Journal of the Korean Society of Manufacturing Process Engineers (한국기계가공학회지)

The Korean Society of Manufacturing Process Engineers (한국기계가공학회)
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A Study on Fabrication of 3D Hydroxyapatite Scaffolds Using a Laser Sintering Deposition System

레이저 소결 적층 시스템을 이용한 3차원 수산화인회석 인공지지체 제작에 관한 연구

  • 최승혁 (경북대학교 기계공학과) ;
  • 사민우 (에스제이티 기업부설연구소) ;
  • 김종영 (안동대학교 기계공학과)
  • Received : 2021.09.07
  • Accepted : 2021.12.09
  • Published : 2022.04.30
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Abstract

Calcium-phosphate-based bioceramics are promising biomaterials for scaffolds because they can assist in bone regeneration. In this study, a laser sintering deposition system was developed, and 3D hydroxyapatite (HA) scaffolds were fabricated. The main process conditions of the HA scaffolds were laser power, table velocity, and laser focal distance. As the laser power increased, the line width, line height, and layer thickness also increased. Further, the line width, line height, and layer thickness decreased as the table velocity increased. As the laser focal distance increased, the line width increased, but the line height and layer thickness decreased. The fabricated green scaffolds were sintered at 1050 ℃ and 1150 ℃. The sintered scaffolds had a uniform and continuous interconnected shape, with pore sizes ranging from 850 to 950 ㎛ having 53% porosity. The compressive strength of the scaffolds decreased from 0.72 MPa (1050 ℃) to 0.53 MPa (1150 ℃). The biocompatibility of the scaffolds was investigated by analyzing the adhesion of osteoblast-like MG-63 cells cultured on the surfaces of the scaffolds. The results indicate that the scaffold sintered at 1050 ℃ had good mechanical and biological properties compared to that at 1150 ℃.

Keywords

Acknowledgement

이 논문은 안동대학교 기본연구지원사업에 의하여 연구되었음.

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