may substantially affect analytical results and there is no internationally-agreed standard method to date. The lack of a standardized method hampers the establishment of exposure-response relationships. While an internationally-agreed health-based exposure limit does not exist, the Dutch Expert Committee on Occupational Safety recently recommended $90EU/m^3$ as a health-based occupational exposure limit. The current article reviews various scientific issues on how we measure environmental endotoxin and the health effects of endotoxin exposure.

• Korean Journal of Oriental Medicine
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• v.13 no.3
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• pp.11-20
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• 2007

Haedae(海帶, haidai) is representative herb from seaweeds, but its origin is still confusing. Thus we analyzed its origin on the basis of classics of oriental medicine. The scientific name of Haedae corresponds to Zostera marina, according to the folkloric use. But, it is Laminaria japonica, according to its habitat, morphological feature, and the korean name on the medical books in Joseon since 17c. In the remote past, it seemed that two groups were segragated by the name of Zostera marina Haedae and Laminaria japonica Haedae. However, it is thought that this two trends were mixed up when medical knowledge was compiled in Song Dynasty era. Documental support inclined to Laminaria japonica, but it is too early to conclude that Laminaria japonica is the Haedae. To prove this hypothesis, further study is required to investige whether Laminaria japonica or Zostera marina has mentioned efficacies of Haedae used for the treatment of wen, San syndromes, edema, scrofula, etc. And we have need of research that solve the origin problem of Gonpo(Laminariae thallus) on the assumption that Laminaria japonica is Haedae.

• Archives of design research
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• v.21
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• pp.1-12
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• 1997

This research is that it could use a theory from a .cognitive science, making a hypothesis to explain the thingking steps of designing, adapting the problem solving of the design from knowledge of a cognitive science, to meet the possiblity which it can be developed the new way of the thinking. Design is a field where it needs a complexity with hi-brain activities. And cognitive science is a science which it study human brain activities. However, it is also quite possible to bo adaped over all design by linking with design and cognitive science. I explaned the ideation of the thinking steps on this study by the knowledge of cognitive science, to observe to be possible. I found out the new ways of possibilities from design thinking process. It is a result that I've been interpretated the design process and the thinking process out of the theory of knowledge structure.

• Journal of Science Education
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• v.34 no.2
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• pp.421-431
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• 2010

The purpose of this study was to identify instructional components supporting students' interest and creativity in American middle school science classrooms. Two 7th grade classrooms were selected, and observed for 11 class periods each. Results showed that hands-on and small group activities were the most effective ways to increase students' interest. The teachers' instructional approaches, such as individualized paced teaching, sufficient peer teaching, permissive atmosphere, various media, and purpose-focused summary game were found to influence students' interest. To enhance students' creativity, increasing interest, making hypothesis, and trying to various experimental method with sufficient time were identified as effective components.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.11
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• pp.413-419
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• 2020

This research focuses on the analysis of factors affecting the market share of retailers in Vietnam. This research uses Smith and Chaffey's (2005) 5Ss e-marketing model for analysis, which include Sell, Serve, Speak, Save, and Sizzle. Both quantitative and qualitative methods will be used to conduct the study. The researchers collected information from customers, managers, and directors in 25 retailers in Vietnam. A survey questionnaire was delivered to 15 people in each of the retailers who are customers, managers and directors. The researcher used the SPSS 16.0 software to analyze the data collected and in-depth interviews were carried out with the purpose of testing the hypothesis as well as the overall framework of the research. Out of the 375 questionnaires delivered, 360 were returned. The means of 23 items in the survey questionnaire ranged from 3.3733 to 4.3533 representing the outcome of the descriptive analysis. Research results showed that Cronbach's Alpha coefficient of five factors affecting the market share of the retailers is sizzle, save, sell, serve and speak. This research has proposed some implications for the market share of retailers, including technology enhancement for full message delivery, ways to approach target customers, and improving product diversity.