• Title/Summary/Keyword: scale-model

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Characteristic Analysis and Prediction of Debris Flow-Prone Area at Daeryongsan (대룡산 토석류 특성 분석 및 위험지역 예측에 관한 연구)

  • CHOI, Young-Nam;LEE, Hyung-Ho;YOO, Nam-Jae
    • Journal of the Korean Association of Geographic Information Studies
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    • v.21 no.3
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    • pp.48-62
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    • 2018
  • In this study, landslide of debris flow occurred at 51 sites around Daeryounsan located in between Chuncheon-si and Hongcheon-gun during July in 2013 were investigated in field and behavior characteristics of debris flow were analyzed on the basis of records of rainfall and site investigation. According to debris flow types of channelized and hill slope, location and slope angle of initiation and deposit zone, and width and depth of erosion were investigated along entire runout of debris flow. DEM(Digital Elevation Model) of Daeryounsan was constructed with digital map of 1:5,000 scale. Land slide hazard was estimated using SINMAP(Stability INdex MAPping) and the predicted results were compared with field sites where debris flow occurred. As analyzed results, for hill slope type of debris flow, predicted sites were quite comparable to actual sites. On the other hand, for channelized type of debris flow, debris flow occurrence sites were predicted by using stability index associated with topographic wetness index. As analyzed results of 4 different conditions with the parameter T/R, Hydraulic transmissivity/Effective recharge rate, proposed by NRCS (Natual Resources Conservation Service), predicted results showed more or less different actual sites and the degree of hazard tended to increase with decrease of T/R value.

Effect of Dendritic Cell Based Cancer Vaccine Using Allogeneic Tumor Cell Lysate in Melanoma Pulmonary Metastasis Model (동종 종양 세포 용해액을 이용한 수지상 세포 항암 백신의 흑색종 폐암 전이 모델에서의 효과 연구)

  • Lee, Young-Joon;Kim, Myung-Joo;In, So-Hee;Choi, Ok-Mi;Baek, So-Young;Kwon, Young-Do;Lee, Hyun-Ah
    • IMMUNE NETWORK
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    • v.5 no.3
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    • pp.163-171
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    • 2005
  • Background: To perform the successful dendritic cell-based cancer immunotherapy one of the main issues to be solved is the source of antigen for DC pulsing. Limitations occur by using auto-tumor lysate due to the difficulties obtaining enough tumor tissue(s) quantitatively as well as qualitatively. In this study the possibility of allogeneic tumor cell lysate as a DC pulsing antigen has been tested in mouse melanoma pulmonary me tastasis model. Methods: B16F10 melanoma cells $(1{\timeS}10^5/mouse)$ were inoculated intra venously into the C57BL/6 mouse. Therapeutic DCs were cultured from the bone marrow myeloid lineage cells with GM-CSF and IL-4 (1,000 U/ml each) for 7 days and pulsed with lysate of either autologous B16F10 (B-DC), allogeneic K1735 (C3H/He origin; K-DC) or CloneM3 (DBA2 origin; C-DC) melanoma cells for 18 hrs. Pulsed-DCs $(1{\times}10^6/mouse)_{[CGP1]}$ were injected i.p. twice with one week interval starting from the day 1 after tumor cell inoculation. Results: Without observable toxicity, allogeneic tumor cell lysate pulsed-DC induced the significantly better anti-tumor response (tumor scale: $2.7{\pm}0.3,\;0.7{\pm}0.3\;and\;0.3{\pm}0.2$ for saline, B-DC and C-DC treated group, respectively). Along with increased tumor specific lymphocyte proliferations, induction of IFN-${\gamma}$ secretion against both auto- and allo-tumor cell lysates was observed from the DC treated mice. (w/B16F10-lysate: $44.97{\pm}10.31,\;1787.94{\pm}131.18,\;1257.15{\pm}48.27$, w/CloneM3 lysate: 0, $1591.13{\pm}1.83,\;1460.47{\pm}86.05pg/ml$ for saline, B-DC and C-DC treated group, respectively) Natural killer cell activity was also increased in the mice treated with tumor cell lysate pulsed-DC ($8.9{\pm}_{[CGP2]}0.1,\;11.6{\pm}0.8\;and\;12.6{\pm}0.7%$ specific NK activity for saline, B-DC and C-DC treated group, respectively). Conclusion: Conclusively, promising data were obtained that allogeneic-tumor cell lysate can be used as a tumor antigen for DC-based cancer immunotherapy.

A Study on the Model Development and Empirical Application for Predicting the Efficiency and Optimum Size of Investment in Domestic Seaports (국내항만투자의 효율성 및 적정 투자규모 예측을 위한 모형개발 및 실증적 적용에 관한 연구)

  • Park, Ro-Kyung
    • Journal of Korea Port Economic Association
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    • v.26 no.3
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    • pp.18-41
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    • 2010
  • The purpose of this paper is to show the empirical measurement way for predicting the seaport efficiency by using Super SBM(Slack-based Measure) with Wilcoxson signed-rank test under CRS(constant returns to scale) condition for 20 Korean ports during 11 years(1997-2007) for 3 inputs(port investment amount, birthing capacity, and cargo handling capacity) and 5 outputs(Export and Import Quantity, Number of Ship Calls, Port Revenue, Customer Satisfaction Point for Port Service and Container Cargo Throughput). The main empirical results of this paper are as follows. First, Super SBM model has well reflected the real data according to the Wilcoxon signed rank test, because p values have exceeded the significance level. Second,Super-SBM has shown about 87% of predicting ratio for the ports efficiency and the optimal size of investment in domestic seaport. The policy implication to the Korean seaports and planner is that Korean seaports should introduce the new methods like Super-SBM method with Wilcoxon signed rank test for predicting the efficiency of port performance and the optimal size of investment as indicated by Panayides et al.(2009, pp.203-204).

Enhancing Production of Terpenoids in Metabolically Engineered Transgenic Spearmint (Mentha spicata L.) by Salt and Fungal Elicitors

  • Choi, Myung Suk;Park, Dong Jin;Song, Hyun Jin;Min, Ji Yun;Kang, Seung Mi;Lee, Chong Kyu;Cho, Kye Man;Karigar, Chandrakant;Kim, Ho Kyoung;Kang, Young Min
    • Journal of Forest and Environmental Science
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    • v.30 no.2
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    • pp.243-252
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    • 2014
  • Forest tree species usually takes for long periods to be harvested and cultivated but spearmints are a good model system for woody plant because of reducing and shortening cultivation time. Spearmints are good model plants (Mentha species) for research about terpenoids production and industrial essential oil manufacture. Isopentenyl pyrophosphate isomerase (Iso) and limonene synthase (Limo) are the key enzymes of terpenoid biosynthesis pathway. Transgenic and wild spearmints (Mentha spicata, MS) were cultured in vitro and assessed for the essential oil contents. The content of essential oil of transgenic spearmint also was enhanced slightly depending on the target terpenoid genes. In an attempt to increase productivity of terpenoids further, salt and fungal elicitation strategy was adopted on transgenic Mentha spicata. The salt (800 mM NaCl) as abiotic and two fungi (Botrytis cinerea and Glomerella cingulata) as biotic were used for elicitors. In the absence of salt stress four terpenoids were detected from the spearmint extracts, all of them being monoterpenes. On the other hand, the transgenic (MSIso) extracts contained eleven terpenoids (10 monoterpenes and 1 phenylpropene) while transgenic (MSLimo) extracts contained seven monoterpenes. After 3 days of fungal infection, the resistance indices further increased to 4.38, 3.89 and 2.04 for wild type, MSIso and MSLimo, respectively. The salt and fungal elicitators proved beneficial towards modifying both the terpenoids profile and improvement in the composition of essential oil. These results have important applications for the large-scale production of essential oils and forest biotechnology with respect to spearmint.

Experimental Evaluation of the Punching Shear Strength with Lightweight Aggregate Concrete Slabs (경량골재 콘크리트 바닥판의 펀칭전단강도의 실험적 평가)

  • Kim, Jung-Joong;Moon, Ji-Ho;Youm, Kwang-Soo
    • Journal of the Korea Concrete Institute
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    • v.26 no.3
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    • pp.361-367
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    • 2014
  • This paper investigates the punching shear strength of lightweight aggregate concrete (LWAC) slabs through a series of experimental study. Five full scale slabs were constructed using normal concrete and four different types of LWAC. Each lightweight aggregate (LWA) used in this study had different sources (clay, shale, or slate) and shapes (crushed or spherical shape). Based on the test results, the effect of the lightweight aggregates (LWA) on the punching shear behavior was investigated. From the test results, it was found that the punching shear failure surface of LWAC slab with spherical shape coarse aggregate was less inclined than that with crushed shape coarse aggregate, which resulted in an increase of the area of the shear failure surface. As a result, it leads to the increased punching shear strength of the slab. On the other hand, the failure surfaces of LWAC slab with crushed shape coarse aggregate and normal coarse aggregate were inclined similarly. Finally, the test results of this study were compared with the punching shear strength obtained from current design models, such as ACI and CEB-FIP, to examine the validation of current design model to predict the punching shear strength of the LWAC slab.

Steam Gasification of Coal and Petroleum Coke in a Thermobalance and a Fluidized Bed Reactor (열천칭과 유동층반응기에서 석탄과 Petroleum Coke의 수증기 가스화반응)

  • Ji, Keunho;Song, Byungho
    • Korean Chemical Engineering Research
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    • v.50 no.6
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    • pp.1015-1020
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    • 2012
  • Lignite of low rank coal and petroleum coke of high sulfur content can be high potential energy sources for coal gasification process because of their plentiful supply. The steam gasification of lignite, anthracite, and pet coke has been carried out in both an atmospheric thermobalance reactor and a lab-scale fludized bed reactor (0.02 m i.d. ${\times}$ 0.6 m height). The effects of gasification temperature ($600{\sim}900^{\circ}C$) and partial pressure of steam (0.15~0.95 atm) on the gasification rate and on the heating value of product gas have been investigated. The modified volumetric reaction model was applied to the experimental data to describe the behavior of carbon conversion, and to evaluate kinetic parameters of char gasification. The results shows that higher temperature bring more hydrogen in the product syngas, and thus increased gas heating value. The feed rate of steam is needed to be optimized because an excess steam input would lower the gasification temperature which results in a degradation of fuel quality. The rank of calorific value of the product gas was anthracite > lignite > pet coke. Their obtained calorific value at $900^{\circ}C$ with 95% steam feed were 10.0 > 6.9 > 5.7 $MJ/m^3$. This study indicates that lignite and pet coke has a potential in fuel gas production.

Influencing Factors on the Lending Intention of Online Peer-to-Peer Lending: Lessons from Renrendai.com (온라인 P2P 대출의도의 영향요인에 관한 연구: 런런다이 사례를 중심으로)

  • Yang, Qin;Lee, Young-Chan
    • The Journal of Information Systems
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    • v.25 no.2
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    • pp.79-110
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    • 2016
  • Purpose Online Peer-to-peer lending (hereafter P2P lending), is a new method of lending money to unrelated individuals through an online financial intermediary. Usually in the online P2P transaction, individuals who would like to borrow money (hereafter borrowers) and those who would like to lend money (hereafter lenders) have no previous relationship. Based on enormous previous studies, this study develops an integrated model, particularly for the online P2P lending environment in China, to better understand the critical factors that influence lenders' intention to lend money through the online P2P lending platform. Design/methodology/approach In order to verify the hypotheses, we develop a questionnaire with 42 survey items. We measured all the items on a five-point Likert-type scale. We use Sojump.com to collect questionnaire and gather 246 valid responses from registered members of Renrendai.com. We analyzed the main survey data by using SPSS 18.0 and AMOS 20.0. We first estimated the reliability, validity, composite reliability and AVE and then conduct common method bias test. The mediating role of trust in platform and in borrower has been tested. Last we tested the hypotheses through the structural model. Findings The results reveal that service quality, information quality, structural assurance, awareness and reputation significantly impact lenders' trust in the online P2P lending platform. Second, awareness, reputation and perceived risk significantly impact lenders' trust in borrower and lending intention. Third, trust propensity has a positive effect on lenders' trust on borrower. Last, awareness, reputation, perceived risk, platform trust and borrower trust can directly impact lenders' lending intention.

Clinical Observation of Acupuncture and Nerve Block Treatment for Adhesive Capsulitis Patients (유착성 관절낭염에 대한 침 및 신경차단술 처치의 임상적 관찰)

  • Nam, Dong-Woo;Lim, Sabina;Kim, Jong-In;Kim, Keon-Sik;Lee, Doo-Ik;Lee, Jae-Dong;Lee, Yun-Ho;Choi, Do-Young
    • Journal of Acupuncture Research
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    • v.24 no.4
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    • pp.143-155
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    • 2007
  • Objectives: To observe the effect of acupuncture and nerve block combination treatment on adhesive capsulitis patients. Methods : 59 voluntary patients were randomly assigned to acupuncture treatment group(E group, n=22), nerve block treatment group(W group, n=17) and acupuncture and nerve block combination treatment group(EW group, n=20). The E group received acupuncture treatment on LI15, $TE_{14}$, $GB_{21}$ and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. The EW group received the same treatment as the W group and after 5minutes of rest, successively received the treatment identical to that of E group. All three groups were instructed to practice groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after 1, 2, 3 and 4week treatment. Constant Shoulder Assessment(CSA), Shoulder Pain and Disability Index(SPADI), Range of Motion(ROM), the patient's treatment satisfaction measured by Visual Analogue Scale(VAS) and Digital Infrared Thermographic Imaging(DITI) were used as assessment tools. The obtained data were analyzed and compared. Results : The E group showed significant improvement(p<0.05) on CSA, SPADI, VAS and DITI. As for ROM, Adduction and Extension improved significantly(p<0.05). The W group showed significant improvement(p<0.05) on CSA, SPADI, VAS and DITI. As for ROM, Abduction and Extension improved significantly. The EW group showed significant improvement(p<0.05) on CSA, SPADI and VAS. As for ROM, Adduction, Abduction, Extension and Flexion improved significantly. The improvement of CSA, VAS and Abduction ROM in the EW group was significantly(p<0.05) superior compared to the groups treated with single type of treatment. Conclusion : It is suggested that acupuncture and nerve block combination treatment for adhesive capsulitis patients is more effective than the two single treatments. Through further studies, the acupuncture and nerve block combination treatment model may be developed into East-West Collaboration Model in treating adhesive capsulitis.

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A Convergence Study on the Factors Influencing Nursing Students' Attitudes toward Standard Precautions: Focusing on the Health Belief Model (간호대학생의 표준주의 태도에 미치는 영향 요인에 관한 융합적 연구 : 건강신념모델 기반)

  • Kim, Mi-Ja;Yun, Seon-Jin
    • Journal of the Korea Convergence Society
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    • v.9 no.6
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    • pp.77-88
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    • 2018
  • "Standard Precautions" (SP) is important for nursing students as it will lead to the protection of health professionals from infectious diseases and prevention of the wide spread of epidemic illnesses. Therefore, this study investigated factors influencing nursing students' attitudes toward SP. Data were collected from 291 nursing students from May to June, in 2016. According to the results, perceived benefit (4.26) was the highest among sub factors of the health belief model, test score of SP was 78.8%, and attitude score (4 point scale) was 3.63. Perceived sensitivity, perceived benefits, perceived barriers, self-efficacy, knowledge about SP showed significant correlations with the attitudes towards SP. Among sub-factors of the health beliefs, perceived sensitivity (${\beta}=.152$, p<.05) and perceived barrier (${\beta}=-.125$, p<.05) were found to influence nursing students' attitudes toward SP (F= 5.680, p<.001). Hence, it can be concluded that a convergence education program promoting health belief is needed for improving attitudes toward SP among nursing students.

Dispersion in the Unsteady Separated Flow Past Complex Geometries (복합지형상에서 비정상 박리흐름에 의한 확산)

  • Ryu, Chan-Su
    • Journal of the Korean earth science society
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    • v.22 no.6
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    • pp.512-527
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    • 2001
  • Separated flows passed complex geometries are modeled by discrete vortex techniques. The flows are assumed to be rotational and inviscid, and a new techlnique is described to determine the stream functions for linear shear profiles. The geometries considered are the snow cornice and the backward-facing step, whose edges allow for the separation of the flow and reattachment downstream of the recirculation regions. A point vortex has been added to the flows in order to constrain the separation points to be located at the edges, while the conformal mappings have been modified in order to smooth the sharp edges and to let the separation points free to oscillate around the points of maximum curvature. Unsteadiness is imposed to the flow by perturbing the vortex location, either by displacing the vortex from the equilibrium, or by imposing a random perturbation with zero mean to the vortex in equilibrium. The trajectories of passive scalars continuously released upwind of the separation point and trapped by the recirculating bubble are numerically integrated, and concentration time series are calculated at fixed locations downwind of the reattachment points. This model proves to be capable of reproducing the trapping and intermittent release of scalars, in agreement with the simulation of the flow passed a snow cornice performed by a discrete multi-vortex model, as well as with direct numerical simulations of the flow passed a backward-facing step. The results of simulation indicate that for flows undergoing separation and reattachment the unsteadiness of the recirculating bubble is the main mechanism responsible for the intense large-scale concentration fluctuations downstream.

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