• 대한전자공학회논문지TE
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• 제37권3호
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• pp.30-36
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• 2000

본 논문에서는 결함신호의 신호 대 잡음비를 높이기 위해 최소진복선택 알고리즘과 극 문턱치(PT : polarity threshold) 알고리즘을 결합한 최소극 문턱치(MPO : minimum polarity threshold) 알고리즘을 이용한 원전 고감쇠 용접부 초음파 검사방법을 제안하였다. 제안된 알고리즘의 유용성을 확인하기 위한 실험에서는 ASME Xl 코드에 준하는 원전의 실제 모재와 동일한 용접방법으로 제작된 대비 시험편과 4종류의 개선된 탐촉자를 이용하였다. 실험 결과, SE(safeend)와 CCSS(centrifugal casting stainless steel) 재료는 조직의 구조적 특성 때문에 산란신호가 발생하고, 용접 내부에서는 높은 감쇠 현상이 발생하여 정확한 결합검출 능력이 저하되며, 이러한 결함신호에 최소극 문턱치 알고리즘을 적용하면 신호 대 잡음비가 2.6배 개선됨을 확인하였다.

• Journal of Microbiology and Biotechnology
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• 제20권10호
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• pp.1463-1470
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• 2010

E. coli has long been widely used as a host system for the manufacture of recombinant proteins intended for human therapeutic use. When considering the impurities to be eliminated during the downstream process, residual host cell DNA is a major safety concern. The presence of residual E. coli host cell DNA in the final products is typically determined using a conventional slot blot hybridization assay or total DNA Threshold assay. However, both the former and latter methods are time consuming, expensive, and relatively insensitive. This study thus attempted to develop a more sensitive real-time PCR assay for the specific detection of residual E. coli DNA. This novel method was then compared with the slot blot hybridization assay and total DNA Threshold assay in order to determine its effectiveness and overall capabilities. The novel approach involved the selection of a specific primer pair for amplification of the E. coli 16S rRNA gene in an effort to improve sensitivity, whereas the E. coli host cell DNA quantification took place through the use of SYBR Green I. The detection limit of the real-time PCR assay, under these optimized conditions, was calculated to be 0.042 pg genomic DNA, which was much higher than those of both the slot blot hybridization assay and total DNA Threshold assay, where the detection limits were 2.42 and 3.73 pg genomic DNA, respectively. Hence, the real-time PCR assay can be said to be more reproducible, more accurate, and more precise than either the slot blot hybridization assay or total DNA Threshold assay. The real-time PCR assay may thus be a promising new tool for the quantitative detection and clearance validation of residual E. coli host cell DNA during the manufacturingprocess for recombinant therapeutics.

• Corrosion Science and Technology
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• 제20권4호
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• pp.210-229
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• 2021

To safely operate domestic nuclear power plants approaching the end of their design life, the material degradation management strategy of the components is important. Among studies conducted to improve the soundness of nuclear reactor components, research methods for understanding the degradation of reactor internals and preparing management strategies were surveyed. Since the IGSCC (Intergranular Stress Corrosion Cracking) initiation and propagation process is associated with metal dissolution at the crack tip, crack initiation sensitivity was decreased in the hydrogenated water with decreased crack sensitivity but occurrence of small surface cracks increased. A stress of 50 to 55% of the yield strength of the irradiated materials was required to cause IASCC (Irradiation Assisted Stress Corrosion Cracking) failure at the end of the reactor operating life. In the threshold-stress analysis, IASCC cracks were not expected to occur until the end of life at a stress of less than 62% of the investigated yield strength, and the IASCC critical dose was determined to be 4 dpa (Displacement Per Atom). The stainless steel surface oxide was composed of an internal Cr-rich spinel oxide and an external Fe and Ni-rich oxide, regardless of the dose and applied strain level.

• 대한원격탐사학회지
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• 제32권4호
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• pp.339-351
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• 2016

For the safety of sea, it is important to monitor sea fog, one of the dangerous meteorological phenomena which cause marine accidents. To detect and monitor sea fog, Moderate Resolution Imaging Spectroradiometer (MODIS) data which is capable to provide spatial distribution of sea fog has been used. The previous automatic sea fog detection algorithms were focused on detecting sea fog using Terra/MODIS only. The improved algorithm is based on the sea fog detection algorithm by Wu and Li (2014) and it is applicable to both Terra and Aqua MODIS data. We have focused on detecting spring season sea fog events in the Yellow Sea. The algorithm includes application of cloud mask product, the Normalized Difference Snow Index (NDSI), the STandard Deviation test using infrared channel ($STD_{IR}$) with various window size, Temperature Difference Index(TDI) in the algorithm (BTCT - SST) and Normalized Water Vapor Index (NWVI). Through the calculation of the Hanssen-Kuiper Skill Score (KSS) using sea fog manual detection result, we derived more suitable threshold for each index. The adjusted threshold is expected to bring higher accuracy of sea fog detection for spring season daytime sea fog detection using MODIS in the Yellow Sea.

• 한국안전학회지
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• 제21권4호
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• pp.19-24
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• 2006

Fatigue crack propagation tests for the brake disc cast iron were conducted for investigating fatigue crack propagation rate(da/dN), crack propagation path and fracture toughness($K_c$) of the material. The threshold stress intensity factor range, ${\Delta}K_{th}$, was found to be about $6MPa{\sqrt{m}}$ at the stress ratio of R = 0.1. Also, fracture toughness value was determined to be $24.7MPa{\sqrt{m}}$. Irregular fatigue fracture surfaces were observed, indicating that fatigue crack growth occurred at the interface between randomly scattered flak graphite and ferrite, where the interfacial strength was relatively weak.

• 한국안전학회지
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• 제24권1호
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• pp.89-94
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• 2009

The purpose of this study is to estimate the critical flood discharge and flash flood trigger rainfall for alarm system providing for a flash flood in mountainous area. The flash flood need non-linear approaching method, because rainfall-runoff is nonlinear and it is difficult to explain the existing linear rainfall-runoff. Hydrological characteristics would be utilized to apply such as hydrologic modelling or basin management. This study was effectively estimated a topographic characteristic factor of basin using the GIS. Especially, decided stream order using GIS at stream order decision that is important for input variable of GCIUH. A flash floods defined as a flood which follows shortly after a heavy or excessive rainfall event, with a few hours. In this study, we gave a definition that a critical flood for alarm is the flood when valley depth judging dangerous depth is over 0.5m depth from the bottom of channel. Result that calculate threshold discharge to use GCIUH, at the Mureung valley basin, flash flood trigger rainfall was 16.34mm in the first 20minutes when the threshold discharge was $14.54m^3/sec$.

• Nuclear Engineering and Technology
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• 제53권7호
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• pp.2348-2356
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• 2021

As a relatively new radiation imaging method, the cosmic-ray muon scattering imaging technology can be used to prevent nuclear smuggling and is of considerable significance to nuclear safety. Proposed in this paper is a new reconstruction algorithm based on density clustering, aiming to improve inspection quality with better performance. Firstly, this new algorithm is introduced in detail. Then in order to eliminate the inequity of the density threshold caused by the heterogeneity of the muon flux in different positions, a new flux correction method is proposed. Finally, three groups of simulation experiments are carried out with the help of Geant4 toolkit to optimize the algorithm parameters, verify the correction method and test the inspection quality under shielded condition, and compare this algorithm with another common inspection algorithm under different conditions. The results show that this algorithm can effectively identify and locate nuclear material with low misjudging and missing rates even when there is shielding and momentum precision is low, and the threshold correcting method is universally effective for density clustering algorithms.

• 한국가스학회지
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• 제25권5호
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• pp.63-69
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• 2021

본 연구에서는 오토인코더의 재구성 오류의 임계값을 이용하여 가스 시설에서의 작업이 정상 작업인지 비정상 작업인지를 판단하는 알고리즘을 구축하였다. 이 알고리즘은 정상 작업의 시계열 데이터만으로 오토인코더를 학습하여 최적화된 정상 작업의 재구성 오류의 임계값을 도출한다. 이 알고리즘을 새로운 작업의 시계열 데이터에 적용하여 재구성 오류를 구한 다음 이것을 정상 작업의 재구성 오류 임계값과 비교하여 정상작업인지 비정상 작업인지를 판별한다. 이 알고리즘을 학습하고 검증하기 위해서 가상의 가스 시설에서의 작업을 규정하고 정상 작업 데이터로만 이루어진 학습 데이터 세트와 정상 작업과 비정상 작업 데이터를 모두 포함한 검증 데이터 세트를 구축하였다.

• 한국식품위생안전성학회지
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• 제21권1호
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• pp.9-13
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• 2006

Model system을 이용하여 설탕 수용액의 감미 역치를 구한 결과 0.4%였고, 저당물엿 및 환원물엿 등 감미원 혼합액의 감미 역치는 0.75-0.80%로 측정되었다. 각각의 감미 역치를 설탕에 대한 상대적 감미도로 환산 보정한 결과 0.64-0.67%였고, 이 역치를 설탕에 대한 감미로 환산하여 감미도를 산출하였다. 감미원 혼합액의 설탕에 대한 상대적 감미도 0-20 사이의 관계식은 $y=0.0038x^2-1.3171x+13.497,\;R^2=0.9736$(단, x=감미원의 상대적 감미도, y=역치, R=상관계수)로 계산되었다. 감미원별 역치를 이용하여 감미도를 계산한 결과 저당물엿과 환원물엿을 넣은 통팥앙금의 감미도는 설탕으로 제조된 것의 $55^{\circ}Brix$보다 낮은 32.78-34.32의 값을 나타내었다. 설탕과 식염의 감미에 대한 상승효과를 조사한 결과 0.4%와 1%설탕 수용액에 대해서는 감미의 상승효과가 나타나지 않았고, 2% 이상의 설탕 수용액에서는 식염을 0.05% 첨가했을 때 감미의 상승효과가 가장 높은 것으로 나타났다. 통팥앙금에 식염을 0.2% 첨가했을 때 유의성은 없었으나 다른 시료에 비해 감미가 상승하는 것으로 나타났다.

• 한국산업보건학회지
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• 제22권1호
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• pp.73-81
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• 2012

Object: The aim of this study is to suggest a list of priority chemicals for the Hazard & Risk Evaluation of Chemicals (HREC) controlled by the Industrial Safety and Health Act (ISHA). Method: Screening assessment was done for 642 chemicals whose exposure threshold limit values were set by the Ministry of Employment and Labor (MOEL). Hazard data were collected from Korea Occupational Safety & Health Agency (KOSHA) and/or other toxicity database. Exposure data were obtained from KOSHA internal database. The hazard and exposure scores of chemicals were listed by order of priority in accordance with GHS classification and exposure index data. Result: From the result of screening risk assessment for 642 chemicals, we extracted a list of 13 priority chemicals for HREC performed by the ISHA. A priority list of 27 chemicals which have carcinogen, mutagen and/or reproductive toxicity but not controlled by the ISHA was suggested for additional evaluation as "chemicals for special management".