• Journal of Acupuncture Research
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• 제20권3호
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• pp.131-140
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• 2003

Objective : The purpose of this study is to investigate the effect of Panax ginseng Radix herb-acupuncture on c-fos expression in each area of the hippocampus of acutely ethanol-intoxicated rats. Methods : Twenty-four male Sprague-Dawley tats were divided into untreated(normal), ethanol-treated(control), Panax ginseng Radix-treated(sample A), ethanol-and Panax gingseng Radix-treated(sample B) groups. Each group was evaluated by the changes of c-fos-positive neurons in each area of the hippocampus by using and image analyzer and microscope. Results : 1. In the CA1 area, the number of c-fos-positive neurons in the control group was diminished compared with the normal group. The number of c-fos-positive neurons in the sample B group had no marked difference from the control group. 2. In the CA2-3 area, the number of c-fos-positive neurons in the control group was diminished compared with the normal group, The number of c-fos-positive neurons in the sample B group was increased compared with the control group. 3. In the Dentate gyrus area, the number of c-fos-positive neurons in the control group was diminished compared with the normal group. The number of c-fos-positive neurons in the sample B group was increased compared with the control group. Conclusions : These results indicate that, c-fos expression in each area of the hippocampus was reduced in ethanol-intoxicated group. Treatment of Panax ginseng Radix herb-acupuncture increased this diminution. Panax ginseng Radix could be able to effect on the prevention of the amnesia and learning disability in alcoholism.

• 대한산업공학회지
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• 제3권2호
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• pp.99-106
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• 1977

A double sampling procedure with zero acceptance number for the first sample whose operating characteristic closely matches that of a given single sampling plan and whose combined sample size does not exceed that of the given single sampling plan is proposed. The proposed double sampling plans corresponding to the MIL-STD-105D plans are tabulated and it is found that their ASN's are considerably smaller than those of corresponding MIL-STD-105D single or double sampling plans.

• 소음진동
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• 제8권5호
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• pp.814-820
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• 1998

Vibration data from two blasting sites were analyzed to determine the sufficient sample number for blasting vibration estimation. Most important result is that much more than 30 sample data and succeeding measurement are necessary to estimate confident blasting vibration level and to determine limit scaled distance.

• Communications for Statistical Applications and Methods
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• 제8권2호
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• pp.383-394
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• 2001

This paper is a generalization of single and two-level skip-lot sampling plans to n-level. On every skipping inspection of the n-level skip-lot sampling plan, not only the number of consecutive lots to be accepted but also the fraction of lots to be inspected can be freely choosed. The general formulas of the operating characteristic function, average fraction inspected, average sample number and average outgoing quality in n-level skip-lot sampling plan are derived. The operating characteristic curves, average sample number and average outgoing quality of a reference plan, two-level and five-level skip-lot sampling plans are compared.

• 한국임상수의학회지
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• 제28권4호
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• pp.422-426
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• 2011

For a national survey in which wide geographic region or an entire country is targeted, multi-stage sampling approach is widely used to overcome the problem of simple random sampling, to consider both herd- and animallevel factors associated with disease occurrence, and to adjust clustering effect of disease in the population in the calculation of sample size. The aim of this study was to establish sample size for estimating bovine tuberculosis (TB) in Korea using stratified two-stage sampling design. The sample size was determined by taking into account the possible clustering of TB-infected animals on individual herds to increase the reliability of survey results. In this study, the country was stratified into nine provinces (administrative unit) and herd, the primary sampling unit, was considered as a cluster. For all analyses, design effect of 2, between-cluster prevalence of 50% to yield maximum sample size, and mean herd size of 65 were assumed due to lack of information available. Using a two-stage sampling scheme, the number of cattle sampled per herd was 65 cattle, regardless of confidence level, prevalence, and mean herd size examined. Number of clusters to be sampled at a 95% level of confidence was estimated to be 296, 74, 33, 19, 12, and 9 for desired precision of 0.01, 0.02, 0.03, 0.04, 0.05, and 0.06, respectively. Therefore, the total sample size with a 95% confidence level was 172,872, 43,218, 19,224, 10,818, 6,930, and 4,806 for desired precision ranging from 0.01 to 0.06. The sample size was increased with desired precision and design effect. In a situation where the number of cattle sampled per herd is fixed ranging from 5 to 40 with a 5-head interval, total sample size with a 95% confidence level was estimated to be 6,480, 10,080, 13,770, 17,280, 20.925, 24,570, 28,350, and 31,680, respectively. The percent increase in total sample size resulting from the use of intra-cluster correlation coefficient of 0.3 was 22.2, 32.1, 36.3, 39.6, 41.9, 42.9, 42,2, and 44.3%, respectively in comparison to the use of coefficient of 0.2.

• 한국식품영양과학회지
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• 제24권6호
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• pp.990-997
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• 1995

Effect of preparation method on Yulmoo kimchi(watery kimchi prepared with Yulmoo, leaf radish) fermentation was investigated by measuring physicochemical, microbiological and sensory properties for 20 days. Yulmoo kimchi was fermented at 4$^{\circ}C$ after keeping at room temperature(27$\pm$0.5$^{\circ}C$) for 8 hours. Four types(A, B, C, D) of Yulmoo kimchi were prepared. Sample A was made without wheat flour paste and red pepper powder and sample B was made with wheat flour paste. Sample C was made with red pepper powder, and sample D was made with wheat flour paste and red pepper powder. pH was slowly lowered and stabled after 10 days in all samples. Total acid content increased in all samples. Reducing sugar content initially increased and decreased thereafter. Especially, reducing sugar content of sample B increased in the early stage of fermentation and maintained initial reducing sugar content after 20 days. Total vitamin C content reduced during fermentation in all samples. Especially initial total vitamin C content of sample D increased more than those of other samples relatiely. Lightness and yellowness showed no difference, but on the other hand redness increased gradually in all samples. The number of lactic acid bactgeria reached maximum value in 10~13 days with the total cell numbers and gradually decreased thereafter in all samples. The number of lactic acid bacteria and total cell number of sample D was much more than those of any other samples. As a result of the sensory evaluation, Yulmoo kimchi showed significant difference in all characteristics. Sample D showed the highest scores in all characteristics before 10 days of fermentation. However, after 10 days sample B showed the highest scores.

• Journal of Acupuncture Research
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• 제17권1호
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• pp.251-286
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• 2000

To study the effects of anti-cancer, anti-metastasis and immune response improvement of aqua-acupuncture with Cistanches Herba infusion solution, we used Cistanches Herba infusion solution(taken by water-alcohol method) put into Chung-wan(CV12) and Chok-Samni(S36) of BALB/c or C57BL/6 which are corresponding to human body. We observed the cytotoxicity, the effect on the expression of MMP-9 gene, the ability to control cancer cell proliferation, change of body weight, surviving number, MST, ILS, changes in amount of WBC, RBC, PLT, total protein, creatinine, glucose and LDH, weight of spleen, number of pulmonary colony, histological analysis on tissue metastasis of lung and liver, splenic cell proliferation, the expression of cytokine gene, the number of $CD4^+$, $CD8^+$, $CD19^+$ and NK cell, and concluded like this. The results were obtained as follows : 1. The cytotoxicity about B16-F10 cell line of $2^0$, $2^{-1}$, $2^{-2}$, $2^{-5}$ diluent groups in Cistanches Herba infusion solution treatment was inhibited significantly, compared with control group. 2. The cytotoxicity about HT1080 cell line of $2^0$, $2^{-1}$, $2^{-2}$, $2^{-3}$, $2^{-5}$, $2^{-8}$ diluent groups in Cistanches Herba infusion solution treatment was inhibited significantly, compared with control group. 3. The effect on expression of MMP-9 gene was decreased in all the sample groups, compared with control group. 4. The effect on the control-ability on the cancer cell proliferation showed cytotooicity significantly in $2^0$, $2^{-1}$, $2^{-2}$, $2^{-3}$, $2^{-4}$, $2^{-5}$ diluent groups. 5. S-180 cancer cell line transplants in BALB/c mice were inhibited significantly in weight increase in all the sample groups, compared with control group. The surviving number increased in almost sample groups, except one group put into Chok-Samni(S36) with 20% Cistanches Herba infusion solution treatment group that showed same number of the control group. 6. S-180 cancer cell line transplants in BALB/c mice showed high MST and ILS significantly in almost sample groups, compared with control group. But one group put into Chok-Samni(S36) with 20% Cistanches Herba infusion solution treatment group showed low MST and ILS than control group. 7. The sample group injected in vein with B16-F10 cancer cell line in C57BL/6 mice showed increased ILS compared with control group significantly in anti-metastasis test. 8. The sample group injected in vein with B16-F10 cancer cell line in C57BL/6 mice were increased significantly in the number of WBC and glucose, and decreased significantly in the amount of LDH, compared with control group. However, there's no significant increase or decrease in number of RBC, PLT, total protein and creatinine. 9. We couldn't find any significant relation in spleen weight of the sample group. 10. In pulmonary colony, sample group was decreased significantly, compared with control group. 11. Histological analysis of sample group inhivited compared with that of control group in both of lung and liver. 12. In immune system, all the sample groups showed having more relevancy to the effect on splenic cell proliferation than normal group. 13. The effect on cytokine gene expression of all the sample groups were increased than control group. 14. In flow cytometry there's no significant relation in number of $CD8^+$, $CD19^+$ cell, however, the number of $CD4^+$ cell and NK cell in sample groups were increased than in control group. Above the results showed that aqua-acupuncture of Cistanches Herba infusion solution has effects of anti-cancer, anti-metastasis and immune response improvement.

• Communications for Statistical Applications and Methods
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• 제19권3호
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• pp.315-331
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• 2012

2011년 3월 오프라인 노래연습장, 유흥 단란주점 표본조사업소에서 수집한 곡목별 히팅수 로그데이터로부터 강남지부 등 총 11개 지부의 히팅수와 히팅수 표본오차를 추정하였다. 업소에서 징수한 음악저작물 사용료를 추정된 곡목별 히팅수를 기준으로 관계권리자(작곡, 작사, 편곡자 등)에게 분배하는 현행 분배방식에 따라 표본오차 규모를 금액으로 환산하여 크기를 검토하였다. 기존표본은 과소하여 히팅수 추정시 표본오차를 과다하게 발생시켰으며, 본 연구에서는 히팅수 추정오차를 줄여 음악저작권사용료 분배에 형평성을 기할 수 있는 합리적인 표본크기 개선방안을 제안하였다.

• 대한산업공학회지
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• 제30권3호
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• pp.205-212
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• 2004

This paper proposes the variables repetitive group sampling plan where the quality characteristic following normal distribution has upper or lower specification limit. The problem is formulated as a non-linear programming problem where the objective function to minimize is the average sample number and the constraints are related to lot acceptance probabilities at acceptable quality level (AQL) and limiting quality level (LQL) under the operating characteristic curve. Sampling plan tables are constructed for the selection of parameters indexed by AQL and LQL in the cases of known standard deviation and unknown standard deviation. It is shown that the proposed sampling plan significantly reduces the average sample number as compared with the single or the double sampling plan.

• Communications for Statistical Applications and Methods
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• 제16권5호
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• pp.763-779
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• 2009

노래 연습장에서 연주되는 노래곡목별 히팅수를 정확하게 추정하기 위한 표본설계에서는 조사모집단 정의와 층화방안을 연구하고 기존데이터를 분석하여 표본크기를 산출한 후에 표본배분방법을 연구하였다. 표본설계에 의해서 선정된 표본업소들의 대표성을 온라인 노래연습장의 로그데이터를 이용하여 모수추정치의 오차를 분석하여 검토하였다. 오프라인 노래 연습장의 모수추정법을 제안하고 실제로 수집한 로그데이터로부터 모수추정치를 계산하여 온라인과 오프라인 노래연습장에서 연주되는 노래곡목별 히팅수에서 많이 차이가 있음을 보였다. 온라인과 오프라인 노래연습장의 특성차이를 반영한 분배방법의 개선안을 제안하고 비교분석을 통해서 최적 분배방법을 선정하였다.