• 대한안전경영과학회지
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• 제18권1호
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• pp.17-24
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• 2016

Many fatal and non-fatal injuries occurred as a result of unexpected falls from horse scaffolds during structural or finishing works such as painting, plastering, or plumbing. Therefore, this study is to improve safety standards for horse scaffolds used mostly in the interior finishing works. But hazard elements for the horse scaffolds has not been specifically identified. This study has analyzed the accidents of horse scaffolds to prevent construction accidents and the characteristics of a serious accidents related the horse scaffolds. It was suggested a safety management plan and a group of accidents characteristics. The results of this study are expected to be utilized as basic data for prviding a reference related to the horse scaffolds and to be unified the regulations associated with the horse scaffolds.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2000년도 추계학술발표대회 및 bio-venture fair
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• pp.421-424
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• 2000

Cartilage injuries are frequent nowadays. The previous surgical treatment of cartilage defect was limited. Another approach in the treatment of cartilage injuries is the use of reconstitute cartilage consisting of chondrocytes cultured in suitable biodegradable scaffolds. Current studies have demonstrated the compatibility of chondrocytes with different biomaterials and the chondrogenesis in various types of porous scaffolds. The cell ingrowth into the porous scaffolds is modulated by initial cell loading efficiency. Therefore, well-interconnected pore structure and even pore distribution of the scaffolds are essential for efficient cell seeding. According to our previous work, well-interconnected macroporous scaffolds can be prepared by gas-foaming/salt-leaching method using ammonium bicarbonate salt as porogen additives. In this work, primary chondrocytes were cultured in PLGA 65/35 scaffolds fabricated by using our method. Cells seeded in the scaffolds showed well distribution by agitated seeding method. Histochemical staining of proteoglycans present in the scaffolds was used to visualize the chondrocyte ingrowth in the scaffolds. At 3 weeks, the population of chondrocytes was increased for the most part of the scaffolds, and extra cellular matrix (ECM) secretion was increased as culture periods progressed.

• Steel and Composite Structures
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• 제4권6호
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• pp.471-487
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• 2004

Modular steel scaffolds are commonly used as supporting scaffolds in building construction, and traditionally, the load carrying capacities of these scaffolds are obtained from limited full-scale tests with little rational design. Structural failure of these scaffolds occurs from time to time due to inadequate design, poor installation and over-loads on sites. In general, multi-storey modular steel scaffolds are very slender structures which exhibit significant non-linear behaviour. Hence, secondary moments due to both $P-{\delta}$ and $P-{\Delta}$ effects should be properly accounted for in the non-linear analyses. Moreover, while the structural behaviour of these scaffolds is known to be very sensitive to the types and the magnitudes of restraints provided from attached members and supports, yet it is always difficult to quantify these restraints in either test or practical conditions. The problem is further complicated due to the presence of initial geometrical imperfections in the scaffolds, including both member out-of-straightness and storey out-of-plumbness, and hence, initial geometrical imperfections should be carefully incorporated. This paper presents an extensive numerical study on three different approaches in analyzing and designing multi-storey modular steel scaffolds, namely, a) Eigenmode Imperfection Approach, b) Notional Load Approach, and c) Critical Load Approach. It should be noted that the three approaches adopt different ways to allow for the non-linear behaviour of the scaffolds in the presence of initial geometrical imperfections. Moreover, their suitability and accuracy in predicting the structural behaviour of modular steel scaffolds are discussed and compared thoroughly. The study aims to develop a simplified and yet reliable design approach for safe prediction on the load carrying capacities of multi-storey modular steel scaffolds, so that engineers can ensure safe and effective use of these scaffolds in building construction.

• 한국안전학회지
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• 제32권3호
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• pp.66-73
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• 2017

This study examined the structural behavior of bracket scaffolds reflecting the influence of bracket's deflection. Even though the supporting condition of bracket scaffolds is different to that of general earth-supported scaffolds, there is no clear standards about the installation of bracket scaffolds. To compare the structural behaviors of the earth-supported scaffolds without settlements in columns and those of bracket scaffolds installed on the bracket structure, the finite element analysis was performed. The results show that the differential settlement between the scaffold columns installed on the bracket was occurred due to the deflection of the bracket. The differential settlement gave birth to remarkable secondary stress to the scaffold columns. It is resonable to locate all scaffold columns on the brackets, and if unavoidable situation is faced at a site, the horizontal members should not placed alone without columns on the brackets. Moreover, the structural analysis should be performed to ensure structural safety of bracket scaffolds before installation. In addition, the location of wall connection to the structures is recommended to the scaffolds columns installed on the brackets.

• Steel and Composite Structures
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• 제4권3호
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• pp.211-226
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• 2004

This paper presents a study on the structural behaviour of modular steel scaffolds through both experimental and numerical investigations. Three one-storey and three two-storey modular steel scaffolds were built and tested to failure in order to examine the structural behaviour of typical modular steel scaffolds. Details of the tests and their test results were presented in this paper. Moreover, an advanced non-linear analysis method was employed to evaluate the load carrying capacities of these scaffolds under different support conditions. Comparisons between the experimental and the numerical results on the structural behaviour of these modular steel scaffolds were also presented. Moreover, the restraining effects of external supports in practical situations were also studied through finite element methods. The predicted load carrying capacities and deformations at failure of these models under partially restrained conditions were found to be close to the experimental results. A codified design method for column buckling with modified slenderness ratios was adopted for practical design of modular steel scaffolds.

• 국제학술발표논문집
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• The 6th International Conference on Construction Engineering and Project Management
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• pp.255-258
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• 2015

Scaffolds are frequently used in construction projects. Despite the impact on the entire safety, scaffolds are rarely analyzed as part of the safety planning. While recent advances in BIM (Building Information Modeling) provides opportunity to address potential safety issues in the early planning stages, it is still labor-intensive and challenging to incorporate scaffolds into current manual jobsite safety analysis which is time-consuming and error-prone. Consequently, potential safety hazards related to scaffolds are identified and presented during the construction phase. The objective of this research is to integrate scaffolds into automated safety analysis using BIM. A safety checking system was created to simulate the movements of scaffolds along the paths of crews using the scaffolds. Algorithms in the system automatically identify safety hazards related to activities working on scaffolds. Then, the system was implemented in a commercially available BIM software program for case studies. The results show that the algorithms successfully identified safety hazards that were not noticed by project managers of the projects. The results were visualized in BIM to facilitate early safety communications.

• Tissue Engineering and Regenerative Medicine
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• 제15권6호
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• pp.673-697
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• 2018

BACKGROUND: Cartilage tissue engineering (CTE) aims to obtain a structure mimicking native cartilage tissue through the combination of relevant cells, three-dimensional scaffolds, and extraneous signals. Implantation of 'matured' constructs is thus expected to provide solution for treating large injury of articular cartilage. Type I collagen is widely used as scaffolds for CTE products undergoing clinical trial, owing to its ubiquitous biocompatibility and vast clinical approval. However, the long-term performance of pure type I collagen scaffolds would suffer from its limited chondrogenic capacity and inferior mechanical properties. This paper aims to provide insights necessary for advancing type I collagen scaffolds in the CTE applications. METHODS: Initially, the interactions of type I/II collagen with CTE-relevant cells [i.e., articular chondrocytes (ACs) and mesenchymal stem cells (MSCs)] are discussed. Next, the physical features and chemical composition of the scaffolds crucial to support chondrogenic activities of AC and MSC are highlighted. Attempts to optimize the collagen scaffolds by blending with natural/synthetic polymers are described. Hybrid strategy in which collagen and structural polymers are combined in non-blending manner is detailed. RESULTS: Type I collagen is sufficient to support cellular activities of ACs and MSCs; however it shows limited chondrogenic performance than type II collagen. Nonetheless, type I collagen is the clinically feasible option since type II collagen shows arthritogenic potency. Physical features of scaffolds such as internal structure, pore size, stiffness, etc. are shown to be crucial in influencing the differentiation fate and secreting extracellular matrixes from ACs and MSCs. Collagen can be blended with native or synthetic polymer to improve the mechanical and bioactivities of final composites. However, the versatility of blending strategy is limited due to denaturation of type I collagen at harsh processing condition. Hybrid strategy is successful in maximizing bioactivity of collagen scaffolds and mechanical robustness of structural polymer. CONCLUSION: Considering the previous improvements of physical and compositional properties of collagen scaffolds and recent manufacturing developments of structural polymer, it is concluded that hybrid strategy is a promising approach to advance further collagen-based scaffolds in CTE.

• 한국재료학회지
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• 제17권11호
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• pp.622-627
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• 2007

Porous poly(e-caprolactone) (PCL) scaffolds were fabricated by salt leaching method. The PCL scaffolds were treated with aqueous NaOH for 0h, 2h, 4h, 8h, and 12h at $40^{\circ}C$. The NaOH-treated PCL scaffolds were dipped in $CaCl_2$ and $K_2HPO_4{\cdot}_3H_2O$ solution alternately three times to induce apatite nuclei onto the surface of the scaffolds. The NaOH-treated PCL scaffolds were immersed into SBF solution for 1day to grow the apatite. The apatite formation were investigated as a fuction of NaOH treatment time. The hydrophilicty and surface area of the PCL scaffolds were increased with NaOH-treatment time. The NaOH-treated PCL scaffolds were successfully formed a dense and uniform bone-like apatite layer after immersion for 1 day in SBF solution.

• 한국기계가공학회지
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• 제21권4호
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• pp.70-76
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• 2022

Calcium-phosphate-based bioceramics are promising biomaterials for scaffolds because they can assist in bone regeneration. In this study, a laser sintering deposition system was developed, and 3D hydroxyapatite (HA) scaffolds were fabricated. The main process conditions of the HA scaffolds were laser power, table velocity, and laser focal distance. As the laser power increased, the line width, line height, and layer thickness also increased. Further, the line width, line height, and layer thickness decreased as the table velocity increased. As the laser focal distance increased, the line width increased, but the line height and layer thickness decreased. The fabricated green scaffolds were sintered at 1050 ℃ and 1150 ℃. The sintered scaffolds had a uniform and continuous interconnected shape, with pore sizes ranging from 850 to 950 ㎛ having 53% porosity. The compressive strength of the scaffolds decreased from 0.72 MPa (1050 ℃) to 0.53 MPa (1150 ℃). The biocompatibility of the scaffolds was investigated by analyzing the adhesion of osteoblast-like MG-63 cells cultured on the surfaces of the scaffolds. The results indicate that the scaffold sintered at 1050 ℃ had good mechanical and biological properties compared to that at 1150 ℃.

• 한국축산식품학회지
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• 제44권2호
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• pp.269-283
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• 2024

Cultured meat is one of the research areas currently in the spotlight in the agricultural and livestock industry, and refers to cells obtained from livestock that are proliferated and differentiated and processed into edible meat. These cell-cultured meats are mainly studied at the lab-scale by culturing them in flasks, and for commercial use, they are produced using scaffolds that mimic cell supports. Scaffolds are broadly divided into fiber scaffolds, hydrogels, and micro-carrier beads, and these are classified according to processing methods and materials. In particular, a scaffold is essential for mass production, which allows it to have appearance, texture, and flavor characteristics similar to meat. Because cultured meat is cultured in a state where oxygen is blocked, it may be lighter in color or produce less flavor substances than edible meat, but these can be compensated for by adding natural substances to the scaffolds or improving fat adhesion. In addition, it has the advantage of being able to express the texture characteristics of the scaffolds that make up the meat in various ways depending on the materials and manufacturing methods of the scaffolds. As a result, to increase consumers' preference for cultured meat and its similarity to edible meat, it is believed that manufacturing scaffolds taking into account the characteristics of edible meat will serve as an important factor. Therefore, continued research and interest in scaffolds is believed to be necessary.