• Title/Summary/Keyword: schistocidal activity evaluated

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Synthesis of certain thiaxanthones as potential schistosomicidal agents

  • El-Kerdawy, M.M.;El-Eman, A.A.;El-Subbagh, H.I.
    • Archives of Pharmacal Research
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    • v.9 no.1
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    • pp.25-28
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    • 1986

  • Twenty nine substituted thiaxanthone derivatives were synthesized for schistosomicidal evaluation. The compounds, 1-morpholino-4-methyl-6-nitrothiaxanthone and 1-(2-diethyl-aminoethyl-amino)-4 methyl-6-nitrothiaxanthone dipicrate were found to possess promising schistosomicidal activity against Schistosoma mansoni in mice.

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