• Journal of Korean Academy of Nursing
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• v.27 no.4
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• pp.943-952
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• 1997

This study was done to analyze the effects of prompted voiding therapy on urinary incontinence in elderly patients in an elderly care hospital. Specifically, this study looks to evaluate the effects of prompted voiding as an intervention for improving independent voiding and also identified the relationship of urinary continence to cognitive, emotional, and physical factors. The study was based on a pre-experimental design used to evaluate the effects of prompted voiding therapy on an experimental group without a control group. An experimental group of 143 patients was selected through convenience sampling from patients in an elderly care hospital. The data was collected from November 4 to December 14, 1996. Prompted voiding therapy is a behavioral therapy for managing incontinence and it is applied to patients who are cognitively impaired and dependent. In this study, the patients were asked at each designated time whether or not they had to urinate. If they answered yes, they were either given a bedpan or were assisted to the bathroom, and if the patient answered no, their diaper was checked to determine whether or not it was wet. The results were then recorded on the patients urinary voiding record. The urinary voiding score based on the model presented by Burton(1984), Burke and Walsh(1992), Chenitz, Stone & Salisbury(1991) was modified and used as a tool in this study. After forty six out of the total of 143 patients were selected for interviews through random sampling the levels of cognitive functions, mental depression and ADL(activities of dally life) within the given time frame were measured. In this study, the cognitive function was measured using the scale developed by Kabhn, Goldfarb, Pollack & Peck(1960), elderly mental depression, using the tool developed by Sheikh & Yesavage(1986), and the ADL(activities of dally living), through the Barthel Index. The data was analyzed through SPSS windows for descriptive statistics, repeated measured ANOVA and Pearson's correlation. According to the results of the study, the application of the prompted voiding therapy can improve the voiding pattern of patients. It was shown especially that incontinence could be controlled by the intervention developed according to the individual voiding pattern. In terms of the relationship between cognitive function, mental depression and ADL and the voiding function score, a close correlation was not found. It was shown that urinary incontinence can be improved through therapy even though patients have problems nth their cognitive, mental and physical functions.

• Korean Journal of Clinical Pharmacy
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• v.25 no.4
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• pp.238-245
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• 2015

Background: Pharmacy schools newly adopted a 6-year program strengthening clinical knowledge since 2011 in Korea. The clinical training under the guidance of preceptors at hospital sites is a requisite for pharmacy students during the last year of undergraduate course. It has been rarely studied on the hospital pharmacists' perspective regarding being a preceptor or teaching pharmacy students. Objectives: This study aimed to examine the hospital pharmacists' intention toward student training and to identify the relevant factors among the individual pharmacists' characteristics and working environment within the theoretical frame of the Theory of Planned Behavior (TPB). Method: A mail-survey was conducted for pharmacists working in tertiary hospitals in Seoul and Incheon. The survey questionnaire consisting of 131 questions with a 5-likert scale was developed for investigating pharmacists' attitude, subjective norm, perceived behavioral control and the intention to teach pharmacy students as well as other demographic variables. To estimate the construct validity of components, factor analysis was conducted and Cronbach's alpha was calculated to estimate the reliability of the observed variables. Statistical analyses of one-way variance analysis and multiple regression analysis were performed using SPSS 18.0. Results: The survey response rate was 53% (116/210) and the three constructs of attitude (r = .519), subjective norm (r = .233) and perceived control (r = .392) have appropriate correlations with the intention, proving the appropriateness of using the TPB model. Pharmacists working in inpatient (mean = 3.45) and outpatient clinics (mean = 3.34) generally showed positive intention for teaching. The attitude (${\beta}=.432$, p < 0.01) and perceived control (${\beta}=.270$, p < .01) constructs were significant predictors of the intention. Both age (r = 0.246, p = 0.017) and length of career (r = 0.310, p = 0.002) were positively related with the perceived control. Conclusion: Hospital pharmacists showed generally positive intention to provide student training in spite of the concern on their limited perceived behavioral control. Future research to find the actual barriers pharmacists faced in educating students need to be conducted.

• The Korean Journal of Ecology
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• v.26 no.5
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• pp.237-246
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• 2003

A mountain village is defined as that which is autogenously formed over at least 100 years and supported by agricultural yields and forest products and forest area portion of which is over 70% in Guidelines for the Comprehensive Development Planning of Mountain Village. Recently, concerns about management planning of the Green and Eco-Village causes researches related to the Mountain Village's economics, tourism attractiveness, experience programming and investigation of the ecosystem and environment based on the village area. This kind of eco-village project should be supported by ecological evaluation of its spatial structure. But there is rare research of the village spatial structure studied from the ecological viewpoint originally. The purpose of this study is to interpret the spatial structure of Korean mountain village on the landscape ecological paradigm. The paradigm components are patches, corridors, networks, and matrix which explain the land and spatial structure at landscape scale. For this purpose, we selected two case study areas- Sansu and Ajick villages in Gimje city, Jeonlabukdo. We interpreted and evaluated the spatial structure by three steps: (1) to clarify the existing land mosaic pattern by land use mapping (2) to estimate the pore size as development area in matrix (3) to investigate the funnel effect of patch shape. These landscape ecological steps and frameworks could be applied for the proper methodology as fundamentals of eco-village planning and design.

• Journal of the Korean earth science society
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• v.36 no.3
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• pp.199-209
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• 2015

The Atlantic meridional overturning circulation (AMOC), driven by high density water sinking around Greenland serves as a global climate regulator, because it transports heat and materials in the climate system. We analyzed the mechanism of AMOC on a decadal time scale simulated with the HadGEM2-AO model. The lead-lag regression analysis with AMOC index shows that the decadal variability of the thermohaline circulation in the Atlantic Ocean can be considered as a self-sustained variability. This means that the long-term change of AMOC is related to the instability which is originated from the phase difference between the meridional temperature gradient and the ocean circulation. When the overturning circulation becomes stronger, the heat moves northward and decreases the horizontal temperature-dominated density gradients. Subsequently, this leads to weakening of the circulation, which in turn generates the anomalous cooling at high latitudes and, thereby strengthening the AMOC. In this mechanism, the density anomalies at high latitudes are controlled by the thermal advection from low latitudes, meaning that the variation of the AMOC is thermally driven and not salinity driven.

• Journal of KIBIM
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• v.1 no.2
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• pp.19-23
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• 2011

The planning stage of an architectural project has much more significant effects on the cost or outcome of the project than other stages of the project. In addition, the importance of architectural planning has been further increasing according to the recent trend of construction projects becoming larger in scale and more complex. In spite of this, the current situation is that the planning stage work is not being systematically managed. Accordingly, the purpose of this study was to develop a BIM-based simulation system for providing support during architectural planning stage such as spatial planning & review, cost review, project owner requirements management, etc. It is easy to review various alternatives using this system that allows not only the modeling of space object modeling but also the instantaneous review of spatial area & layout, cost, etc. based on object information. In addition, it can be used as a communication tool with the project owner as it provides the visualized information and quantitative data of the building model, and the information created through this system can be delivered to the following stage for usage. It is thought that using this system, the entire project work including the architectural planning stage can be supported and even contributing to the advancement of architectural process.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.11 no.1
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• pp.85-95
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• 2016

Generally a venture capital aims at investment and support Venture businesses that signifies a start-up which has high technologies but frailty of the economy so that raise fund from financial agencies at high risk rate, it has high risk but when the venture businesses launch into general orbit, the venture capital guarantee high-rate profits. Venture capital do not just provide risk capital but also takes a role as a mentor for continuous growth with total consulting service at business and technical management. Also it offers in-depth support to reform the supported enterprise in order to enhance the competitive. Venture capital receives attention for years as a principal agent to be promoted strategically at national level. Bio venture, a major concern of venture capital and one of core industries in Korea, is different from other industries because it needs long-term and large scale of investment. these factors bring about difficulties in an investment and growth. Therefore, it is very important to identify growth and profitability of start-ups and small and venture businesses with long-term appreciation above all other industries. This research analyze management results of bio venture businesses empirically by investment from venture capital. according to the results, bio venture businesses need huge capital and a long gap of time, henceforth, formation of model for growth is necessary with angel investing as well as venture capital. Since, there are not many listed bio venture businesses, significant statistical result would be limited. This research studied at only economic focus but further study need to examine a question from various angles.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.10 no.3
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• pp.1-13
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• 2015

Strong ties such as family members, relatives and close friends have been widely acknowledged as a vital factor when a potential entrepreneur attempts to initiate entrepreneurial activity. Recent theoretical arguments focus that family social capital, a form of social capital, that is embedded in family relationships can contribute to venture creation as well as to the development of competitive advantage for established firms. Meantime, there have been arguments that the most dominant single entrepreneurial ethnic group in the world is the Chinese people, while the People's Republic of China is widely recognized as fast growing economic power that is driven by entrepreneurial ventures in a large scale. This study tests the effect of perceived relational supports typically being provided by family members, close relatives and friends on forming self-efficacy and entrepreneurial motivation of university students by using samples collected from 4 Korean Universities(Wonkwang, Baekseok, Soongsil and Dankook university) and Guangzhou University in China. The mediating of self-efficacy was also tested to gain better understanding of the role of the variable. The results of the study suggest that 1) both self-efficacy and entrepreneurial motivation are influenced positively by the perceived relational supports, 2) self-efficacy of university students affects their entrepreneurial motivation positively, 3) self-efficacy is appeared to be mediated partially for China in between perceived relational supports and entrepreneurial motivation, but the same variable is exhibited a full mediation in the same path of the research model for Korea, which was a distinction between the students of two countries in this study. Discussion and practical implication on the results are provided.

• BMB Reports
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• v.51 no.11
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• pp.584-589
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• 2018

Secondary prevention via earlier detection would afford the greatest chance for a cure in premalignant lesions. We investigated the exomic profiles of non-malignant and malignant changes in head and neck squamous cell carcinoma (HNSCC) and the genomic blueprint of human papillomavirus (HPV)-driven carcinogenesis in oropharyngeal squamous cell carcinoma (OPSCC). Whole-exome (WES) and whole-genome (WGS) sequencing were performed on peripheral blood and adjacent non-tumor and tumor specimens obtained from eight Korean HNSCC patients from 2013 to 2015. Next-generation sequencing yielded an average coverage of $94.3{\times}$ for WES and $35.3{\times}$ for WGS. In comparative genomic analysis of non-tumor and tumor tissue pairs, we were unable to identify common cancer-associated early mutations and copy number alterations (CNA) except in one pair. Interestingly, in this case, we observed that non-tumor tonsillar crypts adjacent to HPV-positive OPSCC appeared normal under a microscope; however, this tissue also showed weak p16 expression. WGS revealed the infection and integration of high-risk type HPV16 in this tissue as well as in the matched tumor. Furthermore, WES identified shared and tumor-specific genomic alterations for this pair. Clonal analysis enabled us to infer the process by which this transitional crypt epithelium (TrCE) evolved into a tumor; this evolution was accompanied by the subsequent accumulation of genomic alterations, including an ERBB3 mutation and large-scale CNAs, such as 3q27-qter amplification and 9p deletion. We suggest that HPV16-driven OPSCC carcinogenesis is a stepwise evolutionary process that is consistent with a multistep carcinogenesis model. Our results highlight the carcinogenic changes driven by HPV16 infection and provide a basis for the secondary prevention of OPSCC.

• Journal of Mechanical Science and Technology
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• v.20 no.12
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• pp.2292-2314
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• 2006

Efficient numerical method is developed for the prediction of aerodynamic noise generation and propagation in low Mach number flows such as aeolian tone noise. The proposed numerical method is based on acoustic/viscous splitting techniques of which acoustic solvers use simplified linearised Euler equations, full linearised Euler equations and nonlinear perturbation equations as acoustic governing equations. All of acoustic equations are forced with immersed surface dipole model which is developed for the efficient computation of aerodynamic noise generation and propagation in low Mach number flows in which dipole source, originating from unsteady pressure fluctuation on a solid surface, is known to be more efficient than quadrupole sources. Multi-scale overset grid technique is also utilized to resolve the complex geometries. Initially, aeolian tone from single cylinder is considered to examine the effects that the immersed surface dipole models combined with the different acoustic governing equations have on the overall accuracy of the method. Then, the current numerical method is applied to the simulation of the aeolian tones from twin cylinders aligned perpendicularly to the mean flow and separated 3 diameters between their centers. In this configuration, symmetric vortices are shed from twin cylinders, which leads to the anti-phase of the lift dipoles and the in-phase of the drag dipoles. Due to these phase differences, the directivity of the fluctuating pressure from the lift dipoles shows the comparable magnitude with that from the drag dipoles at 10 diameters apart from the origin. However, the directivity at 100 diameters shows that the lift-dipole originated noise has larger magnitude than, but still comparable to, that of the drag-dipole one. Comparison of the numerical results with and without mean flow effects on the acoustic wave emphasizes the effects of the sheared background flows around the cylinders on the propagating acoustic waves, which is not generally considered by the classic acoustic analogy methods. Through the comparison of the results using the immersed surface dipole models with those using point sources, it is demonstrated that the current methods can allow for the complex interactions between the acoustic wave and the solid wall and the effects of the mean flow on the acoustic waves.

• The Journal of Engineering Geology
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• v.23 no.4
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• pp.467-476
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• 2013

With increasing interest in environmental issues and the quality of surface water becoming inadequate for water supply, the Korean government has launched a groundwater development policy to satisfy the demand for clean water. To drive this policy effectively, it is essential to guarantee the accuracy of sustainable groundwater yield and groundwater use amount. In this study, groundwater use was monitored over several years at various locations in Korea (32 cities/counties in 5 provinces) to obtain accurate groundwater use data. Statistical analysis of the results was performed as a method for estimating rational groundwater use. For the case of groundwater use for living purposes, we classified the cities/counties into three regional types (urban, rural, and urban-rural complex) and divided the groundwater facilities into five types (domestic use, apartment housing, small-scale water supply, schools, and businesses) according to use. For the case of agricultural use, we defined three regional types based on rainfall intensity (average rainfall, below-average rainfall, and above-average rainfall) and the facilities into six types (rice farming, dry-field farming, floriculture, livestock-cows, livestock-pigs, and livestock-chickens). Finally, we developed groundwater-use estimation equations for each region and use type, using cluster analysis and regression model analysis of the monitoring data. The results will enhance the reliability of national groundwater statistics.