• Title/Summary/Keyword: safety limits

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Comparison of MBA and HPLC Post-column Oxidation Methods for the Quantification of Paralytic Shellfish Poisoning Toxins

  • Yu, Hongsik;Lim, Keun Sik;Song, Ki Cheol;Lee, Ka Jeong;Lee, Mi Ae;Kim, Ji Hoe
    • Fisheries and Aquatic Sciences
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    • 제16권3호
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    • pp.159-164
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    • 2013
  • The mouse bioassay and high performance liquid chromatography (HPLC) post-column oxidation method are different methods of quantifying paralytic shellfish poisoning toxins. In this study, we compared their ability to accurately quantify the toxicity levels in two types of field sample (oysters and mussels) with different toxin profiles for routine regulatory monitoring. A total of 72 samples were analyzed by both methods, 44 of which gave negative results, with readings under the limit of detection of the mouse bioassay ($40{\mu}g/100g$ saxitoxin [STX] eq). In 14 oysters, the major toxin components were gonyautoxin (GTX) 1, -2, -3, -4, -5, decarbamoylgonyautoxin-2 (dcGTX2), and decarbamoylsaxitoxin (dcSTX), while 14 mussels tested positive for dcSTX, GTX2, -3, -4, -5, dcGTX2, neosaxitoxin (NEO), STX, and dcSTX. When the results obtained by both methods were compared in two matrices, a better correlation ($r^2=0.9478$) was obtained for mussels than for oysters ($r^2=0.8244$). Additional studies are therefore needed in oysters to investigate the differences in the results obtained by both methods. Importantly, some samples with toxin levels around the legal limit gave inconsistent results using HPLC-based techniques, which could have a strong economic impact due to enforced harvest area closure. It should therefore be determined if all paralytic shellfish poisoning toxins can be quantified accurately by HPLC, and if the uncertainties of the method lead to doubts regarding regulatory limits.

Investigation of the LPG Gas Explosion of a Welding And Cutting Torch at a Construction Site

  • Lee, Su-kyung;Lee, Jung-hoon;Song, Dong-woo
    • Korean Chemical Engineering Research
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    • 제56권6호
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    • pp.811-818
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    • 2018
  • A fire and explosion accident caused by a liquefied petroleum gas (LPG) welding and cutting torch gas leak occurred 10 m underground at the site of reinforcement work for bridge columns, killing four people and seriously injuring ten. We conducted a comprehensive investigation into the accident to identify the fundamental causes of the explosion by analyzing the structure of the construction site and the properties of propane, which was the main component of LPG welding and cutting work used at the site. The range between the lower and upper explosion limits of leaking LPG for welding and cutting work was examined using Le Chatelier's formula; the behavior of LPG concentration change, which included dispersion and concentration change, was analyzed using the fire dynamic simulator (FDS). We concluded that the primary cause of the accident was combustible LPG that leaked from a welding and cutting torch and formed a explosion range between the lower and upper limits. When the LPG contacted the flame of the welding and cutting torch, LPG explosion occurred. The LPG explosion power calculation was verified by the blast effect computation program developed by the Department of Defense Explosive Safety Board (DDESB). According to the fire simulation results, we concluded that the welding and cutting torch LPG leak caused the gas explosion. This study is useful for safety management to prevent accidents caused by LPG welding and cutting work at construction sites.

Principles of Risk Assessment: Overview of the Risk Assessment Process

  • Doull John
    • 대한예방의학회:학술대회논문집
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    • 대한예방의학회 1994년도 교수 연수회(환경)
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    • pp.402-403
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    • 1994
  • There are three different approaches to chemical risk assessment which will be considered in this paper. The U.S. Environmental Protection Agency(EPA) Cancer Risk Assessment includes some of the approaches used by the International Agency for Research on Cancer (IARC). The Agency for Toxic Substances and Disease Registry (ATSDR) effort is an evaluated database approach similar to that used in the National Institute for Occupational Safety and Health (NIOSH) Criteria Documents and in the documentations prepared by the Occupational Safety and Health Administration (OSHA) for the Permissible Exposure Limits (PELs) and those of the American Conference of Governmental Industrial Hygienists (ACGIH) for the Threshold Limit Values (TLVs). A third approach is used by the Committee on Toxicology.

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용액론에 의한 가연성혼합용액의 폭발한계 예측 (Prediction of Explosive Limits for Flammable Mixture Solution by Means of Solution Theory)

  • 하동명
    • 한국산업안전학회:학술대회논문집
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    • 한국안전학회 1999년도 춘계 학술논문발표회 논문집
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    • pp.69-72
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    • 1999
  • 공정상에서 화재 및 폭발위험을 최소화하기 위해서는 공정의 안전과 최적화조작이 이루워 져야 하는데, 우선 작업 조건하에서 취급물질의 연소특성치 파악이 필요하다. 화학공정에 있어서 설계의 요지는 공정모사 프로그램이다. 최근에는 공정모사 프로그램에 응용하기 위해 열역학적 물성치 데이터베이스 연구에 화재ㆍ폭발 특성치 연구가 활발히 진행되고 있다. 이는 공장을 건설하기 전에 안전성 평가가 이루어져야 하기 때문이다. (중략)

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노말알킬케톤류의 화염온도 예측 및 폭발한계의 온도의존성

  • 하동명;이수경
    • 한국산업안전학회:학술대회논문집
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    • 한국안전학회 2000년도 춘계 학술논문발표회 논문집
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    • pp.140-143
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    • 2000
  • 연소특성은 인화성용제들(석유류 및 알코올류 등)의 취급, 저장, 수송에서 포함되어 있는 잠재 위험성을 평가할 때 고려된다. 여러 연소특성 가운데 폭발한계 (explosive limits)는 가연성물질(가스 및 증기)을 다루는 공정 설계 시 고려해야 할 중요한 변수로써, 발화원이 존재할 때 가연성가스와 옹기가 혼합하여 일정농도범위 내에서만 연소가 이루어지는 혼합범위를 말한다. (중략)

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수치모사에 의한 파라핀족 탄화수소의 연소상한계의 예측 (Prediction of Upper Flammability Limit of Paraffinic Hydrocarbons by Numerical Simulation)

  • 하동명
    • 한국안전학회지
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    • 제8권3호
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    • pp.50-55
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    • 1993
  • A new model for predicting upper flammability limits( UFL ) of paraffinic hydrocarbons is developed, based on statistics and numerical simulation. With the proposed model, UFL have been calculated for 24 compounds, and when compared with experimental data, this model produced average percent error of 2.96%. When compared to established methods published by Spakowski and Zabetakis, this model produced more accurate results.

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양론계수와 연소열을 이용한 Ether류의 폭발하한계 예측

  • 하동명;최용찬;이성진;이수경
    • 한국산업안전학회:학술대회논문집
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    • 한국안전학회 2003년도 춘계 학술논문발표회 논문집
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    • pp.428-433
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    • 2003
  • 화재 및 폭발 특성치로 인화점, 최소발화온도, 폭발한계, 최소발화에너지, 연소열 등을 들 수 있다. 연소특성은 인화성용제들(석유류 및 알코올류 등)의 취급, 저장, 수송에서 포함되어 있는 잠재 위험성을 평가할 때 고려된다. 여러 연소특성 가운데 폭발한계(explosive limits)는 가연성물질(가스 및 증기)을 다루는 공정 설계 시 고려해야 할 중요한 변수로써, 발화원이 존재할 때 가연성가스와 공기가 혼합하여 일정 농도범위 내에서만 연소가 이루어지는 혼합범위를 말한다.(중략)

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안정적인 전력공급을 위한 안전 (Safety for the Stable Electric Power Supply)

  • 윤재건
    • 한국연소학회:학술대회논문집
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    • 한국연소학회 2012년도 제45회 KOSCO SYMPOSIUM 초록집
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    • pp.163-165
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    • 2012
  • Korea is now the country with shortage of electric power because of limits on power usage of businesses to prevent a possible blackout during the summer and winter. This is due to the failure to predict the total power usage. And the futhermore several accidents in the power plant during the overhaul maintenance threaten the stable power supply. Accidents were due to the combustion of low calorific coal and the shortage of the maintenance time. We should not incur a future great loss by pursuing a present small profit.

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메탄 및 LNG 폭발 특성에 관한 연구

  • 하동명
    • 한국산업안전학회:학술대회논문집
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    • 한국안전학회 1998년도 추계 학술논문발표회 논문집
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    • pp.273-278
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    • 1998
  • 여러가지 연소특성들은 가연성물질의 취급함에 있어 밸브조작실수, 배관접합부 파손. 저장 및 수송의 부주의로 주위에 공기와 혼합되면 화재 및 폭발이 발생할 수 있는 잠재적 위험성을 평가할 수 있다. 여러 연소특성 가운데 폭발(연소)한계(explosive (flammable) limits)는 가연성물질(가스 및 증기)을 다루는 화학공정에 있어 설계시 고려해야 할 가장 중요한 변수로써, 발화원이 존재할 때 가연성가스와 공기가 혼합하여 일정 농도 범위내에서만 연소가 이루어지는 혼합범위를 말한다. (중략)

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컴퓨터 내장형 냉각시스템 개발 (Development for Inserted Type Coling System in Computer)

  • 이현용;임선종
    • 대한안전경영과학회:학술대회논문집
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    • 대한안전경영과학회 2009년도 추계학술대회
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    • pp.399-404
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    • 2009
  • The research for computer cooling system has been researched briskly at home and abroad. Most of computer cooling systems are the air cooling method using cooling fan. The air cooling system are most widely used for low cost and easy installation but have limits in cooling. The water cooling system are good for cooling efficiency but bad for installation. This paper presents the developing for cooling system to be inserted in computer using thermoelectric module.

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