• Title/Summary/Keyword: safety limits

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Management of Veterinary Drug Residues in Food (식품 중 잔류동물용의약품의 안전관리)

  • Oh, Jae-Ho;Kwon, Chan-Hyeok;Jeon, Jong-Sup;Choi, Dong-Mi
    • Korean Journal of Environmental Agriculture
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    • v.28 no.3
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    • pp.310-325
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    • 2009
  • Veterinary drugs have been used to prevent livestock diseases for many years. In spite of having advantages, sometimes indiscriminate application, overdose and abuse may cause risk for human. Therefore, management and risk assessment of veterinary drugs become essential to ensure food safety. So the National Veterinary Research & Quarantine Service (NVRQS) impose on registration for use of veterinary drugs also Korea Food and Drug Administration (KFDA) fixed the maximum residue limits (MRLs) for veterinary drugs in food. Basically, KFDA set MRLs based on the veterinary drugs residual data. Moreover, KFDA estimates the theoretical maximum daily intake (TMDI) with food consumption data and population mean body weight. Recently, 116 veterinary drug MRLs including banned veterinary drugs have been established and other 32 veterinary drugs MRLs will be established within 2009. In 2010, MRLs among antibiotics and synthetic antibacterial agents in livestock fishery products (including milk and eggs) and honey (including royal jelly and propolis) which have not been set in Korea Food Code and Codex Alimentarius Commission (CAC) will be regulated as uniform limit (0.03 mg/kg). In future, veterinary drugs will be controlled strictly to strengthen public health by improving analytical method.

Radiolysis of Paraffin Encapsulation Wax (파라핀 고화체의 방사선적 가수분해)

  • Kim, Chang-Lak;Lee, Myung-Chan;Park, Won-Jae;Suk, Tae-Won;Burns William G.
    • Journal of Radiation Protection and Research
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    • v.20 no.4
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    • pp.237-243
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    • 1995
  • An estimate is made on the potential generation rate of H: from radiolysis of the Paraffin-wax encapsulant Proposed for the solidified liquid concentrate wasteform. The results show that the radiolytic Production of $H_2$ from paraffin-wax-encapsulated waste is dominated by the radiation energy released from $^{60}Co$. The radiolytic production of $H_2$ will proceed at an initial rate equivalent to aproximately $4.4{\times}10^2cm^3yr^1$ in 200 litre drums that are partly filled with 120 litres of encapsulated waste. The gas production rate will fall to a value of $7.2cm^3yr^1$ after 100 years. The lower flammable limit for $H_2$ in air will be reached in about 25 years and the lower explosive limit for $H_2$ in air would not be reached in 1000years. The timescale in which these safety-related limits are reached is strongly dependent on the level of filling of each waste drum. A reduction of the air space inside each drum would reduce the time required to reach the lower flammable limit.

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The Safety Assessment of Aflatoxins and Deoxynivalenol in Cereals and Their Products (곡류 및 그 가공품 중 아플라톡신과 데옥시니발레놀의 안전성 평가)

  • Kim, Young-Su;Kim, Young-Sug;Kim, Myeong-Gil;Lee, Seong-Bong;Lee, Ju-Ye;Oh, Sang-Hun;Jung, You-Jung;Seo, My-Young;Sung, Jin-Hee;Lee, Woan;Lee, Jong-Bok;Yoon, Mi-Hye
    • Journal of Food Hygiene and Safety
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    • v.28 no.2
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    • pp.158-167
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    • 2013
  • This study was carried out to assess the safety of cereals and their products (20 species, 205 samples) distributed in Gyeonggi province by analyzing contamination levels such as exposure frequency of Aflatoxins and Deoxynivalenol (DON). Aflatoxins were detected in 16 (8%) samples in total with a range of 0.01~27.88 ${\mu}g/kg$, including 3 of 9 bake flour (33%), 2 of 6 dried corn (33%), 3 of 12 frying flour (25%) and 2 of 11 sorghum (18%). DON was found in 56 (27%) samples including 11 of 13 adlay (85%), 6 of 8 wheat (75%), 6 of 10 processed corn for popcorn (60%), 6 of 11 sorghum (55%) and 7 of 16 barley (44%) with a range of 2.2~754.4 ${\mu}g/kg$. In particular, both Aflatoxins and DON were detected in 8 samples (2 millet, 2 wheat, 1 sorghum, 1 adlay, 1 dried corn, 1 bake flour) simultaneously. As a result of this study, we found that an adult is exposed to Aflatoxins of $0.80({\times})10^{-3}{\mu}g/kg$ b.w./day and DON of 0.18 ${\mu}g/kg$ b.w./day. The quantity of exposure to DON amounted to 18.5 percentage level compared with PMTDI 1 ${\mu}g/kg$ b.w./day suggested on JECFA, therefore we can assess that the possibility of health risks by intake cereals distributed in Gyeonggi province is low. However the concentration of Aflatoxins in one dried corn was 27.88 ${\mu}g/kg$ which was over the maximum residue limits (MRL) suggested on internal and external level, the monitoring about mycotoxin should be conducted on continuously.

Exposure Assessment of Solvents and Toluene Diisocyanates among Polyurethane Waterproofing Workers in the Construction industry (건설현장 우레탄 방수작업자의 휘발성 유기화합물 및 톨루엔 디이소시아네이트 노출평가)

  • Park, Hyunhee;Hwang, Eunsong;Ro, Jiwon;Jang, Kwangmyung;Park, Seunghyun;Yoon, Chungsik
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.30 no.2
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    • pp.134-152
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    • 2020
  • Objectives: The objective of this study was to evaluate volatile organic compounds (VOCs) and toluene diisocyanates (TDIs) exposure among polyurethane waterproofing workers in the construction industry. Methods: Task-based personal air samplings were carried out at seven construction sites using organic vapor monitor for VOCs (n=88) and glass fiber filters coated with 1-(2-pyridyl)piperazine(1-2PP) for TDIs (n=81). The concentration of VOCs and TDIs were shown for four different work types(mixing paint, primer roller painting, urethane resin spread painting, painter assistant) at five different worksites (rooftop, ground parking lot, piloti, bathroom, and swimming pool). The two TDI sampling methods (filter vs impinger) were evaluated in parallel to compare the concentrations. Results: The geometric mean(GM) concentration of VOCs Exposure Index (EI) was highest for primer roller painting (1.4), followed in order by, urethane resin spread painting (0.85), mixing paint (0.53), and painter assistant (0.35) by work types. The GM of VOCs EI was highest for bathroom (1.4) followed in order by, swimming pool (0.85), piloti (0.89), ground parking lot (0.82) and rooftop (0.57) by worksites. The GM of 2,4-/2,6-TDI concentration was 0.052 ppb and 0.432 ppb each. There was no statistical difference in TDIs concentrations among worksites. The concentration of 2,6-TDI was ten times higher than that of 2,4-TDI. The concentration of 2,6-TDI by impinger method was 5.7 times higher than that by filter method. Conclusions: In this study, we found 38.6% of the VOCs samples exceeded the occupational exposure limits and 19.8% of the 2,6-TDI samples exceeded 1 ppb among polyurethane waterproofing workers. The most important determinants that increase the concentration of VOCs and TDIs was indoor environment and primer painting work.

A Simple Seismic Vulnerability Sorting Method for Electric Power Utility Tunnels (전력구의 간편 지진취약도 선별법)

  • Kang, Choonghyun;Huh, Jungwon;Park, Inn-Joon;Hwang, Kyeong Min;Jang, Jung Bum
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.22 no.5
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    • pp.110-118
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    • 2018
  • Due to recent earthquakes, there is a growing awareness that Korea is not a safe zone for earthquakes any more. Therefore, the review of various aspects of the seismic safety of the infrastructures are being carried out. Because of the characteristics of the underground structure buried in the ground, the electric power utility tunnels must be considered not only for the inertia and load capacity of the structure itself but also the characteristics of the surrounding soils. An extensive and accurate numerical analysis is inevitably required in order to consider the interaction with the ground, but it is difficult to apply the soil-structure interaction analyses, which generally requires high cost and extensive time, to all electric power utility tunnel structures. In this study, the major design variables including soil characteristics are considered as independent variables, and the seismic safety factor, which is the result of the numerical analysis, is considered as a dependent variable. Thus, a method is proposed to select vulnerable electric power utility tunnels with low seismic safety factor while excluding costly and time-consuming numerical analyses through the direct correlation analysis between independent and dependent variables. Equations of boundary limits were derived based on the distribution of the seismic safety factor and the cover depth and rebar amounts with high correlation relationship. Consequently, a very efficient and simple approach is proposed to select vulnerable electric power utility tunnels without intensive numerical analyses. Among the 108 electric power utility tunnels that were investigated in this paper, 30% were screened as fragile structures, and it is confirmed that the screening method is valid by checking the safety factors of the fragile structure. The approach is relatively very simple to use and easy to expand, and can be conveniently applied to additional data to be obtained in the future.

A Study on Speed Limit Rules under Sailing Regulations - Focusing on the Perspective of VTS Control - (항법상 속력의 제한규칙에 관한 고찰 - VTS의 관제 관점에서 -)

  • Chong, Dae-Yul
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.28 no.2
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    • pp.254-261
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    • 2022
  • Every vessel shall proceed at a safe speed to avoid collision. Additionally, every vessel shall comply with the speed limit rules in the territorial water and internal waters of Korea. The VTS operator shall properly control the compliance of the vessel with the safe speed and speed limit rules. Safe speed under the COLREG 1972 is not explicitly stipulated in knots. However, under the Domestic law for traffic safety-specific sea areas, etc., the speed limit is specified in knots and complied with. This speed limit rule is mainly based on the 'speed made good over the ground'; however, in some places, it is based on the 'speed making way through the water'. In this paper, I analyzed marine accidents that occurred in the past 5 years and the rate of violation of speed limits. Furthermore, I reviewed safe speed under the COLREG 1972, speed limit rules under domestic and foreign laws, and cases of non-compliance with safe speed in the judgment of the Korea Maritime Safety Tribunal. Resultantly, I suggested in this paper that the speed limit rules in the domestic law must be observed by vessels to prevent marine accidents, and the rules which are stipulated in terms of 'speed making way through the water' must be revised as 'speed made good over the ground' such that the vessels can easily comply with them and the VTS operator can control the vessel properly.

Development of Analytical Method for Detection of Fungicide Validamycin A Residues in Agricultural Products Using LC-MS/MS (LC-MS/MS를 이용한 농산물 중 살균제 Validamycin A의 시험법 개발)

  • Park, Ji-Su;Do, Jung-Ah;Lee, Han Sol;Park, Shin-min;Cho, Sung Min;Shin, Hye-Sun;Jang, Dong Eun;Cho, Myong-Shik;Jung, Yong-hyun;Lee, Kangbong
    • Journal of Food Hygiene and Safety
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    • v.34 no.1
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    • pp.22-29
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    • 2019
  • Validamycin A is an aminoglycoside fungicide produced by Streptomyces hygroscopicus that inhibits trehalase. The purpose of this study was to develop a method for detecting validamycin A in agricultural samples to establish MRL values for use in Korea. The validamycin A residues in samples were extracted using methanol/water (50/50, v/v) and purified with a hydrophilic-lipophilic balance (HLB) cartridges. The analyte was quantified and confirmed by liquid chromatograph-tandem mass spectrometer (LC-MS/MS) in positive ion mode using multiple reaction monitoring (MRM). Matrix-matched calibration curves were linear over the calibration ranges (0.005~0.5 ng) into a blank extract with $R^2$ > 0.99. The limits of detection and quantification were 0.005 and 0.01 mg/kg, respectively. For validation validamycin A, recovery studies were carried out three different concentration levels (LOQ, $LOQ{\times}10$, $LOQ{\times}50$, n = 5) with five replicates at each level. The average recovery range was from 72.5~118.3%, with relative standard deviation (RSD) less than 10.3%. All values were consistent with the criteria ranges requested in the Codex guidelines (CAC/GL 40-1993, 2003) and the NIFDS (National Institute of Food and Drug Safety) guideline (2016). Therefore, the proposed analytical method is accurate, effective and sensitive for validamycin A determination in agricultural commodities.

A Study on the Development of Sweeping Arm System for Oil Recovery by Small Vessel (소형 선박을 이용한 기름방제용 스위핑 암 시스템 개발에 관한 연구)

  • Han, Won-Heui
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.19 no.2
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    • pp.219-224
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    • 2013
  • In the case of occurring marine oil pollution, it is the most effective way that to prepare all the necessary response resources in advance and to respond to incidents, but there are limits in reality. Therefore, may be an important alternative ways to use a fishing vessel registered in the affected area by massive marine oil pollution efficiently. In the United States and other developed countries, it is can be found that temporary response program by local fishing vessels(VOO program) has been developed and operated. This study was examined for sweeping arm system suitable for domestic small fishing vessels. The selected small vessel was as the model of Coastal gill-net and compound fishing vessel with classes of 2.5~3.5tons, length 8~9m, breath 2.5~2.8m, horsepower 200~250 HP and FRP materials. The developed equipment was designed that can be easily mounted on the model ship and portable structure. For increasing the field practicality, the weight of each part was composed less than 10kg for easy assembly and disassembly.

Residue Patterns of Active Ingredients Derived from Melia Azedarach, Nerium Ndicum, and Coptis Chinensis in Rice Using LC-MS/MS (LC-MS/MS를 이용한 멀구슬, 협죽도, 황련 유래 활성성분의 벼 중 잔류양상 연구)

  • Park, Joon-Seong;Nam, Hyo-Song;Kim, Yong-Hwan;Kim, Do-ik;Kim, Sun-Am
    • Korean Journal of Environmental Agriculture
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    • v.34 no.2
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    • pp.128-133
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    • 2015
  • BACKGROUND: Plant extracts have been used as environment friendly agricultural materials for organic farming in South Korea. However safety evaluation on the plant extracts was not properly tested. The aim of this study was to evaluate safety of the extracts from Melia azedarach, Nerium indicum and Coptis chinensis on cultivating rice. METHODS AND RESULTS: Pant extarcts 300-fold diluted were treated on rice, and residues of M. azedarach, N. indicum and C. chinensis were determined. The analytes from the rice samples were detected by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). The method was validated, and good linearities ($r^2=0.995-0.998$), specificity, and recoveries were obtained. Limits of detection were 0.01 mg/kg for all of the target compounds. Recoveries were 79.3-118.3% at 0.1 mg/kg and 75.2-111.5% at 0.5 mg/kg. The residue levels were below 0.030 mg/kg for azadirachtin, 0.320 mg/kg for oleandrin and 1.460 mg/kg for berberine. CONCLUSION(S): The extracts of M. azedarach, N. indicum and C. chinensis contained azadirachtin, oleandrin and berberine as an active ingredient, respectively. The residue of three active ingredients dramatically decreased after treatment in all fruits, stems and roots of rice.

A Study of Age Rating Criteria for Outdoor Augmented Reality Game (실외형 증강현실 게임의 등급분류기준에 관한 연구)

  • Kang, Ju-young;Lee, Hwan-soo
    • Journal of Digital Convergence
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    • v.14 no.10
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    • pp.439-447
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    • 2016
  • Interest in Augmented Reality (AR) game $Pok{\acute{e}}mon$ GO is getting heightened. However, based on its characteristic, various direct and indirect problems are highlighted, thus increasing concerns. Although the game is not formally released domestically, there are limits in national game classification to apply on such outdoor Augmented Reality game. This paper will examine the problematic cases regarding Pokemon GO and analyze internal and external game classification system to discuss safe gaming measures for domestic users. In result of examining cases, need for adding 'physical danger' in current game classification system for user's safety was shown. As the government's game regulation is being eased, appearance of a variety of games using Augmented Reality technology in near future is predicable. Therefore it is important to prepare improvement of game classification system as a pre-safety measure, and it is expected to bring positive effect on game usage and industrial growth through safe game usage.